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BRPI9902068B8 - nanodispersão, seu uso e sua pré-fase, e formulação farmacêutica líquida, semi-sólida ou sólida. - Google Patents

nanodispersão, seu uso e sua pré-fase, e formulação farmacêutica líquida, semi-sólida ou sólida.

Info

Publication number
BRPI9902068B8
BRPI9902068B8 BRPI9902068A BR9902068A BRPI9902068B8 BR PI9902068 B8 BRPI9902068 B8 BR PI9902068B8 BR PI9902068 A BRPI9902068 A BR PI9902068A BR 9902068 A BR9902068 A BR 9902068A BR PI9902068 B8 BRPI9902068 B8 BR PI9902068B8
Authority
BR
Brazil
Prior art keywords
nanodispersion
solid
liquid
semi
phase
Prior art date
Application number
BRPI9902068A
Other languages
English (en)
Other versions
BR9902068B1 (pt
BR9902068A (pt
Inventor
Werner Supersaxo Andreas
Hueglin Dietmar
Georg Weder Hans
Friedrich Roeding Joachim
Original Assignee
Ciba Speciality Chemicals Holding Inc
Vesifact Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Speciality Chemicals Holding Inc, Vesifact Ag filed Critical Ciba Speciality Chemicals Holding Inc
Publication of BR9902068A publication Critical patent/BR9902068A/pt
Publication of BR9902068B1 publication Critical patent/BR9902068B1/pt
Publication of BRPI9902068B8 publication Critical patent/BRPI9902068B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

patente de invenção: <b>"uso de nanodispersões em formulações farmacêuticas acabadas''<d>. é dada uma descrição do uso de uma nanodispersão que compreende: (a) uma molécula de formação de membrana, (b) um coemulsificante e (d) um componente lipofílico, em formulações farmacêuticas acabadas, a nanodispersão podendo ser obtida através de (<244>) misturação dos componentes (a), (b), (c) até que um líquido claro homogêneo seja obtido, e (<225>) adição do líquido obtido na etapa (<244>) à fase aquosa das formulações farmaceûticas acabadas, as etapas (<244>) e (<225>) sendo realizadas sem qualquer fornecimento adicional de energia. as nanodispersões usadas de acordo com a presente invenção são adequadas como veículos de transporte para agente farmacêuticos ativos.
BRPI9902068A 1998-05-11 1999-05-10 nanodispersão, seu uso e sua pré-fase, e formulação farmacêutica líquida, semi-sólida ou sólida. BRPI9902068B8 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98810422 1998-05-11

Publications (3)

Publication Number Publication Date
BR9902068A BR9902068A (pt) 2000-06-06
BR9902068B1 BR9902068B1 (pt) 2014-10-29
BRPI9902068B8 true BRPI9902068B8 (pt) 2021-05-25

Family

ID=8236078

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9902068A BRPI9902068B8 (pt) 1998-05-11 1999-05-10 nanodispersão, seu uso e sua pré-fase, e formulação farmacêutica líquida, semi-sólida ou sólida.

Country Status (20)

Country Link
US (2) US7081253B2 (pt)
EP (1) EP0956853B1 (pt)
JP (1) JP4755742B2 (pt)
KR (1) KR100622285B1 (pt)
CN (1) CN1220483C (pt)
AR (1) AR019274A1 (pt)
AT (1) ATE312597T1 (pt)
AU (1) AU767896B2 (pt)
BR (1) BRPI9902068B8 (pt)
CZ (1) CZ166999A3 (pt)
DE (1) DE59912910D1 (pt)
ES (1) ES2253871T3 (pt)
HU (1) HUP9901570A2 (pt)
ID (1) ID22565A (pt)
MY (1) MY133019A (pt)
PL (1) PL332934A1 (pt)
RU (1) RU2224505C2 (pt)
SG (1) SG71923A1 (pt)
TW (1) TWI241915B (pt)
ZA (1) ZA993200B (pt)

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Also Published As

Publication number Publication date
AU2805099A (en) 1999-11-18
US7871642B2 (en) 2011-01-18
JP4755742B2 (ja) 2011-08-24
ZA993200B (en) 1999-11-11
HUP9901570A2 (hu) 2001-06-28
CN1220483C (zh) 2005-09-28
US20060292191A1 (en) 2006-12-28
JPH11335266A (ja) 1999-12-07
PL332934A1 (en) 1999-11-22
KR100622285B1 (ko) 2006-09-11
ES2253871T3 (es) 2006-06-01
BR9902068B1 (pt) 2014-10-29
RU2224505C2 (ru) 2004-02-27
EP0956853B1 (de) 2005-12-14
EP0956853A2 (de) 1999-11-17
US7081253B2 (en) 2006-07-25
DE59912910D1 (de) 2006-01-19
AU767896B2 (en) 2003-11-27
ID22565A (id) 1999-11-11
EP0956853A3 (de) 2000-01-05
SG71923A1 (en) 2000-04-18
KR19990088156A (ko) 1999-12-27
CN1235017A (zh) 1999-11-17
CZ166999A3 (cs) 1999-11-17
HU9901570D0 (en) 1999-07-28
US20030190347A1 (en) 2003-10-09
ATE312597T1 (de) 2005-12-15
AR019274A1 (es) 2002-02-13
TWI241915B (en) 2005-10-21
MY133019A (en) 2007-10-31
BR9902068A (pt) 2000-06-06

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