CL2009000062A1 - Anticuerpo humanizado anti cd79b; con modificaciones de cisterna libre; inmunoconjugado que contiene dicho anticuerpo y una droga; polinucleotido que codifica el anticuerpo; vector, celula huesped; composicion farmaceutica y uso de dicha composicion para tratar cancer, preferentemente linfomas. - Google Patents
Anticuerpo humanizado anti cd79b; con modificaciones de cisterna libre; inmunoconjugado que contiene dicho anticuerpo y una droga; polinucleotido que codifica el anticuerpo; vector, celula huesped; composicion farmaceutica y uso de dicha composicion para tratar cancer, preferentemente linfomas.Info
- Publication number
- CL2009000062A1 CL2009000062A1 CL2009000062A CL2009000062A CL2009000062A1 CL 2009000062 A1 CL2009000062 A1 CL 2009000062A1 CL 2009000062 A CL2009000062 A CL 2009000062A CL 2009000062 A CL2009000062 A CL 2009000062A CL 2009000062 A1 CL2009000062 A1 CL 2009000062A1
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- Prior art keywords
- antibody
- composition
- vector
- host cell
- humanized anti
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
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Abstract
Anticuerpo humanizado anti cd79b; método para obtenerlo; secuencia polipeptídica; polinucleótido que lo codifica; vector que comprende este; célula huésped para dicho vector; inmunoconjugado que contiene dicho anticuerpo; composición farmacéutica y uso de dicha composición para tratar cáncer, método de detección de cd79b.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2513708P | 2008-01-31 | 2008-01-31 | |
| US3279008P | 2008-02-29 | 2008-02-29 | |
| US5470908P | 2008-05-20 | 2008-05-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2009000062A1 true CL2009000062A1 (es) | 2010-05-14 |
Family
ID=40578652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2009000062A CL2009000062A1 (es) | 2008-01-31 | 2009-01-14 | Anticuerpo humanizado anti cd79b; con modificaciones de cisterna libre; inmunoconjugado que contiene dicho anticuerpo y una droga; polinucleotido que codifica el anticuerpo; vector, celula huesped; composicion farmaceutica y uso de dicha composicion para tratar cancer, preferentemente linfomas. |
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| UA (1) | UA106586C2 (es) |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10941199B2 (en) | 2014-12-05 | 2021-03-09 | Genentech, Inc. | Anti-CD79b antibodies and methods of use |
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| US20110045005A1 (en) | 2001-10-19 | 2011-02-24 | Craig Crowley | Compositions and methods for the treatment of tumor of hematopoietic origin |
| US20090068178A1 (en) * | 2002-05-08 | 2009-03-12 | Genentech, Inc. | Compositions and Methods for the Treatment of Tumor of Hematopoietic Origin |
| CA2692819A1 (en) | 2007-07-16 | 2009-01-22 | Genentech, Inc. | Humanized anti-cd79b antibodies and immunoconjugates and methods of use |
| KR101486615B1 (ko) * | 2007-07-16 | 2015-01-28 | 제넨테크, 인크. | 항-cd79b 항체 및 면역접합체 및 사용 방법 |
| EP4427805A3 (en) | 2008-01-31 | 2024-12-18 | Genentech, Inc. | Anti-cd79b antibodies and immunoconjugates and methods of use |
| JP2012531212A (ja) | 2009-07-03 | 2012-12-10 | アビペップ ピーティーワイ リミテッド | イムノコンジュゲート及びその作製方法 |
| AR077756A1 (es) | 2009-07-15 | 2011-09-21 | Genentech Inc | Anticuerpos especificos para bacterias gram-positivas |
| WO2011075786A1 (en) * | 2009-12-23 | 2011-06-30 | Avipep Pty Ltd | Immuno-conjugates and methods for producing them 2 |
| CN106117312A (zh) | 2011-04-21 | 2016-11-16 | 西雅图基因公司 | 新的结合剂‑药物缀合物(adc)及其用途 |
| UY34317A (es) | 2011-09-12 | 2013-02-28 | Genzyme Corp | Anticuerpo antireceptor de célula T (alfa)/ß |
| US8987422B2 (en) | 2011-09-22 | 2015-03-24 | Amgen Inc. | CD27L antigen binding proteins |
| AR091069A1 (es) | 2012-05-18 | 2014-12-30 | Amgen Inc | Proteinas de union a antigeno dirigidas contra el receptor st2 |
| CN102703596B (zh) * | 2012-06-18 | 2013-08-21 | 湖南大学 | 可用于尿酸仪检测目标基因的黄嘌呤氧化酶-dna复合物及其制备方法和在检测中的应用 |
| KR20150023027A (ko) * | 2012-06-19 | 2015-03-04 | 폴리테릭스 리미티드 | 항체 접합체의 제조를 위한 신규한 공정 및 신규한 항체 접합체 |
| KR20150030753A (ko) * | 2012-07-09 | 2015-03-20 | 제넨테크, 인크. | 항-cd79b 항체를 포함하는 면역접합체 |
| US9790268B2 (en) | 2012-09-12 | 2017-10-17 | Genzyme Corporation | Fc containing polypeptides with altered glycosylation and reduced effector function |
| WO2014089177A2 (en) | 2012-12-04 | 2014-06-12 | Massachusetts Institute Of Technology | Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines |
| TW201425336A (zh) | 2012-12-07 | 2014-07-01 | Amgen Inc | Bcma抗原結合蛋白質 |
| ES2728936T3 (es) | 2013-01-25 | 2019-10-29 | Amgen Inc | Anticuerpos dirigidos contra CDH19 para melanoma |
| SG11201506358PA (en) * | 2013-02-15 | 2015-09-29 | Perseus Proteomics Inc | Anti-cdh3 humanized antibody, drug conjugate thereof, and use thereof |
| US9901647B2 (en) | 2013-02-28 | 2018-02-27 | Immunogen, Inc. | Conjugates comprising cell-binding agents and cytotoxic agents |
| EP2983701A2 (en) | 2013-03-11 | 2016-02-17 | Genzyme Corporation | Site-specific antibody-drug conjugation through glycoengineering |
| ES2653424T3 (es) * | 2013-05-02 | 2018-02-07 | F. Hoffmann-La Roche Ag | Tratamiento combinado de un anticuerpo CD20 afucosilado con un conjugado de anticuerpo CD79b y fármaco |
| HUE056580T2 (hu) | 2013-05-30 | 2022-02-28 | Kiniksa Pharmaceuticals Ltd | Onkosztatin-M-receptor antigénjét kötõ fehérjék |
| TW201605896A (zh) | 2013-08-30 | 2016-02-16 | 安美基股份有限公司 | Gitr抗原結合蛋白 |
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| GB201412659D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201412658D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| RU2744978C2 (ru) | 2014-07-24 | 2021-03-17 | Дженентек, Инк. | Способы конъюгации агента с тиольным компонентом в белке, который содержит по меньшей мере одну трисульфидную связь |
| AU2015300080B2 (en) * | 2014-08-06 | 2021-04-01 | Mach5 Therapeutics, Inc. | New anti-human Igbeta antibody |
| HUE049175T2 (hu) * | 2014-09-23 | 2020-09-28 | Hoffmann La Roche | Eljárás anti-CD79b immunkonjugátumok alkalmazására |
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| AU2016278040B2 (en) | 2015-06-16 | 2019-07-04 | Nanophagix LLC | Drug delivery and imaging chemical conjugate, formulations and methods of use thereof |
| WO2017002776A1 (ja) * | 2015-06-29 | 2017-01-05 | 第一三共株式会社 | 抗体-薬物コンジュゲートの選択的製造方法 |
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| EP3356415B1 (en) | 2015-09-29 | 2024-05-01 | Amgen Inc. | Asgr inhibitors for reduzing cholesterol levels |
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| GB201521383D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl And Ucb Celltech | Method |
| JP6788010B2 (ja) * | 2015-12-09 | 2020-11-18 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | インビボ相互作用様式を決定するための方法 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10941199B2 (en) | 2014-12-05 | 2021-03-09 | Genentech, Inc. | Anti-CD79b antibodies and methods of use |
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