EE05174B1 - Kemokiini mutandi kasutamine farmatseutilise kompositsiooni valmistamiseks, mis on ette nhtud hulgiskleroosi ja teiste meliinikaotusega seotud haiguste raviks - Google Patents
Kemokiini mutandi kasutamine farmatseutilise kompositsiooni valmistamiseks, mis on ette nhtud hulgiskleroosi ja teiste meliinikaotusega seotud haiguste raviksInfo
- Publication number
- EE05174B1 EE05174B1 EEP200300139A EEP200300139A EE05174B1 EE 05174 B1 EE05174 B1 EE 05174B1 EE P200300139 A EEP200300139 A EE P200300139A EE P200300139 A EEP200300139 A EE P200300139A EE 05174 B1 EE05174 B1 EE 05174B1
- Authority
- EE
- Estonia
- Prior art keywords
- preparation
- treatment
- pharmaceutical composition
- multiple sclerosis
- loss diseases
- Prior art date
Links
- 102000019034 Chemokines Human genes 0.000 title 1
- 108010012236 Chemokines Proteins 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 201000006417 multiple sclerosis Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00121665 | 2000-10-04 | ||
| PCT/EP2001/011428 WO2002028419A2 (en) | 2000-10-04 | 2001-10-03 | Chemokine mutants in the treatment of multiple sclerosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE200300139A EE200300139A (et) | 2003-06-16 |
| EE05174B1 true EE05174B1 (et) | 2009-06-15 |
Family
ID=8170011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200300139A EE05174B1 (et) | 2000-10-04 | 2001-10-03 | Kemokiini mutandi kasutamine farmatseutilise kompositsiooni valmistamiseks, mis on ette nhtud hulgiskleroosi ja teiste meliinikaotusega seotud haiguste raviks |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US7402303B2 (xx) |
| EP (1) | EP1326628B1 (xx) |
| JP (1) | JP3908165B2 (xx) |
| KR (1) | KR100837898B1 (xx) |
| CN (1) | CN1285381C (xx) |
| AR (1) | AR030854A1 (xx) |
| AT (1) | ATE265222T1 (xx) |
| AU (2) | AU2002215919B2 (xx) |
| BG (1) | BG66137B1 (xx) |
| BR (1) | BR0114407A (xx) |
| CA (1) | CA2423616C (xx) |
| CZ (1) | CZ303409B6 (xx) |
| DE (1) | DE60103078T2 (xx) |
| DK (1) | DK1326628T3 (xx) |
| EA (1) | EA006137B1 (xx) |
| EE (1) | EE05174B1 (xx) |
| ES (1) | ES2217199T3 (xx) |
| HR (1) | HRP20030215B1 (xx) |
| HU (1) | HUP0302194A3 (xx) |
| IL (2) | IL155178A0 (xx) |
| MX (1) | MXPA03003008A (xx) |
| NO (1) | NO330278B1 (xx) |
| PL (1) | PL204231B1 (xx) |
| PT (1) | PT1326628E (xx) |
| RS (1) | RS50738B (xx) |
| SI (1) | SI1326628T1 (xx) |
| SK (1) | SK287523B6 (xx) |
| UA (1) | UA77950C2 (xx) |
| WO (1) | WO2002028419A2 (xx) |
| ZA (1) | ZA200302315B (xx) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003051921A1 (en) | 2001-12-17 | 2003-06-26 | Applied Research Systems Ars Holding N.V. | Chemokine mutants acting as chemokine antagonists |
| US7335350B2 (en) | 2002-04-04 | 2008-02-26 | Laboratoires Serono Sa | Chemokines mutants having improved oral bioavailability |
| AU2003302755B2 (en) * | 2002-12-23 | 2009-01-08 | Laboratoires Serono Sa | Use of CC-chemokine mutants against liver diseases |
| WO2005040210A2 (en) * | 2003-10-22 | 2005-05-06 | Applied Research Systems Ars Holding N.V. | Novel cxcl8 antagonists |
| AT412785B (de) * | 2003-12-04 | 2005-07-25 | Kungl Andreas J Dr | Gag-bindungsproteine |
| ATE322506T1 (de) * | 2004-01-19 | 2006-04-15 | Ares Trading Sa | Verfahren zur reinigung von in bakterien exprimierten proteinen |
| GB0412400D0 (en) * | 2004-06-03 | 2004-07-07 | Univ Newcastle | Treatment of inflammatory conditions |
| EP2218748B1 (en) * | 2005-09-03 | 2012-10-10 | Samsung SDI Co., Ltd. | Polybenzoxazine-based compound, electrolyte membrane including the same, and fuel cell employing the electrolyte membrane |
| GB0614755D0 (en) | 2006-07-25 | 2006-09-06 | Univ Geneve | Cytokine derivatives |
| JP5624884B2 (ja) | 2007-08-02 | 2014-11-12 | ノビミューンエスアー | 抗rantes抗体およびその使用の方法 |
| WO2011097640A1 (en) * | 2010-02-08 | 2011-08-11 | The Trustees Of The University Of Pennsylvania | Nucleic acid molecules encoding rantes, and compositions comprising and methods of using the same |
| WO2019229615A1 (en) | 2018-05-28 | 2019-12-05 | Université De Genève | Methods of inhibiting cerebral inflammation |
| WO2022093857A1 (en) * | 2020-10-26 | 2022-05-05 | City Of Hope | Oncolytic virus compositions and methods for the treatment of cancer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5739103A (en) * | 1993-11-12 | 1998-04-14 | Dana-Farber Cancer Institute | Chemokine N-terminal deletion mutations |
| WO1998006751A1 (en) * | 1996-08-16 | 1998-02-19 | Research Corporation Technologies, Inc. | Mcp-3, rantes and mip-1alpha receptor antagonists |
| EP0906954A1 (en) * | 1997-09-29 | 1999-04-07 | Applied Research Systems ARS Holding N.V. | Amino-terminal truncated c-c chemokines as chemokine antagonist |
| CA2316447C (en) | 1997-12-23 | 2009-07-28 | Fondazione Centro San Raffaele Del Monte Tabor | Rantes mutants and therapeutic applications thereof |
| EP1148889A2 (en) | 1999-01-29 | 2001-10-31 | Millennium Pharmaceuticals, Inc. | Method of treating demyelinating inflammatory disease using ccr1 antagonists |
-
2001
- 2001-03-10 UA UA2003044038A patent/UA77950C2/uk unknown
- 2001-10-03 MX MXPA03003008A patent/MXPA03003008A/es active IP Right Grant
- 2001-10-03 HR HR20030215A patent/HRP20030215B1/xx not_active IP Right Cessation
- 2001-10-03 WO PCT/EP2001/011428 patent/WO2002028419A2/en not_active Ceased
- 2001-10-03 ES ES01986265T patent/ES2217199T3/es not_active Expired - Lifetime
- 2001-10-03 RS YUP-257/03A patent/RS50738B/sr unknown
- 2001-10-03 JP JP2002532243A patent/JP3908165B2/ja not_active Expired - Fee Related
- 2001-10-03 AU AU2002215919A patent/AU2002215919B2/en not_active Ceased
- 2001-10-03 KR KR1020037004599A patent/KR100837898B1/ko not_active Expired - Fee Related
- 2001-10-03 DK DK01986265T patent/DK1326628T3/da active
- 2001-10-03 CN CNB018199178A patent/CN1285381C/zh not_active Expired - Fee Related
- 2001-10-03 PL PL362350A patent/PL204231B1/pl not_active IP Right Cessation
- 2001-10-03 BR BR0114407-3A patent/BR0114407A/pt not_active IP Right Cessation
- 2001-10-03 IL IL15517801A patent/IL155178A0/xx unknown
- 2001-10-03 CA CA2423616A patent/CA2423616C/en not_active Expired - Fee Related
- 2001-10-03 PT PT01986265T patent/PT1326628E/pt unknown
- 2001-10-03 EP EP01986265A patent/EP1326628B1/en not_active Expired - Lifetime
- 2001-10-03 EA EA200300439A patent/EA006137B1/ru not_active IP Right Cessation
- 2001-10-03 DE DE60103078T patent/DE60103078T2/de not_active Expired - Lifetime
- 2001-10-03 SK SK406-2003A patent/SK287523B6/sk not_active IP Right Cessation
- 2001-10-03 AT AT01986265T patent/ATE265222T1/de active
- 2001-10-03 US US10/398,457 patent/US7402303B2/en not_active Expired - Fee Related
- 2001-10-03 CZ CZ20030947A patent/CZ303409B6/cs not_active IP Right Cessation
- 2001-10-03 EE EEP200300139A patent/EE05174B1/xx not_active IP Right Cessation
- 2001-10-03 AU AU1591902A patent/AU1591902A/xx active Pending
- 2001-10-03 HU HU0302194A patent/HUP0302194A3/hu unknown
- 2001-10-03 SI SI200130130T patent/SI1326628T1/xx unknown
- 2001-10-03 ZA ZA200302315A patent/ZA200302315B/en unknown
- 2001-10-04 AR ARP010104684A patent/AR030854A1/es unknown
-
2003
- 2003-03-28 BG BG107685A patent/BG66137B1/bg unknown
- 2003-04-01 IL IL155178A patent/IL155178A/en not_active IP Right Cessation
- 2003-04-03 NO NO20031525A patent/NO330278B1/no not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB1A | Change in the ownership or in the address of the owner | ||
| KB4A | Valid patent at the end of a year |
Effective date: 20101231 |
|
| HC1A | Change of owner name | ||
| MM4A | Lapsed by not paying the annual fees |
Effective date: 20131003 |