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EE04235B1 - Toimeainete, nimelt tetrahüdropüridiinide ja atsetüülkoliinesteraasi inhibiitorite, kombinatsioon Alzheimeri tõve tüüpi seniildementsuse raviks - Google Patents

Toimeainete, nimelt tetrahüdropüridiinide ja atsetüülkoliinesteraasi inhibiitorite, kombinatsioon Alzheimeri tõve tüüpi seniildementsuse raviks

Info

Publication number
EE04235B1
EE04235B1 EEP200000290A EEP200000290A EE04235B1 EE 04235 B1 EE04235 B1 EE 04235B1 EE P200000290 A EEP200000290 A EE P200000290A EE P200000290 A EEP200000290 A EE P200000290A EE 04235 B1 EE04235 B1 EE 04235B1
Authority
EE
Estonia
Prior art keywords
tetrahydropyridines
alzheimer
namely
treatment
combination
Prior art date
Application number
EEP200000290A
Other languages
English (en)
Estonian (et)
Inventor
Maffrand Jean-Pierre
Soubrie Philippe
Terranova Jean-Paul
Original Assignee
Sanofi-Synthlabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9714324A external-priority patent/FR2771006B1/fr
Priority claimed from FR9714322A external-priority patent/FR2771007B1/fr
Application filed by Sanofi-Synthlabo filed Critical Sanofi-Synthlabo
Publication of EE200000290A publication Critical patent/EE200000290A/xx
Publication of EE04235B1 publication Critical patent/EE04235B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EEP200000290A 1997-11-14 1998-11-09 Toimeainete, nimelt tetrahüdropüridiinide ja atsetüülkoliinesteraasi inhibiitorite, kombinatsioon Alzheimeri tõve tüüpi seniildementsuse raviks EE04235B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9714324A FR2771006B1 (fr) 1997-11-14 1997-11-14 Association de principes actifs pour le traitement de la demence senile du type alzheimer
FR9714322A FR2771007B1 (fr) 1997-11-14 1997-11-14 Association de principes actifs pour le traitement de la demence senile du type alzheimer
PCT/FR1998/002384 WO1999025363A1 (fr) 1997-11-14 1998-11-09 Association de principes actifs, notamment de tetrahydropyridines et d'agents inhibiteurs de l'acetylcholinesterase, pour le traitement de la demence senile du type alzheimer

Publications (2)

Publication Number Publication Date
EE200000290A EE200000290A (et) 2001-06-15
EE04235B1 true EE04235B1 (et) 2004-02-16

Family

ID=26233932

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000290A EE04235B1 (et) 1997-11-14 1998-11-09 Toimeainete, nimelt tetrahüdropüridiinide ja atsetüülkoliinesteraasi inhibiitorite, kombinatsioon Alzheimeri tõve tüüpi seniildementsuse raviks

Country Status (27)

Country Link
EP (1) EP1030671A1 (xx)
JP (1) JP2001523642A (xx)
KR (1) KR100599350B1 (xx)
CN (1) CN1243540C (xx)
AU (1) AU743228B2 (xx)
BG (1) BG64819B1 (xx)
BR (1) BR9814035A (xx)
CA (1) CA2309966A1 (xx)
CO (1) CO4980891A1 (xx)
DZ (1) DZ2649A1 (xx)
EA (1) EA003255B1 (xx)
EE (1) EE04235B1 (xx)
HU (1) HUP0100098A3 (xx)
ID (1) ID24933A (xx)
IL (2) IL136122A0 (xx)
IS (1) IS5482A (xx)
MY (1) MY120461A (xx)
NO (1) NO20002450L (xx)
NZ (1) NZ504420A (xx)
OA (1) OA11464A (xx)
PL (1) PL194597B1 (xx)
SA (1) SA98190747B1 (xx)
SK (1) SK286040B6 (xx)
TR (1) TR200001262T2 (xx)
TW (1) TW585766B (xx)
UY (1) UY25247A1 (xx)
WO (1) WO1999025363A1 (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0311780B8 (pt) * 2002-06-14 2021-05-25 Toyama Chemical Co Ltd composição farmacêutica para melhorar a função cerebral
DE60328198D1 (de) * 2002-08-07 2009-08-13 Novartis Ag Verfahren zur Vorhersage des Behandlungserfolgs mit Rivastigmine basierend auf einer Bestimmung des ApoE Genotyps eines Demenzkranken
CN1520818A (zh) * 2003-02-09 2004-08-18 山东绿叶天然药物研究开发有限公司 治疗老年性痴呆的胆碱酯酶抑制剂药物组合物
US8481565B2 (en) 2004-12-27 2013-07-09 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
EP4023294A1 (en) 2014-01-31 2022-07-06 Cognition Therapeutics, Inc. Isoindoline compositions and methods for treating alzheimer's disease
KR102614814B1 (ko) 2017-05-15 2023-12-20 카그니션 테라퓨틱스, 인코퍼레이티드 신경변성 질환 치료용 조성물
WO2019182319A1 (ko) * 2018-03-20 2019-09-26 (주)인벤티지랩 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물의 제조 방법 및 이의 제조 방법으로 제조된 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물
KR102224918B1 (ko) 2018-03-20 2021-03-09 (주)인벤티지랩 도네페질 및 메만틴을 포함하는 인지 장애 관련 질병의 예방 또는 치료용 약학적 복합 조성물 및 이의 제조 방법
CN109265391B (zh) * 2018-11-13 2021-11-19 枣庄学院 联苯多取代1,2,5,6-四氢吡啶化合物及其合成方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
US5453428A (en) * 1991-02-14 1995-09-26 The Mount Sinai School Of Medicine Of The City Of New York Method and composition for the treatment of apathy-amotivation syndrome
CN1126546C (zh) * 1995-03-06 2003-11-05 英特纽隆制剂药有限公司 使用胞磷胆碱减少梗塞面积
FR2736053B1 (fr) * 1995-06-28 1997-09-19 Sanofi Sa Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines

Also Published As

Publication number Publication date
WO1999025363A1 (fr) 1999-05-27
JP2001523642A (ja) 2001-11-27
TW585766B (en) 2004-05-01
IL136122A0 (en) 2001-05-20
EE200000290A (et) 2001-06-15
EA200000412A1 (ru) 2000-12-25
CA2309966A1 (en) 1999-05-27
BG104428A (en) 2001-08-31
AU743228B2 (en) 2002-01-24
TR200001262T2 (tr) 2001-01-22
DZ2649A1 (fr) 2004-12-28
AU1160999A (en) 1999-06-07
NZ504420A (en) 2003-08-29
CN1243540C (zh) 2006-03-01
SK286040B6 (sk) 2008-01-07
PL340500A1 (en) 2001-02-12
KR100599350B1 (ko) 2006-07-12
MY120461A (en) 2005-10-31
HUP0100098A2 (hu) 2001-07-30
IL136122A (en) 2006-07-05
SK7112000A3 (en) 2000-10-09
IS5482A (is) 2000-05-09
EP1030671A1 (fr) 2000-08-30
OA11464A (en) 2003-11-18
HUP0100098A3 (en) 2001-12-28
CN1285742A (zh) 2001-02-28
BR9814035A (pt) 2000-09-26
BG64819B1 (bg) 2006-05-31
PL194597B1 (pl) 2007-06-29
UY25247A1 (es) 2001-05-31
KR20010032099A (ko) 2001-04-16
CO4980891A1 (es) 2000-11-27
NO20002450L (no) 2000-07-14
SA98190747B1 (ar) 2006-11-04
NO20002450D0 (no) 2000-05-11
EA003255B1 (ru) 2003-02-27
ID24933A (id) 2000-08-31

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Legal Events

Date Code Title Description
HD1A Correction of address
HC1A Change of owner name
KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20081109