ES537257A0 - Un procedimiento de inmunoensayo - Google Patents

Un procedimiento de inmunoensayo

Info

Publication number: ES537257A0
Authority: ES; Spain
Prior art keywords: assay procedure; immuno assay; immuno; procedure; assay
Prior art date: 1982-04-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES537257A

Other languages

English (en)

Other versions

ES8606655A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Hybritech Inc

Original Assignee

Hybritech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-04-12

Filing date

1984-10-31

Publication date

1986-04-01

1984-10-31 Application filed by Hybritech Inc filed Critical Hybritech Inc

1986-04-01 Publication of ES537257A0 publication Critical patent/ES537257A0/es

1986-04-01 Publication of ES8606655A1 publication Critical patent/ES8606655A1/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1084—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being a hybrid immunoglobulin
- A61K51/109—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being a hybrid immunoglobulin immunoglobulins having two or more different antigen-binding sites or multifunctional antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo

Landscapes

Health & Medical Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biophysics (AREA)
Pharmacology & Pharmacy (AREA)
Optics & Photonics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Epidemiology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Physics & Mathematics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)

ES537257A 1982-04-12 1984-10-31 Un procedimiento de inmunoensayo Expired ES8606655A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US36778482A	1982-04-12	1982-04-12

Publications (2)

Publication Number	Publication Date
ES537257A0 true ES537257A0 (es)	1986-04-01
ES8606655A1 ES8606655A1 (es)	1986-04-01

Family

ID=23448582

Family Applications (7)

Application Number	Title	Priority Date	Filing Date
ES521370A Expired ES8504461A1 (es)	1982-04-12	1983-04-11	Un procedimiento para obtener un polidoma.
ES527963A Expired ES8503441A1 (es)	1982-04-12	1983-12-12	Un procedimiento de inmunoensayo
ES533930A Expired ES8603080A1 (es)	1982-04-12	1984-07-02	Un procedimiento para obtener un polidoma
ES533931A Granted ES533931A0 (es)	1982-04-12	1984-07-02	Un procedimiento para obtener un polidoma
ES537257A Expired ES8606655A1 (es)	1982-04-12	1984-10-31	Un procedimiento de inmunoensayo
ES538727A Expired ES8604424A1 (es)	1982-04-12	1984-12-18	Un procedimiento para obtener un hibridoma selectivamente destructible (como divisional de la solicitud de patente de invencion num 521370 presentada el 11 de abril de 1983
ES545247A Expired ES8607386A1 (es)	1982-04-12	1985-07-16	Un procedimiento para obtener un polidoma

Family Applications Before (4)

Application Number	Title	Priority Date	Filing Date
ES521370A Expired ES8504461A1 (es)	1982-04-12	1983-04-11	Un procedimiento para obtener un polidoma.
ES527963A Expired ES8503441A1 (es)	1982-04-12	1983-12-12	Un procedimiento de inmunoensayo
ES533930A Expired ES8603080A1 (es)	1982-04-12	1984-07-02	Un procedimiento para obtener un polidoma
ES533931A Granted ES533931A0 (es)	1982-04-12	1984-07-02	Un procedimiento para obtener un polidoma

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
ES538727A Expired ES8604424A1 (es)	1982-04-12	1984-12-18	Un procedimiento para obtener un hibridoma selectivamente destructible (como divisional de la solicitud de patente de invencion num 521370 presentada el 11 de abril de 1983
ES545247A Expired ES8607386A1 (es)	1982-04-12	1985-07-16	Un procedimiento para obtener un polidoma

Country Status (11)

Country	Link
EP (1)	EP0105360A4 (es)
JP (2)	JPH0753119B2 (es)
AT (1)	AT394577B (es)
AU (1)	AU550486B2 (es)
CA (1)	CA1213229A (es)
CH (1)	CH672796A5 (es)
ES (7)	ES8504461A1 (es)
FI (2)	FI900212A0 (es)
GB (4)	GB2128631B (es)
IT (1)	IT1219778B (es)
WO (1)	WO1983003679A1 (es)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3177776B2 (ja) *	1988-09-27	2001-06-18	武田薬品工業株式会社	ハイブリッドモノクローナル抗体，抗体産生ポリドーマおよび抗体含有薬剤
US5292668A (en) *	1981-12-21	1994-03-08	Boston Biomedical Research Institute, Inc.	Bispecific antibody determinants
IL70686A (en) *	1983-01-20	1988-07-31	Suntory Ltd	Mutant tumor cell lines for use in the preparation of hybridomas and the hybridomas obtained therefrom
GB2148299B (en) *	1983-09-01	1988-01-06	Hybritech Inc	Antibody compositions of therapeutic agents having an extended serum half-life
EP0467416A1 (en) *	1983-09-01	1992-01-22	Hybritech Incorporated	Antibody compositions of therapeutic agents having an extended serum half-life
DE3583278D1 (de) *	1984-04-23	1991-07-25	Boston Biomed Res Inst	Doppelspezifische antikoerper-determinanten.
NL8501219A (nl) *	1985-04-29	1986-11-17	Stichting Vrienden Van De Stic	Immunologisch complex, de bereiding en toepassing daarvan.
US5453269A (en) *	1986-04-14	1995-09-26	The General Hospital Corporation	Heterobifunctional antibodies having dual specificity for fibrin and thrombolylic agents and methods of use
EP0241907A3 (en)	1986-04-14	1989-09-13	The General Hospital Corporation	Heterobifunctional antibodies and method of use
FR2604092B1 (fr) *	1986-09-19	1990-04-13	Immunotech Sa	Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo
GB8626413D0 (en) *	1986-11-05	1986-12-03	Gilliland L K	Antibodies
GB8626412D0 (en) *	1986-11-05	1986-12-03	Clark M R	Antibodies
US5053226A (en) *	1987-07-15	1991-10-01	Board Of Regents, The University Of Texas System	Monoclonal antibodies binding platinum complexes
JP2755395B2 (ja) *	1987-09-23	1998-05-20	ブリストル―マイアーズスクイブコムパニー	Ｈｉｖ感染細胞に殺作用する抗体異種結合体
GB2218100A (en) *	1988-03-02	1989-11-08	Erling Sundrehagen	Conjugates for the detection and/or quantification of antigenic substances in body fluids
US4892824A (en) *	1988-03-15	1990-01-09	Synbiotics Corporation	Fast track method for producing monoclonal bi-specific immunoglobulins
US5372812A (en) *	1988-04-04	1994-12-13	The General Hospital Corporation	Composition and method for acceleration of clot lysis
US5582862A (en) *	1988-04-04	1996-12-10	General Hospital Corporation	Antibodies that bind to α2-antiplasmin crosslinked to fibrin which do not inhibit plasma α2-antiplasmin
JPH02196799A (ja) *	1988-04-08	1990-08-03	Agency Of Ind Science & Technol	抗ヒト癌蛋白複合体
US5851527A (en) *	1988-04-18	1998-12-22	Immunomedics, Inc.	Method for antibody targeting of therapeutic agents
IT1235349B (it) *	1988-12-23	1992-06-30	Biodata Spa	Saggio immunologico per determinazioni in fase omogenea
US5217713A (en) *	1988-12-27	1993-06-08	Takeda Chemical Industries, Ltd.	Cytotoxic bispecific monoclonal antibody, its production and use
CA2006408A1 (en) *	1988-12-27	1990-06-27	Susumu Iwasa	Bispecific monoclonal antibody, its production and use
WO1990012109A1 (en) *	1989-03-30	1990-10-18	Board Of Regents, The University Of Texas System	Monoclonal antibodies binding platinum complexes
FR2652004B1 (fr) *	1989-09-21	1994-10-28	Immunotech Partners	Nouveaux derives hydrophiles, application au diagnostic et a la therapeutique, kits diagnostiques ou therapeutiques et reactifs immunologiques.
CA2075927A1 (en) *	1990-02-16	1991-08-17	Victor A. Raso	Hybrid reagents capable of selectively releasing molecules into cells
TW212184B (es) *	1990-04-02	1993-09-01	Takeda Pharm Industry Co Ltd
JP3431140B2 (ja) *	1991-04-26	2003-07-28	サーフィス・アクティブ・リミテッド	抗体およびその使用方法
GB9316369D0 (en) *	1993-08-06	1993-09-22	Surface Active Ltd	Diagnostic method
US5541110A (en)	1994-05-17	1996-07-30	Bristol-Myers Squibb	Cloning and expression of a gene encoding bryodin 1 from Bryonia dioica
GB9421468D0 (en) *	1994-10-18	1994-12-07	Surface Active Ltd	Biosensor
JP2001502895A (ja) *	1996-09-20	2001-03-06	ザ・ジェネラル・ホスピタル・コーポレイション	アルファ―２―抗プラスミンに対するキメラ、ヒト化および一本鎖抗体
US20020132274A1 (en)	2001-01-17	2002-09-19	Nevalainen Marja T.	Diagnostic and monitorings methods for cancer
AU2003263964C1 (en)	2002-07-31	2010-08-19	Seagen Inc.	Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease
NZ547633A (en)	2003-11-06	2010-08-27	Seattle Genetics Inc	Monomethylvaline compounds capable of conjugation to ligands
HUE030786T2 (en)	2004-03-16	2017-06-28	Temple Univ - Of The Commonwealth System Of Higher Education	Substituted phenoxy and phenylthio derivatives for the treatment of proliferative disorders
US8288352B2 (en)	2004-11-12	2012-10-16	Seattle Genetics, Inc.	Auristatins having an aminobenzoic acid unit at the N terminus
ES2477765T3 (es)	2005-04-19	2014-07-17	Seattle Genetics, Inc.	Agentes de unión al anti-cd70 humanizado y usos de los mismos
WO2007011968A2 (en)	2005-07-18	2007-01-25	Seattle Genetics, Inc.	Beta-glucuronide-linker drug conjugates
US8455622B2 (en)	2006-12-01	2013-06-04	Seattle Genetics, Inc.	Variant target binding agents and uses thereof
NZ577933A (en)	2007-01-22	2011-12-22	Genentech Inc	Polyelectrolyte precipitation and purification of antibodies
CA2723197C (en)	2008-05-02	2017-09-19	Seattle Genetics, Inc.	Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation
WO2011133658A1 (en)	2010-04-22	2011-10-27	Boston Medical Center Corporation	Compositions and methods for targeting and delivering therapeutics into cells
US9353150B2 (en)	2012-12-04	2016-05-31	Massachusetts Institute Of Technology	Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment
TR201911139T4 (tr)	2013-03-15	2019-08-21	Zymeworks Inc	Sitotoksik ve anti-mitotik bileşikler ve bunları kullanmanın yöntemleri.
US10227407B2 (en)	2013-10-10	2019-03-12	Yukinari Kato	Anti-podoplanin antibody
EP3086815B1 (en)	2013-12-27	2022-02-09	Zymeworks Inc.	Sulfonamide-containing linkage systems for drug conjugates
SG11201702143PA (en)	2014-09-17	2017-04-27	Zymeworks Inc	Cytotoxic and anti-mitotic compounds, and methods of using the same
EP3165237B1 (en)	2015-11-03	2018-12-19	Industrial Technology Research Institute	Antibody-drug conjugate (adc) and method for forming the same
EP3433278A4 (en)	2016-03-25	2019-11-06	Seattle Genetics, Inc.	METHOD FOR THE PRODUCTION OF PEGYLATED ACTIVE LINKERS AND INTERMEDIATE PRODUCTS THEREOF
US10918627B2 (en)	2016-05-11	2021-02-16	Massachusetts Institute Of Technology	Convergent and enantioselective total synthesis of Communesin analogs
EP3600443A1 (en)	2017-03-24	2020-02-05	Seattle Genetics, Inc.	Process for the preparation of glucuronide drug-linkers and intermediates thereof
WO2018209239A1 (en)	2017-05-11	2018-11-15	Massachusetts Institute Of Technology	Potent agelastatin derivatives as modulators for cancer invasion and metastasis
US10640508B2 (en)	2017-10-13	2020-05-05	Massachusetts Institute Of Technology	Diazene directed modular synthesis of compounds with quaternary carbon centers
US10869888B2 (en)	2018-04-17	2020-12-22	Innovative Cellular Therapeutics CO., LTD.	Modified cell expansion and uses thereof
JP7156653B2 (ja)	2018-08-30	2022-10-19	イノベイティブセルラーセラピューティクスホールディングス，エルティディ	固形腫瘍を治療するためのキメラ抗原受容体細胞
US12240915B2 (en)	2018-08-30	2025-03-04	Innovative Cellular Therapeutics Holdings, Ltd.	Chimeric antigen receptor cells for treating solid tumor
MX2021013657A (es)	2019-05-10	2022-02-21	Takeda Pharmaceuticals Co	Conjugados de anticuerpo y farmaco.
TWI877278B (zh)	2019-12-30	2025-03-21	美商思進公司	以非海藻糖苷化抗－ｃｄ７０抗體治療癌症之方法
US12076343B2 (en)	2020-02-19	2024-09-03	Innovative Cellular Therapeutics Holdings, Ltd.	Engineered safety in cell therapy
US12043654B2 (en)	2020-06-02	2024-07-23	Innovative Cellular Therapeutics Holdings, Ltd.	Anti-GCC antibody and CAR thereof for treating digestive system cancer
EP4240488A1 (en)	2020-11-09	2023-09-13	Takeda Pharmaceutical Company Limited	Antibody drug conjugates
US12030888B2 (en)	2021-02-24	2024-07-09	Massachusetts Institute Of Technology	Himastatin derivatives, and processes of preparation thereof, and uses thereof
CA3221281A1 (en)	2021-06-29	2023-01-05	Seagen Inc.	Methods of treating cancer with a combination of a nonfucosylated anti-cd70 antibody and a cd47 antagonist

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4130634A (en) *	1974-03-15	1978-12-19	University Of Illinois Foundation	Method for detecting and quantifying antigens
US4331647A (en) *	1980-03-03	1982-05-25	Goldenberg Milton David	Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
US4376110A (en) *	1980-08-04	1983-03-08	Hybritech, Incorporated	Immunometric assays using monoclonal antibodies
US4474893A (en) *	1981-07-01	1984-10-02	The University of Texas System Cancer Center	Recombinant monoclonal antibodies

1983
- 1983-04-11 ES ES521370A patent/ES8504461A1/es not_active Expired
- 1983-04-11 CA CA000425558A patent/CA1213229A/en not_active Expired
- 1983-04-12 WO PCT/US1983/000525 patent/WO1983003679A1/en not_active Ceased
- 1983-04-12 EP EP19830901672 patent/EP0105360A4/en not_active Ceased
- 1983-04-12 GB GB08332646A patent/GB2128631B/en not_active Expired
- 1983-04-12 IT IT20548/83A patent/IT1219778B/it active
- 1983-04-12 FI FI900212A patent/FI900212A0/fi not_active Application Discontinuation
- 1983-04-12 FI FI834529A patent/FI834529L/fi not_active Application Discontinuation
- 1983-04-12 AT AT0901883A patent/AT394577B/de not_active IP Right Cessation
- 1983-04-12 AU AU15559/83A patent/AU550486B2/en not_active Expired
- 1983-04-12 CH CH6700/83A patent/CH672796A5/de not_active IP Right Cessation
- 1983-12-12 ES ES527963A patent/ES8503441A1/es not_active Expired
1984
- 1984-07-02 ES ES533930A patent/ES8603080A1/es not_active Expired
- 1984-07-02 ES ES533931A patent/ES533931A0/es active Granted
- 1984-10-31 ES ES537257A patent/ES8606655A1/es not_active Expired
- 1984-12-18 ES ES538727A patent/ES8604424A1/es not_active Expired
1985
- 1985-07-16 ES ES545247A patent/ES8607386A1/es not_active Expired
- 1985-12-09 GB GB08530309A patent/GB2169921B/en not_active Expired
- 1985-12-09 GB GB08530308A patent/GB2168998B/en not_active Expired
- 1985-12-09 GB GB08530310A patent/GB2167086B/en not_active Expired
1987
- 1987-01-05 JP JP62000342A patent/JPH0753119B2/ja not_active Expired - Lifetime
1994
- 1994-02-10 JP JP6016728A patent/JP2562002B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES545247A0 (es)	1986-05-16
FI900212A7 (fi)	1990-01-15
FI834529A7 (fi)	1983-12-09
ES533930A0 (es)	1985-12-01
JPH0753600A (ja)	1995-02-28
AU1555983A (en)	1983-11-04
ES8604424A1 (es)	1986-02-01
AT394577B (de)	1992-05-11
ES521370A0 (es)	1985-04-16
CA1213229A (en)	1986-10-28
ATA901883A (de)	1991-10-15
GB2128631B (en)	1987-02-25
EP0105360A1 (en)	1984-04-18
EP0105360A4 (en)	1986-07-08
ES8603080A1 (es)	1985-12-01
WO1983003679A1 (en)	1983-10-27
ES8506091A1 (es)	1985-06-16
GB2128631A (en)	1984-05-02
ES533931A0 (es)	1985-06-16
IT1219778B (it)	1990-05-24
ES538727A0 (es)	1986-02-01
ES8606655A1 (es)	1986-04-01
JP2562002B2 (ja)	1996-12-11
GB2167086A (en)	1986-05-21
ES527963A0 (es)	1985-02-16
GB8530308D0 (en)	1986-01-22
AU550486B2 (en)	1986-03-20
FI834529A0 (fi)	1983-12-09
GB2167086B (en)	1987-03-04
GB8530309D0 (en)	1986-01-22
ES8503441A1 (es)	1985-02-16
GB2169921B (en)	1987-03-04
ES8504461A1 (es)	1985-04-16
IT8320548A0 (it)	1983-04-12
FI900212A0 (fi)	1990-01-15
GB2169921A (en)	1986-07-23
GB2168998B (en)	1987-03-04
ES8607386A1 (es)	1986-05-16
CH672796A5 (es)	1989-12-29
FI834529L (fi)	1983-12-09
JPH0753119B2 (ja)	1995-06-07
GB8332646D0 (en)	1984-01-11
JPS6312276A (ja)	1988-01-19
GB8530310D0 (en)	1986-01-22
GB2168998A (en)	1986-07-02

Publication	Publication Date	Title
ES537257A0 (es)	1986-04-01	Un procedimiento de inmunoensayo
BR8300936A (pt)	1983-11-16	Pinca de ligacao
DK52483D0 (da)	1983-02-08	Immunoassay
DK320783D0 (da)	1983-07-12	Klaebemiddel
FI832726A7 (fi)	1984-02-04	Halogeneringsfoerfarande
DK104283A (da)	1983-09-02	Humant immuninterferon
ES524460A0 (es)	1985-11-01	Un metodo de inmunoensayo.
DK606183D0 (da)	1983-12-29	Stikforbindelse
FI840305A0 (fi)	1984-01-25	Demolerande produkt
DK513482A (da)	1984-01-15	Stoedaccelerator
DK453283D0 (da)	1983-09-30	Forbindelser
ES527737A0 (es)	1984-08-01	Procedimiento de preparacion de dinucleosidos-monofosfatos
ES525995A0 (es)	1985-04-16	Procedimiento de obtencion de piridopirimidinonas
ES519779A0 (es)	1983-11-16	Prensa-recogedora de sarmientos.
ES292964Y (es)	1987-04-16	Perpiano de construccion
FI832971L (fi)	1984-04-21	Under vaermepaoverkan krympande foerbindelsemuff
FR2537351B1 (fr)	1988-04-15	Reglette de raccordement
KR840002462U (ko)	1984-06-27	리시이버
ATA286582A (de)	1984-04-15	Testgeschoss
BR8205287A (pt)	1984-04-17	Acelerador de percussor
BR8202114A (pt)	1983-11-16	Cacada de bufalos
BR8202758A (pt)	1983-12-20	Amolador de facas
AR227230A1 (es)	1982-09-30	Un corpino mejorado
RO83994A2 (ro)	1984-07-17	Ciocan de abataj
FI821363A0 (fi)	1982-04-20	Test foer glykosilerade hemoglobiner

Legal Events

Date	Code	Title	Description
1997-05-01	FD1A	Patent lapsed	Effective date: 19970401