BRPI0817417A2 - Análogos de aligonugleotídeo estimuladores imunes contendo frações de açúcar modificado - Google Patents

Análogos de aligonugleotídeo estimuladores imunes contendo frações de açúcar modificado

Info

Publication number: BRPI0817417A2
Authority: BR; Brazil
Prior art keywords: aligonugleotide; analogues; modified sugar; containing modified; immune stimulators
Prior art date: 2007-10-09

Application number

BRPI0817417-2A

Other languages

English (en)

Inventor

Harald Debelak

Marion Jurk

Eugen Uhlmann

Markus Weber

Original Assignee

Coley Pharm Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-09

Filing date

2008-09-29

Publication date

2015-06-16

2008-09-29 Application filed by Coley Pharm Gmbh filed Critical Coley Pharm Gmbh

2015-06-16 Publication of BRPI0817417A2 publication Critical patent/BRPI0817417A2/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/17—Immunomodulatory nucleic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/322—2'-R Modification

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
General Engineering & Computer Science (AREA)
Zoology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Wood Science & Technology (AREA)
Oncology (AREA)
Hematology (AREA)
Dermatology (AREA)
Communicable Diseases (AREA)
Biochemistry (AREA)
Mycology (AREA)
Plant Pathology (AREA)
Epidemiology (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Rheumatology (AREA)
Obesity (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)

BRPI0817417-2A 2007-10-09 2008-09-29 Análogos de aligonugleotídeo estimuladores imunes contendo frações de açúcar modificado BRPI0817417A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US99821507P	2007-10-09	2007-10-09
PCT/IB2008/002623 WO2009047610A1 (en)	2007-10-09	2008-09-29	Immune stimulatory oligonucleotide analogs containing modified sugar moieties

Publications (1)

Publication Number	Publication Date
BRPI0817417A2 true BRPI0817417A2 (pt)	2015-06-16

Family

ID=40404779

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0817417-2A BRPI0817417A2 (pt)	2007-10-09	2008-09-29	Análogos de aligonugleotídeo estimuladores imunes contendo frações de açúcar modificado

Country Status (12)

Country	Link
US (1)	US9186399B2 (pt)
EP (1)	EP2197488B1 (pt)
JP (1)	JP5738593B2 (pt)
KR (1)	KR20100068422A (pt)
CN (1)	CN101820908A (pt)
AU (1)	AU2008309264B2 (pt)
BR (1)	BRPI0817417A2 (pt)
CA (1)	CA2700812C (pt)
ES (1)	ES2486298T3 (pt)
MX (1)	MX2010003877A (pt)
RU (1)	RU2010112771A (pt)
WO (1)	WO2009047610A1 (pt)

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KR20100068422A (ko) *	2007-10-09	2010-06-23	콜리 파마슈티칼 게엠베하	변경된 당 잔기를 함유하는 면역자극성 올리고뉴클레오티드 유사체
GB201021867D0 (en)	2010-12-23	2011-02-02	Mologen Ag	Non-coding immunomodulatory DNA construct
LU92821B1 (en)	2015-09-09	2017-03-20	Mologen Ag	Combination comprising immunostimulatory oligonucleotides
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JP6869324B2 (ja)	2016-03-31	2021-05-12	チャンスーヤホンメディテックカンパニーリミテッド	ニトロキソリンおよびその類似体と、化学療法剤および免疫療法剤との、がんの治療における、組合せの使用
WO2021108202A1 (en) *	2019-11-25	2021-06-03	The Regents Of The University Of California	Modified viral therapeutics and uses thereof

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2008
- 2008-09-09 KR KR1020107007640A patent/KR20100068422A/ko not_active Ceased
- 2008-09-09 RU RU2010112771/10A patent/RU2010112771A/ru not_active Application Discontinuation
- 2008-09-09 CN CN200880111045.9A patent/CN101820908A/zh active Pending
- 2008-09-29 CA CA2700812A patent/CA2700812C/en not_active Expired - Fee Related
- 2008-09-29 EP EP08837065.5A patent/EP2197488B1/en not_active Not-in-force
- 2008-09-29 ES ES08837065.5T patent/ES2486298T3/es active Active
- 2008-09-29 BR BRPI0817417-2A patent/BRPI0817417A2/pt not_active IP Right Cessation
- 2008-09-29 MX MX2010003877A patent/MX2010003877A/es not_active Application Discontinuation
- 2008-09-29 WO PCT/IB2008/002623 patent/WO2009047610A1/en not_active Ceased
- 2008-09-29 JP JP2010528498A patent/JP5738593B2/ja not_active Expired - Fee Related
- 2008-09-29 AU AU2008309264A patent/AU2008309264B2/en not_active Ceased
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Publication number	Publication date
US20110098456A1 (en)	2011-04-28
AU2008309264A1 (en)	2009-04-16
EP2197488B1 (en)	2014-05-07
ES2486298T3 (es)	2014-08-18
US9186399B2 (en)	2015-11-17
AU2008309264A8 (en)	2011-07-07
JP5738593B2 (ja)	2015-06-24
AU2008309264B2 (en)	2013-02-14
JP2011500014A (ja)	2011-01-06
KR20100068422A (ko)	2010-06-23
CA2700812C (en)	2014-05-06
WO2009047610A1 (en)	2009-04-16
CN101820908A (zh)	2010-09-01
WO2009047610A8 (en)	2010-09-30
EP2197488A1 (en)	2010-06-23
MX2010003877A (es)	2010-04-30
RU2010112771A (ru)	2011-11-20
CA2700812A1 (en)	2009-04-16

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