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ES437408A1 - A procedure for the preparation of new derivatives of indan 1, 3-diona. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of new derivatives of indan 1, 3-diona. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES437408A1
ES437408A1 ES437408A ES437408A ES437408A1 ES 437408 A1 ES437408 A1 ES 437408A1 ES 437408 A ES437408 A ES 437408A ES 437408 A ES437408 A ES 437408A ES 437408 A1 ES437408 A1 ES 437408A1
Authority
ES
Spain
Prior art keywords
formula
translation
preparation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES437408A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB19721/74A external-priority patent/GB1509904A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES437408A1 publication Critical patent/ES437408A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/665—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
    • C07C49/67—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having two rings, e.g. tetralones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/24—Quinones containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/32—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • C07C65/05—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring o-Hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
    • C07D311/46—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)

Abstract

A process for the preparation of new derivatives of indu-1,3-dione of formula (I) or a pharmaceutically acceptable salt thereof: **(See formula)** where R1, R2, R3 and R4 are each a hydrogen or halogen atom or an alkyl or alkoxy group or any two of the R1, R2, R3 and R4 groups taken together with or the carbon atoms Linked together, they complete a substituted or unsubstituted carbocyclic ring and X represents a bond, provided that the groups R1, R2, R3 and R4 are not all hydrogen atoms; whose process is characterized in that, (a) a compound of formula (V) is reacted with a base: **(See formula)** where R1, R2, R3 and R4 are as defined above and (b), the thus formed compound of formula (I) is converted into a salt thereof. (Machine-translation by Google Translate, not legally binding)
ES437408A 1974-05-04 1975-05-02 A procedure for the preparation of new derivatives of indan 1, 3-diona. (Machine-translation by Google Translate, not legally binding) Expired ES437408A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB19721/74A GB1509904A (en) 1974-05-04 1974-05-04 Nitriles derived from indane-1,3-dione and coumarin
GB4811574 1974-11-07

Publications (1)

Publication Number Publication Date
ES437408A1 true ES437408A1 (en) 1977-08-01

Family

ID=26254216

Family Applications (3)

Application Number Title Priority Date Filing Date
ES437408A Expired ES437408A1 (en) 1974-05-04 1975-05-02 A procedure for the preparation of new derivatives of indan 1, 3-diona. (Machine-translation by Google Translate, not legally binding)
ES454326A Expired ES454326A1 (en) 1974-05-04 1976-12-16 A procedure for the preparation of new derivatives of cumarina. (Machine-translation by Google Translate, not legally binding)
ES454325A Expired ES454325A1 (en) 1974-05-04 1976-12-16 A procedure for the preparation of new derivatives of indan-1,3-diona. (Machine-translation by Google Translate, not legally binding)

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES454326A Expired ES454326A1 (en) 1974-05-04 1976-12-16 A procedure for the preparation of new derivatives of cumarina. (Machine-translation by Google Translate, not legally binding)
ES454325A Expired ES454325A1 (en) 1974-05-04 1976-12-16 A procedure for the preparation of new derivatives of indan-1,3-diona. (Machine-translation by Google Translate, not legally binding)

Country Status (7)

Country Link
JP (1) JPS50160254A (en)
DE (1) DE2519713A1 (en)
DK (1) DK193675A (en)
ES (3) ES437408A1 (en)
FR (2) FR2269334A1 (en)
NL (1) NL7505201A (en)
SE (1) SE7505038L (en)

Also Published As

Publication number Publication date
DK193675A (en) 1975-11-05
ES454326A1 (en) 1977-12-16
FR2269334B1 (en) 1978-10-06
SE7505038L (en) 1975-12-19
DE2519713A1 (en) 1975-11-20
FR2269334A1 (en) 1975-11-28
ES454325A1 (en) 1977-12-16
AU8079175A (en) 1976-11-04
JPS50160254A (en) 1975-12-25
FR2282876B1 (en) 1980-05-16
FR2282876A1 (en) 1976-03-26
NL7505201A (en) 1975-11-06

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