HUP0101735A3 - Carbapenem derivatives, pharmaceutical compositions thereof and intermediate compounds - Google Patents

Carbapenem derivatives, pharmaceutical compositions thereof and intermediate compounds

Info

Publication number: HUP0101735A3
Authority: HU; Hungary
Prior art keywords: pharmaceutical compositions; intermediate compounds; carbapenem derivatives; carbapenem; derivatives
Prior art date: 1998-05-01

Application number

HU0101735A

Other languages

English (en)

Original Assignee

Kyoto Pharma Ind

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-01

Filing date

1999-04-28

Publication date

2002-02-28

1998-05-01 Priority claimed from JP10122499A external-priority patent/JP2000344772A/ja

1998-07-17 Priority claimed from JP10203730A external-priority patent/JP2000344773A/ja

1999-04-28 Application filed by Kyoto Pharma Ind filed Critical Kyoto Pharma Ind

2001-12-28 Publication of HUP0101735A2 publication Critical patent/HUP0101735A2/hu

2002-02-28 Publication of HUP0101735A3 publication Critical patent/HUP0101735A3/hu

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

HU0101735A 1998-05-01 1999-04-28 Carbapenem derivatives, pharmaceutical compositions thereof and intermediate compounds HUP0101735A3 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP10122499A JP2000344772A (ja)	1998-05-01	1998-05-01	カルバペネム誘導体、その用途およびその中間体化合物
JP10203730A JP2000344773A (ja)	1998-07-17	1998-07-17	カルバペネム誘導体、およびその用途並びにその中間体化合物
PCT/JP1999/002301 WO1999057121A1 (en)	1998-05-01	1999-04-28	Carbapenem derivatives, utilization thereof and intermediate compounds of the same

Publications (2)

Publication Number	Publication Date
HUP0101735A2 HUP0101735A2 (hu)	2001-12-28
HUP0101735A3 true HUP0101735A3 (en)	2002-02-28

Family

ID=26459604

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0101735A HUP0101735A3 (en)	1998-05-01	1999-04-28	Carbapenem derivatives, pharmaceutical compositions thereof and intermediate compounds

Country Status (24)

Country	Link
US (1)	US6410525B1 (hu)
EP (1)	EP1078927B1 (hu)
KR (1)	KR100589030B1 (hu)
CN (1)	CN1163494C (hu)
AR (1)	AR018335A1 (hu)
AT (1)	ATE337321T1 (hu)
AU (1)	AU760386B2 (hu)
BG (1)	BG105004A (hu)
BR (1)	BR9910098A (hu)
CA (1)	CA2330641A1 (hu)
CO (1)	CO5011051A1 (hu)
CZ (1)	CZ292623B6 (hu)
DE (1)	DE69932927D1 (hu)
HU (1)	HUP0101735A3 (hu)
ID (1)	ID27081A (hu)
NO (1)	NO20005480L (hu)
NZ (1)	NZ508493A (hu)
PL (1)	PL343728A1 (hu)
RU (1)	RU2222540C2 (hu)
SK (1)	SK16382000A3 (hu)
TR (1)	TR200003199T2 (hu)
TW (1)	TW528750B (hu)
WO (1)	WO1999057121A1 (hu)
YU (1)	YU66700A (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2414311C (en)	2000-07-19	2008-01-08	F. Hoffmann-La Roche Ag	Pyrrolidine derivatives as inhibitors of endothelin-converting enzyme
SK15822003A3 (sk) *	2001-05-21	2004-06-08	Kyoto Pharmaceutical Industries, Ltd.	Karbapenémový derivát
US8048917B2 (en)	2005-04-06	2011-11-01	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en)	2001-06-11	2007-06-19	Xenoport, Inc.	Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US6818787B2 (en)	2001-06-11	2004-11-16	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en)	2001-06-11	2007-03-06	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
EP1443047A4 (en) *	2001-11-05	2005-04-27	Sumitomo Pharma	NEW CARBAPENE COMPOUNDS
CA2519794A1 (en)	2003-04-08	2004-10-21	Sumitomo Pharmaceuticals Co., Ltd.	Novel carbapenem compounds
US20070265242A1 (en) *	2004-09-03	2007-11-15	Makoto Sunagawa	Novel Carbapenem Compound
JPWO2006103999A1 (ja) *	2005-03-25	2008-09-04	大日本住友製薬株式会社	新規なカルバペネム化合物
RU2008108215A (ru) *	2005-08-31	2009-10-10	Вайет (Us)	9-аминокарбонилзамещенные производные глицилциклинов
CN101376656A (zh) *	2007-08-30	2009-03-04	山东轩竹医药科技有限公司	培南衍生物
EP2968274B1 (en)	2013-03-15	2019-10-16	Kala Pharmaceuticals, Inc.	Meropenem derivatives and uses thereof
JP7437847B2 (ja) *	2018-10-01	2024-02-26	アリクサファーマシューティカルズ、インコーポレイテッド	レレバクタムの誘導体およびその使用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1283906C (en)	1983-05-09	1991-05-07	Makoto Sunagawa	.beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
US4539332A (en) *	1983-11-14	1985-09-03	Merck & Co., Inc.	2,5-Diaryl tetrahydrofurans and analogs thereof as PAF-antagonists
JPS60233076A (ja) *	1984-05-03	1985-11-19	Sumitomo Chem Co Ltd	新規なβ−ラクタム化合物およびその製造法
FI81576C (fi)	1984-12-25	1990-11-12	Sankyo Co	Foerfarande foer framstaellning av derivat av 6-(1-hydroxietyl)-2-(1,2-disubstituerade-4-pyrrolidinyltio)-2- karbapenem-3-karboxylsyra, vilka aer anvaendbara som laekemedel.
IE60588B1 (en)	1986-07-30	1994-07-27	Sumitomo Pharma	Carbapenem compound in crystalline form, and its production and use
DK175029B1 (da)	1988-04-01	2004-05-03	Sankyo Co	2-(heterocyclylthio)carbapenemderivater, farmaceutiske midler indeholdende dem, fremgangsmåde til fremstilling deraf samt deres anvendelse som antibiotika
US5242914A (en)	1988-04-01	1993-09-07	Sankyo Company, Limited	2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics
AU646012B2 (en) *	1990-02-23	1994-02-03	Sankyo Company Limited	Carbapenem derivatives having antibiotic activity, their preparation and their use
AU644008B2 (en)	1990-08-10	1993-12-02	Sumitomo Pharmaceuticals Company, Limited	Beta-lactam compounds, and their production and use
US5712267A (en)	1991-06-04	1998-01-27	Sankyo Company,. Limited	Carbapenem derivatives, their preparation and their use as antibiotics
JP3048196B2 (ja) *	1991-06-20	2000-06-05	第一製薬株式会社	カルバペネム誘導体
US5360798A (en)	1991-07-04	1994-11-01	Shionogi Seiyaku Kabushiki Kaisha	Aminooxypyrrolidinylthiocarbapenem compounds
DK0882728T3 (da)	1995-12-21	2003-01-06	Sankyo Co	1-methylcarbapenemderivater

1999
- 1999-04-28 EP EP99918272A patent/EP1078927B1/en not_active Expired - Lifetime
- 1999-04-28 RU RU2000130224/04A patent/RU2222540C2/ru not_active IP Right Cessation
- 1999-04-28 ID IDW20002432A patent/ID27081A/id unknown
- 1999-04-28 AU AU36272/99A patent/AU760386B2/en not_active Ceased
- 1999-04-28 SK SK1638-2000A patent/SK16382000A3/sk unknown
- 1999-04-28 US US09/674,363 patent/US6410525B1/en not_active Expired - Fee Related
- 1999-04-28 HU HU0101735A patent/HUP0101735A3/hu unknown
- 1999-04-28 WO PCT/JP1999/002301 patent/WO1999057121A1/ja not_active Ceased
- 1999-04-28 NZ NZ508493A patent/NZ508493A/en unknown
- 1999-04-28 PL PL99343728A patent/PL343728A1/xx not_active IP Right Cessation
- 1999-04-28 CA CA002330641A patent/CA2330641A1/en not_active Abandoned
- 1999-04-28 YU YU66700A patent/YU66700A/sh unknown
- 1999-04-28 CN CNB998080306A patent/CN1163494C/zh not_active Expired - Fee Related
- 1999-04-28 DE DE69932927T patent/DE69932927D1/de not_active Expired - Lifetime
- 1999-04-28 KR KR1020007012121A patent/KR100589030B1/ko not_active Expired - Fee Related
- 1999-04-28 BR BR9910098-3A patent/BR9910098A/pt not_active Application Discontinuation
- 1999-04-28 TR TR2000/03199T patent/TR200003199T2/xx unknown
- 1999-04-28 AT AT99918272T patent/ATE337321T1/de not_active IP Right Cessation
- 1999-04-28 CZ CZ20003954A patent/CZ292623B6/cs not_active IP Right Cessation
- 1999-04-29 TW TW088106898A patent/TW528750B/zh not_active IP Right Cessation
- 1999-04-30 AR ARP990102033A patent/AR018335A1/es not_active Application Discontinuation
- 1999-04-30 CO CO99026262A patent/CO5011051A1/es unknown
2000
- 2000-10-31 NO NO20005480A patent/NO20005480L/no not_active Application Discontinuation
- 2000-11-29 BG BG105004A patent/BG105004A/xx unknown

Also Published As

Publication number	Publication date
ID27081A (id)	2001-02-22
HUP0101735A2 (hu)	2001-12-28
CN1163494C (zh)	2004-08-25
CZ292623B6 (cs)	2003-11-12
EP1078927A1 (en)	2001-02-28
NO20005480L (no)	2000-12-20
ATE337321T1 (de)	2006-09-15
BG105004A (en)	2001-08-31
NO20005480D0 (no)	2000-10-31
AU760386B2 (en)	2003-05-15
AR018335A1 (es)	2001-11-14
DE69932927D1 (de)	2006-10-05
CZ20003954A3 (cs)	2001-04-11
KR100589030B1 (ko)	2006-06-13
CN1307578A (zh)	2001-08-08
NZ508493A (en)	2002-06-28
CA2330641A1 (en)	1999-11-11
SK16382000A3 (sk)	2001-05-10
CO5011051A1 (es)	2001-02-28
WO1999057121A1 (en)	1999-11-11
TR200003199T2 (tr)	2001-03-21
US6410525B1 (en)	2002-06-25
EP1078927A4 (en)	2003-01-08
BR9910098A (pt)	2000-12-26
YU66700A (sh)	2003-01-31
TW528750B (en)	2003-04-21
KR20010043196A (ko)	2001-05-25
RU2222540C2 (ru)	2004-01-27
AU3627299A (en)	1999-11-23
EP1078927B1 (en)	2006-08-23
PL343728A1 (en)	2001-09-10

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PT1466615E (pt)	2009-09-07	Composição farmacêutica
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IL147214A0 (en)	2002-08-14	1-methylcarbapenem derivatives and pharmaceutical compositions containing the same
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GB9818591D0 (en)	1998-10-21	Pharmaceutical composition
HUP0101735A3 (en)	2002-02-28	Carbapenem derivatives, pharmaceutical compositions thereof and intermediate compounds
GB9809213D0 (en)	1998-07-01	Pharmaceutical compositions
AU3192500A (en)	2000-10-04	Substituted proline derivatives and medicinal compositions containing the same
HUP0103184A3 (en)	2002-05-28	Sulfonyl-biphenyl-methyl-substituted imidazole derivatives, their use and pharmaceutical compositions containing them
HUP0104146A3 (en)	2002-10-28	Pyrano, piperidino, and thiapyrano compounds, pharmaceutical compositions thereof and their intermediates
AUPP332898A0 (en)	1998-05-28	Pharmaceutical composition
HRP20000530B1 (en)	2003-10-31	Pharmaceutical compositions