[go: up one dir, main page]

BR8406680A - Processo para preparacao de um plasmidio,processo para expressao eficiente de proteinas heterologas,para preparacao de um transformante e processo para producao de prorrenina - Google Patents

Processo para preparacao de um plasmidio,processo para expressao eficiente de proteinas heterologas,para preparacao de um transformante e processo para producao de prorrenina

Info

Publication number
BR8406680A
BR8406680A BR8406680A BR8406680A BR8406680A BR 8406680 A BR8406680 A BR 8406680A BR 8406680 A BR8406680 A BR 8406680A BR 8406680 A BR8406680 A BR 8406680A BR 8406680 A BR8406680 A BR 8406680A
Authority
BR
Brazil
Prior art keywords
preparing
expression
proteins
prorrenin
plasmide
Prior art date
Application number
BR8406680A
Other languages
English (en)
Inventor
Arthur Ernest Franke
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR8406680A publication Critical patent/BR8406680A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Lubricants (AREA)
BR8406680A 1983-12-23 1984-12-21 Processo para preparacao de um plasmidio,processo para expressao eficiente de proteinas heterologas,para preparacao de um transformante e processo para producao de prorrenina BR8406680A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56496283A 1983-12-23 1983-12-23

Publications (1)

Publication Number Publication Date
BR8406680A true BR8406680A (pt) 1985-10-22

Family

ID=24256628

Family Applications (1)

Application Number Title Priority Date Filing Date
BR8406680A BR8406680A (pt) 1983-12-23 1984-12-21 Processo para preparacao de um plasmidio,processo para expressao eficiente de proteinas heterologas,para preparacao de um transformante e processo para producao de prorrenina

Country Status (8)

Country Link
EP (1) EP0147178B1 (pt)
JP (2) JP2532365B2 (pt)
AT (1) ATE66251T1 (pt)
BR (1) BR8406680A (pt)
CA (1) CA1340867C (pt)
DE (1) DE3484926D1 (pt)
DK (1) DK173028B1 (pt)
IE (1) IE57651B1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758512A (en) * 1984-03-06 1988-07-19 President And Fellows Of Harvard College Hosts and methods for producing recombinant products in high yields
US4743679A (en) * 1986-02-24 1988-05-10 Creative Biomolecules, Inc. Process for producing human epidermal growth factor and analogs thereof
GB8701848D0 (en) * 1987-01-28 1987-03-04 Celltech Ltd Polypeptides
US5222978A (en) 1987-08-26 1993-06-29 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5366081A (en) 1987-08-26 1994-11-22 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5472702A (en) * 1987-08-26 1995-12-05 United States Surgical Corporation Sterilization of growth factors
DE68915841T2 (de) * 1988-03-30 1995-02-02 Hitachi Chemical Co Ltd Verfahren zur Herstellung von Epidermal-Wachstumsfaktor durch genetische Transformation.
US5359831A (en) 1989-08-01 1994-11-01 United States Surgical Corporation Molded suture retainer
CA2059245C (en) * 1991-02-08 2004-07-06 Michael P. Chesterfield Method and apparatus for calendering and coating/filling sutures
JP3550440B2 (ja) * 1995-04-13 2004-08-04 イーストマン・コダックジャパン株式会社 オートホワイトバランス調整装置
US5904716A (en) * 1995-04-26 1999-05-18 Gendler; El Method for reconstituting cartilage tissue using demineralized bone and product thereof
US20090192554A1 (en) 2008-01-29 2009-07-30 Confluent Surgical, Inc. Bioabsorbable block copolymer

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1200773A (en) * 1980-02-29 1986-02-18 William J. Rutter Expression linkers
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
DK489481A (da) * 1980-11-10 1982-05-11 Searle & Co Plasmidvektor og frmgangsmaade til fremstilling deraf
DE3175357D1 (en) * 1980-12-12 1986-10-23 Unilever Nv Dna sequences encoding various allelic forms of mature thaumatin, recombinant plasmids comprising said dna's and a process for their preparation, bacterial cultures comprising said recombinant plasmids, and method for producing mature thaumatin
JPS589687A (ja) * 1981-06-17 1983-01-20 セルテク　リミテッド ポリペプチドの生産方法
IE53517B1 (en) * 1981-06-17 1988-12-07 Celltech Ltd Process for the production of a polypeptide
NZ201918A (en) * 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
BR8205954A (pt) * 1981-10-14 1983-09-13 Unilever Nv Sequencia de dna,plasmidio recombinante,cultura bacteriana e microorganismos
JPS58189197A (ja) * 1982-03-24 1983-11-04 Takeda Chem Ind Ltd 新規ｄｎａおよびその用途
IL68100A0 (en) * 1982-03-24 1983-06-15 Takeda Chemical Industries Ltd Novel dna and use thereof
WO1983004030A1 (en) * 1982-05-06 1983-11-24 Applied Molecular Genetics, Inc. The manufacture and expression of genes for urogastrone and polypeptide analogs thereof
US4582800A (en) * 1982-07-12 1986-04-15 Hoffmann-La Roche Inc. Novel vectors and method for controlling interferon expression
EP0121569B1 (en) * 1982-10-08 1990-08-22 Kyowa Hakko Kogyo Co., Ltd. Novel vector
IE56372B1 (en) * 1982-12-22 1991-07-03 Genentech Inc Microbially produced rennet methods for its production and plasmids used for its production

Also Published As

Publication number Publication date
DE3484926D1 (de) 1991-09-19
JPH0272892A (ja) 1990-03-13
EP0147178A2 (en) 1985-07-03
JP2532365B2 (ja) 1996-09-11
DK619284A (da) 1985-06-24
ATE66251T1 (de) 1991-08-15
JPH0630612B2 (ja) 1994-04-27
JPS60227682A (ja) 1985-11-12
CA1340867C (en) 2000-01-04
EP0147178A3 (en) 1987-06-03
DK173028B1 (da) 1999-11-22
EP0147178B1 (en) 1991-08-14
IE57651B1 (en) 1993-02-10
DK619284D0 (da) 1984-12-21
IE843270L (en) 1985-06-23

Similar Documents

Publication Publication Date Title
IL68366A (en) Process for expressing a gene encoding a protein comprising the enzymatic portion of human urokinase in a microorganism or cell culture
ATE46536T1 (de) Verfahren zur herstellung von reifen proteinen in wirtzellen von wirbeltieren.
IE820069L (en) Recombinant dna encoding a polypeptide
DE69332981D1 (de) Methoden zur herstellung löslicher, oligomerer proteine
BR8406680A (pt) Processo para preparacao de um plasmidio,processo para expressao eficiente de proteinas heterologas,para preparacao de um transformante e processo para producao de prorrenina
ATE111156T1 (de) Transientes expressionssystem zur herstellung von rekombinantem protein.
DE69836092D1 (de) Rekombinatorisches klonieren unter verwendung von nukleinsaüren mit rekombinationsstellen
ATE209679T1 (de) Proteine mit faktor viii aktivität, verfahren zu deren herstellung unter verwendung von genetisch modifizierten zellen und diese enthaltende zusammensetzungen
ATE318917T1 (de) Verfahren zur bakteriellen herstellung von heterologen polypeptiden mit disulfidbrücke
ATE188736T1 (de) Endothelin-dna und verwendung davon
ES8700868A1 (es) Metodo de aislamiento de un fragmento de gen que codifica por lo menos una porcion de una proteina.
DK139493A (da) Rekombinant plasmid, bakteriekultur transformeret dermed samt kulturens anvendelse
FI863891L (fi) Menetelmiä sekropiinin ja muiden heterologisten polypeptidien tuottamiseksi bakteeri-isännässä araB-promoottoria käyttäen sekä menetelmissä käyttökelpoisia replikoituvia ekspressiovälineitä, geneettisiä muodostelmia ja bakteereja
IL94722A0 (en) Media for cell growth and their production
KR910004803A (ko) 간의 실질 세포 성장 인자, 이를 코딩하는 유전자, 이 인자를 생산하는 방법, 및 이 인자를 생산하는 형질전환체
SE8303626D0 (sv) A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced
AU588793B2 (en) Method of expressing alpha-1-antitrypsin in bacteria
DE3175357D1 (en) Dna sequences encoding various allelic forms of mature thaumatin, recombinant plasmids comprising said dna's and a process for their preparation, bacterial cultures comprising said recombinant plasmids, and method for producing mature thaumatin
KR840008697A (ko) 상동 효모 신호를 이용한 이종단백질의 합성, 분비 및 표현매개체 제조방법
DE3769872D1 (de) Herstellung von rekombinantem protein.
CA1312566C (en) Method for increasing the expression of polypeptides in recombinant cell culture
DK0387646T3 (da) Achromobacter-protease I-gen og genprodukt deraf
DE3681398D1 (de) Verfahren zur herstellung von insulinaehnlichem wachstumsfaktor i (igf-i) und plasmid zu dessen herstellung.
DE3677421D1 (de) Mikrobiologisches verfahren zur herstellung von menschlichem lysozym.
DE58909205D1 (de) Expressionsvektor und Verfahren zur regulierbaren Herstellung von Proteinen in Eukaryonten.

Legal Events

Date Code Title Description
KD Notifcation of receipt (letter patent)
FG Letter patent granted
B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 21/12/99