ES428696A1 - Procedure for preparation of new derivatives of 7h-indolizino (5, 6, 7-ij), isoquinolein. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for preparation of new derivatives of 7h-indolizino (5, 6, 7-ij), isoquinolein. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES428696A1 ES428696A1 ES428696A ES428696A ES428696A1 ES 428696 A1 ES428696 A1 ES 428696A1 ES 428696 A ES428696 A ES 428696A ES 428696 A ES428696 A ES 428696A ES 428696 A1 ES428696 A1 ES 428696A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- indolizino
- radical
- alkyl part
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical compound O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- LXGVPCGSNKMLRI-UHFFFAOYSA-N 2,10-diazatetracyclo[7.6.1.05,16.010,14]hexadeca-1,3,5(16),6,8,11,13-heptaene Chemical class C1=NC(CC=2N3C=CC=2)=C2C3=CC=CC2=C1 LXGVPCGSNKMLRI-UHFFFAOYSA-N 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Procedure for the preparation of new derivatives of 7H-indolizino [5, 6, 7-ij] isoquinoline, of general formula: **(See formula)** in which: R represents a hydrogen or halogen atom or an alkyloxy radical whose alkyl part contains 1 to 4 carbon atoms, and represents a hydrogen atom, an alkyl radical containing 1 to 4 carbon atoms (replaced by a carboxy radical, alkyloxycarbonyl whose alkyl part contains 1 to 7 carbon atoms or carbamoyl), a phenylalkyl radical (whose alkyl part containing 1 to 4 carbon atoms is replaced by a carboxy radical, alkyloxycarbonyl whose alkyl part contains 1 to 4 carbon atoms carbon or carbamoyl), as well as their metal salts and addition salts with the nitrogenous bases when they exist, characterized in that: a product of the general formula is reacted: H2N-O-R1 in which R1 is defined as above, on a 7H-indolizino [5, 6, 7-ij] isoquinoline-7 of general formula: **(See formula)** in which R is defined as above -and then, eventually, the product is transformed- obtained into a metal salt or an addition salt with a nitrogen base. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7327649A FR2244515A1 (en) | 1973-07-27 | 1973-07-27 | 7H-Indolizino (5,6,7-i,j)-isoquinolines - as antibilharzial, anthelmintic and antimicrobial agents |
| FR7418808A FR2272668A2 (en) | 1974-05-30 | 1974-05-30 | 7H-Indolizino (5,6,7-i,j)-isoquinolines - as antibilharzial, anthelmintic and antimicrobial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES428696A1 true ES428696A1 (en) | 1977-01-01 |
Family
ID=26217864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES428696A Expired ES428696A1 (en) | 1973-07-27 | 1974-07-27 | Procedure for preparation of new derivatives of 7h-indolizino (5, 6, 7-ij), isoquinolein. (Machine-translation by Google Translate, not legally binding) |
Country Status (3)
| Country | Link |
|---|---|
| AR (1) | AR204793A1 (en) |
| CH (1) | CH592665A5 (en) |
| ES (1) | ES428696A1 (en) |
-
1974
- 1974-07-26 CH CH164477A patent/CH592665A5/en not_active IP Right Cessation
- 1974-07-27 ES ES428696A patent/ES428696A1/en not_active Expired
-
1975
- 1975-01-01 AR AR26124675A patent/AR204793A1/en active
Also Published As
| Publication number | Publication date |
|---|---|
| AR204793A1 (en) | 1976-02-27 |
| CH592665A5 (en) | 1977-10-31 |
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