BRPI0814876A2 - Análogos de pirona fosforilados e métodos - Google Patents
Análogos de pirona fosforilados e métodosInfo
- Publication number
- BRPI0814876A2 BRPI0814876A2 BRPI0814876-7A2A BRPI0814876A BRPI0814876A2 BR PI0814876 A2 BRPI0814876 A2 BR PI0814876A2 BR PI0814876 A BRPI0814876 A BR PI0814876A BR PI0814876 A2 BRPI0814876 A2 BR PI0814876A2
- Authority
- BR
- Brazil
- Prior art keywords
- pyrona
- phosphorilated
- analogs
- methods
- pyrona analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/6574—Esters of oxyacids of phosphorus
- C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95318807P | 2007-07-31 | 2007-07-31 | |
| US7660808P | 2008-06-27 | 2008-06-27 | |
| PCT/US2008/071588 WO2009018338A2 (en) | 2007-07-31 | 2008-07-30 | Phosphorylated pyrone analogs and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0814876A2 true BRPI0814876A2 (pt) | 2014-09-30 |
Family
ID=40305253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0814876-7A2A BRPI0814876A2 (pt) | 2007-07-31 | 2008-07-30 | Análogos de pirona fosforilados e métodos |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US7947733B2 (pt) |
| EP (1) | EP2182957A4 (pt) |
| JP (1) | JP2011500512A (pt) |
| KR (1) | KR20100051829A (pt) |
| CN (1) | CN101969959A (pt) |
| AU (1) | AU2008282261A1 (pt) |
| BR (1) | BRPI0814876A2 (pt) |
| CA (1) | CA2693338A1 (pt) |
| GB (1) | GB2464645B (pt) |
| MX (1) | MX2010001141A (pt) |
| TW (1) | TW200924785A (pt) |
| WO (1) | WO2009018338A2 (pt) |
| ZA (1) | ZA201001390B (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2693340A1 (en) * | 2007-07-31 | 2009-02-05 | Limerick Biopharma, Inc. | Pyrone analog compositions and methods |
| GB2464645B (en) | 2007-07-31 | 2010-11-24 | Limerick Biopharma Inc | Quercetin-3'-O-phosphate and its uses |
| EP2355814A2 (en) * | 2008-10-10 | 2011-08-17 | Limerick BioPharma, Inc. | Pyrones for the treatment of metabolic disorders |
| EP2424541A2 (en) * | 2009-04-27 | 2012-03-07 | Limerick BioPharma, Inc. | Phosphorylated and phosphonated pyrone analogs for therapeutic treatment |
| AU2011242689B2 (en) | 2010-04-23 | 2015-09-17 | Kineta, Inc. | Anti-viral compounds |
| WO2012068539A1 (en) * | 2010-11-19 | 2012-05-24 | Limerick Biopharma, Inc. | Use and composition of quercetin-3'-o-sulfate for therapeutic treatment |
| US9458492B2 (en) | 2011-02-25 | 2016-10-04 | Kineta, Inc. | Methods and cells for identifying RIG-I pathway regulators |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| CN104530127B (zh) * | 2014-12-12 | 2016-09-14 | 广东东阳光药业有限公司 | 一种淫羊藿苷衍生物及其使用方法和用途 |
| CN106632479B (zh) * | 2016-12-22 | 2018-10-23 | 贵州大学 | O,o’-二烷基-o”-(取代黄酮-3-基)磷酸酯类衍生物、制备方法及应用 |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| US10881634B2 (en) * | 2017-12-07 | 2021-01-05 | Hughes Biotechnology Co., Ltd | Method for treatment or prevention of a disease associated with a decrease in bone mass and method of improving bone architecture and bio mechanical strength of bone |
| WO2020212952A1 (en) | 2019-04-17 | 2020-10-22 | Compass Pathfinder Limited | Treatment of depression and other various disorders with psilocybin |
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|---|---|---|---|---|
| FR837588A (fr) | 1938-03-25 | 1939-02-14 | Perfectionnements aux chaînes ou garnitures anti-patinantes et anti-dérapantes pour roues de véhicules | |
| US2764596A (en) | 1952-07-01 | 1956-09-25 | Nat Drug Co | Inorganic acid esters of polyhydroxylated flavones and flavanones |
| US4530844A (en) | 1984-07-26 | 1985-07-23 | Warner-Lambert Company | Synergistic non-steroidal anti-inflammatory compounds and compositions thereof |
| JPH01153695A (ja) * | 1987-12-11 | 1989-06-15 | Showa Denko Kk | ルチンまたはケルセチンリン酸エステルの製造法 |
| JPH01308476A (ja) | 1988-06-06 | 1989-12-13 | Showa Denko Kk | 紫外線吸収剤 |
| US6007840A (en) | 1988-09-16 | 1999-12-28 | Novartis Ag | Pharmaceutical compositions comprising cyclosporins |
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| GB2222770B (en) | 1988-09-16 | 1992-07-29 | Sandoz Ltd | Pharmaceutical compositions containing cyclosporins |
| US5643901A (en) | 1990-06-11 | 1997-07-01 | Fujisawa Pharmaceutical Co., Ltd. | Medicament for treating idiopathic thrombocytopenic purpura |
| US5348966A (en) | 1990-10-24 | 1994-09-20 | Fujisawa Pharmaceutical Co., Ltd. | Method for treating pyoderma and Sezary's syndrome using FK 506 and related compounds |
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| US20040102386A1 (en) | 2001-09-06 | 2004-05-27 | Thomas Lahey | Inhibition by 3-deoxyflavonoids of T-lymphocyte activation and therapies related thereto |
| US6774142B2 (en) | 2001-09-06 | 2004-08-10 | Thomas P. Lahey | Inhibition by 3-deoxyflavonoids of T-lymphocyte activation and therapies related thereto |
| GB0125532D0 (en) | 2001-10-24 | 2001-12-12 | Burton Michael | Enzyme activity indicators |
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| US7169763B2 (en) | 2002-02-22 | 2007-01-30 | Oliver Yoa-Pu Hu | Cytochrome P450 3A inhibitors and enhancers |
| GB2391471B (en) | 2002-08-02 | 2005-05-04 | Satishchandra Punambhai Patel | Pharmaceutical compositions |
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| US20050008640A1 (en) | 2003-04-23 | 2005-01-13 | Wendy Waegell | Method of treating transplant rejection |
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| CA2541590A1 (en) | 2003-10-10 | 2005-04-21 | Resverlogix Corp. | Treatment of diseases associated with the egr-1 enhancer element |
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| WO2005075449A1 (en) | 2004-02-03 | 2005-08-18 | Yale University | Compounds and methods to increase anti-p-glycoprotein activity of baicalein by alkylation on the a ring |
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| US20070087977A1 (en) | 2004-11-16 | 2007-04-19 | Wendye Robbins | Methods and compositions for treating pain |
| CA2601028C (en) | 2005-03-11 | 2014-05-27 | Howard Florey Institute Of Experimental Physiology And Medecine | Flavonoid compounds and uses thereof |
| US20080242599A1 (en) | 2005-05-03 | 2008-10-02 | Majd Zayzafoon | Compositions and Methods for Increasing Osteoblast Cell Differentiation and Bone Generation |
| CN101365446B (zh) * | 2005-07-29 | 2013-05-22 | 雷斯弗洛吉克斯公司 | 预防和治疗复杂疾病的药物组合物及其经由可植入医药装置的递送 |
| WO2007084857A2 (en) | 2006-01-13 | 2007-07-26 | President And Fellows Of Harvard College | Methods and compositions for treating cell proliferative disorders |
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| US20080161248A1 (en) | 2006-12-28 | 2008-07-03 | Wendye Robbins | Methods and Compositions for Therapeutic Treatment |
| CA2693340A1 (en) | 2007-07-31 | 2009-02-05 | Limerick Biopharma, Inc. | Pyrone analog compositions and methods |
| GB2464645B (en) | 2007-07-31 | 2010-11-24 | Limerick Biopharma Inc | Quercetin-3'-O-phosphate and its uses |
| WO2009018326A2 (en) | 2007-07-31 | 2009-02-05 | Limerick Biopharma, Inc. | Soluble pyrone analogs methods and compositions |
| WO2009158007A2 (en) * | 2008-06-27 | 2009-12-30 | Limerick Biopharma, Inc. | Methods and compositions for therapeutic treatment |
| WO2009158031A2 (en) | 2008-06-27 | 2009-12-30 | Limerick Biopharma, Inc. | Methods and compositions for therapeutic treatment |
| US20100297020A1 (en) | 2008-10-10 | 2010-11-25 | Limerick Biopharma, Inc. | Phosphorylated and phosphonated pyrone analogs for therapeutic treatment |
| EP2355814A2 (en) | 2008-10-10 | 2011-08-17 | Limerick BioPharma, Inc. | Pyrones for the treatment of metabolic disorders |
| EP2424541A2 (en) | 2009-04-27 | 2012-03-07 | Limerick BioPharma, Inc. | Phosphorylated and phosphonated pyrone analogs for therapeutic treatment |
-
2008
- 2008-07-30 GB GB1002044A patent/GB2464645B/en not_active Expired - Fee Related
- 2008-07-30 EP EP08782531A patent/EP2182957A4/en not_active Withdrawn
- 2008-07-30 CA CA2693338A patent/CA2693338A1/en not_active Abandoned
- 2008-07-30 US US12/182,992 patent/US7947733B2/en not_active Expired - Fee Related
- 2008-07-30 JP JP2010520153A patent/JP2011500512A/ja not_active Ceased
- 2008-07-30 CN CN2008801055593A patent/CN101969959A/zh active Pending
- 2008-07-30 KR KR1020107004292A patent/KR20100051829A/ko not_active Withdrawn
- 2008-07-30 AU AU2008282261A patent/AU2008282261A1/en not_active Abandoned
- 2008-07-30 MX MX2010001141A patent/MX2010001141A/es not_active Application Discontinuation
- 2008-07-30 WO PCT/US2008/071588 patent/WO2009018338A2/en not_active Ceased
- 2008-07-30 BR BRPI0814876-7A2A patent/BRPI0814876A2/pt not_active Application Discontinuation
- 2008-07-30 TW TW097128884A patent/TW200924785A/zh unknown
-
2010
- 2010-02-18 US US12/708,040 patent/US20100144612A1/en not_active Abandoned
- 2010-02-25 ZA ZA2010/01390A patent/ZA201001390B/en unknown
- 2010-04-22 US US12/765,580 patent/US20100204089A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20100144612A1 (en) | 2010-06-10 |
| CA2693338A1 (en) | 2009-02-05 |
| MX2010001141A (es) | 2010-03-01 |
| EP2182957A4 (en) | 2012-07-18 |
| US7947733B2 (en) | 2011-05-24 |
| AU2008282261A1 (en) | 2009-02-05 |
| JP2011500512A (ja) | 2011-01-06 |
| KR20100051829A (ko) | 2010-05-18 |
| US20090069273A1 (en) | 2009-03-12 |
| WO2009018338A2 (en) | 2009-02-05 |
| US20100204089A1 (en) | 2010-08-12 |
| WO2009018338A3 (en) | 2010-11-11 |
| EP2182957A2 (en) | 2010-05-12 |
| ZA201001390B (en) | 2011-05-25 |
| CN101969959A (zh) | 2011-02-09 |
| GB2464645B (en) | 2010-11-24 |
| TW200924785A (en) | 2009-06-16 |
| GB2464645A (en) | 2010-04-28 |
| GB201002044D0 (en) | 2010-03-24 |
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