DK0777490T3 - Mutant-enterotoxin, som er effektivt som et ikke-toksisk oralt adjuvans - Google Patents

Mutant-enterotoxin, som er effektivt som et ikke-toksisk oralt adjuvans

Info

Publication number: DK0777490T3
Authority: DK; Denmark
Prior art keywords: effective; enterotoxin; oral adjuvant; toxic oral; mutant enterotoxin
Prior art date: 1994-08-26

Application number

DK95928662T

Other languages

English (en)

Inventor

John D Clements

Bonny L Dickinson

Original Assignee

Univ Tulane

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-26

Filing date

1995-07-18

Publication date

2006-09-18

1995-07-18 Application filed by Univ Tulane filed Critical Univ Tulane

2006-09-18 Application granted granted Critical

2006-09-18 Publication of DK0777490T3 publication Critical patent/DK0777490T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0258—Escherichia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Mycology (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Pulmonology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Carbon And Carbon Compounds (AREA)
Dental Preparations (AREA)
Compositions Of Macromolecular Compounds (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

DK95928662T 1994-08-26 1995-07-18 Mutant-enterotoxin, som er effektivt som et ikke-toksisk oralt adjuvans DK0777490T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/296,848 US6019982A (en)	1994-08-26	1994-08-26	Mutant enterotoxin effective as a non-toxic oral adjuvant

Publications (1)

Publication Number	Publication Date
DK0777490T3 true DK0777490T3 (da)	2006-09-18

Family

ID=23143827

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95928662T DK0777490T3 (da)	1994-08-26	1995-07-18	Mutant-enterotoxin, som er effektivt som et ikke-toksisk oralt adjuvans

Country Status (22)

Country	Link
US (2)	US6019982A (da)
EP (1)	EP0777490B1 (da)
JP (1)	JP3860208B2 (da)
KR (1)	KR100399258B1 (da)
CN (1)	CN1182868C (da)
AT (1)	ATE326231T1 (da)
AU (1)	AU709779B2 (da)
BR (1)	BR9508633A (da)
CA (1)	CA2198586C (da)
CZ (1)	CZ298131B6 (da)
DE (1)	DE69534992T2 (da)
DK (1)	DK0777490T3 (da)
ES (1)	ES2265148T3 (da)
FI (1)	FI120137B (da)
HU (1)	HU222985B1 (da)
NO (1)	NO317942B1 (da)
NZ (1)	NZ291262A (da)
PL (1)	PL182667B1 (da)
PT (1)	PT777490E (da)
RU (1)	RU2160606C2 (da)
WO (1)	WO1996006627A1 (da)
ZA (1)	ZA956412B (da)

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1994
- 1994-08-26 US US08/296,848 patent/US6019982A/en not_active Expired - Lifetime
1995
- 1995-07-18 BR BR9508633A patent/BR9508633A/pt not_active Application Discontinuation
- 1995-07-18 ES ES95928662T patent/ES2265148T3/es not_active Expired - Lifetime
- 1995-07-18 PL PL95318930A patent/PL182667B1/pl not_active IP Right Cessation
- 1995-07-18 DK DK95928662T patent/DK0777490T3/da active
- 1995-07-18 EP EP95928662A patent/EP0777490B1/en not_active Expired - Lifetime
- 1995-07-18 DE DE69534992T patent/DE69534992T2/de not_active Expired - Lifetime
- 1995-07-18 AT AT95928662T patent/ATE326231T1/de active
- 1995-07-18 KR KR1019970701224A patent/KR100399258B1/ko not_active Expired - Fee Related
- 1995-07-18 JP JP50873596A patent/JP3860208B2/ja not_active Expired - Fee Related
- 1995-07-18 WO PCT/US1995/009005 patent/WO1996006627A1/en not_active Ceased
- 1995-07-18 HU HU9801472A patent/HU222985B1/hu not_active IP Right Cessation
- 1995-07-18 RU RU97104479/14A patent/RU2160606C2/ru not_active IP Right Cessation
- 1995-07-18 AU AU32337/95A patent/AU709779B2/en not_active Ceased
- 1995-07-18 PT PT95928662T patent/PT777490E/pt unknown
- 1995-07-18 CA CA2198586A patent/CA2198586C/en not_active Expired - Fee Related
- 1995-07-18 NZ NZ291262A patent/NZ291262A/xx not_active IP Right Cessation
- 1995-07-18 CN CNB951958380A patent/CN1182868C/zh not_active Expired - Fee Related
- 1995-07-18 CZ CZ0056297A patent/CZ298131B6/cs not_active IP Right Cessation
- 1995-08-01 ZA ZA956412A patent/ZA956412B/xx unknown
1997
- 1997-02-26 FI FI970799A patent/FI120137B/fi not_active IP Right Cessation
- 1997-03-04 NO NO19970993A patent/NO317942B1/no not_active IP Right Cessation
1999
- 1999-08-02 US US09/365,530 patent/US6440423B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ZA956412B (en)	1996-03-11
CZ298131B6 (cs)	2007-07-04
NO970993D0 (no)	1997-03-04
FI120137B (fi)	2009-07-15
KR970705403A (ko)	1997-10-09
RU2160606C2 (ru)	2000-12-20
PL182667B1 (pl)	2002-02-28
WO1996006627A1 (en)	1996-03-07
CZ56297A3 (en)	1997-10-15
HUT77869A (hu)	1998-09-28
HU222985B1 (hu)	2004-01-28
EP0777490A1 (en)	1997-06-11
CA2198586A1 (en)	1996-03-07
AU709779B2 (en)	1999-09-09
DE69534992D1 (de)	2006-06-22
JP3860208B2 (ja)	2006-12-20
NO317942B1 (no)	2005-01-10
US6440423B1 (en)	2002-08-27
CN1164191A (zh)	1997-11-05
EP0777490B1 (en)	2006-05-17
CN1182868C (zh)	2005-01-05
FI970799L (fi)	1997-04-24
FI970799A0 (fi)	1997-02-26
ES2265148T3 (es)	2007-02-01
US6019982A (en)	2000-02-01
DE69534992T2 (de)	2007-05-10
ATE326231T1 (de)	2006-06-15
NZ291262A (en)	1999-02-25
EP0777490A4 (en)	1998-11-18
CA2198586C (en)	2010-10-12
BR9508633A (pt)	1997-09-30
KR100399258B1 (ko)	2003-12-31
PT777490E (pt)	2006-10-31
PL318930A1 (en)	1997-07-21
JPH10505059A (ja)	1998-05-19
NO970993L (no)	1997-04-25
AU3233795A (en)	1996-03-22
MX9701445A (es)	1998-05-31

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DK0777490T3 (da)	2006-09-18	Mutant-enterotoxin, som er effektivt som et ikke-toksisk oralt adjuvans
DE69421939D1 (de)	2000-01-05	Nichttoxisches schleimhautadjuvans
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NZ323973A (en)	2004-12-24	Vaccine compositions for intranasal administration comprising chitosan and use thereof
AU2147992A (en)	1993-01-12	Immunogen compounds having specifically an anti-cytokine effect, method of preparation, pharmaceutical compositions and kits containing them
PT764029E (pt)	2002-10-31	Adjuvantes proteicos
EE03016B1 (et)	1997-08-15	Peroraalselt manustatav ravimvorm tsentraalse dopamiinipuuduse-seisundi ravimiseks ja selle valmistamise meetod
SE9003198D0 (sv)	1990-10-05	Fish vaccine comprising a virulent, invasive bacterium
AU2001284354A1 (en)	2002-02-13	Immunological adjuvant compounds, compositions, and methods of use thereof
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DK0725653T3 (da)	2004-10-11	Vaccinepræparater
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HUP9700975A2 (hu)	1998-05-28	Élő, legyengített, Pasteurellaceae családba tartozó, RTX-termelő baktériumok
NO913131L (no)	1992-02-14	Immunogene konjugater av ikke-toksisk oligosakkarid fra bordetella pertussis lipoolysakkarid.
EA200200704A1 (ru)	2003-08-28	Ослабленные микроорганизмы для лечения инфекции
AU6942896A (en)	1997-03-27	Use of muteins of wild-type cytokines as immunogens
CA2388054A1 (en)	2001-05-25	Compositions and methods for stimulating an immune response against infectious agents
AU7960101A (en)	2002-02-18	Parenteral vaccine formulations and uses thereof
RU96116250A (ru)	1998-01-20	Штамм pestivirus, используемый для изготовления лапинизированной вирус вакцины против классической чумы свиней
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