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EE04911B1 - Ühend ja farmatseutiline kompositsioon proteaasi inhibiitoritena, nende kasutamine ning meetod selle ühendi valmistamiseks - Google Patents

Ühend ja farmatseutiline kompositsioon proteaasi inhibiitoritena, nende kasutamine ning meetod selle ühendi valmistamiseks

Info

Publication number
EE04911B1
EE04911B1 EEP200100485A EEP200100485A EE04911B1 EE 04911 B1 EE04911 B1 EE 04911B1 EE P200100485 A EEP200100485 A EE P200100485A EE P200100485 A EEP200100485 A EE P200100485A EE 04911 B1 EE04911 B1 EE 04911B1
Authority
EE
Estonia
Prior art keywords
compound
protease inhibitors
preparing
pharmaceutical composition
oxides
Prior art date
Application number
EEP200100485A
Other languages
English (en)
Estonian (et)
Inventor
M. Bryant Clifford
A. Bunin Barry
A. Kraynack Erica
W. Patterson John
Original Assignee
Axys Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axys Pharmaceuticals, Inc. filed Critical Axys Pharmaceuticals, Inc.
Publication of EE200100485A publication Critical patent/EE200100485A/xx
Publication of EE04911B1 publication Critical patent/EE04911B1/xx

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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
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