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DK619284A - Udtrykkelsesplasmid til forbedret produktion af heterologt protein ibakterier og fremgangsmaade til fremstilling af dette protein samtfremgangsmaade til fremstilling af plasmidet - Google Patents

Udtrykkelsesplasmid til forbedret produktion af heterologt protein ibakterier og fremgangsmaade til fremstilling af dette protein samtfremgangsmaade til fremstilling af plasmidet Download PDF

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Publication number
DK619284A
DK619284A DK619284A DK619284A DK619284A DK 619284 A DK619284 A DK 619284A DK 619284 A DK619284 A DK 619284A DK 619284 A DK619284 A DK 619284A DK 619284 A DK619284 A DK 619284A
Authority
DK
Denmark
Prior art keywords
preparation
expression
protein
plasmid
preparing
Prior art date
Application number
DK619284A
Other languages
English (en)
Other versions
DK619284D0 (da
DK173028B1 (da
Inventor
Arthur Ernest Franke
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK619284D0 publication Critical patent/DK619284D0/da
Publication of DK619284A publication Critical patent/DK619284A/da
Application granted granted Critical
Publication of DK173028B1 publication Critical patent/DK173028B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Lubricants (AREA)
DK198406192A 1983-12-23 1984-12-21 Nucleotidsekvens, ekspressionsplasmid indeholdende nucleotidsekvensen til forbedret produktion af heterologt protein i bakt DK173028B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56496283A 1983-12-23 1983-12-23
US56496283 1983-12-23

Publications (3)

Publication Number Publication Date
DK619284D0 DK619284D0 (da) 1984-12-21
DK619284A true DK619284A (da) 1985-06-24
DK173028B1 DK173028B1 (da) 1999-11-22

Family

ID=24256628

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198406192A DK173028B1 (da) 1983-12-23 1984-12-21 Nucleotidsekvens, ekspressionsplasmid indeholdende nucleotidsekvensen til forbedret produktion af heterologt protein i bakt

Country Status (8)

Country Link
EP (1) EP0147178B1 (da)
JP (2) JP2532365B2 (da)
AT (1) ATE66251T1 (da)
BR (1) BR8406680A (da)
CA (1) CA1340867C (da)
DE (1) DE3484926D1 (da)
DK (1) DK173028B1 (da)
IE (1) IE57651B1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758512A (en) * 1984-03-06 1988-07-19 President And Fellows Of Harvard College Hosts and methods for producing recombinant products in high yields
US4743679A (en) * 1986-02-24 1988-05-10 Creative Biomolecules, Inc. Process for producing human epidermal growth factor and analogs thereof
GB8701848D0 (en) * 1987-01-28 1987-03-04 Celltech Ltd Polypeptides
US5472702A (en) * 1987-08-26 1995-12-05 United States Surgical Corporation Sterilization of growth factors
US5366081A (en) 1987-08-26 1994-11-22 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5222978A (en) 1987-08-26 1993-06-29 United States Surgical Corporation Packaged synthetic absorbable surgical elements
DE68915841T2 (de) * 1988-03-30 1995-02-02 Hitachi Chemical Co Ltd Verfahren zur Herstellung von Epidermal-Wachstumsfaktor durch genetische Transformation.
US5359831A (en) 1989-08-01 1994-11-01 United States Surgical Corporation Molded suture retainer
CA2059245C (en) * 1991-02-08 2004-07-06 Michael P. Chesterfield Method and apparatus for calendering and coating/filling sutures
JP3550440B2 (ja) * 1995-04-13 2004-08-04 イーストマン・コダックジャパン株式会社 オートホワイトバランス調整装置
US5904716A (en) * 1995-04-26 1999-05-18 Gendler; El Method for reconstituting cartilage tissue using demineralized bone and product thereof
US20090192554A1 (en) 2008-01-29 2009-07-30 Confluent Surgical, Inc. Bioabsorbable block copolymer

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1200773A (en) * 1980-02-29 1986-02-18 William J. Rutter Expression linkers
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
DK489481A (da) * 1980-11-10 1982-05-11 Searle & Co Plasmidvektor og frmgangsmaade til fremstilling deraf
BR8108074A (pt) * 1980-12-12 1982-09-21 Unilever Nv Sequencia de dna,plasmidio recombinante,ligadores de dna,cultura bacterial e processo para produzir taumatina
JPS589687A (ja) * 1981-06-17 1983-01-20 セルテク　リミテッド ポリペプチドの生産方法
IE53517B1 (en) * 1981-06-17 1988-12-07 Celltech Ltd Process for the production of a polypeptide
NZ201918A (en) * 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
BR8205954A (pt) * 1981-10-14 1983-09-13 Unilever Nv Sequencia de dna,plasmidio recombinante,cultura bacteriana e microorganismos
IL68100A0 (en) * 1982-03-24 1983-06-15 Takeda Chemical Industries Ltd Novel dna and use thereof
KR840004164A (ko) * 1982-03-24 1984-10-10 구라바야시 이꾸시로 Dna 및 그의 이용
EP0108132A1 (en) * 1982-05-06 1984-05-16 Applied Molecular Genetics Inc. The manufacture and expression of genes for urogastrone and polypeptide analogs thereof
US4582800A (en) * 1982-07-12 1986-04-15 Hoffmann-La Roche Inc. Novel vectors and method for controlling interferon expression
EP0121569B1 (en) * 1982-10-08 1990-08-22 Kyowa Hakko Kogyo Co., Ltd. Novel vector
IE56372B1 (en) * 1982-12-22 1991-07-03 Genentech Inc Microbially produced rennet methods for its production and plasmids used for its production

Also Published As

Publication number Publication date
EP0147178B1 (en) 1991-08-14
ATE66251T1 (de) 1991-08-15
CA1340867C (en) 2000-01-04
JPH0272892A (ja) 1990-03-13
DK619284D0 (da) 1984-12-21
JPH0630612B2 (ja) 1994-04-27
EP0147178A3 (en) 1987-06-03
BR8406680A (pt) 1985-10-22
JP2532365B2 (ja) 1996-09-11
IE57651B1 (en) 1993-02-10
DE3484926D1 (de) 1991-09-19
EP0147178A2 (en) 1985-07-03
DK173028B1 (da) 1999-11-22
IE843270L (en) 1985-06-23
JPS60227682A (ja) 1985-11-12

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)