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BRPI0818528A8 - Aumento do rendimento da metionina - Google Patents

Aumento do rendimento da metionina

Info

Publication number
BRPI0818528A8
BRPI0818528A8 BRPI0818528A BRPI0818528A BRPI0818528A8 BR PI0818528 A8 BRPI0818528 A8 BR PI0818528A8 BR PI0818528 A BRPI0818528 A BR PI0818528A BR PI0818528 A BRPI0818528 A BR PI0818528A BR PI0818528 A8 BRPI0818528 A8 BR PI0818528A8
Authority
BR
Brazil
Prior art keywords
methionine
increase
yield
microorganism
derivatives
Prior art date
Application number
BRPI0818528A
Other languages
English (en)
Inventor
Figge Rainer
Barbier Guillaume
Boisart Cédric
Chateau Michel
Bestel-Corre Gwénaëlle
Soucaille Philippe
Original Assignee
Metabolic Explorer Sa
Evonik Degussa Gmbh
Evonik Operations Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolic Explorer Sa, Evonik Degussa Gmbh, Evonik Operations Gmbh filed Critical Metabolic Explorer Sa
Publication of BRPI0818528A2 publication Critical patent/BRPI0818528A2/pt
Publication of BRPI0818528A8 publication Critical patent/BRPI0818528A8/pt
Publication of BRPI0818528B1 publication Critical patent/BRPI0818528B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/12Methionine; Cysteine; Cystine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y305/00Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/0101Formyltetrahydrofolate deformylase (3.5.1.10)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

AUMENTO DO RENDIMENTO DA METIONINA. A presente invenção se refere a um processo pra a produção de metionina e seus derivados pelo cultivo de um microrganismo em um meio de cultura apropriado compreendendo uma fonte de carbono e uma fonte de enxofre. O microrganismo e/ou o meio de cultura são modificados de tal forma que o rendimento de metionina/fone de carbono é aumentado. O isolamento da metionina ou seus derivados do meio de fermentação também é descrito.
BRPI0818528-0A 2007-10-02 2008-09-25 Aumento do rendimento da metionina BRPI0818528B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/EP2007/060433 WO2009043372A1 (en) 2007-10-02 2007-10-02 Increasing methionine yield
EPPCT/EP2007/060433 2007-10-02
PCT/EP2008/062859 WO2009043803A2 (en) 2007-10-02 2008-09-25 Increasing methionine yield

Publications (3)

Publication Number Publication Date
BRPI0818528A2 BRPI0818528A2 (pt) 2016-07-26
BRPI0818528A8 true BRPI0818528A8 (pt) 2017-09-19
BRPI0818528B1 BRPI0818528B1 (pt) 2023-01-17

Family

ID=39521485

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0818528-0A BRPI0818528B1 (pt) 2007-10-02 2008-09-25 Aumento do rendimento da metionina

Country Status (16)

Country Link
US (2) US20100248311A1 (pt)
EP (2) EP2205754B1 (pt)
JP (1) JP5701604B2 (pt)
KR (2) KR101586098B1 (pt)
CN (2) CN103087971B (pt)
AR (1) AR068722A1 (pt)
BR (1) BRPI0818528B1 (pt)
DK (2) DK2205754T3 (pt)
ES (2) ES2557487T3 (pt)
HR (1) HRP20160075T1 (pt)
HU (2) HUE030032T2 (pt)
MX (1) MX2010003609A (pt)
MY (2) MY170749A (pt)
PL (2) PL2573189T3 (pt)
RU (1) RU2010115225A (pt)
WO (2) WO2009043372A1 (pt)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4110641B2 (ja) 1998-11-17 2008-07-02 味の素株式会社 発酵法によるl−メチオニンの製造法
EP2121954A2 (en) * 2007-02-19 2009-11-25 Evonik Degussa GmbH Coryneform bacteria with formate-thf-synthetase and/or glycine cleavage activity
WO2010020290A1 (en) 2008-08-22 2010-02-25 Metabolic Explorer Producing methionine without n-acetyl methionine
WO2010020289A1 (en) 2008-08-22 2010-02-25 Metabolic Explorer Production of n-acetylated sulphur-containing amino acids with microorganisms having enhanced n-acetyltransferase enzymatic activity
DE102009030342A1 (de) 2009-06-25 2010-12-30 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen
FR2951195B1 (fr) 2009-10-14 2014-01-31 Roquette Freres Composition riche en methionine destinee a l'alimentation animale
CN102666838B (zh) 2009-11-18 2018-04-10 麦兰特公司 用于高效产生化学品的工程化微生物
WO2011073738A1 (en) * 2009-12-14 2011-06-23 Metabolic Explorer Use of inducible promoters in the production of methionine
KR101770123B1 (ko) 2009-12-30 2017-08-23 에보니크 데구사 게엠베하 숙시네이트 데히드로게나제의 과다발현에 의한 메티오닌 생산의 증가
CN102782137B (zh) 2009-12-30 2016-01-06 代谢探索者公司 用于甲硫氨酸生产的菌株和方法
AR083468A1 (es) * 2010-10-25 2013-02-27 Metabolic Explorer Sa Aumento de la disponibilidad de nadph para la produccion de metionina
WO2012090021A1 (en) 2010-12-30 2012-07-05 Metabolic Explorer Recombinant microorganism for the fermentative production of methionine
EP2658987B1 (en) 2010-12-30 2014-12-10 Metabolic Explorer Fermentative production of methionine hydroxy analog (mha)
EP2479279A1 (de) 2011-01-20 2012-07-25 Evonik Degussa GmbH Verfahren zur fermentativen Herstellung schwefelhaltiger Aminosäuren
WO2012137689A1 (ja) 2011-04-01 2012-10-11 味の素株式会社 L-システインの製造法
US9234223B2 (en) 2011-04-01 2016-01-12 Ajinomoto Co., Inc. Method for producing L-cysteine
DE102011006716A1 (de) 2011-04-04 2012-10-04 Evonik Degussa Gmbh Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung
DE102011118019A1 (de) 2011-06-28 2013-01-03 Evonik Degussa Gmbh Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens
AR086790A1 (es) * 2011-06-29 2014-01-22 Metabolic Explorer Sa Un microorganismo para la produccion de metionina con importacion de glucosa mejorada
FR2983870B1 (fr) 2011-12-08 2015-07-17 Roquette Freres Composition en methionine destinee a l'alimentation animale
EP2628792A1 (de) 2012-02-17 2013-08-21 Evonik Industries AG Zelle mit verringerter ppGppase-Aktivität
US9347048B2 (en) 2012-04-27 2016-05-24 Evonik Technochemie Gmbh Feedback-resistant alpha-isopropylmalate synthases
EP2861726B1 (en) 2012-06-18 2017-05-31 Evonik Degussa GmbH Recombinant microorganism for the fermentative production of methionine
PL2700715T3 (pl) 2012-08-20 2019-03-29 Evonik Degussa Gmbh Sposób fermentacyjnego wytwarzania L-aminokwasów z zastosowaniem ulepszonych szczepów z rodziny Enterobacteriaceae
WO2014049382A2 (en) 2012-09-26 2014-04-03 Metabolic Explorer Ethylenediamine fermentative production by a recombinant microorganism
DE102012024435A1 (de) 2012-12-14 2014-07-10 Forschungszentrum Jülich GmbH Verfahren zur Identifizierung einer Zelle mit gegenüber ihrem Wildtyp erhöhten intrazellulären Konzentration eines bestimmten Metaboliten, wobei die Veränderung der Zelle durch Rekombi-neering erreicht wird, sowie ein Verfahren zur Herstellung einer gegenüber ihrem Wildtyp genetisch veränderten Produktionszelle mit optimierter Produktion eines bestimmten Metaboliten, ein Verfahren zur Herstellung dieses Metaboliten, sowie dafür geeignete Nukleinsäuren
EP2762571A1 (de) 2013-01-30 2014-08-06 Evonik Industries AG Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren
HUE032752T2 (en) 2013-06-03 2017-10-30 Evonik Degussa Gmbh A method for the preparation of L-valine using recombinant corynebacteria containing propionate-inducible ilvBN operon
BR112016004367B1 (pt) 2013-08-30 2022-06-14 Evonik Operations Gmbh Microrganismo recombinante e método para a produção fermentativa de metionina e/ou seus derivados
EP2940039A1 (de) * 2014-04-30 2015-11-04 Evonik Degussa GmbH Verfahren zur Produktion von L-Aminosäuren in Corynebakterien unter Verwendung eines Glycin spaltenden Systems
CN103981206B (zh) * 2014-06-06 2016-03-02 中国科学院天津工业生物技术研究所 一种筛选高产苏氨酸菌株的方法
WO2016034536A1 (en) * 2014-09-01 2016-03-10 Metabolic Explorer Method and microorganism for methionine production by fermentation with improved methionine efflux
CA2978228A1 (en) * 2015-03-18 2016-09-22 Basf Se Recombinant microorganism for improved production of fine chemicals
ES2811337T3 (es) 2015-04-07 2021-03-11 Metabolic Explorer Sa Microorganismo modificado para la producción optimizada de 2,4-dihidroxibutirato con eflujo de 2,4- dihidroxibutirato aumentado
CN108026516A (zh) * 2015-08-07 2018-05-11 赢创德固赛有限公司 通过发酵的蛋白硫代羧化物依赖性l-甲硫氨酸生产
FR3041658B1 (fr) 2015-09-30 2017-10-20 Arkema France Procede de production de l-methionine
FR3041659B1 (fr) 2015-09-30 2017-10-20 Arkema France Procede de production de l-methionine
MY186059A (en) 2015-11-27 2021-06-17 Evonik Operations Gmbh Method for producing l-methionine
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
BR112018011503A2 (pt) 2015-12-07 2018-12-04 Zymergen Inc promotores da corynebacterium glutamicum
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
CN108603207A (zh) 2016-01-08 2018-09-28 赢创德固赛有限公司 通过发酵生产来生产l-甲硫氨酸的方法
WO2018005793A1 (en) 2016-06-30 2018-01-04 Zymergen Inc. Methods for generating a glucose permease library and uses thereof
KR102345899B1 (ko) 2016-06-30 2021-12-31 지머젠 인코포레이티드 박테리아 헤모글로빈 라이브러리를 생성하는 방법 및 이의 용도
EP3296404A1 (en) 2016-09-15 2018-03-21 Evonik Degussa GmbH Modified microorganism for production of methionine
US11560584B2 (en) 2016-12-30 2023-01-24 Quidel Corporation Phage-mediated immunoassay and methods for determining susceptibility of bacteria to antibiotic or probiotic agents
EP3354742A1 (en) 2017-01-26 2018-08-01 Metabolic Explorer Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid
US20200239897A1 (en) 2017-06-07 2020-07-30 Zymergen Inc. Promoters from corynebacterium glutamicum and uses thereof in regulating ancillary gene expression
JP2020526205A (ja) 2017-07-11 2020-08-31 アディッソ・フランス・エス.エー.エス.Adisseo France S.A.S. メチオニン生産酵母
WO2019070612A1 (en) 2017-10-02 2019-04-11 Quidel Corporation PHAGE-BASED DETECTION METHOD FOR ANTIMICROBIAL SUSCEPTIBILITY TESTING AND IDENTIFICATION OF BACTERIAL SPECIES
CN109055289B (zh) * 2018-07-27 2020-10-27 浙江工业大学 一种高产l-甲硫氨酸的重组大肠杆菌及其应用
CN109652351B (zh) * 2018-12-18 2020-08-04 江南大学 一种高产5-甲基四氢叶酸重组枯草芽孢杆菌及其应用
CN113388630B (zh) * 2020-03-11 2022-07-26 华东理工大学 合成l-半胱氨酸的重组大肠杆菌的构建方法及其应用
CN116249778A (zh) 2020-07-15 2023-06-09 赢创运营有限公司 编码氨基酸序列、编码氧化还原酶的多核苷酸
CN112779200B (zh) * 2021-01-12 2022-07-08 浙江工业大学 高产l-甲硫氨酸的基因工程菌及其构建与应用
EP4384537A1 (en) 2021-08-09 2024-06-19 Evonik Operations GmbH Method for producing a recombinant bacterial collagen-like protein (clp)
EP4384539A1 (en) 2021-08-09 2024-06-19 Evonik Operations GmbH Polynucleotide encoding a bacterial collagen-like protein
CN117813315A (zh) 2021-08-09 2024-04-02 赢创运营有限公司 用于生产重组细菌胶原样蛋白(clp)的方法
EP4404988B1 (en) 2021-09-20 2025-10-29 Evonik Operations GmbH Non-adhesive collagen-like hydrogels
EP4482541A1 (en) 2022-02-25 2025-01-01 Evonik Operations GmbH Sponges based on collagen-like proteins
WO2023165952A1 (en) 2022-03-01 2023-09-07 Evonik Operations Gmbh Biotechnological production of collagen proteins and bacterial collagen-like proteins by recombinant microorganisms
CN121263216A (zh) 2023-06-06 2026-01-02 赢创运营有限公司 由胶原样蛋白(clp)制备的水凝胶贴剂
CN116590209A (zh) 2023-06-13 2023-08-15 浙江工业大学 一种产d-泛酸的基因工程菌、构建方法及应用
WO2025016819A1 (en) 2023-07-20 2025-01-23 Evonik Operations Gmbh Sponge comprising a recombinant collagen-like peptide (clp) and bioactive glass
WO2025186007A1 (en) 2024-03-08 2025-09-12 Evonik Operations Gmbh Collagen-like protein coated medical devices and coating method thereof
WO2025217267A1 (en) * 2024-04-11 2025-10-16 Natáur Inc. Platform for bio-based production of high levels of o-phosphoserine, cysteate or taurine

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0796916A1 (en) * 1996-03-22 1997-09-24 Triple-A B.V. Improvement of amino acid fermentation processes
JP3207746B2 (ja) 1996-03-25 2001-09-10 シャープ株式会社 ファクシミリ装置
GB9724627D0 (en) * 1997-11-20 1998-01-21 Genencor Int Bv Gram positive microorganism formate pathway
JP2000157267A (ja) 1998-11-24 2000-06-13 Ajinomoto Co Inc 変異型metJ遺伝子及びL−メチオニンの製造法
WO2004076659A2 (fr) 2003-02-18 2004-09-10 Metabolic Explorer Procede de preparation de microorganismes evolues permettant la creation ou la modification de voies metaboliques
KR100488463B1 (ko) 2003-07-24 2005-05-11 엘지전자 주식회사 플라즈마 디스플레이 패널의 구동장치 및 방법
WO2005111202A1 (en) 2004-05-12 2005-11-24 Metabolic Explorer Recombinant enzyme with altered feedback sensitivity
KR100651220B1 (ko) 2004-06-29 2006-11-29 씨제이 주식회사 L-메씨오닌 생산 균주 및 상기 균주를 이용한l-메씨오닌의 생산방법
KR100656590B1 (ko) * 2004-07-30 2006-12-11 한국과학기술원 박테리아 변이균주 및 이를 이용한 숙신산 및 아미노산의제조방법
JP2008529485A (ja) * 2005-02-07 2008-08-07 メタボリック エクスプローラー 低いγ脱離活性を有する発現酵素を含む微生物
KR20080036608A (ko) 2005-07-18 2008-04-28 바스프 에스이 메티오닌 생산 재조합 미생물
CA2620468A1 (en) * 2005-08-18 2007-02-22 Basf Aktiengesellschaft Microorganisms with increased efficiency for methionine synthesis
CN101291590A (zh) 2005-10-31 2008-10-22 巴斯夫欧洲公司 用于制备l-甲硫氨酸的微生物和方法
US8389250B2 (en) * 2006-01-04 2013-03-05 Metabolic Explorer Methods for producing methionine by culturing a microorganism modified to enhance production of cysteine
EP2121954A2 (en) * 2007-02-19 2009-11-25 Evonik Degussa GmbH Coryneform bacteria with formate-thf-synthetase and/or glycine cleavage activity

Also Published As

Publication number Publication date
WO2009043803A3 (en) 2009-06-18
WO2009043372A1 (en) 2009-04-09
HUE026672T2 (en) 2016-07-28
JP2010539962A (ja) 2010-12-24
US20100248311A1 (en) 2010-09-30
KR101586098B1 (ko) 2016-01-19
CN103087971A (zh) 2013-05-08
DK2573189T3 (en) 2016-09-26
HUE030032T2 (en) 2017-04-28
ES2557487T3 (es) 2016-01-26
RU2010115225A (ru) 2011-11-10
KR20100075587A (ko) 2010-07-02
JP5701604B2 (ja) 2015-04-15
EP2205754A2 (en) 2010-07-14
KR101636662B1 (ko) 2016-07-05
MY170749A (en) 2019-08-27
MY180720A (en) 2020-12-07
BRPI0818528B1 (pt) 2023-01-17
KR20150038696A (ko) 2015-04-08
BRPI0818528A2 (pt) 2016-07-26
CN103087971B (zh) 2016-12-28
PL2573189T3 (pl) 2017-01-31
HRP20160075T1 (hr) 2016-02-12
DK2205754T3 (en) 2015-12-21
ES2600036T3 (es) 2017-02-06
MX2010003609A (es) 2010-04-30
PL2205754T3 (pl) 2016-04-29
EP2573189B1 (en) 2016-08-03
EP2205754B1 (en) 2015-11-04
US10858679B2 (en) 2020-12-08
EP2573189A1 (en) 2013-03-27
WO2009043803A2 (en) 2009-04-09
CN101821401B (zh) 2013-10-30
US20160160249A1 (en) 2016-06-09
CN101821401A (zh) 2010-09-01
AR068722A1 (es) 2009-12-02

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