ES8201575A1 - Novel 2-aminoethanol, manufacture and hypotensive and analgesic medicine containing same - Google Patents
Novel 2-aminoethanol, manufacture and hypotensive and analgesic medicine containing sameInfo
- Publication number
- ES8201575A1 ES8201575A1 ES497763A ES497763A ES8201575A1 ES 8201575 A1 ES8201575 A1 ES 8201575A1 ES 497763 A ES497763 A ES 497763A ES 497763 A ES497763 A ES 497763A ES 8201575 A1 ES8201575 A1 ES 8201575A1
- Authority
- ES
- Spain
- Prior art keywords
- aminoethanol
- hypotensive
- novel
- manufacture
- containing same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 title 2
- 208000001953 Hypotension Diseases 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 208000021822 hypotensive Diseases 0.000 title 1
- 230000001077 hypotensive effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002169 ethanolamines Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
2-Aminoethanol compounds of the general formula I: < IMAGE > in which X represents O, NH or a radical of the formula: < IMAGE > in which Y denotes a hydrogen or chlorine atom or a methyl or methoxy group, and their non-toxic acid addition salts, a process for their preparation and pharmaceutical compositions which contain these compounds.
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES497763A ES497763A0 (en) | 1980-11-24 | 1980-11-24 | PROCEDURE FOR OBTAINING NEW 2-AMINOETHANOLS |
| IT25157/81A IT1194116B (en) | 1980-11-24 | 1981-11-18 | PROCEDURE FOR THE PREPARATION OF 2-AMINOETHANOLS |
| DE19813146373 DE3146373A1 (en) | 1980-11-24 | 1981-11-23 | 2-Aminoethanol compounds, process for their preparation and pharmaceutical compositions which contain these compounds |
| NL8105310A NL8105310A (en) | 1980-11-24 | 1981-11-24 | PROCESS FOR THE PREPARATION OF NEW 2-AMINOETHANOLS. |
| FR8121936A FR2494584A1 (en) | 1980-11-24 | 1981-11-24 | MEDICINES CONSISTING OF NEW 2-AMINOETHANOLS AND THEIR MANUFACTURING PROCESS |
| JP56188271A JPS57131784A (en) | 1980-11-24 | 1981-11-24 | Novel 2-aminoethanol, manufacture and hypotensive and analgesic medicine containing same |
| BE0/206637A BE891229A (en) | 1980-11-24 | 1981-11-24 | NOVEL 2-AMINOETHANOLS AND PROCESS FOR THEIR PREPARATION |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES497763A ES497763A0 (en) | 1980-11-24 | 1980-11-24 | PROCEDURE FOR OBTAINING NEW 2-AMINOETHANOLS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8201575A1 true ES8201575A1 (en) | 1981-12-16 |
| ES497763A0 ES497763A0 (en) | 1981-12-16 |
Family
ID=8481576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES497763A Granted ES497763A0 (en) | 1980-11-24 | 1980-11-24 | PROCEDURE FOR OBTAINING NEW 2-AMINOETHANOLS |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS57131784A (en) |
| BE (1) | BE891229A (en) |
| DE (1) | DE3146373A1 (en) |
| ES (1) | ES497763A0 (en) |
| FR (1) | FR2494584A1 (en) |
| IT (1) | IT1194116B (en) |
| NL (1) | NL8105310A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES502469A0 (en) * | 1981-05-13 | 1982-04-01 | Ferrer Int | PROCEDURE FOR OBTAINING NEW A-AMINO DERIVATIVES CYCLIC FROM 1- (3 ', 4'-METHYLENDIOXIPHENYL) ETHANOL |
| FR2670491B1 (en) * | 1990-12-14 | 1993-02-05 | Adir | NOVEL 1,4-DISUBSTITUTED PIPERAZINES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| US6121026A (en) * | 1998-08-07 | 2000-09-19 | Merck & Co., Inc. | Enantioselective bioreduction using yeast |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3697M (en) * | 1963-05-27 | 1965-11-22 | Ici Ltd | Medicines based on novel heterocyclic compounds for the treatment of coronary artery disease. |
| NL131192C (en) * | 1965-06-16 | |||
| DE2325633A1 (en) * | 1973-05-21 | 1974-12-12 | Boehringer Sohn Ingelheim | PIPERAZINE DERIVATIVES |
-
1980
- 1980-11-24 ES ES497763A patent/ES497763A0/en active Granted
-
1981
- 1981-11-18 IT IT25157/81A patent/IT1194116B/en active
- 1981-11-23 DE DE19813146373 patent/DE3146373A1/en not_active Withdrawn
- 1981-11-24 JP JP56188271A patent/JPS57131784A/en active Pending
- 1981-11-24 FR FR8121936A patent/FR2494584A1/en active Granted
- 1981-11-24 NL NL8105310A patent/NL8105310A/en not_active Application Discontinuation
- 1981-11-24 BE BE0/206637A patent/BE891229A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS57131784A (en) | 1982-08-14 |
| FR2494584A1 (en) | 1982-05-28 |
| FR2494584B1 (en) | 1985-04-19 |
| BE891229A (en) | 1982-03-16 |
| ES497763A0 (en) | 1981-12-16 |
| IT1194116B (en) | 1988-09-14 |
| IT8125157A0 (en) | 1981-11-18 |
| DE3146373A1 (en) | 1982-12-02 |
| NL8105310A (en) | 1982-06-16 |
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