[go: up one dir, main page]

ES414289A1 - Derivatives of delta 1-pyrroline their method of preparation and their applications - Google Patents

Derivatives of delta 1-pyrroline their method of preparation and their applications

Info

Publication number
ES414289A1
ES414289A1 ES414289A ES414289A ES414289A1 ES 414289 A1 ES414289 A1 ES 414289A1 ES 414289 A ES414289 A ES 414289A ES 414289 A ES414289 A ES 414289A ES 414289 A1 ES414289 A1 ES 414289A1
Authority
ES
Spain
Prior art keywords
formula
radical
alcoholic
pyrroline
atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES414289A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Jacques Logeais SA
Original Assignee
Laboratoires Jacques Logeais SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Jacques Logeais SA filed Critical Laboratoires Jacques Logeais SA
Publication of ES414289A1 publication Critical patent/ES414289A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Preparation procedure for < 1-pyrroline derivatives of the general formula **(See formula)** in which R1 taken separately represents a hydrogen atom, an alcoholic radical, phenylalkyl, phenyl, a dialkoxylaminoalcoyl radical or a -NH-C-O-R4 radical, where R4 is an alcoholic radical; and R2 taken separately represents a hydrogen atom; or R1 and R2 we take together form with the nitrogen atom to which they are attached a heterocyclic nucleus that has from 5 to 7 links that can carry as second heteroatom an oxygen atom or a nitrogen atom that in turn can carry a radical alcoholic R3 represents a hydrogen or halogen atom, an alcohol or alkoxy radical and n is equal to 0, 1 or 2; and its addition salts with acids, characterized in that it is reacted with a pyrrolidinone-2 of the formula **(See formula)** where R3 and n have the meanings indicated above, triethyloxonium tetrafluoroborate of the formula + O (C2H5) 3 -BF4 in an inert solvent and then reacted with the Δ 1-pyrroline of the formula **(See formula)** thus obtained, an amine of the formula HNR1R2, wherein R1 and R2 have the meanings indicated above, thereby obtaining the desired derivative of formula (I). (Machine-translation by Google Translate, not legally binding)
ES414289A 1972-05-03 1973-05-02 Derivatives of delta 1-pyrroline their method of preparation and their applications Expired ES414289A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7215636A FR2186236B1 (en) 1972-05-03 1972-05-03

Publications (1)

Publication Number Publication Date
ES414289A1 true ES414289A1 (en) 1976-01-16

Family

ID=9097884

Family Applications (1)

Application Number Title Priority Date Filing Date
ES414289A Expired ES414289A1 (en) 1972-05-03 1973-05-02 Derivatives of delta 1-pyrroline their method of preparation and their applications

Country Status (7)

Country Link
JP (1) JPS4947366A (en)
BE (1) BE798779A (en)
CH (1) CH566981A5 (en)
DE (1) DE2321950A1 (en)
ES (1) ES414289A1 (en)
FR (1) FR2186236B1 (en)
GB (1) GB1367598A (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50140080A (en) * 1974-04-25 1975-11-10
DE3149776C2 (en) * 1981-12-16 1985-11-14 Daimler-Benz Ag, 7000 Stuttgart Valve guide arrangement for a poppet valve controlling the connection of a main exhaust line of an internal combustion engine with a secondary exhaust line
FR2540109B1 (en) * 1983-01-28 1985-08-30 Logeais Labor Jacques IMINO-2 PYRROLIDINES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATIONS
JPS6016989A (en) * 1983-07-06 1985-01-28 Shionogi & Co Ltd Oxo-saturated heterocyclic carbon amide cephem compound
JPS6222757A (en) * 1985-07-22 1987-01-30 Daicel Chem Ind Ltd Substituted anilino-2-pyrroline derivative
EP0561961A1 (en) * 1990-12-13 1993-09-29 E.I. Du Pont De Nemours And Company Novel heterocyclic amidines and guanidines as plant fungicides
KR100342275B1 (en) 1993-10-21 2002-12-05 지.디. 썰 엘엘씨 Amidino derivatives useful as nitric oxide synthase inhibitors
EP0821674B1 (en) * 1995-04-20 2003-08-06 G.D. SEARLE &amp; CO. Cyclic amidino agents useful as nitric oxide synthase inhibitors
US5945408A (en) * 1996-03-06 1999-08-31 G.D. Searle & Co. Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors
US5981556A (en) * 1997-07-22 1999-11-09 G.D. Searle & Co. 1,3-diazolino and 1,3-diazolidino heterocycles as useful nitric oxide synthase inhibitors
CA2333691A1 (en) 1998-06-10 1999-12-16 G.D. Searle & Co. Heterobicyclic and tricyclic nitric oxide synthase inhibitors
SE520050C2 (en) 2000-03-30 2003-05-13 Bertil Johansson Composite projectile and cartridge containing such projectile
US6344473B1 (en) 2000-08-07 2002-02-05 G.D. Searle & Co. Imidazoles useful as nitric oxide synthase inhibitors
LV14346B (en) * 2009-11-05 2011-07-20 Grindeks, A/S 2- (4-Phenyl-5-methyl-2-oxopyrrolidin-1-yl) -acetam &imacr; da 4R, 5S-enantiomer &emacr; ar nootropic activity &

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3632604A (en) * 1970-04-09 1972-01-04 Sandoz Ag 2-substituted-4-phenyl and substituted phenyl-1-pyrrolines

Also Published As

Publication number Publication date
GB1367598A (en) 1974-09-18
FR2186236B1 (en) 1975-08-01
DE2321950A1 (en) 1973-11-15
BE798779A (en) 1973-08-16
FR2186236A1 (en) 1974-01-11
JPS4947366A (en) 1974-05-08
CH566981A5 (en) 1975-09-30

Similar Documents

Publication Publication Date Title
ES414289A1 (en) Derivatives of delta 1-pyrroline their method of preparation and their applications
ES410730A1 (en) 1-aroylalkyl-4-diphenylmethyl piperidines
SE7712630L (en) PROCEDURE FOR THE PREPARATION OF O-ALKYLATED HYDROXYLAMINES
ES411380A1 (en) Pyrazoline compounds having insecticidal activity
ES260933A1 (en) 3-(3-indolyl) pyrrolidines
ES417700A1 (en) Basically substituted benzene-1,3-disulfonamides and process for their manufacture
ES425576A1 (en) Pyrazoles and process for their preparation
ES433132A1 (en) Derivatives of 1-phenoxy-3-aminopropan-2-ol and processes for their preparation
ES413960A1 (en) Manufacture of novel propylene-diamine derivative
ES417471A1 (en) Acylated n6-aralkyl-adenosine derivatives
ES422318A1 (en) Pigments compositions containing azoarylamides
ES446444A1 (en) Process for the preparation of carbonyl alpha-perfluoro derivatives
NO844778L (en) PROCEDURE FOR PREPARING 2-HYDROXY-PROPIOPHENOMIC DERIVATIVES
ES444036A1 (en) Process for the preparation of 2-2-thienyl-ethylamine and derivatives thereof
ES371373A1 (en) Procedure for the obtaining of substitute 4-oxo-3-amino-3,4-dihydrotean (3,2-d) pyrimidine derivatives. (Machine-translation by Google Translate, not legally binding)
ES394484A1 (en) PROCEDURE FOR THE PREPARATION OF 1,4-BENZO-DIAZEPINIC DERIVATIVES.
ES388696A1 (en) Cyano-and trifluoromethyl-substituted 6-nitroanilines
ES416973A1 (en) Procedure for the preparation of derivatives of 1,8-naftiridina. (Machine-translation by Google Translate, not legally binding)
ES411447A1 (en) Acrylic acid derivatives
ES406767A1 (en) Procedure for the preparation of new indol derivatives. (Machine-translation by Google Translate, not legally binding)
ES444644A1 (en) Process for the preparation of thieno-pyridine derivatives
ES404601A1 (en) A PROCEDURE FOR THE PRODUCTION OF PENICILLIN-NA ESTERS OR PENICILLIN SULFOXIDE.
ES386326A1 (en) Benzene diazonium compounds and diazotype material containing the same
ES398973A1 (en) PROCEDURE FOR OBTAINING A DERIVATIVE OF RIFAMICI-NA SV.
ES394803A1 (en) PROCEDURE FOR OBTAINING LEUCAURAMI-NA DERIVATIVES.