BRPI0818528A2 - aumento de rendimento da metionina - Google Patents
aumento de rendimento da metioninaInfo
- Publication number
- BRPI0818528A2 BRPI0818528A2 BRPI0818528A BRPI0818528A BRPI0818528A2 BR PI0818528 A2 BRPI0818528 A2 BR PI0818528A2 BR PI0818528 A BRPI0818528 A BR PI0818528A BR PI0818528 A BRPI0818528 A BR PI0818528A BR PI0818528 A2 BRPI0818528 A2 BR PI0818528A2
- Authority
- BR
- Brazil
- Prior art keywords
- increased methionine
- methionine yield
- yield
- increased
- methionine
- Prior art date
Links
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 title 1
- 229930182817 methionine Natural products 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
- C12Y305/0101—Formyltetrahydrofolate deformylase (3.5.1.10)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2007/060433 WO2009043372A1 (en) | 2007-10-02 | 2007-10-02 | Increasing methionine yield |
| EPPCT/EP2007/060433 | 2007-10-02 | ||
| PCT/EP2008/062859 WO2009043803A2 (en) | 2007-10-02 | 2008-09-25 | Increasing methionine yield |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0818528A2 true BRPI0818528A2 (pt) | 2016-07-26 |
| BRPI0818528A8 BRPI0818528A8 (pt) | 2017-09-19 |
| BRPI0818528B1 BRPI0818528B1 (pt) | 2023-01-17 |
Family
ID=39521485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0818528-0A BRPI0818528B1 (pt) | 2007-10-02 | 2008-09-25 | Aumento do rendimento da metionina |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20100248311A1 (pt) |
| EP (2) | EP2205754B1 (pt) |
| JP (1) | JP5701604B2 (pt) |
| KR (2) | KR101586098B1 (pt) |
| CN (2) | CN103087971B (pt) |
| AR (1) | AR068722A1 (pt) |
| BR (1) | BRPI0818528B1 (pt) |
| DK (2) | DK2205754T3 (pt) |
| ES (2) | ES2557487T3 (pt) |
| HR (1) | HRP20160075T1 (pt) |
| HU (2) | HUE030032T2 (pt) |
| MX (1) | MX2010003609A (pt) |
| MY (2) | MY170749A (pt) |
| PL (2) | PL2573189T3 (pt) |
| RU (1) | RU2010115225A (pt) |
| WO (2) | WO2009043372A1 (pt) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4110641B2 (ja) | 1998-11-17 | 2008-07-02 | 味の素株式会社 | 発酵法によるl−メチオニンの製造法 |
| EP2121954A2 (en) * | 2007-02-19 | 2009-11-25 | Evonik Degussa GmbH | Coryneform bacteria with formate-thf-synthetase and/or glycine cleavage activity |
| WO2010020290A1 (en) | 2008-08-22 | 2010-02-25 | Metabolic Explorer | Producing methionine without n-acetyl methionine |
| WO2010020289A1 (en) | 2008-08-22 | 2010-02-25 | Metabolic Explorer | Production of n-acetylated sulphur-containing amino acids with microorganisms having enhanced n-acetyltransferase enzymatic activity |
| DE102009030342A1 (de) | 2009-06-25 | 2010-12-30 | Evonik Degussa Gmbh | Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen |
| FR2951195B1 (fr) | 2009-10-14 | 2014-01-31 | Roquette Freres | Composition riche en methionine destinee a l'alimentation animale |
| CN102666838B (zh) | 2009-11-18 | 2018-04-10 | 麦兰特公司 | 用于高效产生化学品的工程化微生物 |
| WO2011073738A1 (en) * | 2009-12-14 | 2011-06-23 | Metabolic Explorer | Use of inducible promoters in the production of methionine |
| KR101770123B1 (ko) | 2009-12-30 | 2017-08-23 | 에보니크 데구사 게엠베하 | 숙시네이트 데히드로게나제의 과다발현에 의한 메티오닌 생산의 증가 |
| CN102782137B (zh) | 2009-12-30 | 2016-01-06 | 代谢探索者公司 | 用于甲硫氨酸生产的菌株和方法 |
| AR083468A1 (es) * | 2010-10-25 | 2013-02-27 | Metabolic Explorer Sa | Aumento de la disponibilidad de nadph para la produccion de metionina |
| WO2012090021A1 (en) | 2010-12-30 | 2012-07-05 | Metabolic Explorer | Recombinant microorganism for the fermentative production of methionine |
| EP2658987B1 (en) | 2010-12-30 | 2014-12-10 | Metabolic Explorer | Fermentative production of methionine hydroxy analog (mha) |
| EP2479279A1 (de) | 2011-01-20 | 2012-07-25 | Evonik Degussa GmbH | Verfahren zur fermentativen Herstellung schwefelhaltiger Aminosäuren |
| WO2012137689A1 (ja) | 2011-04-01 | 2012-10-11 | 味の素株式会社 | L-システインの製造法 |
| US9234223B2 (en) | 2011-04-01 | 2016-01-12 | Ajinomoto Co., Inc. | Method for producing L-cysteine |
| DE102011006716A1 (de) | 2011-04-04 | 2012-10-04 | Evonik Degussa Gmbh | Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung |
| DE102011118019A1 (de) | 2011-06-28 | 2013-01-03 | Evonik Degussa Gmbh | Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens |
| AR086790A1 (es) * | 2011-06-29 | 2014-01-22 | Metabolic Explorer Sa | Un microorganismo para la produccion de metionina con importacion de glucosa mejorada |
| FR2983870B1 (fr) | 2011-12-08 | 2015-07-17 | Roquette Freres | Composition en methionine destinee a l'alimentation animale |
| EP2628792A1 (de) | 2012-02-17 | 2013-08-21 | Evonik Industries AG | Zelle mit verringerter ppGppase-Aktivität |
| US9347048B2 (en) | 2012-04-27 | 2016-05-24 | Evonik Technochemie Gmbh | Feedback-resistant alpha-isopropylmalate synthases |
| EP2861726B1 (en) | 2012-06-18 | 2017-05-31 | Evonik Degussa GmbH | Recombinant microorganism for the fermentative production of methionine |
| PL2700715T3 (pl) | 2012-08-20 | 2019-03-29 | Evonik Degussa Gmbh | Sposób fermentacyjnego wytwarzania L-aminokwasów z zastosowaniem ulepszonych szczepów z rodziny Enterobacteriaceae |
| WO2014049382A2 (en) | 2012-09-26 | 2014-04-03 | Metabolic Explorer | Ethylenediamine fermentative production by a recombinant microorganism |
| DE102012024435A1 (de) | 2012-12-14 | 2014-07-10 | Forschungszentrum Jülich GmbH | Verfahren zur Identifizierung einer Zelle mit gegenüber ihrem Wildtyp erhöhten intrazellulären Konzentration eines bestimmten Metaboliten, wobei die Veränderung der Zelle durch Rekombi-neering erreicht wird, sowie ein Verfahren zur Herstellung einer gegenüber ihrem Wildtyp genetisch veränderten Produktionszelle mit optimierter Produktion eines bestimmten Metaboliten, ein Verfahren zur Herstellung dieses Metaboliten, sowie dafür geeignete Nukleinsäuren |
| EP2762571A1 (de) | 2013-01-30 | 2014-08-06 | Evonik Industries AG | Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren |
| HUE032752T2 (en) | 2013-06-03 | 2017-10-30 | Evonik Degussa Gmbh | A method for the preparation of L-valine using recombinant corynebacteria containing propionate-inducible ilvBN operon |
| BR112016004367B1 (pt) | 2013-08-30 | 2022-06-14 | Evonik Operations Gmbh | Microrganismo recombinante e método para a produção fermentativa de metionina e/ou seus derivados |
| EP2940039A1 (de) * | 2014-04-30 | 2015-11-04 | Evonik Degussa GmbH | Verfahren zur Produktion von L-Aminosäuren in Corynebakterien unter Verwendung eines Glycin spaltenden Systems |
| CN103981206B (zh) * | 2014-06-06 | 2016-03-02 | 中国科学院天津工业生物技术研究所 | 一种筛选高产苏氨酸菌株的方法 |
| WO2016034536A1 (en) * | 2014-09-01 | 2016-03-10 | Metabolic Explorer | Method and microorganism for methionine production by fermentation with improved methionine efflux |
| CA2978228A1 (en) * | 2015-03-18 | 2016-09-22 | Basf Se | Recombinant microorganism for improved production of fine chemicals |
| ES2811337T3 (es) | 2015-04-07 | 2021-03-11 | Metabolic Explorer Sa | Microorganismo modificado para la producción optimizada de 2,4-dihidroxibutirato con eflujo de 2,4- dihidroxibutirato aumentado |
| CN108026516A (zh) * | 2015-08-07 | 2018-05-11 | 赢创德固赛有限公司 | 通过发酵的蛋白硫代羧化物依赖性l-甲硫氨酸生产 |
| FR3041658B1 (fr) | 2015-09-30 | 2017-10-20 | Arkema France | Procede de production de l-methionine |
| FR3041659B1 (fr) | 2015-09-30 | 2017-10-20 | Arkema France | Procede de production de l-methionine |
| MY186059A (en) | 2015-11-27 | 2021-06-17 | Evonik Operations Gmbh | Method for producing l-methionine |
| US9988624B2 (en) | 2015-12-07 | 2018-06-05 | Zymergen Inc. | Microbial strain improvement by a HTP genomic engineering platform |
| BR112018011503A2 (pt) | 2015-12-07 | 2018-12-04 | Zymergen Inc | promotores da corynebacterium glutamicum |
| US11208649B2 (en) | 2015-12-07 | 2021-12-28 | Zymergen Inc. | HTP genomic engineering platform |
| CN108603207A (zh) | 2016-01-08 | 2018-09-28 | 赢创德固赛有限公司 | 通过发酵生产来生产l-甲硫氨酸的方法 |
| WO2018005793A1 (en) | 2016-06-30 | 2018-01-04 | Zymergen Inc. | Methods for generating a glucose permease library and uses thereof |
| KR102345899B1 (ko) | 2016-06-30 | 2021-12-31 | 지머젠 인코포레이티드 | 박테리아 헤모글로빈 라이브러리를 생성하는 방법 및 이의 용도 |
| EP3296404A1 (en) | 2016-09-15 | 2018-03-21 | Evonik Degussa GmbH | Modified microorganism for production of methionine |
| US11560584B2 (en) | 2016-12-30 | 2023-01-24 | Quidel Corporation | Phage-mediated immunoassay and methods for determining susceptibility of bacteria to antibiotic or probiotic agents |
| EP3354742A1 (en) | 2017-01-26 | 2018-08-01 | Metabolic Explorer | Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid |
| US20200239897A1 (en) | 2017-06-07 | 2020-07-30 | Zymergen Inc. | Promoters from corynebacterium glutamicum and uses thereof in regulating ancillary gene expression |
| JP2020526205A (ja) | 2017-07-11 | 2020-08-31 | アディッソ・フランス・エス.エー.エス.Adisseo France S.A.S. | メチオニン生産酵母 |
| WO2019070612A1 (en) | 2017-10-02 | 2019-04-11 | Quidel Corporation | PHAGE-BASED DETECTION METHOD FOR ANTIMICROBIAL SUSCEPTIBILITY TESTING AND IDENTIFICATION OF BACTERIAL SPECIES |
| CN109055289B (zh) * | 2018-07-27 | 2020-10-27 | 浙江工业大学 | 一种高产l-甲硫氨酸的重组大肠杆菌及其应用 |
| CN109652351B (zh) * | 2018-12-18 | 2020-08-04 | 江南大学 | 一种高产5-甲基四氢叶酸重组枯草芽孢杆菌及其应用 |
| CN113388630B (zh) * | 2020-03-11 | 2022-07-26 | 华东理工大学 | 合成l-半胱氨酸的重组大肠杆菌的构建方法及其应用 |
| CN116249778A (zh) | 2020-07-15 | 2023-06-09 | 赢创运营有限公司 | 编码氨基酸序列、编码氧化还原酶的多核苷酸 |
| CN112779200B (zh) * | 2021-01-12 | 2022-07-08 | 浙江工业大学 | 高产l-甲硫氨酸的基因工程菌及其构建与应用 |
| EP4384537A1 (en) | 2021-08-09 | 2024-06-19 | Evonik Operations GmbH | Method for producing a recombinant bacterial collagen-like protein (clp) |
| EP4384539A1 (en) | 2021-08-09 | 2024-06-19 | Evonik Operations GmbH | Polynucleotide encoding a bacterial collagen-like protein |
| CN117813315A (zh) | 2021-08-09 | 2024-04-02 | 赢创运营有限公司 | 用于生产重组细菌胶原样蛋白(clp)的方法 |
| EP4404988B1 (en) | 2021-09-20 | 2025-10-29 | Evonik Operations GmbH | Non-adhesive collagen-like hydrogels |
| EP4482541A1 (en) | 2022-02-25 | 2025-01-01 | Evonik Operations GmbH | Sponges based on collagen-like proteins |
| WO2023165952A1 (en) | 2022-03-01 | 2023-09-07 | Evonik Operations Gmbh | Biotechnological production of collagen proteins and bacterial collagen-like proteins by recombinant microorganisms |
| CN121263216A (zh) | 2023-06-06 | 2026-01-02 | 赢创运营有限公司 | 由胶原样蛋白(clp)制备的水凝胶贴剂 |
| CN116590209A (zh) | 2023-06-13 | 2023-08-15 | 浙江工业大学 | 一种产d-泛酸的基因工程菌、构建方法及应用 |
| WO2025016819A1 (en) | 2023-07-20 | 2025-01-23 | Evonik Operations Gmbh | Sponge comprising a recombinant collagen-like peptide (clp) and bioactive glass |
| WO2025186007A1 (en) | 2024-03-08 | 2025-09-12 | Evonik Operations Gmbh | Collagen-like protein coated medical devices and coating method thereof |
| WO2025217267A1 (en) * | 2024-04-11 | 2025-10-16 | Natáur Inc. | Platform for bio-based production of high levels of o-phosphoserine, cysteate or taurine |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0796916A1 (en) * | 1996-03-22 | 1997-09-24 | Triple-A B.V. | Improvement of amino acid fermentation processes |
| JP3207746B2 (ja) | 1996-03-25 | 2001-09-10 | シャープ株式会社 | ファクシミリ装置 |
| GB9724627D0 (en) * | 1997-11-20 | 1998-01-21 | Genencor Int Bv | Gram positive microorganism formate pathway |
| JP2000157267A (ja) | 1998-11-24 | 2000-06-13 | Ajinomoto Co Inc | 変異型metJ遺伝子及びL−メチオニンの製造法 |
| WO2004076659A2 (fr) | 2003-02-18 | 2004-09-10 | Metabolic Explorer | Procede de preparation de microorganismes evolues permettant la creation ou la modification de voies metaboliques |
| KR100488463B1 (ko) | 2003-07-24 | 2005-05-11 | 엘지전자 주식회사 | 플라즈마 디스플레이 패널의 구동장치 및 방법 |
| WO2005111202A1 (en) | 2004-05-12 | 2005-11-24 | Metabolic Explorer | Recombinant enzyme with altered feedback sensitivity |
| KR100651220B1 (ko) | 2004-06-29 | 2006-11-29 | 씨제이 주식회사 | L-메씨오닌 생산 균주 및 상기 균주를 이용한l-메씨오닌의 생산방법 |
| KR100656590B1 (ko) * | 2004-07-30 | 2006-12-11 | 한국과학기술원 | 박테리아 변이균주 및 이를 이용한 숙신산 및 아미노산의제조방법 |
| JP2008529485A (ja) * | 2005-02-07 | 2008-08-07 | メタボリック エクスプローラー | 低いγ脱離活性を有する発現酵素を含む微生物 |
| KR20080036608A (ko) | 2005-07-18 | 2008-04-28 | 바스프 에스이 | 메티오닌 생산 재조합 미생물 |
| CA2620468A1 (en) * | 2005-08-18 | 2007-02-22 | Basf Aktiengesellschaft | Microorganisms with increased efficiency for methionine synthesis |
| CN101291590A (zh) | 2005-10-31 | 2008-10-22 | 巴斯夫欧洲公司 | 用于制备l-甲硫氨酸的微生物和方法 |
| US8389250B2 (en) * | 2006-01-04 | 2013-03-05 | Metabolic Explorer | Methods for producing methionine by culturing a microorganism modified to enhance production of cysteine |
| EP2121954A2 (en) * | 2007-02-19 | 2009-11-25 | Evonik Degussa GmbH | Coryneform bacteria with formate-thf-synthetase and/or glycine cleavage activity |
-
2007
- 2007-10-02 WO PCT/EP2007/060433 patent/WO2009043372A1/en not_active Ceased
-
2008
- 2008-09-25 PL PL12198802T patent/PL2573189T3/pl unknown
- 2008-09-25 MY MYPI2013002263A patent/MY170749A/en unknown
- 2008-09-25 US US12/681,177 patent/US20100248311A1/en not_active Abandoned
- 2008-09-25 WO PCT/EP2008/062859 patent/WO2009043803A2/en not_active Ceased
- 2008-09-25 CN CN201210557318.0A patent/CN103087971B/zh active Active
- 2008-09-25 CN CN2008801100599A patent/CN101821401B/zh active Active
- 2008-09-25 HU HUE12198802A patent/HUE030032T2/en unknown
- 2008-09-25 KR KR1020107009579A patent/KR101586098B1/ko active Active
- 2008-09-25 ES ES08804748.5T patent/ES2557487T3/es active Active
- 2008-09-25 DK DK08804748.5T patent/DK2205754T3/en active
- 2008-09-25 KR KR1020157006914A patent/KR101636662B1/ko active Active
- 2008-09-25 BR BRPI0818528-0A patent/BRPI0818528B1/pt active IP Right Grant
- 2008-09-25 JP JP2010527412A patent/JP5701604B2/ja not_active Expired - Fee Related
- 2008-09-25 ES ES12198802.6T patent/ES2600036T3/es active Active
- 2008-09-25 MY MYPI2010001302A patent/MY180720A/en unknown
- 2008-09-25 DK DK12198802.6T patent/DK2573189T3/en active
- 2008-09-25 HU HUE08804748A patent/HUE026672T2/en unknown
- 2008-09-25 MX MX2010003609A patent/MX2010003609A/es active IP Right Grant
- 2008-09-25 EP EP08804748.5A patent/EP2205754B1/en not_active Not-in-force
- 2008-09-25 RU RU2010115225/10A patent/RU2010115225A/ru not_active Application Discontinuation
- 2008-09-25 PL PL08804748T patent/PL2205754T3/pl unknown
- 2008-09-25 HR HRP20160075TT patent/HRP20160075T1/hr unknown
- 2008-09-25 EP EP12198802.6A patent/EP2573189B1/en not_active Not-in-force
- 2008-10-02 AR ARP080104317A patent/AR068722A1/es unknown
-
2016
- 2016-02-12 US US15/043,138 patent/US10858679B2/en active Active
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