DK377882A - Fremgangsmaade til fremstilling af (3h)-imidazo-(5,1-d)-1,2,3,5-tetrazin-4-on-derivater - Google Patents

Fremgangsmaade til fremstilling af (3h)-imidazo-(5,1-d)-1,2,3,5-tetrazin-4-on-derivater Download PDF

Info

Publication number: DK377882A
Authority: DK; Denmark
Prior art keywords: tetrazin; imidazo; derivatives; preparing
Prior art date: 1981-08-24

Application number

DK377882A

Other languages

English (en)

Other versions

DK161147C (da

DK161147B (da

Inventor

Edward Lunt

Malcolm Francis Graham Stevens

Robert Stone

Kenneth Robert Harr Wooldridge

Original Assignee

May & Baker Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-08-24

Filing date

1982-08-23

Publication date

1983-02-25

1982-08-23 Application filed by May & Baker Ltd filed Critical May & Baker Ltd

1983-02-25 Publication of DK377882A publication Critical patent/DK377882A/da

1991-06-03 Publication of DK161147B publication Critical patent/DK161147B/da

1991-11-18 Application granted granted Critical

1991-11-18 Publication of DK161147C publication Critical patent/DK161147C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DK377882A 1981-08-24 1982-08-23 Analogifremgangsmaade til fremstilling af oe3haa-imidazo-oe5,1-daa-1,2,3,5-tetrazin-4-onderivater DK161147C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8125791		1981-08-24
GB8125791		1981-08-24

Publications (3)

Publication Number	Publication Date
DK377882A true DK377882A (da)	1983-02-25
DK161147B DK161147B (da)	1991-06-03
DK161147C DK161147C (da)	1991-11-18

Family

ID=10524141

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK377882A DK161147C (da)	1981-08-24	1982-08-23	Analogifremgangsmaade til fremstilling af oe3haa-imidazo-oe5,1-daa-1,2,3,5-tetrazin-4-onderivater

Country Status (29)

Country	Link
JP (1)	JPS5843975A (da)
KR (1)	KR890000094B1 (da)
AT (1)	AT380256B (da)
AU (1)	AU571430B2 (da)
BE (1)	BE894175A (da)
CA (1)	CA1197247A (da)
CH (1)	CH655114A5 (da)
DE (2)	DE3231255A1 (da)
DK (1)	DK161147C (da)
ES (1)	ES515176A0 (da)
FI (1)	FI73434C (da)
FR (1)	FR2511679A1 (da)
GB (1)	GB2104522B (da)
GE (1)	GEP19960641B (da)
GR (1)	GR76863B (da)
HU (1)	HU186107B (da)
IE (1)	IE53408B1 (da)
IL (1)	IL66606A (da)
IT (1)	IT1152505B (da)
LT (1)	LT2436B (da)
LU (1)	LU84347A1 (da)
LV (2)	LV5511A3 (da)
NL (2)	NL192739C (da)
NZ (1)	NZ201668A (da)
OA (1)	OA07174A (da)
SE (1)	SE448543B (da)
SU (1)	SU1447284A3 (da)
UA (1)	UA5971A1 (da)
ZA (1)	ZA826120B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5260291A (en) *	1981-08-24	1993-11-09	Cancer Research Campaign Technology Limited	Tetrazine derivatives
GR78688B (da) *	1982-08-17	1984-09-27	May & Baker Ltd
GB2125402B (en) *	1982-08-17	1985-11-13	May & Baker Ltd	New tetrazine derivatives
US4517182A (en) *	1983-05-24	1985-05-14	Warner-Lambert Company	3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) *	1986-07-02	1986-08-06	May & Baker Ltd	Compositions of matter
AU622330B2 (en) *	1989-06-23	1992-04-02	Takeda Chemical Industries Ltd.	Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
CZ292102B6 (cs) *	1995-09-25	2003-07-16	Sanofi-Synthelabo Inc.	Vodný parenterální prostředek pro léčbu rakovinových nádorů
CA2552095A1 (en) *	2003-12-30	2005-07-14	Chemagis Ltd.	Novel crystalline forms of temozolomide
ES2552338T3 (es)	2005-01-21	2015-11-27	Astex Therapeutics Limited	Compuestos farmacéuticos
PE20080695A1 (es)	2006-04-27	2008-06-28	Banyu Pharma Co Ltd	Derivados de dihidropirazolopirimidinona como inhibidores de quinasa weel
JP2008081492A (ja)	2006-08-31	2008-04-10	Banyu Pharmaceut Co Ltd	オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
EP2073807A1 (en)	2006-10-12	2009-07-01	Astex Therapeutics Limited	Pharmaceutical combinations
EP2073803B1 (en)	2006-10-12	2018-09-19	Astex Therapeutics Limited	Pharmaceutical combinations
AU2008315048A1 (en)	2007-10-23	2009-04-30	Msd K.K.	Pyridone-substituted-dihydropyrazolopyrimidinone derivative
PE20091101A1 (es) *	2007-12-18	2009-07-26	Pharminox Ltd	AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
JP2012509868A (ja) *	2008-11-24	2012-04-26	リライアンスライフサイエンシズピーヴィーティーリミティッド	テトラジン誘導体の製造方法
WO2010101734A1 (en)	2009-03-06	2010-09-10	Merck Sharp & Dohme Corp.	Combination cancer therapy with an akt inhibitor and other anticancer agents
AU2010264339A1 (en)	2009-06-23	2011-12-22	Pharminox Limited	3-substituted-8-substituted-3H imidazo[5,1-d][1,2,3,5-tetrazin-4-one compounds and their use
RU2462466C1 (ru) *	2011-06-24	2012-09-27	Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан"	Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ
EP2766041B1 (en)	2011-10-12	2018-12-05	Children's Medical Center Corporation	Combinatorial compositions and methods of treating hemoglobinopathies
CN109195593A (zh)	2016-03-15	2019-01-11	奥莱松基因组股份有限公司	用于治疗实体瘤的lsd1抑制剂的组合
KR101847342B1 (ko) *	2017-05-08	2018-04-11	(주)센텍코리아	웨어러블 체지방 연소량 측정기

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2932305A1 (de) *	1979-08-09	1981-02-26	Basf Ag	Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

1982
- 1982-08-05 OA OA57766BISD patent/OA07174A/xx unknown
- 1982-08-12 IL IL66606A patent/IL66606A/xx not_active IP Right Cessation
- 1982-08-23 DK DK377882A patent/DK161147C/da not_active IP Right Cessation
- 1982-08-23 UA UA3482389A patent/UA5971A1/uk unknown
- 1982-08-23 JP JP57144902A patent/JPS5843975A/ja active Granted
- 1982-08-23 AU AU87493/82A patent/AU571430B2/en not_active Expired
- 1982-08-23 SU SU823482389A patent/SU1447284A3/ru active
- 1982-08-23 LU LU84347A patent/LU84347A1/fr unknown
- 1982-08-23 IE IE2026/82A patent/IE53408B1/en not_active IP Right Cessation
- 1982-08-23 IT IT22938/82A patent/IT1152505B/it active Protection Beyond IP Right Term
- 1982-08-23 GB GB08224155A patent/GB2104522B/en not_active Expired
- 1982-08-23 ES ES515176A patent/ES515176A0/es active Granted
- 1982-08-23 NL NL8203286A patent/NL192739C/nl not_active IP Right Cessation
- 1982-08-23 KR KR8203774A patent/KR890000094B1/ko not_active Expired
- 1982-08-23 AT AT0319182A patent/AT380256B/de not_active IP Right Cessation
- 1982-08-23 FI FI822921A patent/FI73434C/fi not_active IP Right Cessation
- 1982-08-23 BE BE0/208860A patent/BE894175A/fr not_active IP Right Cessation
- 1982-08-23 CA CA000409950A patent/CA1197247A/fr not_active Expired
- 1982-08-23 SE SE8204817A patent/SE448543B/sv not_active IP Right Cessation
- 1982-08-23 GR GR69093A patent/GR76863B/el unknown
- 1982-08-23 ZA ZA826120A patent/ZA826120B/xx unknown
- 1982-08-23 HU HU822708A patent/HU186107B/hu unknown
- 1982-08-23 DE DE19823231255 patent/DE3231255A1/de active Granted
- 1982-08-23 DE DE1999175037 patent/DE19975037I2/de active Active
- 1982-08-23 NZ NZ201668A patent/NZ201668A/en unknown
- 1982-08-23 CH CH5007/82A patent/CH655114A5/fr not_active IP Right Cessation
- 1982-08-23 FR FR8214461A patent/FR2511679A1/fr active Granted
1993
- 1993-06-19 LV LV930621A patent/LV5511A3/xx unknown
- 1993-09-29 LT LTRP1286A patent/LT2436B/xx not_active IP Right Cessation
- 1993-11-16 GE GEAP19931653A patent/GEP19960641B/en unknown
- 1993-12-03 LV LV931303A patent/LV5621A3/xx unknown
1999
- 1999-04-01 NL NL990010C patent/NL990010I2/nl unknown

Also Published As

Publication number	Publication date
LT2436B (lt)	1994-02-15
CH655114A5 (fr)	1986-03-27
JPS5843975A (ja)	1983-03-14
DK161147C (da)	1991-11-18
FI73434C (fi)	1987-10-09
AU8749382A (en)	1983-03-03
NL990010I1 (nl)	1999-07-01
SU1447284A3 (ru)	1988-12-23
DE3231255C2 (da)	1992-02-27
NL192739C (nl)	1998-01-06
DE19975037I2 (de)	2001-06-13
FI822921L (fi)	1983-02-25
SE448543B (sv)	1987-03-02
NZ201668A (en)	1985-08-16
GR76863B (da)	1984-09-04
IL66606A (en)	1987-07-31
CA1197247A (fr)	1985-11-26
JPH045029B2 (da)	1992-01-30
KR840001175A (ko)	1984-03-28
SE8204817L (sv)	1983-02-25
FR2511679B1 (da)	1985-02-01
ES8400438A1 (es)	1983-11-01
NL8203286A (nl)	1983-03-16
DE3231255A1 (de)	1983-03-03
LV5621A3 (lv)	1994-05-10
UA5971A1 (uk)	1994-12-29
KR890000094B1 (ko)	1989-03-07
AT380256B (de)	1986-05-12
ES515176A0 (es)	1983-11-01
ZA826120B (en)	1983-07-27
OA07174A (fr)	1984-04-30
GB2104522A (en)	1983-03-09
IE822026L (en)	1983-02-24
DK161147B (da)	1991-06-03
NL990010I2 (nl)	1999-09-01
IE53408B1 (en)	1988-11-09
IL66606A0 (en)	1982-12-31
HU186107B (en)	1985-06-28
FI822921A0 (fi)	1982-08-23
IT8222938A0 (it)	1982-08-23
GB2104522B (en)	1985-06-12
ATA319182A (de)	1985-09-15
LV5511A3 (lv)	1994-03-10
BE894175A (fr)	1983-02-23
AU571430B2 (en)	1988-04-21
GEP19960641B (en)	1996-11-15
FR2511679A1 (fr)	1983-02-25
FI73434B (fi)	1987-06-30
IT8222938A1 (it)	1984-02-23
LU84347A1 (fr)	1983-06-07
NL192739B (nl)	1997-09-01
IT1152505B (it)	1987-01-07
SE8204817D0 (sv)	1982-08-23

Publication	Publication Date	Title
DK377882A (da)	1983-02-25	Fremgangsmaade til fremstilling af (3h)-imidazo-(5,1-d)-1,2,3,5-tetrazin-4-on-derivater
DK280182A (da)	1982-12-24	Fremgangsmaade til fremstilling af n-aryl-piperazinalkanamider
DK159442C (da)	1991-03-18	Analogifremgangsmaade til fremstilling af 6,7-substitueret-4-ethyl-quinazoliner
DK470583D0 (da)	1983-10-12	Fremgangsmade til fremstilling af 1-phenyl-2-piperidinopropanolderivater
DK143491D0 (da)	1991-08-06	Fremgangsmaade til fremstilling af 3-oen-phenylacetylaminopiperidinaa-2,6-dion
DK262782A (da)	1982-12-13	Fremgangsmaade til fremstilling af n-dihydrothiazolyl-3-quinolincarboxamidderivater
DK379985A (da)	1986-03-06	Fremgangsmaade til fremstilling af 6-chlor-n-methyl-2,3,4,5-tetrahydro-lh-benzazepin
DK155281C (da)	1989-07-24	Fremgangsmaade til fremstilling af 1,2-dihydro-6-methyl-2-oxo-5-(pyridinyl)nicotinonitriler
DK157855C (da)	1990-07-30	Fremgangsmaade til fremstilling af 2,3-dichlor-5-trichlormethylpyridin
ES517022A0 (es)	1984-08-16	Procedimiento de preparar compuestos 1,4-dihidropiridinicos.
DK312082A (da)	1983-01-14	Fremgangsmaade til fremstilling af benzothiazolsulfonamidderivater
DK156722C (da)	1990-02-19	Analogifremgangsmaade til fremstilling af 2-piperazinopyrimidinderivater
DK370582A (da)	1983-02-20	Fremgangsmaade til fremstilling af 2-beta-d-ribofuranosylthiazol-4-carboxamid
DK113483A (da)	1983-03-08	Fremgangsmaade til fremstilling af 3,4-diphenyl-5-methylpyrazolderivater
DK158227C (da)	1990-09-17	Analogifremgangsmaade til fremstilling af substituerede imidazooe1,5-aaapyridiner eller 5,6,7,8-tetrahydroderivater deraf eller salte deraf
DK154207C (da)	1989-03-13	Fremgangsmaade til fremstilling af 1,8-dihydroxy-10-acyl-9-anthroner
DK153488C (da)	1988-12-19	Fremgangsmaade til fremstilling af 5,6,7,7a-tetrahydro-4h-thieno(3,2-c-)-pyridin-2-onderivater
DK97682A (da)	1982-09-07	Fremgangsmaade til fremstilling af 1-(1,3-benzodioxol-5-yl)-2-pyrrolidinon
DK79982A (da)	1982-08-26	Fremgangsmaade til fremstilling af 3-(4-phenyl-1-piperazinio-1-yl)-1,2-propandiol-3-(theophyllin-7-yl)-1-propan-sulfonat
FI822647A7 (fi)	1983-01-30	4-amino-butyramidin valmistusmenetelmä.
DK513580A (da)	1981-07-08	Fremgangsmaade til fremstilling af 4,5-diaryl-alfa (polyhalogenalkyl)-1h-imidazol-2-methanoler
DK454183D0 (da)	1983-09-30	Fremgangsmade til fremstilling af 15-cycloaliphatiske derivater af 13,14-didehydro-carboprostancycliner
DK389484D0 (da)	1984-08-13	Fremgangsmaade til fremstilling af 2,3-dihydrobenzopyranonderivater
DK253882A (da)	1982-12-06	Fremgangsmaade til fremstilling af 4-aminobenzylaminderivater
DK231482A (da)	1982-11-23	Fremgangsmaade til fremstilling af beta-lactamringholdige derivater

Legal Events

Date	Code	Title	Description
1999-08-16	CTFF	Application for supplementary protection certificate (spc) filed	Free format text: CA 1999 00012, 19990511, EXPIRES: 20070823
2002-09-09	PUP	Patent expired