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BRPI0006823B8 - composição farmacêutica estabilizada, preparação de injeção, e kit comercial - Google Patents

composição farmacêutica estabilizada, preparação de injeção, e kit comercial

Info

Publication number
BRPI0006823B8
BRPI0006823B8 BRPI0006823A BRPI0006823A BRPI0006823B8 BR PI0006823 B8 BRPI0006823 B8 BR PI0006823B8 BR PI0006823 A BRPI0006823 A BR PI0006823A BR PI0006823 A BRPI0006823 A BR PI0006823A BR PI0006823 B8 BRPI0006823 B8 BR PI0006823B8
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
injection preparation
commercial kit
stabilized pharmaceutical
stabilized
Prior art date
Application number
BRPI0006823A
Other languages
English (en)
Inventor
Kasai Akihiro
Otomo Kazumi
Sawai Seiji
Original Assignee
Astellas Pharma Inc
Fujisawa Pharmaceutical Co
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16210881&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0006823(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astellas Pharma Inc, Fujisawa Pharmaceutical Co, Yamanouchi Pharmaceutical Co Ltd filed Critical Astellas Pharma Inc
Publication of BRPI0006823B1 publication Critical patent/BRPI0006823B1/pt
Publication of BRPI0006823B8 publication Critical patent/BRPI0006823B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

composição farmacêutica estabilizada, uso de composto de polipeptídeo cíclico, preparação de injeção e pacote comercial. composição farmacêutica estabilizada na forma liofilizada compreendendo um composto de polipeptídeo cíclico representado pela fórmula geral (i) : onde r1 é um átomo de hidrogênio ou um grupo acila e r2 e r3 são, iguais ou diferentes, um átomo de hidrogênio ou um grupo hidroxila, ou um sal do mesmo e um estabilizante.
BRPI0006823A 1999-07-01 2000-06-29 composição farmacêutica estabilizada, preparação de injeção, e kit comercial BRPI0006823B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPHEI11-187713 1999-07-01
JP18771399 1999-07-01
PCT/JP2000/004381 WO2001002002A1 (en) 1999-07-01 2000-06-29 Stabilized pharmaceutical composition in lyophilized form

Publications (2)

Publication Number Publication Date
BRPI0006823B1 BRPI0006823B1 (pt) 2020-01-07
BRPI0006823B8 true BRPI0006823B8 (pt) 2021-05-25

Family

ID=16210881

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0006823A BRPI0006823B8 (pt) 1999-07-01 2000-06-29 composição farmacêutica estabilizada, preparação de injeção, e kit comercial
BR0006823-3A BR0006823A (pt) 1999-07-01 2000-06-29 Composição farmacêutica estabilizada, uso de composto de polipeptìdeo cìclico, preparação de injeção e pacote comercial

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR0006823-3A BR0006823A (pt) 1999-07-01 2000-06-29 Composição farmacêutica estabilizada, uso de composto de polipeptìdeo cìclico, preparação de injeção e pacote comercial

Country Status (28)

Country Link
US (2) US6774104B1 (pt)
EP (1) EP1107777B1 (pt)
JP (2) JP3381722B2 (pt)
KR (1) KR100454784B1 (pt)
CN (2) CN100352495C (pt)
AR (1) AR024634A1 (pt)
AT (1) ATE280583T1 (pt)
AU (1) AU752265B2 (pt)
BR (2) BRPI0006823B8 (pt)
CA (1) CA2341568C (pt)
CZ (1) CZ295720B6 (pt)
DE (1) DE60015279T2 (pt)
ES (1) ES2225161T3 (pt)
HK (1) HK1040057B (pt)
HU (1) HU229089B1 (pt)
ID (1) ID29468A (pt)
IL (2) IL141455A0 (pt)
MX (1) MXPA01000601A (pt)
NO (1) NO330353B1 (pt)
NZ (1) NZ510290A (pt)
OA (1) OA11601A (pt)
PL (1) PL200141B1 (pt)
PT (1) PT1107777E (pt)
RU (1) RU2251411C2 (pt)
TR (1) TR200100609T1 (pt)
TW (1) TWI233805B (pt)
WO (1) WO2001002002A1 (pt)
ZA (1) ZA200101589B (pt)

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TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
ITMI20021040A1 (it) * 2002-05-16 2003-11-17 Novuspharma Spa Composizioni farmaceutiche iniettabili di un derivato antracenedionico ad attivita' antitumorale
WO2004011001A1 (ja) 2002-07-31 2004-02-05 Senju Pharmaceutical Co., Ltd. 水性液剤および光安定化された水性液剤
US8877168B1 (en) 2002-07-31 2014-11-04 Senju Pharmaceuticals Co., Ltd. Aqueous liquid preparations and light-stabilized aqueous liquid preparations
US7119061B2 (en) * 2002-11-18 2006-10-10 Vicuron Pharmaceuticals, Inc. Dalbavancin compositions for treatment of bacterial infections
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
WO2004045637A1 (en) * 2002-11-18 2004-06-03 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
CA2558191C (en) 2004-03-04 2011-01-04 Eisai R&D Management Co., Ltd. Composition containing benzamidine derivative and method for stabilizing benzamidine derivative
US7514450B2 (en) * 2004-05-19 2009-04-07 Neurosearch A/S Azabicyclic aryl derivatives
EP1814591A4 (en) * 2004-11-22 2009-04-22 Anadis Ltd BIOACTIVE PREPARATIONS
KR101307999B1 (ko) 2004-12-01 2013-09-12 니폰 조키 세야쿠 가부시키가이샤 건조물 및 그 제조방법
KR20080028942A (ko) * 2005-07-20 2008-04-02 교와 메덱스 가부시키가이샤 생체 시료 중의 펩티드의 안정화 방법
CN1962852B (zh) * 2006-11-27 2011-11-09 西北农林科技大学 红景天多糖在制备抗冻剂中的新用途及其产品和制备方法
CN102614491B (zh) * 2011-01-31 2014-04-16 上海天伟生物制药有限公司 一种含有棘白菌素类抗真菌剂米卡芬净的药用组合物及其制备方法和用途
CN102614492B (zh) * 2011-01-31 2013-12-11 上海天伟生物制药有限公司 一种含有棘白菌素类抗真菌剂米卡芬净的液体药用组合物
UA115063C2 (uk) * 2012-05-22 2017-09-11 ПАЙОН ЮКей ЛІМІТЕД Композиції, які містять бензодіазепіни короткої дії
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US20140274997A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Cephalosporin pharmaceutical compositions
AU2014227660B2 (en) 2013-03-15 2014-11-06 Merck Sharp & Dohme Llc Ceftolozane antibiotic compositions
CN103330932B (zh) * 2013-04-26 2015-12-23 江苏豪森药业股份有限公司 一种米卡芬净或其盐的药物组合物
CN103330933B (zh) * 2013-04-26 2015-08-05 江苏豪森药业股份有限公司 含有米卡芬净或其盐的药物组合物
CA2914261C (en) * 2013-06-05 2020-02-11 The University Of British Columbia Anti-fibrogenic compounds, methods and uses thereof
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane
KR101611349B1 (ko) 2014-04-14 2016-04-12 신우철 안정성이 개선된 밀크씨슬 엑스의 제형
JP7109189B2 (ja) * 2014-05-29 2022-07-29 シャンハイ テックウェル バイオファーマシューティカル カンパニー リミテッド シクロペプチド系化合物の組成物およびその製造方法と使用
AU2015355970B2 (en) * 2014-12-05 2020-05-21 Meiji Seika Pharma Co., Ltd. Method for producing crystals of diazabicyclooctane derivative and stable lyophilized preparation
ES2777942T3 (es) * 2014-12-31 2022-04-22 Galenicum Health S L U Composiciones farmacéuticas estables que comprenden micafungina
ES2694561T3 (es) 2015-02-23 2018-12-21 Selectchemie Ag Composición de anidulafungina
AU2017376960B2 (en) 2016-12-16 2023-12-14 Baxter Healthcare Sa Micafungin compositions
WO2019005829A1 (en) * 2017-06-26 2019-01-03 Wayne State University METHODS AND COMPOSITIONS RELATING TO CANCER DEPENDENT ON HORMONE RECEPTORS
RU2666148C1 (ru) * 2017-10-05 2018-09-06 Общество с ограниченной ответственностью "Новые Антибиотики" Способ получения водорастворимой лиофилизированной формы соли бис(2-тио-4,6-диоксо-1,2,3,4,5,6-гексагидропиримидин-5-ил)-(4-нитрофенил)метана
EP3485873A1 (en) 2017-11-17 2019-05-22 Cadila Healthcare Limited Stable pharmaceutical injectable compositions of micafungin

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AR006598A1 (es) * 1996-04-19 1999-09-08 Merck Sharp & Dohme "composiciones anti-fungosas, su uso en la manufactura de medicamentos y un procedimiento para su preparación"
JPH09301997A (ja) 1996-05-17 1997-11-25 Yamanouchi Pharmaceut Co Ltd 新規環状ペプチド系化合物
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JP3544847B2 (ja) * 1998-01-16 2004-07-21 三菱電機株式会社 光学的情報再生方法および装置
WO2000051564A1 (en) * 1999-03-03 2000-09-08 Eli Lilly And Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
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TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent

Also Published As

Publication number Publication date
AU752265B2 (en) 2002-09-12
PT1107777E (pt) 2005-01-31
CN1315865A (zh) 2001-10-03
DE60015279D1 (de) 2004-12-02
CZ20011186A3 (cs) 2001-09-12
BRPI0006823B1 (pt) 2020-01-07
CA2341568C (en) 2011-10-25
NO330353B1 (no) 2011-04-04
KR100454784B1 (ko) 2004-11-05
HUP0103740A3 (en) 2002-08-28
CN1179748C (zh) 2004-12-15
HU229089B1 (en) 2013-07-29
ES2225161T3 (es) 2005-03-16
IL141455A0 (en) 2002-03-10
TWI233805B (en) 2005-06-11
CA2341568A1 (en) 2001-01-11
JP4691866B2 (ja) 2011-06-01
BR0006823A (pt) 2001-06-05
CZ295720B6 (cs) 2005-10-12
NO20010893D0 (no) 2001-02-22
AU5572200A (en) 2001-01-22
MXPA01000601A (es) 2002-04-08
NO20010893L (no) 2001-04-24
HK1080724A1 (zh) 2006-05-04
ID29468A (id) 2001-08-30
HK1040057A1 (en) 2002-05-24
JP2003503462A (ja) 2003-01-28
US7112565B2 (en) 2006-09-26
OA11601A (en) 2004-07-30
EP1107777B1 (en) 2004-10-27
JP2002363097A (ja) 2002-12-18
IL141455A (en) 2006-12-31
EP1107777A1 (en) 2001-06-20
CN100352495C (zh) 2007-12-05
CN1636591A (zh) 2005-07-13
AR024634A1 (es) 2002-10-16
KR20010072903A (ko) 2001-07-31
HK1040057B (zh) 2005-08-05
PL200141B1 (pl) 2008-12-31
US20040157769A1 (en) 2004-08-12
ATE280583T1 (de) 2004-11-15
US6774104B1 (en) 2004-08-10
TR200100609T1 (tr) 2001-07-23
DE60015279T2 (de) 2005-05-25
PL346297A1 (en) 2002-01-28
WO2001002002A1 (en) 2001-01-11
HUP0103740A2 (hu) 2002-02-28
JP3381722B2 (ja) 2003-03-04
ZA200101589B (en) 2002-09-02
RU2251411C2 (ru) 2005-05-10
NZ510290A (en) 2003-07-25

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