IL136122A0 - Combination of active principles, in particular of tetrahydropyridines and acetylcholinesterase inhibiting agents, for treating senile dementia such as alzheimer dementia - Google Patents
Combination of active principles, in particular of tetrahydropyridines and acetylcholinesterase inhibiting agents, for treating senile dementia such as alzheimer dementiaInfo
- Publication number
- IL136122A0 IL136122A0 IL13612298A IL13612298A IL136122A0 IL 136122 A0 IL136122 A0 IL 136122A0 IL 13612298 A IL13612298 A IL 13612298A IL 13612298 A IL13612298 A IL 13612298A IL 136122 A0 IL136122 A0 IL 136122A0
- Authority
- IL
- Israel
- Prior art keywords
- dementia
- tetrahydropyridines
- combination
- active principles
- inhibiting agents
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9714324A FR2771006B1 (fr) | 1997-11-14 | 1997-11-14 | Association de principes actifs pour le traitement de la demence senile du type alzheimer |
| FR9714322A FR2771007B1 (fr) | 1997-11-14 | 1997-11-14 | Association de principes actifs pour le traitement de la demence senile du type alzheimer |
| PCT/FR1998/002384 WO1999025363A1 (fr) | 1997-11-14 | 1998-11-09 | Association de principes actifs, notamment de tetrahydropyridines et d'agents inhibiteurs de l'acetylcholinesterase, pour le traitement de la demence senile du type alzheimer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL136122A0 true IL136122A0 (en) | 2001-05-20 |
Family
ID=26233932
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13612298A IL136122A0 (en) | 1997-11-14 | 1998-11-09 | Combination of active principles, in particular of tetrahydropyridines and acetylcholinesterase inhibiting agents, for treating senile dementia such as alzheimer dementia |
| IL136122A IL136122A (en) | 1997-11-14 | 2000-05-14 | Compounds of active ingredients, especially inhibitors of tetrahydropyridines and acetylcholinesterase carriers, for the treatment of dementia in adults, such as Alzheimer's dementia |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL136122A IL136122A (en) | 1997-11-14 | 2000-05-14 | Compounds of active ingredients, especially inhibitors of tetrahydropyridines and acetylcholinesterase carriers, for the treatment of dementia in adults, such as Alzheimer's dementia |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP1030671A1 (xx) |
| JP (1) | JP2001523642A (xx) |
| KR (1) | KR100599350B1 (xx) |
| CN (1) | CN1243540C (xx) |
| AU (1) | AU743228B2 (xx) |
| BG (1) | BG64819B1 (xx) |
| BR (1) | BR9814035A (xx) |
| CA (1) | CA2309966A1 (xx) |
| CO (1) | CO4980891A1 (xx) |
| DZ (1) | DZ2649A1 (xx) |
| EA (1) | EA003255B1 (xx) |
| EE (1) | EE04235B1 (xx) |
| HU (1) | HUP0100098A3 (xx) |
| ID (1) | ID24933A (xx) |
| IL (2) | IL136122A0 (xx) |
| IS (1) | IS5482A (xx) |
| MY (1) | MY120461A (xx) |
| NO (1) | NO20002450L (xx) |
| NZ (1) | NZ504420A (xx) |
| OA (1) | OA11464A (xx) |
| PL (1) | PL194597B1 (xx) |
| SA (1) | SA98190747B1 (xx) |
| SK (1) | SK286040B6 (xx) |
| TR (1) | TR200001262T2 (xx) |
| TW (1) | TW585766B (xx) |
| UY (1) | UY25247A1 (xx) |
| WO (1) | WO1999025363A1 (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4675103B2 (ja) * | 2002-06-14 | 2011-04-20 | 富山化学工業株式会社 | 脳機能を改善する医薬組成物および脳機能を改善するための方法 |
| CA2494585A1 (en) * | 2002-08-07 | 2004-02-19 | Novartis Ag | Methods for the treatment of dementia based on apo e genotype |
| CN1520818A (zh) * | 2003-02-09 | 2004-08-18 | 山东绿叶天然药物研究开发有限公司 | 治疗老年性痴呆的胆碱酯酶抑制剂药物组合物 |
| CA2592605C (en) | 2004-12-27 | 2010-12-07 | Eisai R&D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
| CN106163516B (zh) | 2014-01-31 | 2019-05-28 | 考格尼申治疗股份有限公司 | 异吲哚啉组合物和治疗神经变性疾病的方法 |
| CN110869011B (zh) | 2017-05-15 | 2024-01-05 | 考格尼申治疗股份有限公司 | 用于治疗神经退行性疾病的组合物 |
| KR102224918B1 (ko) | 2018-03-20 | 2021-03-09 | (주)인벤티지랩 | 도네페질 및 메만틴을 포함하는 인지 장애 관련 질병의 예방 또는 치료용 약학적 복합 조성물 및 이의 제조 방법 |
| WO2019182319A1 (ko) * | 2018-03-20 | 2019-09-26 | (주)인벤티지랩 | 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물의 제조 방법 및 이의 제조 방법으로 제조된 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물 |
| CN109265391B (zh) * | 2018-11-13 | 2021-11-19 | 枣庄学院 | 联苯多取代1,2,5,6-四氢吡啶化合物及其合成方法与应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2662355B1 (fr) * | 1990-05-22 | 1994-11-10 | Sanofi Sa | Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux. |
| US5453428A (en) * | 1991-02-14 | 1995-09-26 | The Mount Sinai School Of Medicine Of The City Of New York | Method and composition for the treatment of apathy-amotivation syndrome |
| JPH11511732A (ja) * | 1995-03-06 | 1999-10-12 | インターニューロン ファーマシューティカルズ,インコーポレーテッド | シチコリンを用いる梗塞容積の低減 |
| FR2736053B1 (fr) * | 1995-06-28 | 1997-09-19 | Sanofi Sa | Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines |
-
1998
- 1998-10-26 CO CO98062479A patent/CO4980891A1/es unknown
- 1998-10-28 TW TW087117874A patent/TW585766B/zh not_active IP Right Cessation
- 1998-11-09 CA CA002309966A patent/CA2309966A1/en not_active Abandoned
- 1998-11-09 KR KR1020007005231A patent/KR100599350B1/ko not_active Expired - Fee Related
- 1998-11-09 PL PL98340500A patent/PL194597B1/pl not_active IP Right Cessation
- 1998-11-09 TR TR2000/01262T patent/TR200001262T2/xx unknown
- 1998-11-09 IL IL13612298A patent/IL136122A0/xx not_active IP Right Cessation
- 1998-11-09 HU HU0100098A patent/HUP0100098A3/hu unknown
- 1998-11-09 WO PCT/FR1998/002384 patent/WO1999025363A1/fr not_active Ceased
- 1998-11-09 EP EP98954538A patent/EP1030671A1/fr not_active Withdrawn
- 1998-11-09 SK SK711-2000A patent/SK286040B6/sk unknown
- 1998-11-09 CN CNB988130947A patent/CN1243540C/zh not_active Expired - Fee Related
- 1998-11-09 AU AU11609/99A patent/AU743228B2/en not_active Ceased
- 1998-11-09 JP JP2000520796A patent/JP2001523642A/ja not_active Withdrawn
- 1998-11-09 BR BR9814035-3A patent/BR9814035A/pt not_active Application Discontinuation
- 1998-11-09 EE EEP200000290A patent/EE04235B1/xx not_active IP Right Cessation
- 1998-11-09 ID IDW20000860A patent/ID24933A/id unknown
- 1998-11-09 EA EA200000412A patent/EA003255B1/ru not_active IP Right Cessation
- 1998-11-09 NZ NZ504420A patent/NZ504420A/en unknown
- 1998-11-11 DZ DZ980259A patent/DZ2649A1/xx active
- 1998-11-12 UY UY25247A patent/UY25247A1/es not_active IP Right Cessation
- 1998-11-14 SA SA98190747A patent/SA98190747B1/ar unknown
- 1998-11-14 MY MYPI98005180A patent/MY120461A/en unknown
-
2000
- 2000-05-09 IS IS5482A patent/IS5482A/is unknown
- 2000-05-11 BG BG104428A patent/BG64819B1/bg unknown
- 2000-05-11 NO NO20002450A patent/NO20002450L/no unknown
- 2000-05-12 OA OA1200000141A patent/OA11464A/en unknown
- 2000-05-14 IL IL136122A patent/IL136122A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |