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BG105004A - Carbapenem derivatives, utilization thereof and intermediate compounds of the same - Google Patents

Carbapenem derivatives, utilization thereof and intermediate compounds of the same

Info

Publication number
BG105004A
BG105004A BG105004A BG10500400A BG105004A BG 105004 A BG105004 A BG 105004A BG 105004 A BG105004 A BG 105004A BG 10500400 A BG10500400 A BG 10500400A BG 105004 A BG105004 A BG 105004A
Authority
BG
Bulgaria
Prior art keywords
same
utilization
intermediate compounds
carbapenem derivatives
compounds
Prior art date
Application number
BG105004A
Other languages
Bulgarian (bg)
English (en)
Inventor
Hiroshi Matsui
Hajime Takashima
Original Assignee
Kyoto Pharmaceutical Industries, Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10122499A external-priority patent/JP2000344772A/ja
Priority claimed from JP10203730A external-priority patent/JP2000344773A/ja
Application filed by Kyoto Pharmaceutical Industries, Ltd filed Critical Kyoto Pharmaceutical Industries, Ltd
Publication of BG105004A publication Critical patent/BG105004A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BG105004A 1998-05-01 2000-11-29 Carbapenem derivatives, utilization thereof and intermediate compounds of the same BG105004A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10122499A JP2000344772A (ja) 1998-05-01 1998-05-01 カルバペネム誘導体、その用途およびその中間体化合物
JP10203730A JP2000344773A (ja) 1998-07-17 1998-07-17 カルバペネム誘導体、およびその用途並びにその中間体化合物
PCT/JP1999/002301 WO1999057121A1 (en) 1998-05-01 1999-04-28 Carbapenem derivatives, utilization thereof and intermediate compounds of the same

Publications (1)

Publication Number Publication Date
BG105004A true BG105004A (en) 2001-08-31

Family

ID=26459604

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105004A BG105004A (en) 1998-05-01 2000-11-29 Carbapenem derivatives, utilization thereof and intermediate compounds of the same

Country Status (24)

Country Link
US (1) US6410525B1 (pt)
EP (1) EP1078927B1 (pt)
KR (1) KR100589030B1 (pt)
CN (1) CN1163494C (pt)
AR (1) AR018335A1 (pt)
AT (1) ATE337321T1 (pt)
AU (1) AU760386B2 (pt)
BG (1) BG105004A (pt)
BR (1) BR9910098A (pt)
CA (1) CA2330641A1 (pt)
CO (1) CO5011051A1 (pt)
CZ (1) CZ292623B6 (pt)
DE (1) DE69932927D1 (pt)
HU (1) HUP0101735A3 (pt)
ID (1) ID27081A (pt)
NO (1) NO20005480L (pt)
NZ (1) NZ508493A (pt)
PL (1) PL343728A1 (pt)
RU (1) RU2222540C2 (pt)
SK (1) SK16382000A3 (pt)
TR (1) TR200003199T2 (pt)
TW (1) TW528750B (pt)
WO (1) WO1999057121A1 (pt)
YU (1) YU66700A (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2414311C (en) 2000-07-19 2008-01-08 F. Hoffmann-La Roche Ag Pyrrolidine derivatives as inhibitors of endothelin-converting enzyme
SK15822003A3 (sk) * 2001-05-21 2004-06-08 Kyoto Pharmaceutical Industries, Ltd. Karbapenémový derivát
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
EP1443047A4 (en) * 2001-11-05 2005-04-27 Sumitomo Pharma NEW CARBAPENE COMPOUNDS
CA2519794A1 (en) 2003-04-08 2004-10-21 Sumitomo Pharmaceuticals Co., Ltd. Novel carbapenem compounds
US20070265242A1 (en) * 2004-09-03 2007-11-15 Makoto Sunagawa Novel Carbapenem Compound
JPWO2006103999A1 (ja) * 2005-03-25 2008-09-04 大日本住友製薬株式会社 新規なカルバペネム化合物
RU2008108215A (ru) * 2005-08-31 2009-10-10 Вайет (Us) 9-аминокарбонилзамещенные производные глицилциклинов
CN101376656A (zh) * 2007-08-30 2009-03-04 山东轩竹医药科技有限公司 培南衍生物
EP2968274B1 (en) 2013-03-15 2019-10-16 Kala Pharmaceuticals, Inc. Meropenem derivatives and uses thereof
JP7437847B2 (ja) * 2018-10-01 2024-02-26 アリクサ ファーマシューティカルズ、インコーポレイテッド レレバクタムの誘導体およびその使用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
US4539332A (en) * 1983-11-14 1985-09-03 Merck & Co., Inc. 2,5-Diaryl tetrahydrofurans and analogs thereof as PAF-antagonists
JPS60233076A (ja) * 1984-05-03 1985-11-19 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物およびその製造法
FI81576C (fi) 1984-12-25 1990-11-12 Sankyo Co Foerfarande foer framstaellning av derivat av 6-(1-hydroxietyl)-2-(1,2-disubstituerade-4-pyrrolidinyltio)-2- karbapenem-3-karboxylsyra, vilka aer anvaendbara som laekemedel.
IE60588B1 (en) 1986-07-30 1994-07-27 Sumitomo Pharma Carbapenem compound in crystalline form, and its production and use
DK175029B1 (da) 1988-04-01 2004-05-03 Sankyo Co 2-(heterocyclylthio)carbapenemderivater, farmaceutiske midler indeholdende dem, fremgangsmåde til fremstilling deraf samt deres anvendelse som antibiotika
US5242914A (en) 1988-04-01 1993-09-07 Sankyo Company, Limited 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics
AU646012B2 (en) * 1990-02-23 1994-02-03 Sankyo Company Limited Carbapenem derivatives having antibiotic activity, their preparation and their use
AU644008B2 (en) 1990-08-10 1993-12-02 Sumitomo Pharmaceuticals Company, Limited Beta-lactam compounds, and their production and use
US5712267A (en) 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
JP3048196B2 (ja) * 1991-06-20 2000-06-05 第一製薬株式会社 カルバペネム誘導体
US5360798A (en) 1991-07-04 1994-11-01 Shionogi Seiyaku Kabushiki Kaisha Aminooxypyrrolidinylthiocarbapenem compounds
DK0882728T3 (da) 1995-12-21 2003-01-06 Sankyo Co 1-methylcarbapenemderivater

Also Published As

Publication number Publication date
ID27081A (id) 2001-02-22
HUP0101735A2 (hu) 2001-12-28
CN1163494C (zh) 2004-08-25
CZ292623B6 (cs) 2003-11-12
EP1078927A1 (en) 2001-02-28
NO20005480L (no) 2000-12-20
ATE337321T1 (de) 2006-09-15
NO20005480D0 (no) 2000-10-31
AU760386B2 (en) 2003-05-15
AR018335A1 (es) 2001-11-14
DE69932927D1 (de) 2006-10-05
CZ20003954A3 (cs) 2001-04-11
KR100589030B1 (ko) 2006-06-13
CN1307578A (zh) 2001-08-08
NZ508493A (en) 2002-06-28
CA2330641A1 (en) 1999-11-11
SK16382000A3 (sk) 2001-05-10
CO5011051A1 (es) 2001-02-28
WO1999057121A1 (en) 1999-11-11
TR200003199T2 (tr) 2001-03-21
US6410525B1 (en) 2002-06-25
EP1078927A4 (en) 2003-01-08
BR9910098A (pt) 2000-12-26
YU66700A (sh) 2003-01-31
TW528750B (en) 2003-04-21
KR20010043196A (ko) 2001-05-25
HUP0101735A3 (en) 2002-02-28
RU2222540C2 (ru) 2004-01-27
AU3627299A (en) 1999-11-23
EP1078927B1 (en) 2006-08-23
PL343728A1 (en) 2001-09-10

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