FI885869A0 - CYCLOSPORINE AND FAR OIL DESSION FRAMSTAELLNING. - Google Patents

CYCLOSPORINE AND FAR OIL DESSION FRAMSTAELLNING.

Info

Publication number: FI885869A0
Authority: FI; Finland
Prior art keywords: dession; framstaellning; cyclosporine; far oil; far
Prior art date: 1987-12-21

Application number

FI885869A

Other languages

Finnish (fi)

Other versions

FI89065C (en

FI885869L (en

FI89065B (en

Inventor

Daniel Giron

Martin List

Friedrich Richter

Yasuyuki Uike

Hans Peter Weber

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-12-21

Filing date

1988-12-19

Publication date

1988-12-19

1988-12-19 Application filed by Sandoz Ag filed Critical Sandoz Ag

1988-12-19 Publication of FI885869A0 publication Critical patent/FI885869A0/en

1989-06-22 Publication of FI885869L publication Critical patent/FI885869L/en

1993-04-30 Application granted granted Critical

1993-04-30 Publication of FI89065B publication Critical patent/FI89065B/en

1993-09-30 Publication of FI89065C publication Critical patent/FI89065C/en

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
108010036949 Cyclosporine Proteins 0.000 title 1
229960001265 ciclosporin Drugs 0.000 title 1
229930182912 cyclosporin Natural products 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Transplantation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

FI885869A 1987-12-21 1988-12-19 FREQUENCY REFRIGERATION FOR CYCLOSPORIC CRYSTAL FORM FI89065C (en)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date
US13623087A	1987-12-21	1987-12-21
US13623087		1987-12-21
US17261388A	1988-03-24	1988-03-24
US17261388		1988-03-24
US21254888A	1988-06-28	1988-06-28
US21254888		1988-06-28

Publications (4)

Publication Number	Publication Date
FI885869A0 true FI885869A0 (en)	1988-12-19
FI885869L FI885869L (en)	1989-06-22
FI89065B FI89065B (en)	1993-04-30
FI89065C FI89065C (en)	1993-09-30

Family

ID=27384838

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI885869A FI89065C (en)	1987-12-21	1988-12-19	FREQUENCY REFRIGERATION FOR CYCLOSPORIC CRYSTAL FORM

Country Status (27)

Country	Link
JP (1)	JPH0791316B2 (en)
KR (1)	KR100188305B1 (en)
AT (1)	AT403163B (en)
AU (1)	AU626274B2 (en)
BE (1)	BE1002665A4 (en)
CA (1)	CA1341396C (en)
CH (1)	CH677926A5 (en)
CY (1)	CY1799A (en)
DE (1)	DE3843054C2 (en)
DK (1)	DK175220B1 (en)
ES (1)	ES2012580A6 (en)
FI (1)	FI89065C (en)
FR (1)	FR2624863B1 (en)
GB (1)	GB2211848B (en)
GR (1)	GR1002486B (en)
HK (1)	HK102894A (en)
HU (1)	HU203564B (en)
IE (1)	IE62006B1 (en)
IL (1)	IL88719A0 (en)
IT (1)	IT1235356B (en)
LU (1)	LU87409A1 (en)
MY (1)	MY103943A (en)
NL (1)	NL195096C (en)
NO (1)	NO177228C (en)
NZ (1)	NZ227384A (en)
SE (1)	SE503174C2 (en)
SG (1)	SG99494G (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5639724A (en) *	1984-07-24	1997-06-17	Sandoz Ltd.	Cyclosporin galenic forms
US6007840A (en) *	1988-09-16	1999-12-28	Novartis Ag	Pharmaceutical compositions comprising cyclosporins
GB2222770B (en)	1988-09-16	1992-07-29	Sandoz Ltd	Pharmaceutical compositions containing cyclosporins
US7081445B2 (en)	1989-02-20	2006-07-25	Novartis Ag	Cyclosporin galenic forms
US5294604A (en) *	1989-12-20	1994-03-15	The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	Method of treating ocular diseases by periocular administration of cyclosporine A or G
GB9105705D0 (en) *	1991-03-18	1991-05-01	Sandoz Ltd	Improvements in or relating to organic compounds
US6262022B1 (en)	1992-06-25	2001-07-17	Novartis Ag	Pharmaceutical compositions containing cyclosporin as the active agent
EP0642332B1 (en) *	1992-05-13	1997-01-15	Sandoz Ltd.	Ophthalmic compositions containing a cyclosporin
ES2168271T3 (en)	1992-09-25	2002-06-16	Novartis Ag	PHARMACEUTICAL COMPOSITIONS CONTAINING CYCLOSPORINS.
PT789580E (en)	1994-11-03	2002-09-30	Novartis Ag	CYCLOSPORINE FORMULATIONS FOR ORAL ADMINISTRATION WITH SIMPLE COMPOSITION AND HIGH BIODISPONIBILITY AND PROCESS FOR ITS PRODUCTION
US5962019A (en) *	1995-08-25	1999-10-05	Sangstat Medical Corporation	Oral cyclosporin formulations
US5766629A (en)	1995-08-25	1998-06-16	Sangstat Medical Corporation	Oral cyclosporin formulations
DE19549852B4 (en)	1995-11-29	2009-06-04	Novartis Ag	Cyclosporin containing preparations
US6262054B1 (en) *	1996-02-01	2001-07-17	Sloan-Kettering Institute Of Cancer Research	Combination therapy method for treating breast cancer using edatrexate
EP0988046B1 (en)	1997-01-30	2004-09-15	Novartis AG	Oil-free pharmaceutical compositions containing cyclosporin a
TW581681B (en)	1998-02-20	2004-04-01	Nektar Therapeutics	Liquid crystal forms of cyclosporin
US7732404B2 (en)	1999-12-30	2010-06-08	Dexcel Ltd	Pro-nanodispersion for the delivery of cyclosporin
JP2007518804A (en)	2004-01-20	2007-07-12	アラーガン、インコーポレイテッド	Composition for topical ophthalmic treatment preferably containing triamcinolone acetonide and hyaluronic acid
CN1763084B (en) *	2005-10-11	2010-04-21	山东新时代药业有限公司	Preparation method of high-purity cyclosporine A
CA2836946C (en) *	2011-05-27	2017-08-01	Allergan, Inc.	A crystalline form of cyclosporine a, methods of preparation, and methods for use thereof
BR112014011744A2 (en)	2011-11-15	2017-05-02	Allergan Inc	sustainable action formulation of cyclosporine form 2
RU2630970C2 (en)	2011-11-15	2017-09-15	Аллерган, Инк.	Autoclavable form 2 cyclosporin a portion
EP2779994B1 (en) *	2011-11-15	2020-02-19	Allergan, Inc.	Suspensions of cyclosporin a form 2
WO2013074608A1 (en)	2011-11-15	2013-05-23	Allergan, Inc.	Cyclosporine a form 2 and method of making same
WO2024085235A1 (en) *	2022-10-20	2024-04-25	中外製薬株式会社	Method for producing cyclic peptide crystals

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH614931A5 (en) *	1975-11-04	1979-12-28	Sandoz Ag
CH640519A5 (en) *	1976-04-09	1984-01-13	Sandoz Ag	Process for preparing a modified form of the antibiotic S 7481/F-1
US4117118A (en) *	1976-04-09	1978-09-26	Sandoz Ltd.	Organic compounds
DE2819094A1 (en) *	1977-05-10	1978-11-23	Sandoz Ag	CYCLOSPORIN DERIVATIVES, THEIR USE AND MANUFACTURING
CH637124A5 (en) *	1978-10-18	1983-07-15	Sandoz Ag	Antibiotic, its preparation and use

1988
- 1988-12-09 HU HU886374A patent/HU203564B/en unknown
- 1988-12-19 FR FR888816886A patent/FR2624863B1/en not_active Expired - Lifetime
- 1988-12-19 AU AU27055/88A patent/AU626274B2/en not_active Expired
- 1988-12-19 NZ NZ227384A patent/NZ227384A/en unknown
- 1988-12-19 SE SE8804570A patent/SE503174C2/en not_active IP Right Cessation
- 1988-12-19 CH CH4687/88A patent/CH677926A5/de not_active IP Right Cessation
- 1988-12-19 IE IE377988A patent/IE62006B1/en not_active IP Right Cessation
- 1988-12-19 NO NO885625A patent/NO177228C/en unknown
- 1988-12-19 FI FI885869A patent/FI89065C/en not_active IP Right Cessation
- 1988-12-19 IL IL88719A patent/IL88719A0/en unknown
- 1988-12-19 DK DK198807054A patent/DK175220B1/en not_active IP Right Cessation
- 1988-12-19 GB GB8829556A patent/GB2211848B/en not_active Expired - Lifetime
- 1988-12-20 AT AT0309588A patent/AT403163B/en not_active IP Right Cessation
- 1988-12-20 KR KR1019880017194A patent/KR100188305B1/en not_active Expired - Lifetime
- 1988-12-20 IT IT8848690A patent/IT1235356B/en active
- 1988-12-20 LU LU87409A patent/LU87409A1/en unknown
- 1988-12-20 JP JP63321857A patent/JPH0791316B2/en not_active Expired - Lifetime
- 1988-12-20 GR GR880100850A patent/GR1002486B/en not_active IP Right Cessation
- 1988-12-20 BE BE8801421A patent/BE1002665A4/en not_active IP Right Cessation
- 1988-12-21 NL NL8803125A patent/NL195096C/en active Search and Examination
- 1988-12-21 CA CA000586611A patent/CA1341396C/en not_active Expired - Fee Related
- 1988-12-21 ES ES8803887A patent/ES2012580A6/en not_active Expired - Lifetime
- 1988-12-21 DE DE3843054A patent/DE3843054C2/en not_active Expired - Lifetime
- 1988-12-21 MY MYPI88001495A patent/MY103943A/en unknown
1994
- 1994-07-21 SG SG99494A patent/SG99494G/en unknown
- 1994-09-22 HK HK102894A patent/HK102894A/en not_active IP Right Cessation
1995
- 1995-02-17 CY CY179995A patent/CY1799A/en unknown

Also Published As

Publication number	Publication date
IE883779L (en)	1989-06-21
IE62006B1 (en)	1994-12-14
NO177228B (en)	1995-05-02
DK705488A (en)	1989-06-22
GB2211848B (en)	1991-11-06
SE8804570D0 (en)	1988-12-19
CH677926A5 (en)	1991-07-15
IT1235356B (en)	1992-06-30
FR2624863B1 (en)	1991-04-26
DK705488D0 (en)	1988-12-19
AT403163B (en)	1997-11-25
HUT49893A (en)	1989-11-28
FR2624863A1 (en)	1989-06-23
JPH0791316B2 (en)	1995-10-04
GR1002486B (en)	1996-12-09
HU203564B (en)	1991-08-28
ES2012580A6 (en)	1990-04-01
KR100188305B1 (en)	1999-06-01
GB2211848A (en)	1989-07-12
NL195096C (en)	2004-02-09
AU2705588A (en)	1989-06-22
NO885625L (en)	1989-06-22
IT8848690A0 (en)	1988-12-20
AU626274B2 (en)	1992-07-30
GR880100850A (en)	1994-03-31
SG99494G (en)	1994-10-28
HK102894A (en)	1994-09-30
GB8829556D0 (en)	1989-02-08
IL88719A0 (en)	1989-07-31
MY103943A (en)	1993-10-30
JPH01211598A (en)	1989-08-24
NL8803125A (en)	1989-07-17
CY1799A (en)	1995-02-17
KR890009975A (en)	1989-08-05
NO177228C (en)	1995-08-09
ATA309588A (en)	1997-04-15
SE503174C2 (en)	1996-04-15
NZ227384A (en)	1991-09-25
BE1002665A4 (en)	1991-04-30
DE3843054A1 (en)	1989-07-27
DE3843054C2 (en)	2003-08-21
NO885625D0 (en)	1988-12-19
CA1341396C (en)	2002-11-05
FI89065C (en)	1993-09-30
LU87409A1 (en)	1989-07-07
SE8804570L (en)	1989-06-22
DK175220B1 (en)	2004-07-12
FI885869L (en)	1989-06-22
FI89065B (en)	1993-04-30

Publication	Publication Date	Title
FI885869A0 (en)	1988-12-19	CYCLOSPORINE AND FAR OIL DESSION FRAMSTAELLNING.
FI880929L (en)	1988-09-10	DESTRUCTURERAD STAERKELSE OCH FOERFARANDE FOER DESS FRAMSTAELLNING.
FI883436A0 (en)	1988-07-20	VAETSKEBEHAOLLARE OCH DESS FRAMSTAELLNINGSFOERFARANDE.
FI882813A7 (en)	1988-12-16	PYRAZOLOPYRIDINFOERENING OCH FOERFARANDE FOER DESS FRAMSTAELLNING.
FI884617L (en)	1989-04-10	ISOTONISK -3-FETTSYRAHALTIG FETTEMULSION OCH DESS ANVAENDNING.
FI884749A7 (en)	1989-04-15	AUTOGENISK TVAOKAMMARBLODTRANSFUSIONSANORDNING OCH FOERFARANDE FOER DESS ANVAENDNING.
FI885148A0 (en)	1988-11-09	SIKTKORG OCH FOERFARANDE FOER DESS TILLVERKNING.
FI881372A0 (en)	1988-03-22	KATALYTUNDERLAG OCH FOERFARANDE FOER DESS FRAMSTAELLNING.
FI884318A0 (en)	1988-09-21	IMIDAZOPYRIDINFOERENING OCH FOERFARANDE FOER DESS FRAMSTAELLNING.
FI884256A0 (en)	1988-09-15	LIVSMEDELSFOERPACKNING OCH FOERFARANDE FOER DESS FRAMSTAELLNING.
FI882245L (en)	1988-11-15	MATERIALBANA OCH FOERFARANDE FOER DESS FRAMSTAELLNING.
FI862608A0 (en)	1986-06-18	THIAZOLIN-4 (S) -CARBOXYL SYRADERIVES AND FAR OIL FAR OIL DERAS FRAMSTAELLNING.
FI883383L (en)	1989-01-18	HJAELPMEDELSKOMPOSITION FOER GOEDSLINGSMEDEL OCH DESS ANVAENDNING.
FI880453A0 (en)	1988-02-01	NARKOSMEDELKOMPOSITION OCH FOERFARANDE FOER DESS ANVAENDNING.
FI881339A0 (en)	1988-03-21	KOMPAKTLYSROER OCH FOERFARANDE FOER DESS FRAMSTAELLNING.
FI882873L (en)	1988-12-31	TIOFENDERIVAT OCH FOERFARANDE FOER DESS FRAMSTAELLNING.
FI884912A0 (en)	1988-10-24	MODIFIED OIL ELLEDANDE POLYMERER.
FI880543A0 (en)	1988-02-05	LYFTSTROPP OCH FOERFARANDE FOER DESS FRAMSTAELLNING.
FI882874L (en)	1989-01-10	TIOFENDERIVAT OCH FOERFARANDE FOER DESS FRAMSTAELLNING.
FI873285A0 (en)	1987-07-28	FIBERARMERAT ROERELEMENT OCH FOERFARANDE FOER DESS TILLVERKNING.
FI884004A0 (en)	1988-08-31	BENZOFURANDERIVAT OCH FOERFARANDE FOER DESS FRAMSTAELLNING.
FI880875L (en)	1988-08-25	HAORKOSMETISK SAMMANSAETTNING OCH DESS FRAMSTAELLNINGSFOERFARANDE.
FI870757A7 (en)	1988-08-24	LYFTSTROPP OCH FOERFARANDE FOER DESS TILLVERKNING.
FI872837L (en)	1988-12-27	SKIVMATERIAL OCH FOERFARANDE FOER DESS FRAMSTAELLNING.
FI870761L (en)	1988-08-24	FILMAGGREGAT OCH FOERFARANDE FOER DESS FRAMSTAELLNING.

Legal Events

Date	Code	Title	Description
1988-12-19	FG	Patent granted	Owner name: NOVARTIS AG
1993-04-01	BB	Publication of examined application
1997-09-03	PC	Transfer of assignment of patent	Owner name: NOVARTIS AG
2004-08-31	FG	Patent granted	Owner name: NOVARTIS AG
2009-01-20	MA	Patent expired