FI803253L - Bensodiazepinfoereningar och deras anvaendning som laekemedel - Google Patents

Bensodiazepinfoereningar och deras anvaendning som laekemedel

Info

Publication number: FI803253L
Authority: FI; Finland
Prior art keywords: bensodiazepinfoereningar; och deras; deras anvaendning; anvaendning som; som laekemedel
Prior art date: 1979-10-16

Application number

FI803253A

Other languages

English (en)

Other versions

FI67550B (fi

FI67550C (fi

Inventor

Jiban Kumar Chakrabarti

Terrence Michael Hotten

Original Assignee

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-10-16

Filing date

1980-10-15

Publication date

1981-04-17

1980-10-15 Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd

1981-04-17 Publication of FI803253L publication Critical patent/FI803253L/fi

1984-12-31 Publication of FI67550B publication Critical patent/FI67550B/fi

1985-04-10 Application granted granted Critical

1985-04-10 Publication of FI67550C publication Critical patent/FI67550C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

FI803253A 1979-10-16 1980-10-15 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 2,10-dihydro-4-piperazinyl-pyrazolo(3,4-b)(1,5)bensodiazepinderivat FI67550C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB7935846		1979-10-16
GB7935846		1979-10-16

Publications (3)

Publication Number	Publication Date
FI803253L true FI803253L (fi)	1981-04-17
FI67550B FI67550B (fi)	1984-12-31
FI67550C FI67550C (fi)	1985-04-10

Family

ID=10508540

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI803253A FI67550C (fi)	1979-10-16	1980-10-15	Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 2,10-dihydro-4-piperazinyl-pyrazolo(3,4-b)(1,5)bensodiazepinderivat

Country Status (33)

Country	Link
US (3)	US4404137A (fi)
EP (1)	EP0027390B1 (fi)
JP (1)	JPS5663987A (fi)
KR (2)	KR850000471B1 (fi)
AR (2)	AR228041A1 (fi)
AT (1)	AT373889B (fi)
AU (1)	AU538500B2 (fi)
BE (1)	BE885729A (fi)
BG (2)	BG34907A3 (fi)
CA (1)	CA1159056A (fi)
CH (1)	CH646700A5 (fi)
CS (1)	CS244409B2 (fi)
DD (1)	DD153692A5 (fi)
DE (1)	DE3068706D1 (fi)
DK (1)	DK437480A (fi)
ES (1)	ES8106905A1 (fi)
FI (1)	FI67550C (fi)
FR (1)	FR2467851A1 (fi)
GB (1)	GB8327127D0 (fi)
GR (1)	GR70720B (fi)
HU (1)	HU182213B (fi)
IE (1)	IE50358B1 (fi)
IL (1)	IL61264A (fi)
IT (1)	IT1143047B (fi)
LU (1)	LU82853A1 (fi)
MX (1)	MX6233E (fi)
NZ (1)	NZ195248A (fi)
PH (2)	PH16288A (fi)
PL (2)	PL126824B1 (fi)
PT (1)	PT71913B (fi)
RO (2)	RO81351B (fi)
YU (1)	YU261580A (fi)
ZA (1)	ZA806342B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4404137A (en) *	1979-10-16	1983-09-13	Lilly Industries Limited	Pyrazolo [3,4-b][1,5]benzodiazepine compounds
US4431589A (en) *	1980-12-11	1984-02-14	Lilly House	Benzodiazepine compounds and their use as pharmaceuticals
US4596799A (en) *	1985-01-29	1986-06-24	Ciba-Geigy Corporation	9H-pyrrolo[2,1-c]-1,2,4-triazolo[4,3-a][1,4]benzodiazepines
TW219896B (fi) *	1988-07-07	1994-02-01	Duphar Int Res
GB8819059D0 (en) *	1988-08-11	1988-09-14	Lilly Industries Ltd	Benzodiazepine compounds & their use as pharmaceuticals
US5637584A (en) *	1995-03-24	1997-06-10	Eli Lilly And Company	Solvate of olanzapine
US5631250A (en) *	1995-03-24	1997-05-20	Eli Lilly And Company	Process and solvate of 2-methyl-thieno-benzodiazepine
US20050250767A1 (en) *	2003-01-23	2005-11-10	Weiner David M	Use of N-desmethylclozapine to treat human neuropsychiatric disease
KR20050092123A (ko) *	2003-01-23	2005-09-20	아카디아 파마슈티칼스 인코포레이티드	Ｎ-데스메틸클로자핀의 인간의 신경정신성 질환의 치료용도
US20050085463A1 (en) *	2003-01-23	2005-04-21	Weiner David M.	Use of N-desmethylclozapine to treat human neuropsychiatric disease
ES2324713T3 (es) *	2003-12-22	2009-08-13	Acadia Pharmaceuticals Inc.	Analogos de diaril(a,d)ciclohepteno amino-sustituidos como agonistas muscarinicos y metodos de tratamiento de trastornos neuropsiquiatricos.
JP2007536216A (ja) *	2004-04-01	2007-12-13	アカディアファーマシューティカルズ，インコーポレーテッド	固体ｎ−デスメチルクロザピンおよびその結晶形を合成および単離する方法
WO2007053618A1 (en) *	2005-10-31	2007-05-10	Acadia Pharmaceuticals Inc.	Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders
JP5438482B2 (ja) *	2009-12-03	2014-03-12	Ｊｕｋｉ株式会社	ミシン、ミシンの縫製データ編集装置及びミシンの縫製データ編集プログラム

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3450694A (en) *	1966-02-23	1969-06-17	Abbott Lab	Substituted benzoxazepines and benzothiazepines
US3758479A (en) *	1967-03-22	1973-09-11	Sandoz Ag	Nitro and sulphamoyl substituted dibenzodiazepines
DE1795183B1 (de) *	1968-08-20	1972-07-20	Thomae Gmbh Dr K	5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
CA918659A (en) *	1969-07-31	1973-01-09	Yoshitomi Pharmaceutical Industries	11-(4-substituted-1-piperazinyl)-dibenzo (b,f) (1,4) thiazepines
US4115568A (en) *	1974-11-26	1978-09-19	Lilly Industries Limited	Thieno[3,2-b]-[1,5]benzodiazepines
US4172831A (en) *	1974-11-26	1979-10-30	Lilly Industries Limited	Thieno-benzodiazepines
US3951981A (en) *	1975-02-24	1976-04-20	American Cyanamid Company	Substituted benzodiazepines and method of use
US3953430A (en) *	1975-02-24	1976-04-27	American Cyanamid Company	Substituted benzodiazepin-10-ones and method of use
DE2707270A1 (de) *	1977-02-19	1978-08-24	Hoechst Ag	Pyrazolo-diazepine und verfahren zu ihrer herstellung
DE2707269A1 (de) *	1977-02-19	1978-08-24	Hoechst Ag	Heterocyclische stickstoffverbindungen und verfahren zu ihrer herstellung
US4097597A (en) *	1977-02-23	1978-06-27	Abbott Laboratories	Dibenzo b,e! 1,4!diazepines
IT7851496A0 (it) *	1977-10-31	1978-10-13	Sandoz Ag	Menti pirazinobenzossazepine loro preparazione e loro impiego quali medica
CH643263A5 (de) *	1979-05-11	1984-05-30	Sandoz Ag	Benzodiazepine, ihre herstellung und verwendung.
EP0023707B1 (de) *	1979-08-03	1986-04-30	Byk Gulden Lomberg Chemische Fabrik GmbH	Substituierte Tetraazatricyclen, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende Arzneimittel
US4404137A (en) *	1979-10-16	1983-09-13	Lilly Industries Limited	Pyrazolo [3,4-b][1,5]benzodiazepine compounds

1980
- 1980-10-02 US US06/193,200 patent/US4404137A/en not_active Expired - Lifetime
- 1980-10-11 GR GR63138A patent/GR70720B/el unknown
- 1980-10-13 IL IL61264A patent/IL61264A/xx unknown
- 1980-10-13 RO RO102349A patent/RO81351B/ro unknown
- 1980-10-13 NZ NZ195248A patent/NZ195248A/xx unknown
- 1980-10-13 FR FR8021823A patent/FR2467851A1/fr active Granted
- 1980-10-13 RO RO108967A patent/RO85822B/ro unknown
- 1980-10-13 YU YU02615/80A patent/YU261580A/xx unknown
- 1980-10-13 CS CS806938A patent/CS244409B2/cs unknown
- 1980-10-13 PH PH24717A patent/PH16288A/en unknown
- 1980-10-13 MX MX809093U patent/MX6233E/es unknown
- 1980-10-14 AU AU63252/80A patent/AU538500B2/en not_active Ceased
- 1980-10-14 CH CH763980A patent/CH646700A5/fr not_active IP Right Cessation
- 1980-10-14 PT PT71913A patent/PT71913B/pt unknown
- 1980-10-14 AT AT0510180A patent/AT373889B/de not_active IP Right Cessation
- 1980-10-14 IT IT49899/80A patent/IT1143047B/it active
- 1980-10-14 CA CA000362328A patent/CA1159056A/en not_active Expired
- 1980-10-15 PL PL1980227306A patent/PL126824B1/pl unknown
- 1980-10-15 BG BG049366A patent/BG34907A3/xx unknown
- 1980-10-15 ES ES495948A patent/ES8106905A1/es not_active Expired
- 1980-10-15 FI FI803253A patent/FI67550C/fi not_active IP Right Cessation
- 1980-10-15 BE BE6/47291A patent/BE885729A/fr not_active IP Right Cessation
- 1980-10-15 KR KR1019800003960A patent/KR850000471B1/ko not_active Expired
- 1980-10-15 IE IE2135/80A patent/IE50358B1/en unknown
- 1980-10-15 BG BG057344A patent/BG35042A3/xx unknown
- 1980-10-15 HU HU802502A patent/HU182213B/hu not_active IP Right Cessation
- 1980-10-15 JP JP14423180A patent/JPS5663987A/ja active Pending
- 1980-10-15 DE DE8080303649T patent/DE3068706D1/de not_active Expired
- 1980-10-15 ZA ZA00806342A patent/ZA806342B/xx unknown
- 1980-10-15 EP EP80303649A patent/EP0027390B1/en not_active Expired
- 1980-10-15 DK DK437480A patent/DK437480A/da not_active Application Discontinuation
- 1980-10-15 PL PL1980231270A patent/PL135044B1/pl unknown
- 1980-10-15 LU LU82853A patent/LU82853A1/fr unknown
- 1980-10-15 DD DD80224618A patent/DD153692A5/de unknown
- 1980-10-16 AR AR282893A patent/AR228041A1/es active
1982
- 1982-07-21 AR AR290034A patent/AR228101A1/es active
- 1982-07-28 PH PH27643A patent/PH17759A/en unknown
- 1982-09-29 US US06/426,580 patent/US4486591A/en not_active Expired - Fee Related
1983
- 1983-10-11 GB GB838327127A patent/GB8327127D0/en active Pending
1984
- 1984-07-24 KR KR1019840004388A patent/KR850000472B1/ko not_active Expired
- 1984-08-06 US US06/638,181 patent/US4542131A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ATA510180A (de)	1983-07-15
KR830004300A (ko)	1983-07-09
DK437480A (da)	1981-04-17
HU182213B (en)	1983-12-28
LU82853A1 (fr)	1982-05-10
EP0027390B1 (en)	1984-07-25
PT71913B (en)	1981-08-31
EP0027390A1 (en)	1981-04-22
IL61264A0 (en)	1980-12-31
AU538500B2 (en)	1984-08-16
AR228101A1 (es)	1983-01-14
KR850000471B1 (ko)	1985-04-08
BG35042A3 (en)	1983-01-16
IT1143047B (it)	1986-10-22
PL231270A1 (fi)	1981-12-23
ES495948A0 (es)	1981-09-16
IE50358B1 (en)	1986-04-02
AU6325280A (en)	1981-04-30
CS244409B2 (en)	1986-07-17
PL227306A1 (fi)	1981-09-18
RO81351B (ro)	1983-02-28
NZ195248A (en)	1983-11-18
MX6233E (es)	1985-01-14
DD153692A5 (de)	1982-01-27
CA1159056A (en)	1983-12-20
JPS5663987A (en)	1981-05-30
US4542131A (en)	1985-09-17
YU261580A (en)	1983-12-31
BE885729A (fr)	1981-04-15
PL135044B1 (en)	1985-09-30
PH17759A (en)	1984-12-05
GB8327127D0 (en)	1983-11-09
IL61264A (en)	1985-08-30
FR2467851A1 (fr)	1981-04-30
IT8049899A0 (it)	1980-10-14
AT373889B (de)	1984-02-27
BG34907A3 (en)	1983-12-15
FR2467851B1 (fi)	1985-04-05
PT71913A (en)	1980-11-01
US4404137A (en)	1983-09-13
CH646700A5 (fr)	1984-12-14
KR850000472B1 (ko)	1985-04-08
RO85822B (ro)	1984-11-30
ES8106905A1 (es)	1981-09-16
US4486591A (en)	1984-12-04
GR70720B (fi)	1983-01-18
KR850001463A (ko)	1985-03-18
ZA806342B (en)	1982-05-26
AR228041A1 (es)	1983-01-14
FI67550B (fi)	1984-12-31
RO81351A (ro)	1983-02-15
FI67550C (fi)	1985-04-10
PL126824B1 (en)	1983-09-30
DE3068706D1 (en)	1984-08-30
RO85822A (ro)	1984-11-25
PH16288A (en)	1983-09-05
IE802135L (en)	1981-04-16

Publication	Publication Date	Title
FI65437B (fi)	1984-01-31	Som herbicid och tillvaextregulator foer vaexter anvaendbart natriumseskviglyfosat
FI802920A7 (fi)	1981-03-23	Foerfarande och anordning foer automatisk korvstoppning med anvaendning av syntetiskt slangmaterial som korvskinn
FI800717A7 (fi)	1980-09-10	Bergbultningsfoerfarande och roerformig utvidgningsbult
FI803558L (fi)	1981-05-20	7-acylamino-3-vinylcefalosporansyraderivat och foerfarande foer deras framstaellning
FI800900A7 (fi)	1980-09-23	Glycinamid-derivater deras framstaellning och deras anvaendning
FI802670A7 (fi)	1981-02-28	Vattenhaltiga smoerjmedel som innehaoller ditiofosfater
FI802590A7 (fi)	1981-02-25	Clavulansyrasalter foerfarande foer framstaellning och anvaendning daerav
FI800823A7 (fi)	1980-09-21	Farmaceutiska heterocykliska kompositioner och blandningar
FI801303A7 (fi)	1980-11-12	Substituerade fenylkarbonyler oximer och karboxioximer
FI801748A7 (fi)	1980-12-06	Saett och anordning foer avstaondsmaetning
FI801491A7 (fi)	1980-11-18	Substratkomposition och anvaendning daerav
FI793201A7 (fi)	1981-04-16	Pappers kalanderingsfoerfarande foer papper och kalander som tillaempar foerfarandet
FI802985A7 (fi)	1981-03-25	Acylerade triazol-ny-fluorpinakolylderivat foerfarande foer framstaellning av dessa och anvaendningen av dessa som fungicider
FI803253L (fi)	1981-04-17	Bensodiazepinfoereningar och deras anvaendning som laekemedel
FI802951A7 (fi)	1981-03-22	Mesofasloesning innehaollande cellulosaderivat och oorganisk syra
FI801494A7 (fi)	1980-11-11	Fluorerade 1-triazolyl-butan-derivat foerfarande foer deras framstaellning och anvaendningen av dessa som fungicider
FI791941A7 (fi)	1979-12-20	Boranhydridloesningar och deras anvaendning som haerdare foer resoler
FI792244A7 (fi)	1980-02-08	Bis-aminopyridiner foerfarande foer framstaellning daerav och anvaendning daerav som oxidationshaorfaergaemnen
FI800191A7 (fi)	1980-07-25	Detektor som reagerar foer vaetskestroemningar
FI800939A7 (fi)	1980-09-27	Skyddsstroemstaellare foer laeckstroem som reagerar aeven foer likstroem
FI802396A7 (fi)	1981-02-03	Braennbara sammansaettningar och foerfaranden foer deras framstaellning
FI802189A7 (fi)	1981-01-12	Acetylacetoxyalkyl-allyleter deras framstaellning och anvaendning
FI803028A7 (fi)	1981-03-27	Acetoxymetyl-penam-foereningar som beta-laktamasinhibitorer
FI800224A7 (fi)	1980-07-30	2-hydroxi-naftalinderivat och anvaendningen av dessa som kopplingskomponenter i diazotypiefieringsmaterial
FI801518A7 (fi)	1980-11-16	Prefabricerad laboratorie-enhet och oktananalysator

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: LILLY INDUSTRIES LIMITED