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CL2017000152A1 - Isoindolinone derivatives - Google Patents

Isoindolinone derivatives

Info

Publication number
CL2017000152A1
CL2017000152A1 CL2017000152A CL2017000152A CL2017000152A1 CL 2017000152 A1 CL2017000152 A1 CL 2017000152A1 CL 2017000152 A CL2017000152 A CL 2017000152A CL 2017000152 A CL2017000152 A CL 2017000152A CL 2017000152 A1 CL2017000152 A1 CL 2017000152A1
Authority
CL
Chile
Prior art keywords
isoindolinone derivatives
isoindolinone
derivatives
compounds
understand
Prior art date
Application number
CL2017000152A
Other languages
Spanish (es)
Inventor
Brian Alvin Johns
Emile Johann Velthuisen
Jason Gordon Weatherhead
Original Assignee
Viiv Healthcare Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viiv Healthcare Uk Ltd filed Critical Viiv Healthcare Uk Ltd
Publication of CL2017000152A1 publication Critical patent/CL2017000152A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

<p> </p> <p>SE DAN A CONOCER COMPUESTOS DE LA FÓRMULA I  Y MÉTODOS PARA EL TRATAMIENTO DE INFECCIONES VIRALES CON COMPOSICIONES QUE COMPRENDEN ESTOS COMPUESTOS.</p><p> </p> <p> FORMULA I COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS WITH COMPOSITIONS THAT UNDERSTAND THESE COMPOUNDS ARE KNOWN. </p>

CL2017000152A 2014-07-22 2017-01-19 Isoindolinone derivatives CL2017000152A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462027359P 2014-07-22 2014-07-22

Publications (1)

Publication Number Publication Date
CL2017000152A1 true CL2017000152A1 (en) 2017-07-28

Family

ID=53718075

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017000152A CL2017000152A1 (en) 2014-07-22 2017-01-19 Isoindolinone derivatives

Country Status (17)

Country Link
US (1) US10118894B2 (en)
EP (1) EP3172200B1 (en)
JP (1) JP2017521458A (en)
KR (1) KR20170032338A (en)
CN (1) CN106536513A (en)
AR (1) AR101255A1 (en)
AU (1) AU2015293506B2 (en)
CA (1) CA2954733A1 (en)
CL (1) CL2017000152A1 (en)
ES (1) ES2703352T3 (en)
IL (1) IL249581A0 (en)
PT (1) PT3172200T (en)
RU (1) RU2017103656A (en)
TW (1) TW201617315A (en)
UY (1) UY36221A (en)
WO (1) WO2016012930A1 (en)
ZA (1) ZA201608511B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6579549B2 (en) 2014-05-16 2019-09-25 塩野義製薬株式会社 Tricyclic heterocyclic derivatives having HIV replication inhibitory action
MX2017015256A (en) 2015-05-29 2018-02-19 Shionogi & Co Nitrogen-containing tricyclic derivative having hiv replication inhibitory activity.
JP2019522014A (en) 2016-07-25 2019-08-08 ヴィーブ ヘルスケア ユーケー リミテッド Indoline derivative
US11396502B2 (en) 2018-11-13 2022-07-26 Incyte Corporation Substituted heterocyclic derivatives as PI3K inhibitors
WO2020102198A1 (en) 2018-11-13 2020-05-22 Incyte Corporation Heterocyclic derivatives as pi3k inhibitors
US11161838B2 (en) 2018-11-13 2021-11-02 Incyte Corporation Heterocyclic derivatives as PI3K inhibitors
CN117320748A (en) * 2021-03-03 2023-12-29 密苏里大学管委会 Inhibition of copy of COVID-19 by COVID-19 entry inhibitors
CN115160211B (en) * 2022-06-23 2023-11-03 温州大学 Green synthesis method of isoindolinone compound
KR20240049492A (en) 2022-10-08 2024-04-16 임서윤 The drying rack for octopus feet

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009026248A2 (en) * 2007-08-17 2009-02-26 The Government Of The United States, As Represented By The Secretary Of Health And Human Services, National Institutes Of Health, Office Of Technology Transfer Hydrazide, amide, phthalimide and phthalhydrazide analogs as inhibitors of retroviral integrase
KR20100097156A (en) 2007-11-16 2010-09-02 베링거 인겔하임 인터내셔날 게엠베하 Inhibitors of human immunodeficiency virus replication
ES2742261T3 (en) * 2011-04-15 2020-02-13 Hivih Inhibitors of viral replication, its preparation process and its therapeutic uses
US8609653B2 (en) 2011-07-15 2013-12-17 Glaxosmithkline Llc Azaindole compounds and methods for treating HIV
WO2013016441A1 (en) * 2011-07-26 2013-01-31 The United States of America, represented by The Secretary, Department of Health & Human Services Hiv integrase inhibitory oxoisoindoline sulfonamides
WO2013103738A1 (en) * 2012-01-04 2013-07-11 Gilead Sciences, Inc. Napthalene acetic acid derivatives against hiv infection
US9006235B2 (en) * 2012-03-06 2015-04-14 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
RU2014115227A (en) * 2012-04-20 2015-10-27 Джилид Сайэнс, Инк. DERIVATIVES OF BENZOTIAZOL-6-IL ACETIC ACID AND THEIR APPLICATION FOR TREATMENT OF HIV INFECTION
WO2014009794A1 (en) * 2012-07-12 2014-01-16 Viiv Healthcare Uk Limited Compounds and methods for treating hiv

Also Published As

Publication number Publication date
AU2015293506A1 (en) 2017-01-12
EP3172200A1 (en) 2017-05-31
UY36221A (en) 2016-02-29
TW201617315A (en) 2016-05-16
CA2954733A1 (en) 2016-01-28
JP2017521458A (en) 2017-08-03
PT3172200T (en) 2019-01-17
AR101255A1 (en) 2016-12-07
KR20170032338A (en) 2017-03-22
IL249581A0 (en) 2017-02-28
WO2016012930A1 (en) 2016-01-28
ZA201608511B (en) 2019-06-26
EP3172200B1 (en) 2018-10-17
AU2015293506B2 (en) 2017-08-17
US20170204058A1 (en) 2017-07-20
US10118894B2 (en) 2018-11-06
RU2017103656A (en) 2018-08-22
ES2703352T3 (en) 2019-03-08
CN106536513A (en) 2017-03-22
RU2017103656A3 (en) 2018-11-07

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