BR9506305A - Aparelho e processo para preparação de formas sólidas com desprendimento controlado do ingrediente ativo - Google Patents

Aparelho e processo para preparação de formas sólidas com desprendimento controlado do ingrediente ativo

Info

Publication number: BR9506305A
Authority: BR; Brazil
Prior art keywords: solid forms; active ingredient; controlled release; preparing solid; pct
Prior art date: 1994-08-03

Application number

BR9506305A

Other languages

English (en)

Inventor

Lorenzo Rodriguez

Maurizio Cini

Cristina Cavallari

Giuseppe Motta

Original Assignee

Saitec Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-03

Filing date

1995-04-06

Publication date

1997-08-05

1995-04-06 Application filed by Saitec Srl filed Critical Saitec Srl

1997-08-05 Publication of BR9506305A publication Critical patent/BR9506305A/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
- B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/18—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Preparation (AREA)
Glanulating (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Moulds For Moulding Plastics Or The Like (AREA)
Molds, Cores, And Manufacturing Methods Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nozzles (AREA)

BR9506305A 1994-08-03 1995-04-06 Aparelho e processo para preparação de formas sólidas com desprendimento controlado do ingrediente ativo BR9506305A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ITBO940379A IT1274879B (it)	1994-08-03	1994-08-03	Apparecchio e metodo per preparare forme farmaceutiche solide a rilascio controllato del principio attivo.
PCT/IT1995/000048 WO1996003979A1 (en)	1994-08-03	1995-04-06	Apparatus and method for preparing solid forms with controlled release of the active ingredient

Publications (1)

Publication Number	Publication Date
BR9506305A true BR9506305A (pt)	1997-08-05

Family

ID=11339983

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9506305A BR9506305A (pt)	1994-08-03	1995-04-06	Aparelho e processo para preparação de formas sólidas com desprendimento controlado do ingrediente ativo

Country Status (19)

Country	Link
US (1)	US5707636A (pt)
EP (1)	EP0726765B1 (pt)
JP (1)	JPH09503441A (pt)
KR (1)	KR100348935B1 (pt)
CN (1)	CN1213735C (pt)
AT (1)	ATE202279T1 (pt)
AU (1)	AU693539B2 (pt)
BR (1)	BR9506305A (pt)
CA (1)	CA2173221A1 (pt)
DE (1)	DE69521406T2 (pt)
DK (1)	DK0726765T3 (pt)
ES (1)	ES2159632T3 (pt)
GR (1)	GR3036548T3 (pt)
IT (1)	IT1274879B (pt)
MX (1)	MX9601279A (pt)
PT (1)	PT726765E (pt)
RU (1)	RU2142792C1 (pt)
TW (1)	TW343149B (pt)
WO (1)	WO1996003979A1 (pt)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9819272D0 (en) *	1998-09-03	1998-10-28	Andaris Ltd	Microparticles
US6602521B1 (en) *	1998-09-29	2003-08-05	Impax Pharmaceuticals, Inc.	Multiplex drug delivery system suitable for oral administration
DE10009996B4 (de) *	2000-03-02	2005-10-13	Cognis Ip Management Gmbh	Feststoffgranulate mit monodisperser Korngrößenverteilung, ein Verfahren zu ihrer Herstellung sowie ihre Verwendung
FR2809011B1 (fr) *	2000-05-22	2002-11-15	Sederma Sa	Utilisation du beurre de karite incorpore dans les microcapsules fixees sur tout textile pour augmenter l'hydratation cutanee
DE20019711U1 (de) *	2000-11-20	2002-04-04	Söring GmbH, 25451 Quickborn	Ultraschall-Gerät zur Behandlung septischer Wunden
US7776314B2 (en)	2002-06-17	2010-08-17	Grunenthal Gmbh	Abuse-proofed dosage system
US8012136B2 (en) *	2003-05-20	2011-09-06	Optimyst Systems, Inc.	Ophthalmic fluid delivery device and method of operation
DE602004031829D1 (de) *	2003-05-20	2011-04-28	Collins	Ophthalmisches arzneimittelabgabesystem
US20070048228A1 (en)	2003-08-06	2007-03-01	Elisabeth Arkenau-Maric	Abuse-proofed dosage form
DE102004020220A1 (de) *	2004-04-22	2005-11-10	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
US8075872B2 (en)	2003-08-06	2011-12-13	Gruenenthal Gmbh	Abuse-proofed dosage form
DE102004032051A1 (de)	2004-07-01	2006-01-19	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
DE10361596A1 (de)	2003-12-24	2005-09-29	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE10336400A1 (de)	2003-08-06	2005-03-24	Grünenthal GmbH	Gegen Missbrauch gesicherte Darreichungsform
PL1658054T3 (pl) *	2003-08-06	2007-11-30	Gruenenthal Gmbh	Postać aplikacyjna zabezpieczona przed nadużyciem
DE102005005446A1 (de) *	2005-02-04	2006-08-10	Grünenthal GmbH	Bruchfeste Darreichungsformen mit retardierter Freisetzung
US7413690B1 (en)	2003-10-29	2008-08-19	The University Of Mississippi	Process and apparatus for producing spherical pellets using molten solid matrices
PL1691787T3 (pl) *	2003-12-04	2008-11-28	Pfizer Prod Inc	Sposób wytwarzania farmaceutycznych systemów wielocząstkowych
DE102004032049A1 (de) *	2004-07-01	2006-01-19	Grünenthal GmbH	Gegen Missbrauch gesicherte, orale Darreichungsform
DE102004032103A1 (de) *	2004-07-01	2006-01-19	Grünenthal GmbH	Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de) *	2005-02-04	2006-08-10	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US20080075811A1 (en) *	2006-09-23	2008-03-27	Peter Horlacher	Coated particles and their use
DE102007011485A1 (de)	2007-03-07	2008-09-11	Grünenthal GmbH	Darreichungsform mit erschwertem Missbrauch
EP2022557A1 (en) *	2007-08-06	2009-02-11	Laboratories Development LLC	A process for the preparation of granular frozen powder
EP2205221A2 (en) *	2007-10-23	2010-07-14	Koninklijke Philips Electronics N.V.	Methods for preparing polymer microparticles
EP2101131A1 (en)	2007-12-31	2009-09-16	Terruzzi Fercalx S.p.A.	Lyophilization method and system therefor
US20090212133A1 (en) *	2008-01-25	2009-08-27	Collins Jr James F	Ophthalmic fluid delivery device and method of operation
AU2009207796B2 (en)	2008-01-25	2014-03-27	Grunenthal Gmbh	Pharmaceutical dosage form
HRP20161307T1 (hr) *	2008-05-09	2016-12-02	Grünenthal GmbH	Postupak za pripravu praškaste formulacije međuproizvoda i konačni kruti oblik doziranja uz korištenje koraka zgrušavanja raspršivanjem
CA2765971C (en)	2009-07-22	2017-08-22	Gruenenthal Gmbh	Hot-melt extruded controlled release dosage form
PE20120631A1 (es)	2009-07-22	2012-06-06	Gruenenthal Chemie	Forma de dosificacion resistente a la manipulacion para opioides sensibles a la oxidacion
CN102821757B (zh)	2010-02-03	2016-01-20	格吕伦塔尔有限公司	通过挤出机制备粉末状药物组合物
KR20150031340A (ko)	2010-07-15	2015-03-23	코린시언 아프샐믹 인코포레이티드	안과용 약물 전달
US10154923B2 (en)	2010-07-15	2018-12-18	Eyenovia, Inc.	Drop generating device
CN103118642B (zh)	2010-07-15	2015-09-09	艾诺维亚股份有限公司	液滴生成装置
WO2012009702A1 (en)	2010-07-15	2012-01-19	Corinthian Ophthalmic, Inc.	Method and system for performing remote treatment and monitoring
AR082862A1 (es)	2010-09-02	2013-01-16	Gruenenthal Gmbh	Forma de dosificacion resistente a alteracion que comprende un polimero anionico
PL2611426T3 (pl)	2010-09-02	2014-09-30	Gruenenthal Gmbh	Postać dawkowania zawierająca nieorganiczne sole, odporna na zgniatanie
RU2449777C1 (ru) *	2010-12-20	2012-05-10	Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Новосибирский национальный исследовательский государственный университет" (Новосибирский государственный университет, НГУ)	Способ получения высокодисперсного парацетамола
HRP20171458T1 (hr)	2011-07-29	2017-11-17	Grünenthal GmbH	Tableta otporna na mijenjanje koja pruža neposredno oslobađanje lijeka
KR20140053159A (ko)	2011-07-29	2014-05-07	그뤼넨탈 게엠베하	즉시 약물 방출을 제공하는 탬퍼-저항성 정제
US20130150812A1 (en)	2011-12-12	2013-06-13	Corinthian Ophthalmic, Inc.	High modulus polymeric ejector mechanism, ejector device, and methods of use
JP6117249B2 (ja)	2012-02-28	2017-04-19	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	薬理学的に活性な化合物および陰イオン性ポリマーを含むタンパーレジスタント剤形
PT2838512T (pt)	2012-04-18	2018-11-09	Gruenenthal Gmbh	Forma farmacêutica resistente à adulteração e resistente à libertação inesperada de alta quantidade (dose-dumping)
US10064945B2 (en)	2012-05-11	2018-09-04	Gruenenthal Gmbh	Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
US9737490B2 (en)	2013-05-29	2017-08-22	Grünenthal GmbH	Tamper resistant dosage form with bimodal release profile
US9452271B2 (en)	2013-05-29	2016-09-27	General Electric Company	Nebulizer systems and methods
BR112015026549A2 (pt)	2013-05-29	2017-07-25	Gruenenthal Gmbh	forma de dosagem à prova de violação contendo uma ou mais partículas
EA032465B1 (ru)	2013-07-12	2019-05-31	Грюненталь Гмбх	Защищенная от применения не по назначению пероральная фармацевтическая лекарственная форма, содержащая этиленвинилацетатный полимер, и способ ее изготовления
HK1224189A1 (zh)	2013-11-26	2017-08-18	Grünenthal GmbH	通过低温研磨制备粉状药物组合物
EP3142646A1 (en)	2014-05-12	2017-03-22	Grünenthal GmbH	Tamper resistant immediate release capsule formulation comprising tapentadol
WO2015181059A1 (en)	2014-05-26	2015-12-03	Grünenthal GmbH	Multiparticles safeguarded against ethanolic dose-dumping
US20180310550A9 (en) *	2015-04-21	2018-11-01	Basf Se	Method for producing particles comprising a hydrocarbon wax in a continuous phase and a pesticide dispersed in the continuous phase by generating droplets with a vibrating nozzle
HK1246173A1 (zh)	2015-04-24	2018-09-07	Grünenthal GmbH	具有立即释放和对溶剂萃取的抗性的抗篡改剂型
WO2017042325A1 (en)	2015-09-10	2017-03-16	Grünenthal GmbH	Protecting oral overdose with abuse deterrent immediate release formulations
CN108623724A (zh) *	2017-03-17	2018-10-09	江苏华昌织物有限公司	用于信息素缓释的高分子微球的制备方法
CN111093742B (zh)	2017-06-10	2022-09-16	艾诺维亚股份有限公司	用于处理流体并将流体输送到眼睛的方法和设备
US12161585B2 (en)	2019-12-11	2024-12-10	Eyenovia, Inc.	Systems and devices for delivering fluids to the eye and methods of use

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2828206A (en) *	1954-02-24	1958-03-25	Roseuberg Adolf	Stabilized fat-soluble vitamins and methods of making same
US3078216A (en) *	1961-04-11	1963-02-19	American Cyanamid Co	Prolonged release oral pharmaceutical preparations
ES297425A1 (es) *	1963-03-04	1964-06-01	Merck & Company Incorporated	Procedimiento para preparar composiciones farmaceúticas en forma de tabletas de acción diferida
US3432593A (en) *	1963-09-18	1969-03-11	Key Pharm Inc	Delayed and sustained release type pharmaceutical preparation
US3922339A (en) *	1974-06-20	1975-11-25	Kv Pharm Co	Sustained release medicant
SE418247B (sv) *	1975-11-17	1981-05-18	Haessle Ab	Sett att framstella kroppar med reglerad frigoring av en aktiv komponent
DE2725849C3 (de) *	1977-06-08	1980-11-13	Hobeg Hochtemperaturreaktor-Brennelement Gmbh, 6450 Hanau	Vorrichtung zur Herstellung von kugelförmigen Teilchen
DK151608C (da) *	1982-08-13	1988-06-20	Benzon As Alfred	Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
US4657543A (en) *	1984-07-23	1987-04-14	Massachusetts Institute Of Technology	Ultrasonically modulated polymeric devices for delivering compositions
US4779806A (en) *	1984-07-23	1988-10-25	Massachusetts Institute Of Technology	Ultrasonically modulated polymeric devices for delivering compositions
FR2571980A1 (fr) *	1984-10-22	1986-04-25	Extramet Sa	Procede et dispositif de fabrication de micro-billes calibrees et micro-billes obtenues.
DE3639038C2 (de) *	1986-11-14	1997-02-06	Helmut Dr Lukas	Verwendung von S-(+)-Ibuprofen zur schnellen Behandlung humaner Schmerzen
US5019400A (en) *	1989-05-01	1991-05-28	Enzytech, Inc.	Very low temperature casting of controlled release microspheres
FR2657257B1 (fr) *	1990-01-19	1994-09-02	Rhone Poulenc Sante	Procede de preparation de medicaments sous forme de perles.
FR2664851B1 (fr) *	1990-07-20	1992-10-16	Oreal	Procede de compactage d'un melange pulverulent permettant d'obtenir un produit compact absorbant ou partiellement delitable et produit obtenu par ce procede.

1994
- 1994-08-03 IT ITBO940379A patent/IT1274879B/it active IP Right Grant
1995
- 1995-04-06 WO PCT/IT1995/000048 patent/WO1996003979A1/en not_active Ceased
- 1995-04-06 PT PT95913940T patent/PT726765E/pt unknown
- 1995-04-06 DE DE69521406T patent/DE69521406T2/de not_active Expired - Lifetime
- 1995-04-06 ES ES95913940T patent/ES2159632T3/es not_active Expired - Lifetime
- 1995-04-06 EP EP95913940A patent/EP0726765B1/en not_active Expired - Lifetime
- 1995-04-06 DK DK95913940T patent/DK0726765T3/da active
- 1995-04-06 BR BR9506305A patent/BR9506305A/pt not_active IP Right Cessation
- 1995-04-06 JP JP8506370A patent/JPH09503441A/ja active Pending
- 1995-04-06 CN CNB951908510A patent/CN1213735C/zh not_active Expired - Fee Related
- 1995-04-06 US US08/624,475 patent/US5707636A/en not_active Expired - Lifetime
- 1995-04-06 RU RU96112192A patent/RU2142792C1/ru not_active IP Right Cessation
- 1995-04-06 AT AT95913940T patent/ATE202279T1/de not_active IP Right Cessation
- 1995-04-06 AU AU21137/95A patent/AU693539B2/en not_active Ceased
- 1995-04-06 CA CA002173221A patent/CA2173221A1/en not_active Abandoned
- 1995-04-06 KR KR1019960701827A patent/KR100348935B1/ko not_active Expired - Fee Related
- 1995-07-24 TW TW084107653A patent/TW343149B/zh active
1996
- 1996-04-02 MX MX9601279A patent/MX9601279A/es not_active IP Right Cessation
2001
- 2001-09-06 GR GR20010401401T patent/GR3036548T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU693539B2 (en)	1998-07-02
KR960704529A (ko)	1996-10-09
CN1213735C (zh)	2005-08-10
DE69521406D1 (de)	2001-07-26
ITBO940379A1 (it)	1996-02-03
RU2142792C1 (ru)	1999-12-20
DK0726765T3 (da)	2001-10-15
WO1996003979A1 (en)	1996-02-15
KR100348935B1 (ko)	2002-12-28
TW343149B (en)	1998-10-21
AU2113795A (en)	1996-03-04
ITBO940379A0 (it)	1994-08-03
JPH09503441A (ja)	1997-04-08
IT1274879B (it)	1997-07-25
US5707636A (en)	1998-01-13
PT726765E (pt)	2001-12-28
ES2159632T3 (es)	2001-10-16
CA2173221A1 (en)	1996-02-15
ATE202279T1 (de)	2001-07-15
CN1135175A (zh)	1996-11-06
DE69521406T2 (de)	2002-05-02
MX9601279A (es)	1998-11-30
EP0726765A1 (en)	1996-08-21
GR3036548T3 (en)	2001-12-31
EP0726765B1 (en)	2001-06-20

Publication	Publication Date	Title
BR9506305A (pt)	1997-08-05	Aparelho e processo para preparação de formas sólidas com desprendimento controlado do ingrediente ativo
EE03202B1 (et)	1999-08-16	Intravaginaalne manustussüsteem ja selle valmistamismeetod
DE59607490D1 (de)	2001-09-20	Verfahren zur herstellung von wirkstoffzubereitungen in form einer festen lösung des wirkstoffs in einer polymermatrix
SE9604793D0 (sv)	1996-12-20	New polymorphs
DE69230040D1 (de)	1999-10-28	Biokompatibles implantat für die zeitliche abstimmung der ovulation von stuten
DE69115280D1 (de)	1996-01-18	Indolderivate, die die leukotrienbiosynthese hemmen.
BR9703302A (pt)	2001-03-20	Aparelho e método para a geração e uso de ìons férricos
IL127592A0 (en)	1999-10-28	Method and apparatus for producing plastic sleeves
ES2177644T3 (es)	2002-12-16	Procedimiento para la resolucion de etodolac utilizando derivados de glucamina.
ES2162929T3 (es)	2002-01-16	Procedimiento para la preparacion de 2-(1-azabiciclo(2.2.2)oct-3-il)-2,4,5,6-tetrahidro-1h-benz(de)isoquinolin-1-ona y producto intermediario.
ES8501750A1 (es)	1984-12-01	Un procedimiento para la preparacion de 4-aril-4-piperidincarbinoles.
BR9807227B1 (pt)	2012-07-24	composiÇço herbicida para tratamento foliar, processo de eliminaÇço e uso de referida composiÇço herbicida.
ATE215084T1 (de)	2002-04-15	Imidazopyridin-azolidinone
ATE152722T1 (de)	1997-05-15	Verfahren zur herstellung von 9-(2-hydroxy)- ethoxy-guanin
ATE213782T1 (de)	2002-03-15	Verfahren zur biotransformation von colchicinoid- verbindungen in die entsprechenden 3- glycosylderivate
BR9508021A (pt)	2004-04-20	Composição farmacêutica para o tratamento de distúrbios esquizofrênicos, uso de um agente imunossupressor, e, processo de tratamento de um paciente esquizofrênico
ES2163001T3 (es)	2002-01-16	Nuevos derivados de borneol, procedimiento para su preparacion y su utilizacion farmaceutica.
MXPA04010915A (es)	2006-03-08	Base y procedimiento de conocimiento de recursos humanos dinamicos.
ES2136615T3 (es)	1999-12-01	Nuevos inhibidores de glucohidrolasa utiles como agentes antidiabeticos, antiviricos y antimetastasicos.
PL318292A1 (en)	1997-06-09	Application of selegyline in treating epileptic seizures
AR010304A1 (es)	2000-06-07	Compuestos de dimesilato de cis-1-(3-etoxifenil)-1-4-fenilpiperazin-1-il) -4-metilciclohexano; procedimiento para su preparacion y composicionfarmaceutica
BR9507623A (pt)	1997-10-07	Composto processo e precursor para á preparação do mesmo
SE9404438D0 (sv)	1994-12-21	New process
MXPA03010633A (es)	2004-03-09	Metodo para trastornos de resequedad de ojos.
ES2040362T3 (es)	1995-04-01	Procedimiento para la preparacion de 2-(benzhidrilsulfonil)acetamida.

Legal Events

Date	Code	Title	Description
2002-05-21	FF	Decision: intention to grant
2002-09-17	FG9A	Patent or certificate of addition granted
2011-04-26	B24C	Patent annual fee: request for for restoration	Free format text: REFERENTE A 11A, 12A, 13A, 14A, 15A E 16A ANUIDADE(S).
2014-04-08	B24H	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi)
2020-12-01	B24F	Patent annual fee: publication cancelled	Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2257 DE 08/04/2014 POR TER SIDO INDEVIDA.
2020-12-15	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE AS 11A, 12A, 13A, 14A, 15A E 16A ANUIDADES.
2021-03-30	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)	Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2606 DE 15-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.