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EE03377B1 - Farmatseutilised liposoomsüstepreparaadid - Google Patents

Farmatseutilised liposoomsüstepreparaadid

Info

Publication number
EE03377B1
EE03377B1 EE9500063A EE9500063A EE03377B1 EE 03377 B1 EE03377 B1 EE 03377B1 EE 9500063 A EE9500063 A EE 9500063A EE 9500063 A EE9500063 A EE 9500063A EE 03377 B1 EE03377 B1 EE 03377B1
Authority
EE
Estonia
Prior art keywords
phospholipid
pharmaceutical preparations
liposomal injection
cryoprotector
cooa
Prior art date
Application number
EE9500063A
Other languages
English (en)
Other versions
EE9500063A (et
Inventor
Hamann Hans-J�rgen
Serno Peter
Herboth Matthias
Kurka Peter
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of EE9500063A publication Critical patent/EE9500063A/et
Publication of EE03377B1 publication Critical patent/EE03377B1/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906Drug delivery
    • Y10S977/907Liposome
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915Therapeutic or pharmaceutical composition

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • External Artificial Organs (AREA)
  • Glass Compositions (AREA)
EE9500063A 1994-09-12 1995-09-11 Farmatseutilised liposoomsüstepreparaadid EE03377B1 (et)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4432378A DE4432378A1 (de) 1994-09-12 1994-09-12 Injizierbare liposomale Arzneizubereitungen

Publications (2)

Publication Number Publication Date
EE9500063A EE9500063A (et) 1996-04-15
EE03377B1 true EE03377B1 (et) 2001-04-16

Family

ID=6527981

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9500063A EE03377B1 (et) 1994-09-12 1995-09-11 Farmatseutilised liposoomsüstepreparaadid

Country Status (28)

Country Link
US (1) US5653998A (et)
EP (1) EP0700679B1 (et)
JP (1) JPH0881361A (et)
KR (1) KR960009998A (et)
CN (1) CN1079668C (et)
AT (1) ATE187327T1 (et)
AU (1) AU698441B2 (et)
CA (1) CA2157849A1 (et)
CZ (1) CZ287975B6 (et)
DE (2) DE4432378A1 (et)
DK (1) DK0700679T3 (et)
EE (1) EE03377B1 (et)
ES (1) ES2139800T3 (et)
FI (1) FI954204A7 (et)
GR (1) GR3032664T3 (et)
HU (1) HUT73808A (et)
IL (1) IL115222A (et)
MY (1) MY111841A (et)
NO (1) NO311556B1 (et)
NZ (1) NZ272943A (et)
PL (1) PL181541B1 (et)
PT (1) PT700679E (et)
RU (1) RU2160099C2 (et)
SI (1) SI0700679T1 (et)
SK (1) SK281611B6 (et)
TW (1) TW359616B (et)
UA (1) UA29469C2 (et)
ZA (1) ZA957604B (et)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
DE19709704C2 (de) 1997-03-10 1999-11-04 Michael Georgieff Verwendung einer flüssigen Präparation von Xenon zur intravenösen Verabreichung bei Einleitung und/oder Aufrechterhaltung der Anaesthesie
US7030155B2 (en) 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
KR20000003433A (ko) * 1998-06-29 2000-01-15 김영환 반도체소자의 커패시터 제조방법
ATE397488T1 (de) * 1998-11-13 2008-06-15 Heriot William A Vorrichtung zur herstellung von liposomen
HK1044897A1 (zh) * 1999-05-14 2002-11-08 Esperion Luv Development Inc. 心绞痛和/或不典型心绞痛的治疗方法及其相关药物组合物和药剂盒
EP1259225B1 (en) 2000-02-04 2006-10-04 Lipoxen Technologies Limited Process of dehydration/rehydration for making liposomes
US20060177416A1 (en) 2003-10-14 2006-08-10 Medivas, Llc Polymer particle delivery compositions and methods of use
EP1530465B2 (en) 2002-06-26 2015-12-16 MediGene AG Method of producing a cationic liposomal preparation comprising a lipophilic compound
DE10255195A1 (de) 2002-11-27 2004-06-09 Lipoid Gmbh Micellare wasserlösliche Konzentrate
WO2005002546A1 (en) * 2003-06-27 2005-01-13 Smithkline Beecham Corporation Stabilized topotecan liposomal composition and methods
US7345093B2 (en) * 2004-04-27 2008-03-18 Formatech, Inc. Methods of enhancing solubility of compounds
WO2006094203A1 (en) * 2005-03-02 2006-09-08 Northeastern University Mitochondriotropic phospholipid vesicles
SI1888033T1 (sl) * 2005-06-09 2014-06-30 Meda Ab Postopek in sestavek za zdravljenje vnetnih motenj
JP5178520B2 (ja) 2005-09-22 2013-04-10 メディバス エルエルシー 固体ポリマー送達組成物およびその使用法
JP5192384B2 (ja) 2005-09-22 2013-05-08 メディバス エルエルシー ビス−(α−アミノ)−ジオール−ジエステル含有ポリ(エステルアミド)およびポリ(エステルウレタン)組成物および使用の方法
WO2008000534A1 (de) * 2006-06-30 2008-01-03 Gertrud Langhoff Solubilisatformulierungen
JP6081058B2 (ja) * 2009-03-19 2017-02-15 第一三共株式会社 包装により安定保存された固形製剤
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
US20110070293A1 (en) * 2009-09-23 2011-03-24 Javeri Indu Methods for the Preparation of Liposomes Comprising Docetaxel
US20110070294A1 (en) * 2009-09-23 2011-03-24 Javeri Indu Methods for the Administration of Drugs Using Liposomes
IT1404011B1 (it) 2010-12-03 2013-11-08 Uni Degli Studi Magna Graecia Di Catanzaro Nanovettore coniugato con tsh per il trattamento del cancro della tiroide
PL226015B1 (pl) * 2011-03-03 2017-06-30 Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Liposomowy preparat zawierajacy przeciwnowotworowa substancje aktywna, sposob jego wytwarzania i zawierajaca go kompozycja farmaceutyczna
CN103748139B (zh) 2011-06-23 2016-08-17 帝斯曼知识产权资产管理有限公司 用于递送生物活性剂的包含生物可降解的聚酯酰胺共聚物的微米颗粒或纳米颗粒
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
FR2979239A1 (fr) * 2011-08-25 2013-03-01 Trophos Liposome comprenant au moins un derive de cholesterol
EP2682106A1 (en) 2012-07-03 2014-01-08 Phares Pharmaceutical Research N.V. Method of solubilizing biologically active compounds
CA2893342A1 (en) * 2012-12-06 2014-06-12 D & J Rosee Inc. Topical liposome compositions containing phenolic anti-inflammatory agents and their methods of preparation
JP6720447B2 (ja) 2014-12-18 2020-07-08 ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. 酸感受性薬剤の送達のための薬剤送達系
CN110898011B (zh) * 2019-11-27 2022-02-08 西南医科大学 一种依托咪酯纳米制剂及其制备方法
KR20220125259A (ko) * 2019-12-23 2022-09-14 잠본쏘시에떼퍼아찌오니 흡입성 면역억제 활성 성분을 포함하는 분산액의 제조 방법
JP7608086B2 (ja) * 2020-07-31 2025-01-06 東和薬品株式会社 シームレスカプセル

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3515335C2 (de) * 1985-04-27 1995-01-26 Bayer Ag Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
DE4117750A1 (de) * 1991-05-30 1992-12-24 Bayer Ag Neue 2-amino-5-cyano-1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE4207481A1 (de) * 1992-03-10 1993-09-16 Bayer Ag Liposomale wirkstoff-formulierungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ATE187327T1 (de) 1999-12-15
SK281611B6 (sk) 2001-05-10
TW359616B (en) 1999-06-01
UA29469C2 (uk) 2000-11-15
HU9502654D0 (en) 1995-11-28
NO953578D0 (no) 1995-09-11
AU3046495A (en) 1996-03-28
ES2139800T3 (es) 2000-02-16
IL115222A0 (en) 1995-12-31
EP0700679A1 (de) 1996-03-13
FI954204L (fi) 1996-03-13
DK0700679T3 (da) 2000-05-29
ZA957604B (en) 1996-04-15
CZ287975B6 (cs) 2001-03-14
DE59507372D1 (de) 2000-01-13
PL181541B1 (pl) 2001-08-31
CA2157849A1 (en) 1996-03-13
US5653998A (en) 1997-08-05
EE9500063A (et) 1996-04-15
NO311556B1 (no) 2001-12-10
SK112795A3 (en) 1997-02-05
FI954204A7 (fi) 1996-03-13
SI0700679T1 (en) 2000-02-29
NZ272943A (en) 1996-07-26
EP0700679B1 (de) 1999-12-08
CZ234195A3 (en) 1996-03-13
JPH0881361A (ja) 1996-03-26
KR960009998A (ko) 1996-04-20
IL115222A (en) 1999-06-20
AU698441B2 (en) 1998-10-29
PT700679E (pt) 2000-05-31
MY111841A (en) 2001-01-31
NO953578L (no) 1996-03-13
GR3032664T3 (en) 2000-06-30
PL310344A1 (en) 1996-03-18
DE4432378A1 (de) 1996-03-14
FI954204A0 (fi) 1995-09-08
CN1079668C (zh) 2002-02-27
RU2160099C2 (ru) 2000-12-10
CN1128655A (zh) 1996-08-14
HUT73808A (en) 1996-09-30

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

MM4A Lapsed by not paying the annual fees

Effective date: 20020911