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FI109206B - Interleukiini-1 inhibiittoreita koodittavat DNA-sekvenssit, niitä sisältävät vektorit ja isäntäsolut sekä menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi - Google Patents

Interleukiini-1 inhibiittoreita koodittavat DNA-sekvenssit, niitä sisältävät vektorit ja isäntäsolut sekä menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi Download PDF

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Publication number
FI109206B
FI109206B FI905812A FI905812A FI109206B FI 109206 B FI109206 B FI 109206B FI 905812 A FI905812 A FI 905812A FI 905812 A FI905812 A FI 905812A FI 109206 B FI109206 B FI 109206B
Authority
FI
Finland
Prior art keywords
sequence
amino acid
dna sequence
dna
encoding
Prior art date
Application number
FI905812A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI905812A0 (fi
Inventor
Robert C Thompson
Andreas Sommer
Stephen P Eisenberg
Charles H Hannum
Fenneke G Joslin
William P Arend
Original Assignee
Amgen Inc
Univ Colorado Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc, Univ Colorado Foundation filed Critical Amgen Inc
Publication of FI905812A0 publication Critical patent/FI905812A0/fi
Application granted granted Critical
Publication of FI109206B publication Critical patent/FI109206B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI905812A 1988-05-27 1990-11-26 Interleukiini-1 inhibiittoreita koodittavat DNA-sekvenssit, niitä sisältävät vektorit ja isäntäsolut sekä menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi FI109206B (fi)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US19991588A 1988-05-27 1988-05-27
US19991588 1988-05-27
US23871388A 1988-08-31 1988-08-31
US23871388 1988-08-31
US26653188A 1988-11-03 1988-11-03
US26653188 1988-11-03
US8902275 1989-05-25
PCT/US1989/002275 WO1989011540A1 (en) 1988-05-27 1989-05-25 Interleukin-1 inhibitors

Publications (2)

Publication Number Publication Date
FI905812A0 FI905812A0 (fi) 1990-11-26
FI109206B true FI109206B (fi) 2002-06-14

Family

ID=27394086

Family Applications (2)

Application Number Title Priority Date Filing Date
FI905812A FI109206B (fi) 1988-05-27 1990-11-26 Interleukiini-1 inhibiittoreita koodittavat DNA-sekvenssit, niitä sisältävät vektorit ja isäntäsolut sekä menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi
FI20020545A FI20020545L (fi) 1988-05-27 2002-03-21 Eristetty DNA-molekyyli, joka koodaa interleukiini-1 inhibiittoria, sitä sisältävä vektori ja isäntäsolu, menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi sekä niiden käyttö farmaseuttistenkoostumusten valmistamisessa

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20020545A FI20020545L (fi) 1988-05-27 2002-03-21 Eristetty DNA-molekyyli, joka koodaa interleukiini-1 inhibiittoria, sitä sisältävä vektori ja isäntäsolu, menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi sekä niiden käyttö farmaseuttistenkoostumusten valmistamisessa

Country Status (9)

Country Link
JP (2) JP3192651B2 (da)
KR (1) KR970002917B1 (da)
BR (1) BR8907457A (da)
DK (1) DK172763B1 (da)
FI (2) FI109206B (da)
HU (3) HU215434B (da)
NO (2) NO316122B1 (da)
OA (1) OA09631A (da)
WO (1) WO1989011540A1 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075222A (en) 1988-05-27 1991-12-24 Synergen, Inc. Interleukin-1 inhibitors
US6858409B1 (en) 1988-05-27 2005-02-22 Amgen Inc. Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
US6159460A (en) * 1988-05-27 2000-12-12 Amgen Inc. Method for treating interleukin-1 mediated diseases
US5872095A (en) * 1990-05-01 1999-02-16 Chiron Corporation IL-1 receptor antagonists medicaments
AU655766B2 (en) * 1990-05-01 1995-01-12 Chiron Corporation Interleukin-1 antagonist and uses thereof
US5932537A (en) * 1990-10-09 1999-08-03 Chiron Corporation Method for attenuating a cellular response to IL-1
US5824549A (en) * 1990-10-09 1998-10-20 Chiron Corporation Transformed human T cell
ZA921120B (en) 1991-02-19 1993-01-27 Smithkline Beecham Corp Cytokine inhibitors
US6294170B1 (en) 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
US20030103978A1 (en) 2000-02-23 2003-06-05 Amgen Inc. Selective binding agents of osteoprotegerin binding protein
CN103232539B (zh) 2001-06-26 2015-06-03 安姆根弗里蒙特公司 抗opgl抗体
JP2005507915A (ja) * 2001-10-26 2005-03-24 ノバルティス アクチエンゲゼルシャフト 変形性関節症の処置方法およびその組成物
JP4761710B2 (ja) 2002-04-05 2011-08-31 アムジェン インコーポレイテッド 選択的ｏｐｇｌ経路インヒビターとしてのヒト抗ｏｐｇｌ中和抗体
AU2005267722B2 (en) 2004-08-04 2009-10-08 Amgen Inc. Antibodies to Dkk-1
EP3330292A1 (en) 2007-08-21 2018-06-06 Amgen, Inc Human c-fms antigen binding proteins
US8242074B2 (en) * 2008-09-12 2012-08-14 Xbiotech, Inc. Modulation of the amount or function of pathogenic CD14+CD16+ monocytes
WO2012025910A1 (en) 2010-08-26 2012-03-01 Centro De Investigación Y De Estudios Avanzados Del Instituto Politécnico Nacional METHODS OF DIAGNOSIS AND TREATMENT OF OSTEOARTHRITIS AT EARLY STAGES USING INTERLEUKIN IL-1ß AS EARLY BIOMARKER OF THE DISEASE
ES2600616T3 (es) 2011-03-14 2017-02-10 Phlogo Aps Antagonistas del receptor de la interleucina-1
CN103492416A (zh) 2011-04-15 2014-01-01 默克专利股份公司 用于癌症中使用的抗il-1r1抑制剂
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
WO2015087187A1 (en) 2013-12-10 2015-06-18 Rinat Neuroscience Corp. Anti-sclerostin antibodies
SG11201807596YA (en) 2016-03-08 2018-10-30 Janssen Biotech Inc Gitr antibodies, methods, and uses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2220662A (en) * 1987-08-26 1990-01-17 Biogen Inc Biological materials,processes for producing biological materials and for using such materials in therapy

Also Published As

Publication number Publication date
FI20020545A7 (fi) 2002-03-21
HU893412D0 (en) 1991-05-28
FI905812A0 (fi) 1990-11-26
HU9803037D0 (en) 1999-11-29
HU215434B (hu) 1999-04-28
OA09631A (en) 1993-04-30
NO20014783D0 (no) 2001-10-01
JPH03505279A (ja) 1991-11-21
KR970002917B1 (ko) 1997-03-12
WO1989011540A1 (en) 1989-11-30
FI20020545L (fi) 2002-03-21
DK8591A (da) 1991-01-18
DK8591D0 (da) 1991-01-18
JP2001029093A (ja) 2001-02-06
NO20014783L (no) 1991-01-28
AU3746989A (en) 1989-12-12
BR8907457A (pt) 1991-04-02
DK172763B1 (da) 1999-07-05
AU633831B2 (en) 1993-02-11
NO905090L (no) 1991-01-28
NO316917B1 (no) 2004-06-21
NO316122B1 (no) 2003-12-15
NO905090D0 (no) 1990-11-23
JP3192651B2 (ja) 2001-07-30
HU222810B1 (hu) 2003-11-28

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: AMGEN INC.

Owner name: UNIVERSITY OF COLORADO FOUNDATION, INC.

MA Patent expired