BRPI0817806A2 - Análogos de quinolona e métodos relacionados a estes - Google Patents

Análogos de quinolona e métodos relacionados a estes

Info

Publication number: BRPI0817806A2
Authority: BR; Brazil
Prior art keywords: related methods; quinolone analogs; quinolone; analogs; methods
Prior art date: 2007-10-05

Application number

BRPI0817806-2A2A

Other languages

English (en)

Inventor

Johnny Yasuo Nagasawa

Fabrice Pierre

Mustapha Haddach

Michael Schwaebe

Levan Darjania

Jeffrey P Whitten

Original Assignee

Cylene Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-05

Filing date

2008-10-03

Publication date

2014-10-07

2008-10-03 Application filed by Cylene Pharmaceuticals Inc filed Critical Cylene Pharmaceuticals Inc

2014-10-07 Publication of BRPI0817806A2 publication Critical patent/BRPI0817806A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/16—Peri-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Epidemiology (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)

BRPI0817806-2A2A 2007-10-05 2008-10-03 Análogos de quinolona e métodos relacionados a estes BRPI0817806A2 (pt)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US97804207P	2007-10-05	2007-10-05
US3868108P	2008-03-21	2008-03-21
US4593308P	2008-04-17	2008-04-17
PCT/US2008/078859 WO2009046383A1 (en)	2007-10-05	2008-10-03	Quinolone analogs and methods related thereto

Publications (1)

Publication Number	Publication Date
BRPI0817806A2 true BRPI0817806A2 (pt)	2014-10-07

Family

ID=40523786

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0817806-2A2A BRPI0817806A2 (pt)	2007-10-05	2008-10-03	Análogos de quinolona e métodos relacionados a estes

Country Status (18)

Country	Link
US (2)	US7928100B2 (pt)
EP (2)	EP3092901B1 (pt)
JP (2)	JP5824213B2 (pt)
KR (2)	KR101682867B1 (pt)
CN (1)	CN101888780B (pt)
AU (1)	AU2008308485B2 (pt)
BR (1)	BRPI0817806A2 (pt)
CA (1)	CA2701630C (pt)
DK (1)	DK3092901T3 (pt)
ES (2)	ES2582662T3 (pt)
IL (2)	IL204844A (pt)
MX (1)	MX2010003685A (pt)
NO (1)	NO20100596L (pt)
NZ (1)	NZ584892A (pt)
PL (2)	PL3092901T3 (pt)
PT (2)	PT2214491T (pt)
RU (1)	RU2549895C2 (pt)
WO (1)	WO2009046383A1 (pt)

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PT2214491T (pt) *	2007-10-05	2016-10-25	Senhwa Biosciences Inc	Análogos de quinolona e métodos com eles relacionados
WO2011025889A1 (en)	2009-08-28	2011-03-03	Takeda Pharmaceutical Company Limited	HEXAHYDROOXAZINOPTERINE COMPOUNDS FOR USE AS mTOR INHIBITORS
US8293925B2 (en) *	2009-09-21	2012-10-23	Chemocentryx, Inc.	Pyrrolidinone carboxamide derivatives
ES2533042T3 (es)	2011-02-25	2015-04-07	Takeda Pharmaceutical Company Limited	Oxazinopteridinas y oxazinopteridinonas N-sustituidas
WO2012123938A1 (en)	2011-03-17	2012-09-20	Tel Hashomer Medical Research Infrastructure And Services Ltd.	Quinolone analogs for treating autoimmune diseases
GB201206384D0 (en) *	2012-04-11	2012-05-23	Redx Pharma Ltd	Antibacterial drug derivatives
CN104177379B (zh) *	2013-05-22	2016-12-28	中国科学院上海药物研究所	一种喹诺酮类化合物或其立体化学异构体、包含该化合物的药物组合物及其用途
EP3074391B1 (en)	2013-11-28	2019-07-31	Tel Hashomer Medical Research Infrastructure And Services Ltd.	Rna polymerase i inhibitors and uses thereof
PL3140305T3 (pl) *	2014-05-09	2018-10-31	Pimera, Inc.	Nowe kompozycje, ich zastosowania i sposoby wytwarzania
US9758518B2 (en)	2015-03-04	2017-09-12	Pimera, Inc.	Compositions, uses and methods for making them
EP3377068B1 (en)	2015-11-20	2025-03-26	Senhwa Biosciences, Inc.	Combination therapy of tetracyclic quinolone analogs for treating cancer
US9957282B2 (en)	2015-12-14	2018-05-01	Senhwa Biosciences, Inc.	Crystalline forms of quinolone analogs and their salts
RU2018124599A (ru) *	2015-12-14	2020-01-16	Сэньхва Байосайенсиз, Инк.	Кристаллические формы аналогов хинолона и их солей
TWI765848B (zh) *	2015-12-14	2022-06-01	生華生物科技股份有限公司	喹諾酮類似物及其鹽的結晶形式
CN109640959B (zh)	2016-04-29	2023-03-17	西奈山伊坎医学院	靶向先天免疫系统以诱导长期耐受性及解决动脉粥样硬化中的巨噬细胞累积
US11912706B2 (en)	2017-03-28	2024-02-27	Pimera, Inc.	Crystal forms of a POL1 inhibitor
US11071727B2 (en)	2018-01-26	2021-07-27	Northwestern University	Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors
RU2020130050A (ru) *	2018-02-15	2022-03-15	Сэньхва Байосайенсиз, Инк.	Аналоги хинолонов и их соли, композиции и способ их применения
WO2020051342A1 (en) *	2018-09-06	2020-03-12	Cornell University	Methods for treating metastatic disease using ribosome biogenesis inhibitor cx 5461
WO2021030671A1 (en) *	2019-08-14	2021-02-18	Senhwa Biosciences, Inc.	Tetracyclic compounds and their salts, compositions, and methods for their use
BR112022002772A2 (pt) *	2019-08-14	2022-08-09	Senhwa Biosciences Inc	Formas cristalinas de análogos de quinolina e sais dos mesmos, composições e seus métodos para uso
JP2020189888A (ja) *	2020-08-28	2020-11-26	センワバイオサイエンシズインコーポレイテッド	キノロン類似体及びその塩の結晶形
US12274700B1 (en)	2020-10-30	2025-04-15	Accencio LLC	Methods of treating symptoms of coronavirus infection with RNA polymerase inhibitors
CN114573604B (zh) *	2020-12-01	2024-06-18	中国科学院上海药物研究所	一类基于喹诺酮的化合物、其制备方法、包含其的药物组合物及其用途
KR20230171435A (ko)	2021-03-19	2023-12-20	트레인드 테라퓨틱스 디스커버리, 아이엔씨.	훈련된 면역을 조절하기 위한 화합물 및 이의 사용 방법
CN114409681A (zh) *	2022-03-18	2022-04-29	信义核新(北京)生物科技有限公司	用于治疗dna损伤修复缺陷肿瘤的喹诺酮类似物及其应用
WO2024222147A1 (zh) *	2023-04-23	2024-10-31	信义核新(北京)生物科技有限公司	喹诺酮类似物及其用途
CN121399139A (zh) *	2023-04-23	2026-01-23	信义核新(北京)生物科技有限公司	喹诺酮衍生物及其在抗肿瘤中的应用
WO2025114459A1 (en) *	2023-11-28	2025-06-05	Genome Therapeutics Ltd	Tetracyclic compounds for use in antibody-drug conjugates for the treatment of cancer
WO2025133338A1 (en) *	2023-12-21	2025-06-26	Genome Therapeutics Ltd	Quinolone derivatves against cancer

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LU84979A1 (fr)	1983-08-30	1985-04-24	Oreal	Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
US4820508A (en)	1987-06-23	1989-04-11	Neutrogena Corporation	Skin protective composition
US4992478A (en)	1988-04-04	1991-02-12	Warner-Lambert Company	Antiinflammatory skin moisturizing composition and method of preparing same
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US20100305136A1 (en) *	2006-06-08	2010-12-02	Johnny Yasuo Nagasawa	Quinolone analogs derivatized with sulfonic acid, sulfonate or sulfonamide
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PT2214491T (pt)	2007-10-05	2016-10-25	Senhwa Biosciences Inc	Análogos de quinolona e métodos com eles relacionados

2008
- 2008-10-03 PT PT88353420T patent/PT2214491T/pt unknown
- 2008-10-03 NZ NZ584892A patent/NZ584892A/en unknown
- 2008-10-03 PL PL16171555T patent/PL3092901T3/pl unknown
- 2008-10-03 RU RU2010117225/04A patent/RU2549895C2/ru not_active Application Discontinuation
- 2008-10-03 WO PCT/US2008/078859 patent/WO2009046383A1/en not_active Ceased
- 2008-10-03 PT PT161715552T patent/PT3092901T/pt unknown
- 2008-10-03 JP JP2010528194A patent/JP5824213B2/ja active Active
- 2008-10-03 AU AU2008308485A patent/AU2008308485B2/en active Active
- 2008-10-03 KR KR1020167002742A patent/KR101682867B1/ko active Active
- 2008-10-03 EP EP16171555.2A patent/EP3092901B1/en active Active
- 2008-10-03 MX MX2010003685A patent/MX2010003685A/es not_active Application Discontinuation
- 2008-10-03 EP EP08835342.0A patent/EP2214491B1/en active Active
- 2008-10-03 ES ES08835342.0T patent/ES2582662T3/es active Active
- 2008-10-03 BR BRPI0817806-2A2A patent/BRPI0817806A2/pt not_active IP Right Cessation
- 2008-10-03 ES ES16171555T patent/ES2791305T3/es active Active
- 2008-10-03 US US12/245,619 patent/US7928100B2/en active Active
- 2008-10-03 DK DK16171555.2T patent/DK3092901T3/da active
- 2008-10-03 CA CA2701630A patent/CA2701630C/en active Active
- 2008-10-03 KR KR1020107009924A patent/KR101601332B1/ko active Active
- 2008-10-03 PL PL08835342.0T patent/PL2214491T3/pl unknown
- 2008-10-03 CN CN200880119635.6A patent/CN101888780B/zh active Active
2010
- 2010-04-06 IL IL204844A patent/IL204844A/en active IP Right Grant
- 2010-04-26 NO NO20100596A patent/NO20100596L/no not_active Application Discontinuation
2011
- 2011-03-09 US US13/043,956 patent/US8853234B2/en active Active
2014
- 2014-05-14 JP JP2014100136A patent/JP2014159474A/ja not_active Withdrawn
2017
- 2017-01-02 IL IL249906A patent/IL249906B/en active IP Right Grant

Also Published As

Publication number	Publication date
PL3092901T3 (pl)	2020-10-19
DK3092901T3 (da)	2020-05-18
IL204844A0 (en)	2010-11-30
WO2009046383A1 (en)	2009-04-09
KR20160020578A (ko)	2016-02-23
EP2214491B1 (en)	2016-07-13
CA2701630A1 (en)	2009-04-09
KR101682867B1 (ko)	2016-12-05
EP2214491A4 (en)	2010-11-10
AU2008308485B2 (en)	2014-08-07
US7928100B2 (en)	2011-04-19
NZ584892A (en)	2012-06-29
EP3092901A1 (en)	2016-11-16
CN101888780B (zh)	2014-08-13
EP3092901B1 (en)	2020-04-29
EP2214491A1 (en)	2010-08-11
PT3092901T (pt)	2020-05-21
CN101888780A (zh)	2010-11-17
KR20100064392A (ko)	2010-06-14
JP2010540663A (ja)	2010-12-24
ES2791305T3 (es)	2020-11-03
RU2010117225A (ru)	2011-11-10
AU2008308485A1 (en)	2009-04-09
MX2010003685A (es)	2010-06-02
PL2214491T3 (pl)	2016-11-30
HK1150728A1 (en)	2012-01-13
US20090093455A1 (en)	2009-04-09
JP2014159474A (ja)	2014-09-04
IL249906A0 (en)	2017-03-30
PT2214491T (pt)	2016-10-25
JP5824213B2 (ja)	2015-11-25
ES2582662T3 (es)	2016-09-14
IL204844A (en)	2017-01-31
US8853234B2 (en)	2014-10-07
NO20100596L (no)	2010-06-10
KR101601332B1 (ko)	2016-03-08
IL249906B (en)	2020-10-29
CA2701630C (en)	2016-10-25
US20110218184A1 (en)	2011-09-08
RU2549895C2 (ru)	2015-05-10

Publication	Publication Date	Title
BRPI0817806A2 (pt)	2014-10-07	Análogos de quinolona e métodos relacionados a estes
BRPI0918097A2 (pt)	2015-12-08	dispositivo respiratório de interface
IT1393131B1 (it)	2012-04-11	Controvento a ingobbamento limitato
BRPI0918105A2 (pt)	2015-11-24	dispositivo de interface respiratória
BRPI0917623A2 (pt)	2015-11-17	dispositivo de interface respiratória
BRPI0913569A2 (pt)	2016-10-04	anotação de imagens
BRPI0907457A2 (pt)	2015-07-14	Absorventes
FI20080417A0 (fi)	2008-06-27	Hammashoitolaitteisto
EP2351549A4 (en)	2015-06-24	INTERCONNECTS
DK2235384T3 (da)	2014-07-07	Forbindelsesindretning
BRPI0813647A2 (pt)	2014-12-23	Piperazinil oxoalquil tetrahidro-beta-carbolinas e análogos relacionados
BRPI0818345A2 (pt)	2015-04-07	Dispositivo de inalação
EP2303378A4 (en)	2016-06-15	INTERFACE
EP2277301A4 (en)	2013-01-02	IMPROVED HEADSET
BRPI0812350A2 (pt)	2015-02-10	Conexão
DK2837348T3 (da)	2020-05-04	Kryokirurgiske fremgangsmåder
BRPI0814876A2 (pt)	2014-09-30	Análogos de pirona fosforilados e métodos
DK2155273T3 (da)	2013-04-22	Lugtregulerende genstand
NO20070333L (no)	2008-07-21	En friksjonsokende innretning
BRPI0916695A2 (pt)	2015-11-17	tampão
BRPI0818773A2 (pt)	2015-04-14	Moduladores de gama-secretase ligados a carbono
FI20061029L (fi)	2008-05-22	Hammashoitolaitteisto
EP2294157A4 (en)	2015-08-26	Heat generating nanomaterials
FI20061024A0 (fi)	2006-11-21	Hammashoitolaitteisto
IT1397375B1 (it)	2013-01-10	Cassero a disarmo rapido

Legal Events

Date	Code	Title	Description
2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.
2016-03-29	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.