[go: up one dir, main page]

ES8201575A1 - Procedimiento de obtencion de nuevos 2-aminoetanoles - Google Patents

Procedimiento de obtencion de nuevos 2-aminoetanoles

Info

Publication number
ES8201575A1
ES8201575A1 ES497763A ES497763A ES8201575A1 ES 8201575 A1 ES8201575 A1 ES 8201575A1 ES 497763 A ES497763 A ES 497763A ES 497763 A ES497763 A ES 497763A ES 8201575 A1 ES8201575 A1 ES 8201575A1
Authority
ES
Spain
Prior art keywords
aminoethanol
hypotensive
novel
manufacture
containing same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497763A
Other languages
English (en)
Other versions
ES497763A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to ES497763A priority Critical patent/ES497763A0/es
Priority to IT25157/81A priority patent/IT1194116B/it
Priority to DE19813146373 priority patent/DE3146373A1/de
Priority to NL8105310A priority patent/NL8105310A/nl
Priority to FR8121936A priority patent/FR2494584A1/fr
Priority to JP56188271A priority patent/JPS57131784A/ja
Priority to BE0/206637A priority patent/BE891229A/fr
Publication of ES8201575A1 publication Critical patent/ES8201575A1/es
Publication of ES497763A0 publication Critical patent/ES497763A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE 2-AMINOETANOLES DE FORMULA (I), EN QUE X ES OXIGENO, O POR UN GRUPO DE FORMULA (II) O (III), SIENDO Y HIDROGENO, METILO, METOXI O CLORO. SE HACE REACCIONAR PIPERONAL, DE FORMULA (IV) CON YODURO DE METIL MAGNESIO EN UN MEDIO ETEREO. EL COMPUESTO RESULTANTE SE TRATA CON UN N-HALOSUCCINIMIDA, EN UNA MEZCLA DE DIMETIL SULFOXIDO Y AGUA; Y LA HALOHIDRINA OBTENIDA, SE HACE REACCIONAR CON UNA AMINA CICLICA DE FORMULA (V), SIENDO X OXIGENO O UN GRUPO DE FORMULA (III), EN UN DISOLVENTE ORGANICO. EL COMPUESTO DE FORMULA (I), CON X IGUAL A UN GRUPO DE FORMULA (II), SE OBTIENE POR HIDROGENACION CATALITICA DEL PRODUCTO RESULTANTE DEL PROCESO ANTERIOR.
ES497763A 1980-11-24 1980-11-24 Procedimiento de obtencion de nuevos 2-aminoetanoles Granted ES497763A0 (es)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ES497763A ES497763A0 (es) 1980-11-24 1980-11-24 Procedimiento de obtencion de nuevos 2-aminoetanoles
IT25157/81A IT1194116B (it) 1980-11-24 1981-11-18 Procedimento per la preparazione di 2-amminoetanoli
DE19813146373 DE3146373A1 (de) 1980-11-24 1981-11-23 2-aminoaethanolverbindungen, verfahren zu ihrer herstellung und pharmazeutische mittel, die diese verbindungen enthalten
NL8105310A NL8105310A (nl) 1980-11-24 1981-11-24 Werkwijze voor de bereiding van nieuwe 2-aminoethanolen.
FR8121936A FR2494584A1 (fr) 1980-11-24 1981-11-24 Medicaments constitues par de nouveaux 2-aminoethanols et leur procede de fabrication
JP56188271A JPS57131784A (en) 1980-11-24 1981-11-24 Novel 2-aminoethanol, manufacture and hypotensive and analgesic medicine containing same
BE0/206637A BE891229A (fr) 1980-11-24 1981-11-24 Nouveaux 2-aminoethanols et procede pour leur preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES497763A ES497763A0 (es) 1980-11-24 1980-11-24 Procedimiento de obtencion de nuevos 2-aminoetanoles

Publications (2)

Publication Number Publication Date
ES8201575A1 true ES8201575A1 (es) 1981-12-16
ES497763A0 ES497763A0 (es) 1981-12-16

Family

ID=8481576

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497763A Granted ES497763A0 (es) 1980-11-24 1980-11-24 Procedimiento de obtencion de nuevos 2-aminoetanoles

Country Status (7)

Country Link
JP (1) JPS57131784A (es)
BE (1) BE891229A (es)
DE (1) DE3146373A1 (es)
ES (1) ES497763A0 (es)
FR (1) FR2494584A1 (es)
IT (1) IT1194116B (es)
NL (1) NL8105310A (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES502469A0 (es) * 1981-05-13 1982-04-01 Ferrer Int Procedimiento de obtencion de nuevos a-amino derivados ci- clicos del 1-(3',4'-metilendioxifenil)etanol
FR2670491B1 (fr) * 1990-12-14 1993-02-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant.
US6121026A (en) * 1998-08-07 2000-09-19 Merck & Co., Inc. Enantioselective bioreduction using yeast

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3697M (fr) * 1963-05-27 1965-11-22 Ici Ltd Médicaments a base de nouveaux composés hétérocycliques pour le traitement des maladies des arteres coronaires.
NL131192C (es) * 1965-06-16
DE2325633A1 (de) * 1973-05-21 1974-12-12 Boehringer Sohn Ingelheim Piperazinderivate

Also Published As

Publication number Publication date
JPS57131784A (en) 1982-08-14
FR2494584A1 (fr) 1982-05-28
FR2494584B1 (es) 1985-04-19
BE891229A (fr) 1982-03-16
ES497763A0 (es) 1981-12-16
IT1194116B (it) 1988-09-14
IT8125157A0 (it) 1981-11-18
DE3146373A1 (de) 1982-12-02
NL8105310A (nl) 1982-06-16

Similar Documents

Publication Publication Date Title
DE3069408D1 (en) 5-oxo- and 5-thioxoproline derivatives, process for their production and pharmaceutical compositions containing them
ES8407025A1 (es) Un procedimiento para preparar derivados de nicotinamida.
IL57648A (en) 2-substituted-5,9-dimethyl-2'-hydroxy-6,7-benzomorphanes,their preparation and pharmaceutical compositions containing them
ATE37882T1 (de) Cephalosporinverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
ZA926328B (en) Naphthylethylureas and naphthylethylthioureas process for the preparation thereof and pharmaceutical compositions containing them.
IE811250L (en) Imidazole derivatives
ES8702427A1 (es) Un procedimiento para preparar derivados de 1,3-difosfonato
AU540916B2 (en) 3,1 benzoxazin-2-ones
ATE91682T1 (de) Alkansulfonanilid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung.
DE3850603D1 (de) Arylaralkylether, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzung.
ES8106289A1 (es) Procedimiento de preparacion de nuevos derivados del a-fe- nil-2-pirrolidin-metanol
ATE19773T1 (de) Nitroaliphatische verbindungen, verfahren zu deren herstellung und deren verwendung.
DE3170937D1 (en) 2-(1,4-benzodioxan-2-ylalkyl) imidazoles, their preparation and pharmaceutical compositions containing them
DE3160360D1 (en) 5-subsituted 5,10-dihydro-11h-dibenzo(b,e)(1,4)diazepin-11-ones, process for preparing them and medicaments containing them
DE3571984D1 (en) New substituted benzimidazoles, a process for their preparation and their use for inhibiting gastric acid secretion
ES8404852A1 (es) Procedimiento para preparar derivados de acidos isoquinolein-4-carboxilicos
ZA912618B (en) 3-aminochroman derivatives,process for preparing these and pharmaceutical compositions containing them
DE3474298D1 (en) Derivatives of 4-phenyl-4-oxo-buten-2-oic acid, their preparation, medicaments and compositions containing them
ES2001389A6 (es) Procedimiento para preparar derivados de o-toluidina
ES8201575A1 (es) Procedimiento de obtencion de nuevos 2-aminoetanoles
DE3374005D1 (en) 1-methyl-5-nitro-imidazoline derivatives and therapeutic compositions which contain them as active principle
ES474367A1 (es) Procedimiento de preparacion de nuevos derivados del benzo- (d)tiazol.
ES8800156A1 (es) Procedimiento para preparar nuevos derivados 3-piridilmetilnaftilicos
ATE40948T1 (de) Pyridylalkylnitratverbindung, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzung.
ES8801805A1 (es) Procedimiento para la obtencion de nuevos derivados de isoxazol