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BG21226A3 - Метод за получаване на n/хетероарилметил/ д7 -де- зокси- нормофини и ниркодеини - Google Patents

Метод за получаване на n/хетероарилметил/ д7 -де- зокси- нормофини и ниркодеини

Info

Publication number
BG21226A3
BG21226A3 BG025615A BG2561574A BG21226A3 BG 21226 A3 BG21226 A3 BG 21226A3 BG 025615 A BG025615 A BG 025615A BG 2561574 A BG2561574 A BG 2561574A BG 21226 A3 BG21226 A3 BG 21226A3
Authority
BG
Bulgaria
Prior art keywords
normophines
nircodeines
heteroarylmethyl
desoxy
preparation
Prior art date
Application number
BG025615A
Other languages
English (en)
Inventor
Gerhard Walther
Herbert Merz
Adolf Langbein
Klaus Stockhaus
Original Assignee
C.H.Boehringer Sohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn
Publication of BG21226A3 publication Critical patent/BG21226A3/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Emergency Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Networks Using Active Elements (AREA)
BG025615A 1972-09-14 1974-01-28 Метод за получаване на n/хетероарилметил/ д7 -де- зокси- нормофини и ниркодеини BG21226A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2245141A DE2245141A1 (de) 1972-09-14 1972-09-14 Neue n-(heteroarylmethyl)-desoxynormorphine und -norcodeine, deren saeureadditionssalze, verfahren zu deren herstellung sowie deren verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
BG21226A3 true BG21226A3 (bg) 1976-03-20

Family

ID=5856355

Family Applications (8)

Application Number Title Priority Date Filing Date
BG025613A BG21224A3 (bg) 1972-09-14 1973-09-12 Метод за получаване на n/ хетероарил метил- / -д7 дезокси норморфини м норкодеини
BG025619A BG21230A3 (bg) 1972-09-14 1973-09-12 Метод за получаване на n/ хетероарилметил/ д7- дезокси - норморфини и- норкодеини
BG025618A BG21229A3 (bg) 1972-09-14 1973-09-12 Метод за получаване на n/ хетероарилметил/ д7 дезокси- норморфини- норкодеини
BG24524A BG21412A3 (bg) 1972-09-14 1973-09-12
BG25617A BG21228A3 (bg) 1972-09-14 1973-09-12
BG025614A BG21225A3 (bg) 1972-09-14 1973-09-12 Метод за получаване на n / хетероарил метил/-д7- дезокси- норморфини и наркодеини
BG025616A BG21227A3 (bg) 1972-09-14 1973-09-12 Метод за получаване на n/ хетепоарилметил/ д7- дезокси- норморфини и норкодеини
BG025615A BG21226A3 (bg) 1972-09-14 1974-01-28 Метод за получаване на n/хетероарилметил/ д7 -де- зокси- нормофини и ниркодеини

Family Applications Before (7)

Application Number Title Priority Date Filing Date
BG025613A BG21224A3 (bg) 1972-09-14 1973-09-12 Метод за получаване на n/ хетероарил метил- / -д7 дезокси норморфини м норкодеини
BG025619A BG21230A3 (bg) 1972-09-14 1973-09-12 Метод за получаване на n/ хетероарилметил/ д7- дезокси - норморфини и- норкодеини
BG025618A BG21229A3 (bg) 1972-09-14 1973-09-12 Метод за получаване на n/ хетероарилметил/ д7 дезокси- норморфини- норкодеини
BG24524A BG21412A3 (bg) 1972-09-14 1973-09-12
BG25617A BG21228A3 (bg) 1972-09-14 1973-09-12
BG025614A BG21225A3 (bg) 1972-09-14 1973-09-12 Метод за получаване на n / хетероарил метил/-д7- дезокси- норморфини и наркодеини
BG025616A BG21227A3 (bg) 1972-09-14 1973-09-12 Метод за получаване на n/ хетепоарилметил/ д7- дезокси- норморфини и норкодеини

Country Status (24)

Country Link
US (1) US3928359A (bg)
JP (1) JPS4966700A (bg)
AT (1) AT326281B (bg)
BE (1) BE804836A (bg)
BG (8) BG21224A3 (bg)
CH (7) CH591490A5 (bg)
CS (8) CS168673B2 (bg)
DD (1) DD109384A5 (bg)
DE (1) DE2245141A1 (bg)
ES (8) ES418563A1 (bg)
FI (1) FI55512C (bg)
FR (1) FR2199982B1 (bg)
GB (1) GB1449222A (bg)
HU (1) HU166367B (bg)
IE (1) IE38320B1 (bg)
IL (1) IL43216A (bg)
NL (1) NL7312621A (bg)
NO (1) NO139482C (bg)
PL (8) PL91808B1 (bg)
RO (2) RO63003A (bg)
SE (1) SE413510B (bg)
SU (8) SU498911A3 (bg)
YU (2) YU243973A (bg)
ZA (1) ZA737289B (bg)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4236008A (en) * 1978-09-19 1980-11-25 E. I. Du Pont De Nemours And Company Fluorination of precursors for fluorine analogs of hydrocodone and oxycodone
US4241065A (en) * 1979-07-02 1980-12-23 E. I. Du Pont De Nemours And Company Fluoro analogs of hydrocodone and oxycodone useful as analgesics, narcotic antagonists or both
CA2319627A1 (en) 1998-01-29 1999-08-05 Polychip Pharmaceuticals Pty. Ltd. Therapeutic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2107989A1 (de) * 1971-02-19 1972-09-07 Boehringer Sohn Ingelheim N-(Furyl-methy])-morphinane, deren Säureadditionssalze sowie Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
SU503523A3 (ru) 1976-02-15
PL90720B1 (bg) 1977-01-31
CS168675B2 (bg) 1976-06-29
SU498911A3 (ru) 1976-01-05
ES430197A1 (es) 1976-10-16
CS168673B2 (bg) 1976-06-29
CS168679B2 (bg) 1976-06-29
SU505366A3 (ru) 1976-02-28
ES430199A1 (es) 1976-10-16
FR2199982A1 (bg) 1974-04-19
CS168680B2 (bg) 1976-06-29
SU503524A3 (ru) 1976-02-15
ATA761673A (de) 1975-02-15
BG21412A3 (bg) 1976-05-20
PL91837B1 (bg) 1977-03-31
BG21228A3 (bg) 1976-03-20
GB1449222A (en) 1976-09-15
CH591490A5 (bg) 1977-09-30
BE804836A (fr) 1974-03-13
RO70193A (ro) 1981-04-30
HU166367B (bg) 1975-03-28
JPS4966700A (bg) 1974-06-27
DD109384A5 (bg) 1974-11-05
DE2245141A1 (de) 1974-03-21
IL43216A (en) 1976-07-30
FI55512C (fi) 1979-08-10
BG21229A3 (bg) 1976-03-20
ES430200A1 (es) 1976-10-16
IL43216A0 (en) 1973-11-28
CH590287A5 (bg) 1977-07-29
NL7312621A (bg) 1974-03-18
SE413510B (sv) 1980-06-02
NO139482C (no) 1979-03-21
NO139482B (no) 1978-12-11
SU506299A3 (ru) 1976-03-05
PL91807B1 (bg) 1977-03-31
AU6030173A (en) 1975-03-13
RO63003A (fr) 1978-05-15
FI55512B (fi) 1979-04-30
FR2199982B1 (bg) 1977-01-28
PL91829B1 (bg) 1977-03-31
PL87721B1 (bg) 1976-07-31
ES430198A1 (es) 1976-10-16
CH589090A5 (bg) 1977-06-30
CS168676B2 (bg) 1976-06-29
CH605958A5 (bg) 1978-10-13
CH589089A5 (bg) 1977-06-30
BG21230A3 (bg) 1976-03-20
SU509239A3 (ru) 1976-03-30
CS168678B2 (bg) 1976-06-29
PL91809B1 (bg) 1977-03-31
IE38320B1 (en) 1978-02-15
CH591491A5 (bg) 1977-09-30
PL91808B1 (bg) 1977-03-31
ES430201A1 (es) 1976-10-16
CS168674B2 (bg) 1976-06-29
BG21225A3 (bg) 1976-03-20
IE38320L (en) 1974-03-14
ES430203A1 (es) 1976-10-16
YU243973A (en) 1982-05-31
BG21227A3 (bg) 1976-03-20
AT326281B (de) 1975-12-10
CH589088A5 (bg) 1977-06-30
YU254879A (en) 1983-01-21
SU528878A3 (ru) 1976-09-15
ES418563A1 (es) 1976-05-01
BG21224A3 (bg) 1976-03-20
ES430202A1 (es) 1976-10-16
SU520049A3 (ru) 1976-06-30
ZA737289B (en) 1975-05-28
US3928359A (en) 1975-12-23
PL91836B1 (bg) 1977-03-31
CS168677B2 (bg) 1976-06-29

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