[go: up one dir, main page]

ES437407A1 - Preparation of 2-nitroindan-1,3-diones - Google Patents

Preparation of 2-nitroindan-1,3-diones

Info

Publication number
ES437407A1
ES437407A1 ES437407A ES437407A ES437407A1 ES 437407 A1 ES437407 A1 ES 437407A1 ES 437407 A ES437407 A ES 437407A ES 437407 A ES437407 A ES 437407A ES 437407 A1 ES437407 A1 ES 437407A1
Authority
ES
Spain
Prior art keywords
formula
nitroindan
preparation
pharmaceutically acceptable
diones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES437407A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES437407A1 publication Critical patent/ES437407A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A process for the preparation of 2-nitroindan-l, 3-dione derivatives of formula (I) and pharmaceutically acceptable salts thereof: ** (See formula) ** where R5 and R6 are the same or different and represent hydrogen, alkyl or alkoxy of 1 to 3 carbon atoms or linked represent the residues of a carbocyclic ring, the procedure of which is to react a compound of formula (II): ** (See formula) ** where R5 and R6 are those defined in relation to formula (I), with a tertiary base and then converting the product into a pharmaceutically acceptable salt. (Machine-translation by Google Translate, not legally binding)
ES437407A 1974-05-03 1975-05-02 Preparation of 2-nitroindan-1,3-diones Expired ES437407A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1947774A GB1460045A (en) 1974-05-03 1974-05-03 Preparation of 2-nitroindan-1,3-diones

Publications (1)

Publication Number Publication Date
ES437407A1 true ES437407A1 (en) 1977-04-01

Family

ID=10130020

Family Applications (1)

Application Number Title Priority Date Filing Date
ES437407A Expired ES437407A1 (en) 1974-05-03 1975-05-02 Preparation of 2-nitroindan-1,3-diones

Country Status (7)

Country Link
JP (1) JPS50151854A (en)
AT (1) AT337683B (en)
CH (1) CH596137A5 (en)
DK (1) DK183475A (en)
ES (1) ES437407A1 (en)
GB (1) GB1460045A (en)
SE (1) SE7504849L (en)

Also Published As

Publication number Publication date
DK183475A (en) 1975-11-04
SE7504849L (en) 1975-11-04
JPS50151854A (en) 1975-12-06
AT337683B (en) 1977-07-11
CH596137A5 (en) 1978-02-28
GB1460045A (en) 1976-12-31
ATA338575A (en) 1976-11-15

Similar Documents

Publication Publication Date Title
ES462062A1 (en) Tetrahydroisoquinoline basic ethers and pharmaceutical compositions and methods employing them
ES437407A1 (en) Preparation of 2-nitroindan-1,3-diones
ES446581A1 (en) Biphenylhydroxypropionic acid derivatives
ES464045A1 (en) A PROCEDURE FOR THE PRODUCTION OF A GAMMA-PIRONA.
ES400841A1 (en) 2-hydroxybenzophenones
ES417396A1 (en) A procedure for the production of a pharmaceutical composition. (Machine-translation by Google Translate, not legally binding)
ES438704A1 (en) Ergot peptide alkaloids
ES384802A1 (en) 5-hydroxycoumarin derivatives
ES423817A1 (en) D-2-substituted-6-alkyl-8-substituted ergolines and process for preparing same
ES437408A1 (en) A procedure for the preparation of new derivatives of indan 1, 3-diona. (Machine-translation by Google Translate, not legally binding)
ES429691A1 (en) Preparation of p-isobutyl hydratropic acid and intermediates therefor
ES440282A1 (en) Diphenyl-butylpiperidines
ES327203A1 (en) Procedure for the production of benzo-diacepin-8-ona derivatives. (Machine-translation by Google Translate, not legally binding)
ES428707A1 (en) Procedure for preparation of new derivatives of 7h-indolizino (5, 6, 7-ij), isoquinolein. (Machine-translation by Google Translate, not legally binding)
ES436499A1 (en) Oxazolidines and conversion to propanolamines
ES441029A1 (en) PROCEDURE FOR THE PREPARATION OF A NEW DERIVATIVE OF ACETYLSALYTIC ACID
ES425405A1 (en) Procedure for preparing new derivatives of dibenzo (a, d) ciclohepteno. (Machine-translation by Google Translate, not legally binding)
ES434922A1 (en) 2-halo-indan-1,3-diones and their use in preparing 2-nitro-indan-1,3 diones
ES425030A1 (en) Procedure for preparing piperazine derivatives. (Machine-translation by Google Translate, not legally binding)
ES320083A1 (en) Procedure for the preparation of derivatives of difenylamine. (Machine-translation by Google Translate, not legally binding)
ES428696A1 (en) Procedure for preparation of new derivatives of 7h-indolizino (5, 6, 7-ij), isoquinolein. (Machine-translation by Google Translate, not legally binding)
ES431553A1 (en) 3-hydroxy-2-4-hydroxy-1-alkylnyl-5-oxo-1-cylopent-ene-1-hep tanoic acids and derivatives thereof
ES459400A1 (en) 6,11-dihydrodibenzo - thiepin - 11 - ones methods of preparation compositions and uses thereof
ES444005A2 (en) Salts of 2-alkylthiazole-5-methanol derivatives
ES428697A1 (en) Procedure for the preparation of new derivatives of 7h-indolyzin (5,6,7-ij) isoquinolein. (Machine-translation by Google Translate, not legally binding)