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CL2017000152A1 - Derivados de isoindolinona - Google Patents

Derivados de isoindolinona

Info

Publication number
CL2017000152A1
CL2017000152A1 CL2017000152A CL2017000152A CL2017000152A1 CL 2017000152 A1 CL2017000152 A1 CL 2017000152A1 CL 2017000152 A CL2017000152 A CL 2017000152A CL 2017000152 A CL2017000152 A CL 2017000152A CL 2017000152 A1 CL2017000152 A1 CL 2017000152A1
Authority
CL
Chile
Prior art keywords
isoindolinone derivatives
isoindolinone
derivatives
compounds
understand
Prior art date
Application number
CL2017000152A
Other languages
English (en)
Inventor
Brian Alvin Johns
Emile Johann Velthuisen
Jason Gordon Weatherhead
Original Assignee
Viiv Healthcare Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viiv Healthcare Uk Ltd filed Critical Viiv Healthcare Uk Ltd
Publication of CL2017000152A1 publication Critical patent/CL2017000152A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

<p> </p> <p>SE DAN A CONOCER COMPUESTOS DE LA FÓRMULA I  Y MÉTODOS PARA EL TRATAMIENTO DE INFECCIONES VIRALES CON COMPOSICIONES QUE COMPRENDEN ESTOS COMPUESTOS.</p>
CL2017000152A 2014-07-22 2017-01-19 Derivados de isoindolinona CL2017000152A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462027359P 2014-07-22 2014-07-22

Publications (1)

Publication Number Publication Date
CL2017000152A1 true CL2017000152A1 (es) 2017-07-28

Family

ID=53718075

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017000152A CL2017000152A1 (es) 2014-07-22 2017-01-19 Derivados de isoindolinona

Country Status (17)

Country Link
US (1) US10118894B2 (es)
EP (1) EP3172200B1 (es)
JP (1) JP2017521458A (es)
KR (1) KR20170032338A (es)
CN (1) CN106536513A (es)
AR (1) AR101255A1 (es)
AU (1) AU2015293506B2 (es)
CA (1) CA2954733A1 (es)
CL (1) CL2017000152A1 (es)
ES (1) ES2703352T3 (es)
IL (1) IL249581A0 (es)
PT (1) PT3172200T (es)
RU (1) RU2017103656A (es)
TW (1) TW201617315A (es)
UY (1) UY36221A (es)
WO (1) WO2016012930A1 (es)
ZA (1) ZA201608511B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6579549B2 (ja) 2014-05-16 2019-09-25 塩野義製薬株式会社 Ｈｉｖ複製阻害作用を有する３環性複素環誘導体
MX2017015256A (es) 2015-05-29 2018-02-19 Shionogi & Co Derivados triciclicos que contienen nitrogeno que tienen actividad inhibidora de la replicacion del virus de inmunodeficiencia adquirida (vih).
JP2019522014A (ja) 2016-07-25 2019-08-08 ヴィーブ ヘルスケア ユーケー リミテッド インドリン誘導体
US11396502B2 (en) 2018-11-13 2022-07-26 Incyte Corporation Substituted heterocyclic derivatives as PI3K inhibitors
WO2020102198A1 (en) 2018-11-13 2020-05-22 Incyte Corporation Heterocyclic derivatives as pi3k inhibitors
US11161838B2 (en) 2018-11-13 2021-11-02 Incyte Corporation Heterocyclic derivatives as PI3K inhibitors
CN117320748A (zh) * 2021-03-03 2023-12-29 密苏里大学管委会 Covid-19进入抑制剂对covid-19复制的遏制
CN115160211B (zh) * 2022-06-23 2023-11-03 温州大学 一种异吲哚啉酮类化合物的绿色合成方法
KR20240049492A (ko) 2022-10-08 2024-04-16 임서윤 문어발 건조대

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009026248A2 (en) * 2007-08-17 2009-02-26 The Government Of The United States, As Represented By The Secretary Of Health And Human Services, National Institutes Of Health, Office Of Technology Transfer Hydrazide, amide, phthalimide and phthalhydrazide analogs as inhibitors of retroviral integrase
KR20100097156A (ko) 2007-11-16 2010-09-02 베링거 인겔하임 인터내셔날 게엠베하 사람 면역결핍 바이러스 복제의 억제제
ES2742261T3 (es) * 2011-04-15 2020-02-13 Hivih Inhibidores de la replicación viral, su proceso de preparación y sus usos terapéuticos
US8609653B2 (en) 2011-07-15 2013-12-17 Glaxosmithkline Llc Azaindole compounds and methods for treating HIV
WO2013016441A1 (en) * 2011-07-26 2013-01-31 The United States of America, represented by The Secretary, Department of Health & Human Services Hiv integrase inhibitory oxoisoindoline sulfonamides
WO2013103738A1 (en) * 2012-01-04 2013-07-11 Gilead Sciences, Inc. Napthalene acetic acid derivatives against hiv infection
US9006235B2 (en) * 2012-03-06 2015-04-14 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
RU2014115227A (ru) * 2012-04-20 2015-10-27 Джилид Сайэнс, Инк. Производные бензотиазол-6-ил уксусной кислоты и их примение для лечения вич-инфекции
WO2014009794A1 (en) * 2012-07-12 2014-01-16 Viiv Healthcare Uk Limited Compounds and methods for treating hiv

Also Published As

Publication number Publication date
AU2015293506A1 (en) 2017-01-12
EP3172200A1 (en) 2017-05-31
UY36221A (es) 2016-02-29
TW201617315A (zh) 2016-05-16
CA2954733A1 (en) 2016-01-28
JP2017521458A (ja) 2017-08-03
PT3172200T (pt) 2019-01-17
AR101255A1 (es) 2016-12-07
KR20170032338A (ko) 2017-03-22
IL249581A0 (en) 2017-02-28
WO2016012930A1 (en) 2016-01-28
ZA201608511B (en) 2019-06-26
EP3172200B1 (en) 2018-10-17
AU2015293506B2 (en) 2017-08-17
US20170204058A1 (en) 2017-07-20
US10118894B2 (en) 2018-11-06
RU2017103656A (ru) 2018-08-22
ES2703352T3 (es) 2019-03-08
CN106536513A (zh) 2017-03-22
RU2017103656A3 (es) 2018-11-07

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