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CL2008002295A1 - Compuestos derivados de tiazolida sustituidos con alquilsulfonilos; composicion farmaceutica; y uso para el tratamiento de la hepatitis c. - Google Patents

Compuestos derivados de tiazolida sustituidos con alquilsulfonilos; composicion farmaceutica; y uso para el tratamiento de la hepatitis c.

Info

Publication number
CL2008002295A1
CL2008002295A1 CL2008002295A CL2008002295A CL2008002295A1 CL 2008002295 A1 CL2008002295 A1 CL 2008002295A1 CL 2008002295 A CL2008002295 A CL 2008002295A CL 2008002295 A CL2008002295 A CL 2008002295A CL 2008002295 A1 CL2008002295 A1 CL 2008002295A1
Authority
CL
Chile
Prior art keywords
thiazolid
alkylsulfonyl
hepatitis
substituted
treatment
Prior art date
Application number
CL2008002295A
Other languages
English (en)
Inventor
Jean-Francois Rossignol
J Edward Semple
Original Assignee
Romark Laboratories Lc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39791394&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2008002295(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Romark Laboratories Lc filed Critical Romark Laboratories Lc
Publication of CL2008002295A1 publication Critical patent/CL2008002295A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

Compuestos derivados de tiazolida sustituidos con alquilsulfonilos; composición farmacéutica; y uso para el tratamiento de la hepatitis C.
CL2008002295A 2007-08-03 2008-08-04 Compuestos derivados de tiazolida sustituidos con alquilsulfonilos; composicion farmaceutica; y uso para el tratamiento de la hepatitis c. CL2008002295A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95375807P 2007-08-03 2007-08-03
US4695608P 2008-04-22 2008-04-22
US5636908P 2008-05-27 2008-05-27

Publications (1)

Publication Number Publication Date
CL2008002295A1 true CL2008002295A1 (es) 2009-03-27

Family

ID=39791394

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008002295A CL2008002295A1 (es) 2007-08-03 2008-08-04 Compuestos derivados de tiazolida sustituidos con alquilsulfonilos; composicion farmaceutica; y uso para el tratamiento de la hepatitis c.

Country Status (15)

Country Link
US (2) US8124632B2 (es)
EP (1) EP2178852B9 (es)
JP (1) JP5676258B2 (es)
CN (1) CN101835765B (es)
AR (1) AR068334A1 (es)
AU (1) AU2008299781B2 (es)
BR (1) BRPI0815057B8 (es)
CA (1) CA2695517C (es)
CL (1) CL2008002295A1 (es)
EA (1) EA019357B1 (es)
ES (1) ES2550755T3 (es)
MX (1) MX2010001358A (es)
PT (1) PT2178852E (es)
TW (1) TWI453018B (es)
WO (1) WO2009035788A1 (es)

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MX341877B (es) * 2009-06-26 2016-09-06 Romark Laboratories L C * Compuestos y métodos para tratar influenza.
US9333193B2 (en) 2010-09-20 2016-05-10 University Of Virginia Patent Foundation Compositions and methods for treating tuberculosis
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EP3436074B1 (en) 2016-03-31 2020-06-10 Romark Laboratories, L.C. Thiazolide compounds for treating viral infections
DK3777855T3 (da) 2016-04-11 2023-01-09 Genfit Fremgangsmåder til behandling af fibrotiske sygdomme
CN106565626B (zh) * 2016-10-10 2022-06-10 淮海工学院 2-氨基-4-芳基-5-甲硫基噻唑类化合物的合成方法
CN108610301B (zh) * 2016-12-12 2021-08-31 中山大学 一类手性芳杂胺类衍生物及其合成方法和应用
WO2018107332A1 (zh) * 2016-12-12 2018-06-21 中山大学 一类手性芳杂胺类衍生物及其合成方法和应用
WO2018195035A1 (en) 2017-04-18 2018-10-25 Romark Laboratories L.C. Inhibition of protein disulfide-isomerase a3
WO2019241376A1 (en) 2018-06-14 2019-12-19 The Trustees Of Columbia University In The City Of New York Treatment of cognitive disorders using nitazoxanide (ntz), nitazoxanide (ntz) analogs, and metabolites thereof
CN111848601B (zh) * 2019-04-30 2022-06-21 南京海璞医药科技有限公司 一种含稠环的化合物、其应用及含其的药物组合物
CN118978524A (zh) * 2019-09-11 2024-11-19 绍兴君科臻元医药科技有限公司 硝唑尼特衍生物及其医药用途
US20230140290A1 (en) * 2020-01-26 2023-05-04 The Board Of Regents Of The University Of Texas Sy Salicylamide derivatives and related methods of making
CA3186666A1 (en) 2020-07-20 2022-01-27 Jean-Francois Rossignol Crystalline salts of tizoxanide and 2-hydroxy-n-(5-chloro-1,3-thiazol-2-yl)benzamide (rm-4848) with ethanolamine, morpholine, propanolamine, piperazine and n-methylpiperazine
US20230330069A1 (en) 2020-08-24 2023-10-19 Romark Laboratories, L.C. Use of thiazolides against coronaviruses
US12274700B1 (en) 2020-10-30 2025-04-15 Accencio LLC Methods of treating symptoms of coronavirus infection with RNA polymerase inhibitors
EP4448492A1 (en) 2021-12-17 2024-10-23 Reglagene, Inc. Compositions and methods of making and using small molecules in the treatment of cancer
KR20250176573A (ko) 2023-02-28 2025-12-19 레글라진, 아이엔씨. 건강 상태의 치료를 위한 소분자 제조 및 사용을 위한 조성물 및 방법

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Also Published As

Publication number Publication date
CA2695517C (en) 2016-09-20
HK1147094A1 (en) 2011-07-29
US20120122939A1 (en) 2012-05-17
BRPI0815057A2 (pt) 2015-07-28
EP2178852A1 (en) 2010-04-28
US8124632B2 (en) 2012-02-28
MX2010001358A (es) 2010-04-09
EP2178852B9 (en) 2016-06-22
CA2695517A1 (en) 2009-03-19
US20090036467A1 (en) 2009-02-05
AU2008299781A1 (en) 2009-03-19
TWI453018B (zh) 2014-09-21
TW200911239A (en) 2009-03-16
CN101835765B (zh) 2013-05-29
ES2550755T3 (es) 2015-11-12
EP2178852B1 (en) 2015-07-22
BRPI0815057B1 (pt) 2020-11-10
AR068334A1 (es) 2009-11-11
EA201070182A1 (ru) 2010-10-29
US8895752B2 (en) 2014-11-25
AU2008299781B2 (en) 2013-11-14
CN101835765A (zh) 2010-09-15
JP2010535712A (ja) 2010-11-25
JP5676258B2 (ja) 2015-02-25
PT2178852E (pt) 2015-11-12
BRPI0815057B8 (pt) 2021-05-25
WO2009035788A1 (en) 2009-03-19
EA019357B1 (ru) 2014-03-31

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