CL2007002733A1 - Compuestos derivados de 2-aril-6-fenil-imidazo[1,2-a]piridinas; procedimiento de obtencion de los compuestos; composicion farmaceutica; y uso para el tratamiento y prevencion de enfermedades neurodegenerativas, osteoporosis y cancer. - Google Patents

Compuestos derivados de 2-aril-6-fenil-imidazo[1,2-a]piridinas; procedimiento de obtencion de los compuestos; composicion farmaceutica; y uso para el tratamiento y prevencion de enfermedades neurodegenerativas, osteoporosis y cancer.

Info

Publication number: CL2007002733A1
Authority: CL; Chile
Prior art keywords: compounds; piridines; aril; imidazo; osteoporosis
Prior art date: 2006-09-22

Application number

CL200702733A

Other languages

English (en)

Inventor

Garcia Antonio Lardeno Almario

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-09-22

Filing date

2007-09-21

Publication date

2008-04-11

2007-09-21 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2008-04-11 Publication of CL2007002733A1 publication Critical patent/CL2007002733A1/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Addiction (AREA)
Transplantation (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Epidemiology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CL200702733A 2006-09-22 2007-09-21 Compuestos derivados de 2-aril-6-fenil-imidazo[1,2-a]piridinas; procedimiento de obtencion de los compuestos; composicion farmaceutica; y uso para el tratamiento y prevencion de enfermedades neurodegenerativas, osteoporosis y cancer. CL2007002733A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0608350A FR2906250B1 (fr)	2006-09-22	2006-09-22	Derives de 2-aryl-6phenyl-imidazo(1,2-a) pyridines, leur preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
CL2007002733A1 true CL2007002733A1 (es)	2008-04-11

Family

ID=37841968

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CL200702733A CL2007002733A1 (es)	2006-09-22	2007-09-21	Compuestos derivados de 2-aril-6-fenil-imidazo[1,2-a]piridinas; procedimiento de obtencion de los compuestos; composicion farmaceutica; y uso para el tratamiento y prevencion de enfermedades neurodegenerativas, osteoporosis y cancer.

Country Status (43)

Country	Link
US (1)	US7915284B2 (es)
EP (1)	EP2069342B1 (es)
JP (1)	JP5336378B2 (es)
KR (1)	KR101470039B1 (es)
CN (1)	CN101516881B (es)
AR (1)	AR062897A1 (es)
AT (1)	ATE467633T1 (es)
AU (1)	AU2007298856B2 (es)
BR (1)	BRPI0718517A2 (es)
CA (1)	CA2662848C (es)
CL (1)	CL2007002733A1 (es)
CO (1)	CO6160308A2 (es)
CR (1)	CR10643A (es)
CY (1)	CY1110232T1 (es)
DE (1)	DE602007006525D1 (es)
DK (1)	DK2069342T3 (es)
EA (1)	EA017442B1 (es)
ES (1)	ES2345016T3 (es)
FR (1)	FR2906250B1 (es)
GT (1)	GT200900049A (es)
HN (1)	HN2009000502A (es)
HR (1)	HRP20100408T1 (es)
IL (1)	IL197352A (es)
JO (1)	JO2643B1 (es)
MA (1)	MA30792B1 (es)
ME (1)	ME00615B (es)
MX (1)	MX2009002802A (es)
MY (1)	MY145603A (es)
NI (1)	NI200900037A (es)
NO (1)	NO20091562L (es)
NZ (1)	NZ575337A (es)
PE (1)	PE20080671A1 (es)
PL (1)	PL2069342T3 (es)
PT (1)	PT2069342E (es)
RS (1)	RS51412B (es)
SI (1)	SI2069342T1 (es)
SV (1)	SV2009003193A (es)
TN (1)	TN2009000081A1 (es)
TW (1)	TWI381837B (es)
UA (1)	UA95976C2 (es)
UY (1)	UY30603A1 (es)
WO (1)	WO2008034974A1 (es)
ZA (1)	ZA200901551B (es)

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FR2928924B1 (fr) *	2008-03-21	2010-04-23	Sanofi Aventis	Derives polysubstitues de 6-heteroaryle-imidazo°1,2-a! pyridines, leur preparation et leur application en therapeutique
FR2928923B1 (fr) *	2008-03-21	2010-04-23	Sanofi Aventis	Derives polysubstitues de 2-heteroaryl-6-phenyl-imidazo °1,2-a!pyridines, leur preparation et leur application en therapeutiques
FR2928922B1 (fr) *	2008-03-21	2010-04-23	Sanofi Aventis	Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique
FR2928921B1 (fr)	2008-03-21	2010-04-23	Sanofi Aventis	Derives polysubstitues de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines, leur preparation et leur application en therapeutique
FR2933609B1 (fr)	2008-07-10	2010-08-27	Fournier Lab Sa	Utilisation de derives d'indole comme activateurs de nurr-1, pour le traitement de la maladie de parkinson.
FR2950345B1 (fr) *	2009-09-18	2011-09-23	Sanofi Aventis	Derives acetyleniques de 5-phenyl-pyrazolopyridine, leur preparation et leur application en therapeutique
FR2950344B1 (fr) *	2009-09-18	2011-11-25	Sanofi Aventis	Derives de 5-phenyl-pyrazolopyridine, leur preparation et leur aplication en therapeutique.
FR2953520B1 (fr) *	2009-12-04	2011-11-25	Sanofi Aventis	Derives de diphenyl-pyrazolopyridines, leur preparation et leur application en therapeutique
EP2925756B1 (en) *	2012-11-29	2017-02-01	F. Hoffmann-La Roche AG	Imidazopyridine derivatives
TWI644899B (zh)	2013-02-04	2018-12-21	健生藥品公司	Ｆｌａｐ調節劑
EP3070085B1 (en) *	2013-02-04	2019-01-09	Janssen Pharmaceutica NV	Flap modulators
DK3027615T3 (da) *	2013-08-02	2021-10-25	Pasteur Institut Korea	Antiinfektionsforbindelser
KR20170137165A (ko)	2015-04-10	2017-12-12	베이진 엘티디	인돌아민 및/또는 트립토판 2,3-디옥시게나아제로서 신규한 5 또는 8-치환된 이미다조[1,5-a]피리딘
US20170107216A1 (en)	2015-10-19	2017-04-20	Incyte Corporation	Heterocyclic compounds as immunomodulators
SG11201804152RA (en)	2015-11-19	2018-06-28	Incyte Corp	Heterocyclic compounds as immunomodulators
MA44075A (fr)	2015-12-17	2021-05-19	Incyte Corp	Dérivés de n-phényl-pyridine-2-carboxamide et leur utilisation en tant que modulateurs des interactions protéine/protéine pd-1/pd-l1
EP3828171A1 (en)	2015-12-22	2021-06-02	Incyte Corporation	Heterocyclic compounds as immunomodulators
AR108396A1 (es)	2016-05-06	2018-08-15	Incyte Corp	Compuestos heterocíclicos como inmunomoduladores
TW201808902A (zh)	2016-05-26	2018-03-16	美商英塞特公司	作為免疫調節劑之雜環化合物
AU2017281285C1 (en)	2016-06-20	2022-05-12	Incyte Corporation	Heterocyclic compounds as immunomodulators
EP3484866B1 (en)	2016-07-14	2022-09-07	Incyte Corporation	Heterocyclic compounds as immunomodulators
EP3504198B1 (en)	2016-08-29	2023-01-25	Incyte Corporation	Heterocyclic compounds as immunomodulators
EP3515914A4 (en) *	2016-09-24	2020-04-15	BeiGene, Ltd.	INNOVATIVE 5- OR 8-SUBSTITUTED IMIDAZO [1,5-A] PYRIDINE AS SELECTIVE INHIBITORS OF INDOLEAMINE AND / OR TRYPTOPHANE-2,3-DIOXYGENASES
WO2018119286A1 (en)	2016-12-22	2018-06-28	Incyte Corporation	Bicyclic heteroaromatic compounds as immunomodulators
PE20200005A1 (es)	2016-12-22	2020-01-06	Incyte Corp	Derivados de tetrahidro imidazo[4,5-c]piridina como inductores de internalizacion pd-l1
IL295660A (en)	2016-12-22	2022-10-01	Incyte Corp	Benzooxazole derivatives as immunomodulators
EP3558989B1 (en)	2016-12-22	2021-04-14	Incyte Corporation	Triazolo[1,5-a]pyridine derivatives as immunomodulators
US20180179179A1 (en)	2016-12-22	2018-06-28	Incyte Corporation	Heterocyclic compounds as immunomodulators
WO2019101188A1 (en)	2017-11-25	2019-05-31	Beigene, Ltd.	Novel benzoimidazoles as selective inhibitors of indoleamine 2, 3-dioxygenases
KR20250067967A (ko)	2018-03-30	2025-05-15	인사이트 코포레이션	면역조절제로서 복소환형 화합물
HUE061503T2 (hu)	2018-05-11	2023-07-28	Incyte Corp	Tetrahidro-imidazo[4,5-C]piridin-származékok mint PD-L1 immunmodulátorok
EP4010342A1 (en)	2019-08-09	2022-06-15	Incyte Corporation	Salts of a pd-1/pd-l1 inhibitor
TWI879811B (zh)	2019-09-30	2025-04-11	美商英塞特公司	作為免疫調節劑之吡啶并[3,2-d]嘧啶化合物
PH12022551136A1 (en)	2019-11-11	2023-10-09	Incyte Corp	Salts and crystalline forms of a pd-1/pd-l1 inhibitor
TWI759962B (zh) *	2019-11-13	2022-04-01	香港商新旭生技股份有限公司	用於降解tau蛋白聚集體的化合物及其用途
TW202233615A (zh)	2020-11-06	2022-09-01	美商英塞特公司	Ｐｄ—１／ｐｄ—ｌ１抑制劑之結晶形式
US11780836B2 (en)	2020-11-06	2023-10-10	Incyte Corporation	Process of preparing a PD-1/PD-L1 inhibitor
CN116670114A (zh)	2020-11-06	2023-08-29	因赛特公司	用于制备pd-1/pd-l1抑制剂以及其盐和结晶形式的方法

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WO2004026867A2 (en) *	2002-09-19	2004-04-01	Schering Corporation	Imidazopyridines as cyclin dependent kinase inhibitors
GB0303503D0 (en) *	2003-02-14	2003-03-19	Novartis Ag	Organic compounds
JP2007527908A (ja) *	2004-03-08	2007-10-04	ザユニバーシティオブノースカロライナアットチャペルヒル	抗原虫薬としての新規ジカチオン性イミダゾ［１，２−ａ］ピリジン、及び５，６，７，８−テトラヒドロ−イミダゾ［１，２−ａ］ピリジン

2006
- 2006-09-22 FR FR0608350A patent/FR2906250B1/fr active Active
2007
- 2007-09-13 TW TW096134253A patent/TWI381837B/zh not_active IP Right Cessation
- 2007-09-19 PL PL07848251T patent/PL2069342T3/pl unknown
- 2007-09-19 NZ NZ575337A patent/NZ575337A/en not_active IP Right Cessation
- 2007-09-19 RS RSP-2010/0356A patent/RS51412B/sr unknown
- 2007-09-19 MY MYPI20091157A patent/MY145603A/en unknown
- 2007-09-19 AR ARP070104136A patent/AR062897A1/es not_active Application Discontinuation
- 2007-09-19 CA CA2662848A patent/CA2662848C/fr not_active Expired - Fee Related
- 2007-09-19 AT AT07848251T patent/ATE467633T1/de active
- 2007-09-19 AU AU2007298856A patent/AU2007298856B2/en not_active Ceased
- 2007-09-19 UA UAA200903928A patent/UA95976C2/ru unknown
- 2007-09-19 ZA ZA200901551A patent/ZA200901551B/xx unknown
- 2007-09-19 BR BRPI0718517-0A patent/BRPI0718517A2/pt active Search and Examination
- 2007-09-19 HR HR20100408T patent/HRP20100408T1/hr unknown
- 2007-09-19 WO PCT/FR2007/001517 patent/WO2008034974A1/fr not_active Ceased
- 2007-09-19 DE DE602007006525T patent/DE602007006525D1/de active Active
- 2007-09-19 DK DK07848251.0T patent/DK2069342T3/da active
- 2007-09-19 KR KR1020097005741A patent/KR101470039B1/ko not_active Expired - Fee Related
- 2007-09-19 MX MX2009002802A patent/MX2009002802A/es active IP Right Grant
- 2007-09-19 CN CN2007800352403A patent/CN101516881B/zh not_active Expired - Fee Related
- 2007-09-19 ME MEP-2009-107A patent/ME00615B/me unknown
- 2007-09-19 SI SI200730316T patent/SI2069342T1/sl unknown
- 2007-09-19 EP EP07848251A patent/EP2069342B1/fr active Active
- 2007-09-19 ES ES07848251T patent/ES2345016T3/es active Active
- 2007-09-19 EA EA200970311A patent/EA017442B1/ru not_active IP Right Cessation
- 2007-09-19 JP JP2009528752A patent/JP5336378B2/ja not_active Expired - Fee Related
- 2007-09-19 PT PT07848251T patent/PT2069342E/pt unknown
- 2007-09-20 PE PE2007001266A patent/PE20080671A1/es not_active Application Discontinuation
- 2007-09-20 JO JO2007401A patent/JO2643B1/en active
- 2007-09-21 CL CL200702733A patent/CL2007002733A1/es unknown
- 2007-09-21 UY UY30603A patent/UY30603A1/es not_active Application Discontinuation
2009
- 2009-02-26 CR CR10643A patent/CR10643A/es unknown
- 2009-03-02 IL IL197352A patent/IL197352A/en not_active IP Right Cessation
- 2009-03-05 GT GT200900049A patent/GT200900049A/es unknown
- 2009-03-10 TN TN2009000081A patent/TN2009000081A1/fr unknown
- 2009-03-18 HN HN2009000502A patent/HN2009000502A/es unknown
- 2009-03-19 SV SV2009003193A patent/SV2009003193A/es active IP Right Grant
- 2009-03-19 NI NI200900037A patent/NI200900037A/es unknown
- 2009-03-19 US US12/407,449 patent/US7915284B2/en not_active Expired - Fee Related
- 2009-03-19 CO CO09028759A patent/CO6160308A2/es unknown
- 2009-04-16 MA MA31788A patent/MA30792B1/fr unknown
- 2009-04-20 NO NO20091562A patent/NO20091562L/no not_active Application Discontinuation
2010
- 2010-07-20 CY CY20101100678T patent/CY1110232T1/el unknown

Also Published As

Publication number	Publication date
MEP10709A (en)	2011-12-20
CN101516881B (zh)	2012-07-18
TW200833329A (en)	2008-08-16
JP5336378B2 (ja)	2013-11-06
CA2662848C (fr)	2014-12-23
DK2069342T3 (da)	2010-08-23
HRP20100408T1 (hr)	2010-09-30
RS51412B (sr)	2011-02-28
KR101470039B1 (ko)	2014-12-05
FR2906250B1 (fr)	2008-10-31
NO20091562L (no)	2009-04-20
CY1110232T1 (el)	2015-01-14
AR062897A1 (es)	2008-12-10
UA95976C2 (en)	2011-09-26
EA017442B1 (ru)	2012-12-28
MY145603A (en)	2012-03-15
JO2643B1 (en)	2012-06-17
US20090253735A1 (en)	2009-10-08
GT200900049A (es)	2010-03-04
EA200970311A1 (ru)	2009-08-28
PL2069342T3 (pl)	2010-10-29
ZA200901551B (en)	2010-06-30
NI200900037A (es)	2014-02-20
ATE467633T1 (de)	2010-05-15
KR20090054449A (ko)	2009-05-29
IL197352A0 (en)	2009-12-24
US7915284B2 (en)	2011-03-29
HN2009000502A (es)	2011-07-11
HK1135388A1 (en)	2010-06-04
CA2662848A1 (fr)	2008-03-27
FR2906250A1 (fr)	2008-03-28
TN2009000081A1 (en)	2010-08-19
NZ575337A (en)	2011-12-22
TWI381837B (zh)	2013-01-11
DE602007006525D1 (de)	2010-06-24
SV2009003193A (es)	2010-02-01
PT2069342E (pt)	2010-07-19
JP2010504309A (ja)	2010-02-12
CO6160308A2 (es)	2010-05-20
EP2069342A1 (fr)	2009-06-17
IL197352A (en)	2014-11-30
MA30792B1 (fr)	2009-10-01
MX2009002802A (es)	2009-04-01
ME00615B (me)	2011-12-20
SI2069342T1 (sl)	2010-09-30
WO2008034974A1 (fr)	2008-03-27
CN101516881A (zh)	2009-08-26
BRPI0718517A2 (pt)	2013-11-19
AU2007298856A1 (en)	2008-03-27
AU2007298856B2 (en)	2012-08-09
UY30603A1 (es)	2008-05-02
EP2069342B1 (fr)	2010-05-12
ES2345016T3 (es)	2010-09-13
CR10643A (es)	2009-04-29
PE20080671A1 (es)	2008-07-14

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