FI120817B - Intrabukkaalisesti liukenevat puristustuotteet ja näiden valmistusmenetelmä - Google Patents

Intrabukkaalisesti liukenevat puristustuotteet ja näiden valmistusmenetelmä Download PDF

Info

Publication number: FI120817B
Authority: FI; Finland
Prior art keywords: saccharide; soluble; preparation; press; active ingredient
Prior art date: 1994-01-31

Application number

FI963022A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI963022A0 (fi

FI963022L (fi

Inventor

Muneo Fukui

Yoshinori Masuda

Takao Mizumoto

Original Assignee

Astellas Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-31

Filing date

1996-07-31

Publication date

2010-03-31

1996-07-31 Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc

1996-07-31 Publication of FI963022A0 publication Critical patent/FI963022A0/fi

1996-07-31 Publication of FI963022L publication Critical patent/FI963022L/fi

2010-03-31 Application granted granted Critical

2010-03-31 Publication of FI120817B publication Critical patent/FI120817B/fi

Links

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VWBQYTRBTXKKOG-IYNICTALSA-M pravastatin sodium Chemical compound [Na+].C1=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC([O-])=O)[C@H]2[C@@H](OC(=O)[C@@H](C)CC)C[C@H](O)C=C21 VWBQYTRBTXKKOG-IYNICTALSA-M 0.000 description 1
229960001495 pravastatin sodium Drugs 0.000 description 1
229960004856 prazepam Drugs 0.000 description 1
229960005205 prednisolone Drugs 0.000 description 1
OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 description 1
229940002612 prodrug Drugs 0.000 description 1
239000000651 prodrug Substances 0.000 description 1
239000000186 progesterone Substances 0.000 description 1
229960003387 progesterone Drugs 0.000 description 1
229960003712 propranolol Drugs 0.000 description 1
JNTOKFNBDFMTIV-UHFFFAOYSA-N propyl nitrate Chemical compound CCCO[N+]([O-])=O JNTOKFNBDFMTIV-UHFFFAOYSA-N 0.000 description 1
235000019423 pullulan Nutrition 0.000 description 1
229960001404 quinidine Drugs 0.000 description 1
GGWBHVILAJZWKJ-KJEVSKRMSA-N ranitidine hydrochloride Chemical compound [H+].[Cl-].[O-][N+](=O)\C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 GGWBHVILAJZWKJ-KJEVSKRMSA-N 0.000 description 1
HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 description 1
238000007670 refining Methods 0.000 description 1
230000001850 reproductive effect Effects 0.000 description 1
238000011160 research Methods 0.000 description 1
229960003147 reserpine Drugs 0.000 description 1
BJOIZNZVOZKDIG-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C([C]5C=CC(OC)=CC5=N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 BJOIZNZVOZKDIG-MDEJGZGSSA-N 0.000 description 1
206010039083 rhinitis Diseases 0.000 description 1
MDMGHDFNKNZPAU-UHFFFAOYSA-N roserpine Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(OC(C)=O)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 MDMGHDFNKNZPAU-UHFFFAOYSA-N 0.000 description 1
229940085605 saccharin sodium Drugs 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
229960002101 secretin Drugs 0.000 description 1
OWMZNFCDEHGFEP-NFBCVYDUSA-N secretin human Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O)[C@@H](C)O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)C1=CC=CC=C1 OWMZNFCDEHGFEP-NFBCVYDUSA-N 0.000 description 1
229960002855 simvastatin Drugs 0.000 description 1
RYMZZMVNJRMUDD-HGQWONQESA-N simvastatin Chemical compound C([C@H]1[C@@H](C)C=CC2=C[C@H](C)C[C@@H]([C@H]12)OC(=O)C(C)(C)CC)C[C@@H]1C[C@@H](O)CC(=O)O1 RYMZZMVNJRMUDD-HGQWONQESA-N 0.000 description 1
IZTQOLKUZKXIRV-YRVFCXMDSA-N sincalide Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(OS(O)(=O)=O)C=C1 IZTQOLKUZKXIRV-YRVFCXMDSA-N 0.000 description 1
229940125706 skeletal muscle relaxant agent Drugs 0.000 description 1
239000001509 sodium citrate Substances 0.000 description 1
NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
AEQFSUDEHCCHBT-UHFFFAOYSA-M sodium valproate Chemical compound [Na+].CCCC(C([O-])=O)CCC AEQFSUDEHCCHBT-UHFFFAOYSA-M 0.000 description 1
229940084026 sodium valproate Drugs 0.000 description 1
KSRLIXGNPXAZHD-HAZZGOGXSA-M sodium;3-[(e)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-5-oxo-4h-imidazol-2-olate Chemical compound [Na+].[O-]C1=NC(=O)CN1\N=C\C1=CC=C(C=2C=CC(=CC=2)[N+]([O-])=O)O1 KSRLIXGNPXAZHD-HAZZGOGXSA-M 0.000 description 1
239000002689 soil Substances 0.000 description 1
239000008247 solid mixture Substances 0.000 description 1
239000007944 soluble tablet Substances 0.000 description 1
229960002920 sorbitol Drugs 0.000 description 1
230000002269 spontaneous effect Effects 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
239000008117 stearic acid Substances 0.000 description 1
230000003637 steroidlike Effects 0.000 description 1
230000004936 stimulating effect Effects 0.000 description 1
238000003860 storage Methods 0.000 description 1
229960005322 streptomycin Drugs 0.000 description 1
229950003874 sulfamonomethoxine Drugs 0.000 description 1
FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 description 1
229940124530 sulfonamide Drugs 0.000 description 1
239000000725 suspension Substances 0.000 description 1
238000013268 sustained release Methods 0.000 description 1
239000003765 sweetening agent Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000006188 syrup Substances 0.000 description 1
239000007916 tablet composition Substances 0.000 description 1
239000000454 talc Substances 0.000 description 1
229910052623 talc Inorganic materials 0.000 description 1
229960003198 tamsulosin hydrochloride Drugs 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
229950006156 teprenone Drugs 0.000 description 1
229960000351 terfenadine Drugs 0.000 description 1
229960003604 testosterone Drugs 0.000 description 1
239000000892 thaumatin Substances 0.000 description 1
235000010436 thaumatin Nutrition 0.000 description 1
229940126585 therapeutic drug Drugs 0.000 description 1
229960003279 thiopental Drugs 0.000 description 1
229960000488 tizanidine Drugs 0.000 description 1
XFYDIVBRZNQMJC-UHFFFAOYSA-N tizanidine Chemical compound ClC=1C=CC2=NSN=C2C=1NC1=NCCN1 XFYDIVBRZNQMJC-UHFFFAOYSA-N 0.000 description 1
YXFVVABEGXRONW-UHFFFAOYSA-N toluene Substances CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 1
229960005294 triamcinolone Drugs 0.000 description 1
GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 description 1
JOFWLTCLBGQGBO-UHFFFAOYSA-N triazolam Chemical compound C12=CC(Cl)=CC=C2N2C(C)=NN=C2CN=C1C1=CC=CC=C1Cl JOFWLTCLBGQGBO-UHFFFAOYSA-N 0.000 description 1
229960003386 triazolam Drugs 0.000 description 1
LMJSLTNSBFUCMU-UHFFFAOYSA-N trichlormethiazide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC2=C1NC(C(Cl)Cl)NS2(=O)=O LMJSLTNSBFUCMU-UHFFFAOYSA-N 0.000 description 1
229960004813 trichlormethiazide Drugs 0.000 description 1
GPMXUUPHFNMNDH-UHFFFAOYSA-N trifluperidol Chemical compound C1CC(O)(C=2C=C(C=CC=2)C(F)(F)F)CCN1CCCC(=O)C1=CC=C(F)C=C1 GPMXUUPHFNMNDH-UHFFFAOYSA-N 0.000 description 1
229960002341 trifluperidol Drugs 0.000 description 1
102000003390 tumor necrosis factor Human genes 0.000 description 1
231100000397 ulcer Toxicity 0.000 description 1
229940035893 uracil Drugs 0.000 description 1
230000002485 urinary effect Effects 0.000 description 1
229960003726 vasopressin Drugs 0.000 description 1
239000000273 veterinary drug Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Nutrition Science (AREA)
Biophysics (AREA)
Zoology (AREA)
Physiology (AREA)
Medicinal Preparation (AREA)
Materials For Medical Uses (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Cosmetics (AREA)
Detergent Compositions (AREA)
Compositions Of Macromolecular Compounds (AREA)
Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Dental Preparations (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Separation Using Semi-Permeable Membranes (AREA)
Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)

FI963022A 1994-01-31 1996-07-31 Intrabukkaalisesti liukenevat puristustuotteet ja näiden valmistusmenetelmä FI120817B (fi)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
JP1011294		1994-01-31
JP1011294		1994-01-31
JP8665294		1994-04-25
JP8665294		1994-04-25
PCT/JP1995/000102 WO1995020380A1 (en)	1994-01-31	1995-01-27	Intraorally soluble compressed molding and process for producing the same
JP9500102		1995-01-27

Publications (3)

Publication Number	Publication Date
FI963022A0 FI963022A0 (fi)	1996-07-31
FI963022L FI963022L (fi)	1996-07-31
FI120817B true FI120817B (fi)	2010-03-31

Family

ID=26345308

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI963022A FI120817B (fi)	1994-01-31	1996-07-31	Intrabukkaalisesti liukenevat puristustuotteet ja näiden valmistusmenetelmä

Country Status (21)

Country	Link
EP (1)	EP0745382B1 (zh)
JP (1)	JP3122141B2 (zh)
KR (1)	KR100386391B1 (zh)
CN (1)	CN1182838C (zh)
AT (1)	ATE253899T1 (zh)
AU (1)	AU699715B2 (zh)
CA (1)	CA2179382C (zh)
DE (1)	DE69532110T2 (zh)
DK (1)	DK0745382T3 (zh)
ES (1)	ES2210280T3 (zh)
FI (1)	FI120817B (zh)
HU (1)	HUT74908A (zh)
MX (1)	MX9603035A (zh)
NO (1)	NO316662B1 (zh)
NZ (1)	NZ278678A (zh)
PH (1)	PH31467A (zh)
PL (1)	PL187160B1 (zh)
PT (1)	PT745382E (zh)
RU (1)	RU2147227C1 (zh)
TW (1)	TW391880B (zh)
WO (1)	WO1995020380A1 (zh)

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DE102004022928A1 (de) *	2004-05-10	2005-12-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pulver enthaltend neuartige Oligosacharidgemische und Verfahren zu deren Herstellung
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1995
- 1995-01-27 TW TW084100735A patent/TW391880B/zh not_active IP Right Cessation
- 1995-01-27 PH PH49851A patent/PH31467A/en unknown
- 1995-01-27 WO PCT/JP1995/000102 patent/WO1995020380A1/ja not_active Ceased
- 1995-01-27 DE DE69532110T patent/DE69532110T2/de not_active Expired - Lifetime
- 1995-01-27 PL PL95315552A patent/PL187160B1/pl not_active IP Right Cessation
- 1995-01-27 KR KR1019960704132A patent/KR100386391B1/ko not_active Expired - Lifetime
- 1995-01-27 EP EP95906533A patent/EP0745382B1/en not_active Expired - Lifetime
- 1995-01-27 JP JP07519980A patent/JP3122141B2/ja not_active Expired - Lifetime
- 1995-01-27 AT AT95906533T patent/ATE253899T1/de active
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- 1995-01-27 CN CNB951914081A patent/CN1182838C/zh not_active Expired - Lifetime
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- 1995-01-27 NZ NZ278678A patent/NZ278678A/en not_active IP Right Cessation
- 1995-01-27 PT PT95906533T patent/PT745382E/pt unknown
- 1995-01-27 HU HU9602083A patent/HUT74908A/hu not_active Application Discontinuation
- 1995-01-27 DK DK95906533T patent/DK0745382T3/da active
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- 1995-01-27 RU RU96117252/14A patent/RU2147227C1/ru not_active IP Right Cessation
- 1995-01-27 AU AU14671/95A patent/AU699715B2/en not_active Ceased
1996
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Also Published As

Publication number	Publication date
HUT74908A (en)	1997-03-28
TW391880B (en)	2000-06-01
NZ278678A (en)	1998-03-25
CN1182838C (zh)	2005-01-05
NO963180D0 (no)	1996-07-30
DE69532110D1 (de)	2003-12-18
CN1139878A (zh)	1997-01-08
FI963022A0 (fi)	1996-07-31
EP0745382B1 (en)	2003-11-12
MX9603035A (es)	1997-05-31
CA2179382C (en)	2009-11-10
PH31467A (en)	1998-11-03
AU1467195A (en)	1995-08-15
CA2179382A1 (en)	1995-08-03
HU9602083D0 (en)	1996-09-30
PT745382E (pt)	2004-04-30
PL187160B1 (pl)	2004-05-31
KR100386391B1 (ko)	2003-08-30
RU2147227C1 (ru)	2000-04-10
DE69532110T2 (de)	2004-09-09
EP0745382A4 (en)	1997-10-29
NO316662B1 (no)	2004-03-22
EP0745382A1 (en)	1996-12-04
ATE253899T1 (de)	2003-11-15
NO963180L (no)	1996-09-30
DK0745382T3 (da)	2004-03-22
JP3122141B2 (ja)	2001-01-09
ES2210280T3 (es)	2004-07-01
FI963022L (fi)	1996-07-31
PL315552A1 (en)	1996-11-12
WO1995020380A1 (en)	1995-08-03
AU699715B2 (en)	1998-12-10

Publication	Publication Date	Title
FI120817B (fi)	2010-03-31	Intrabukkaalisesti liukenevat puristustuotteet ja näiden valmistusmenetelmä
US5576014A (en)	1996-11-19	Intrabuccally dissolving compressed moldings and production process thereof
EP1366759B1 (en)	2009-06-03	Tablets quickly disintegrating in oral cavity
RU2189227C2 (ru)	2002-09-20	Быстро распадающиеся прессованные в формах материалы и способ их получения
JPWO1995020380A1 (ja)	1996-06-25	口腔内溶解型圧縮成型物及びその製造法
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RU2273472C2 (ru)	2006-04-10	Лекарственный состав, быстро распадающийся в ротовой полости, и способ его изготовления
US20050147666A1 (en)	2005-07-07	Tablets quickly disintegrating in oral cavity
JP4802436B2 (ja)	2011-10-26	口腔内崩壊型組成物及び口腔内崩壊型製剤
WO2002047607A2 (en)	2002-06-20	Process for the preparation of a fast dissolving dosage form
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JP2005029557A (ja)	2005-02-03	口腔内速崩壊性錠剤およびその製造方法
JP2008133294A (ja)	2008-06-12	口腔内崩壊型錠剤
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Alanezi	2014	Development of an orally disintegrating mini-tablet (ODMTs) containing metoclopramide HCl to enhance patient compliance
Deshmukh et al.	2012	A REVIEW ON FAST DISSOLVING TABLET.
Deshmukh et al.	0	PHARMA SCIENCE MONITOR
Sharma et al.	0	DISCUSSION AND INGREDIENTS OF DIFFERENT TYPES OF TABLETS: A COMPREHENSIVE REVIEW

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