[go: up one dir, main page]

DE69932424D1 - Melanocortin 1 rezeptorselektive verbindungen - Google Patents

Melanocortin 1 rezeptorselektive verbindungen

Info

Publication number
DE69932424D1
DE69932424D1 DE69932424T DE69932424T DE69932424D1 DE 69932424 D1 DE69932424 D1 DE 69932424D1 DE 69932424 T DE69932424 T DE 69932424T DE 69932424 T DE69932424 T DE 69932424T DE 69932424 D1 DE69932424 D1 DE 69932424D1
Authority
DE
Germany
Prior art keywords
aminoacid
alkyl
compound
receptors
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69932424T
Other languages
English (en)
Other versions
DE69932424T2 (de
Inventor
Michael Szardenings
Ruta Muceniece
Ilze Mutule
Felikss Mutulis
Jarl Wikberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Action Pharma AS
Original Assignee
Action Pharma AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Action Pharma AS filed Critical Action Pharma AS
Application granted granted Critical
Publication of DE69932424D1 publication Critical patent/DE69932424D1/de
Publication of DE69932424T2 publication Critical patent/DE69932424T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C07K14/685—Alpha-melanotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrane Compounds (AREA)
  • Cosmetics (AREA)
DE69932424T 1998-05-05 1999-05-05 Melanocortin-1-rezeptor-selektive verbindungen Expired - Lifetime DE69932424T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9801571A SE9801571D0 (sv) 1998-05-05 1998-05-05 Melanokortin-1-receptorselektiva föreningar
SE9801571 1998-05-05
PCT/GB1999/001388 WO1999057148A1 (en) 1998-05-05 1999-05-05 Melanocortin 1 receptor selective compounds

Publications (2)

Publication Number Publication Date
DE69932424D1 true DE69932424D1 (de) 2006-08-31
DE69932424T2 DE69932424T2 (de) 2007-02-22

Family

ID=20411194

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69932424T Expired - Lifetime DE69932424T2 (de) 1998-05-05 1999-05-05 Melanocortin-1-rezeptor-selektive verbindungen

Country Status (14)

Country Link
US (2) US7008925B1 (de)
EP (2) EP1693382A3 (de)
JP (1) JP4584450B2 (de)
AT (1) ATE333468T1 (de)
AU (1) AU765120B2 (de)
CA (1) CA2327550A1 (de)
CY (1) CY1105654T1 (de)
DE (1) DE69932424T2 (de)
DK (1) DK1075492T3 (de)
ES (1) ES2268862T3 (de)
NZ (1) NZ507792A (de)
PT (1) PT1075492E (de)
SE (1) SE9801571D0 (de)
WO (1) WO1999057148A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ506839A (en) 1998-03-09 2003-05-30 Zealand Pharma As Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
SE9801571D0 (sv) 1998-05-05 1998-05-05 Wapharm Ab Melanokortin-1-receptorselektiva föreningar
US7176279B2 (en) 2000-06-28 2007-02-13 Palatin Technologies, Inc. Cyclic peptide compositions and methods for treatment of sexual dysfunction
WO2002006316A2 (en) * 2000-07-14 2002-01-24 Zycos, Inc. Alpha-msh related compounds and methods of use
AU2002238106A1 (en) 2001-02-13 2002-08-28 Palatin Technologies, Inc. Melanocortin metallopeptides for treatment of sexual dysfunction
DE10106852A1 (de) * 2001-02-14 2002-09-05 T Luger Entzündungshemmende Verbindungen
US20080009019A1 (en) * 2001-06-13 2008-01-10 Smithkline Beecham Corporation High throughput method for screening candidate compounds for biological activity
FR2826581B1 (fr) * 2001-06-29 2005-10-07 Oreal Utilisation du tripeptide lys-pro-val (kpv) dans le traitement des melanomes
FR2826580B1 (fr) * 2001-06-29 2005-09-30 Oreal Utilisation du tripeptide lys-pro-val (kpv) pour favoriser le renouvellement epidermique et la micro-cicatrisation cutanee superficielle et/ou ameliorer l'aspect esthetique des plaies et cicatrices
SI1919947T1 (sl) 2005-08-26 2013-06-28 Abbvie Inc. Terapevtsko aktivni alfa-msh analogi
KR20100057054A (ko) * 2007-09-11 2010-05-28 몬도바이오테크 래보래토리즈 아게 치료제로서의 터프친의 용도
AU2009257631B2 (en) 2008-06-09 2014-07-24 Palatin Technologies, Inc. Melanocortin receptor-specific peptides for treatment of sexual dysfunction
UY31877A (es) * 2008-06-09 2010-01-29 Palatin Technologies Inc Péptidos específicos de los receptores de melanocortina para el tratamiento de la obesidad / 669
AU2010259008C1 (en) 2009-06-08 2016-04-21 Palatin Technologies, Inc. Melanocortin receptor-specific peptides
UY32690A (es) * 2009-06-08 2011-01-31 Astrazeneca Ab Péptidos específicos para receptores de melanocortina
EP2440572B1 (de) 2009-06-08 2017-04-05 Palatin Technologies, Inc. Lactam-gebrückte melanocortinrezeptorspezifische peptide
CA2781402C (en) 2009-11-23 2017-03-21 Palatin Technologies, Inc. Melanocortin-1 receptor-specific cyclic peptides
CA2781405A1 (en) 2009-11-23 2011-05-26 Palatin Technologies, Inc. Melanocortin-1 receptor-specific linear peptides
JP5715104B2 (ja) * 2012-09-27 2015-05-07 アブビー インコーポレイティド 治療的に活性なα−ＭＳＨアナログ
ES2538702T3 (es) 2012-10-19 2015-06-23 Txp Pharma Gmbh Análogos de MSH-alfa y MSH-gamma
ES2854353T3 (es) 2014-04-22 2021-09-21 Txp Pharma Gmbh Análogos péptidicos con sonda(s) aminoacídicas ramificadas
US9939338B2 (en) 2015-02-19 2018-04-10 Stmicroelectronics S.R.L. Pressure sensing device with cavity and related methods
AU2016298175B2 (en) 2015-07-28 2022-01-06 University Of Iowa Research Foundation Compositions and methods of treating cancer
AU2017281940C1 (en) * 2016-06-24 2024-11-07 University Of Iowa Research Foundation Compositions and methods of treating melanoma
US11590209B2 (en) 2020-01-21 2023-02-28 Palatin Technologies, Inc. Use of bremelanotide in patients with controlled hypertension
US11529335B2 (en) 2020-07-31 2022-12-20 University Of Iowa Research Foundation Compositions and methods for treating cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4288627A (en) * 1980-02-12 1981-09-08 Phillips Petroleum Company Oxidation of thiols employing cobalt molybdate/triethylamine catalyst
AU639570B2 (en) 1990-05-09 1993-07-29 Novozymes A/S A cellulase preparation comprising an endoglucanase enzyme
US5814603A (en) 1992-06-12 1998-09-29 Affymax Technologies N.V. Compounds with PTH activity
US5731408A (en) 1995-04-10 1998-03-24 Arizona Board Of Regents On Behalf Of The University Of Arizona Peptides having potent antagonist and agonist bioactivities at melanocortin receptors
NZ506839A (en) 1998-03-09 2003-05-30 Zealand Pharma As Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
SE9801571D0 (sv) 1998-05-05 1998-05-05 Wapharm Ab Melanokortin-1-receptorselektiva föreningar
EP1076066A1 (de) 1999-07-12 2001-02-14 Zealand Pharmaceuticals A/S Peptide zur Senkung des Blutglukosespiegels
GB9927346D0 (en) 1999-11-18 2000-01-12 Melacure Therapeutics Ab Method for analysis and design of entities of a chemical or biochemical nature
GB0012370D0 (en) 2000-05-22 2000-07-12 Quadrant Holdings Cambridge Peptoids
SI1919947T1 (sl) * 2005-08-26 2013-06-28 Abbvie Inc. Terapevtsko aktivni alfa-msh analogi

Also Published As

Publication number Publication date
DE69932424T2 (de) 2007-02-22
US20070027086A1 (en) 2007-02-01
CA2327550A1 (en) 1999-11-11
SE9801571D0 (sv) 1998-05-05
PT1075492E (pt) 2006-11-30
ATE333468T1 (de) 2006-08-15
US7008925B1 (en) 2006-03-07
WO1999057148A1 (en) 1999-11-11
EP1693382A2 (de) 2006-08-23
US7662782B2 (en) 2010-02-16
EP1075492A1 (de) 2001-02-14
CY1105654T1 (el) 2010-12-22
DK1075492T3 (da) 2006-12-04
JP4584450B2 (ja) 2010-11-24
NZ507792A (en) 2003-10-31
AU765120B2 (en) 2003-09-11
EP1075492B1 (de) 2006-07-19
AU3722299A (en) 1999-11-23
ES2268862T3 (es) 2007-03-16
JP2002513555A (ja) 2002-05-14
EP1693382A3 (de) 2006-11-08

Similar Documents

Publication Publication Date Title
DE69932424D1 (de) Melanocortin 1 rezeptorselektive verbindungen
BRPI0006823B8 (pt) composição farmacêutica estabilizada, preparação de injeção, e kit comercial
MY141641A (en) Compositions comprising viruses and methods for concentrating virus preparations
MY142065A (en) Arylalkylamines, process for preparing them and pharmaceutical compositions containing them
DE69007429D1 (de) Isoindolonderivate, ihre Herstellung und diese enthaltende pharmazeutische Zusammensetzungen.
DK0498069T3 (da) Ny anvendelse af peptidderivat
LU90987I2 (fr) Copaxone et ses dérivés pharmaceutiquement acceptables
KR900006363A (ko) 신규한 펩티다제 억제제
TR200003844T2 (tr) Epotilon türevleri, sentezleri ve kullanımları
HUP0104452A2 (hu) Triciklusos vegyületeket tartalmazó gyógyászati kompozíció
KR930007972A (ko) 환상 혈관활성 펩티드
KR920021517A (ko) 중축 신경계에 활성인 신규의 3-아미노피리다진 유도체, 그의 제조방법 및 이들의 존재하는 약제학적 조성물
KR970707108A (ko) 항염증제로 유용한, 복소환부를 갖는 디-t-부틸페놀 화합물(DI-TERT-BUTYLPHENOL COMPOUNDS WITH HETEROCYCLIC MOIETY, USEFUL AS ANTI-INFLAMMATORY AGENTS)
KR930007969A (ko) 17β- 치환된 아자 - 안드로스탄 유도체
IL125081A0 (en) Ob protein receptor and related compositions and methods
KR900701828A (ko) 펩티드 화합물
TR200200125T2 (tr) Yeni aminotiyazol türevleri, bunların hazırlanması ve bunları içeren farmasötik kompozisyonlar.
HU896606D0 (en) Process for the preparation of aminoacid derivatives inhibiting enzymes and pharmaceutical compositions thereof
KR920700283A (ko) C-말단 아미드화 효소 조성물, 제조방법 및 이의 사용방법
CO5140099A1 (es) Ciertas caprolactamas sustituidas, composiciones farmaceuticas que las contienen, y su uso en el tratamiento de tumores
ATE131191T1 (de) Verträgliche polymermischungen.
KR960004366A (ko) 합성 펩타이드 유도체 및 이의염
ATE131159T1 (de) 1-alkyl-3-(acylamino)-epsilon-caprolactame zur verbesserung der lernfähigkeit und des gedächtnisses und diese enthaltende pharmazeutische zubereitungen.
MX9603199A (es) Antagonistas de receptores a endotelina.
MX9806249A (es) Dihidrobenzofurano y compuestos relacionados utiles como agentes antiinflamatorios.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition