ATE394401T1 - Diazabicycloderivate als nikotin-acetylcholin- rezeptorliganden - Google Patents

Diazabicycloderivate als nikotin-acetylcholin- rezeptorliganden

Info

Publication number: ATE394401T1
Authority: AT; Austria
Prior art keywords: nicotine; acetylcholine receptor; receptor ligands; diazabicyclo derivatives; diazabicyclo
Prior art date: 1999-01-29

Application number

AT03017562T

Other languages

English (en)

Inventor

William H Bunnelle

Cristina Daniela Barlocco

Jerome F Daanen

Michael J Dart

Michael D Meyer

Keith B Ryther

Michael R Schrimpf

Kevin B Sippy

Richard B Toupence

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-29

Filing date

2000-01-25

Publication date

2008-05-15

2000-01-25 Application filed by Abbott Lab filed Critical Abbott Lab

2008-05-15 Application granted granted Critical

2008-05-15 Publication of ATE394401T1 publication Critical patent/ATE394401T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Anesthesiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Gynecology & Obstetrics (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT03017562T 1999-01-29 2000-01-25 Diazabicycloderivate als nikotin-acetylcholin- rezeptorliganden ATE394401T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US23983899A	1999-01-29	1999-01-29

Publications (1)

Publication Number	Publication Date
ATE394401T1 true ATE394401T1 (de)	2008-05-15

Family

ID=22903947

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT03017562T ATE394401T1 (de)	1999-01-29	2000-01-25	Diazabicycloderivate als nikotin-acetylcholin- rezeptorliganden
AT00906998T ATE253067T1 (de)	1999-01-29	2000-01-25	Diazabicyloderivate als nikotin-acetylcholin- rezeptorliganden

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT00906998T ATE253067T1 (de)	1999-01-29	2000-01-25	Diazabicyloderivate als nikotin-acetylcholin- rezeptorliganden

Country Status (26)

Country	Link
EP (2)	EP1359152B1 (de)
JP (1)	JP4676062B2 (de)
KR (1)	KR20010101725A (de)
CN (2)	CN1345320A (de)
AR (1)	AR034538A1 (de)
AT (2)	ATE394401T1 (de)
AU (1)	AU773795B2 (de)
BG (1)	BG105836A (de)
BR (1)	BR0007664A (de)
CA (1)	CA2361525C (de)
CO (1)	CO5150231A1 (de)
CZ (1)	CZ20012716A3 (de)
DE (2)	DE60038823D1 (de)
DK (1)	DK1147112T3 (de)
ES (2)	ES2209825T3 (de)
HK (1)	HK1043116B (de)
HU (1)	HUP0200332A3 (de)
IL (1)	IL144340A0 (de)
NO (1)	NO20013731L (de)
NZ (1)	NZ512884A (de)
PT (1)	PT1147112E (de)
SK (1)	SK10692001A3 (de)
TR (1)	TR200102162T2 (de)
TW (1)	TW200300021A (de)
WO (1)	WO2000044755A1 (de)
ZA (1)	ZA200105835B (de)

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2000
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- 2000-01-25 CN CN00805544A patent/CN1345320A/zh active Pending
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Publication number	Publication date
HUP0200332A3 (en)	2002-09-30
SK10692001A3 (sk)	2002-01-07
KR20010101725A (ko)	2001-11-14
ZA200105835B (en)	2002-10-16
HUP0200332A2 (en)	2002-06-29
ES2209825T3 (es)	2004-07-01
AU2856900A (en)	2000-08-18
DE60006213D1 (de)	2003-12-04
JP4676062B2 (ja)	2011-04-27
TW200300021A (en)	2003-05-01
PT1147112E (pt)	2004-03-31
CZ20012716A3 (cs)	2001-11-14
ATE253067T1 (de)	2003-11-15
WO2000044755A1 (en)	2000-08-03
CA2361525A1 (en)	2000-08-03
EP1359152A2 (de)	2003-11-05
CO5150231A1 (es)	2002-04-29
EP1359152B1 (de)	2008-05-07
AU773795B2 (en)	2004-06-03
IL144340A0 (en)	2002-05-23
BG105836A (en)	2002-03-29
DK1147112T3 (da)	2004-02-23
NZ512884A (en)	2004-03-26
BR0007664A (pt)	2002-05-07
EP1147112A1 (de)	2001-10-24
CA2361525C (en)	2009-12-08
JP2002535409A (ja)	2002-10-22
HK1043116A1 (en)	2002-09-06
CN1636996A (zh)	2005-07-13
NO20013731D0 (no)	2001-07-30
AR034538A1 (es)	2004-03-03
DE60006213T2 (de)	2004-07-29
EP1359152A3 (de)	2003-12-17
CN1345320A (zh)	2002-04-17
TR200102162T2 (tr)	2001-12-21
ES2305373T3 (es)	2008-11-01
DE60038823D1 (de)	2008-06-19
HK1043116B (en)	2004-10-15
NO20013731L (no)	2001-09-18
EP1147112B1 (de)	2003-10-29

Publication	Publication Date	Title
ATE394401T1 (de)	2008-05-15	Diazabicycloderivate als nikotin-acetylcholin- rezeptorliganden
DK1218382T3 (da)	2004-03-22	Bicykliske imidazo-3-ylaminderivater
MA25403A1 (fr)	2002-04-01	Ligandes de recepteur de melanocortine
EE200100393A (et)	2002-10-15	Vähivastaste vahenditena kasulikud asendatud bitsüklilised derivaadid
DE60030764D1 (de)	2006-10-26	Biphenyl - sulfonamide als duale angiotensin - endothelin - rezeptor - antagonisten
ATE398120T1 (de)	2008-07-15	Neue quinazolin-derivate
ATE349440T1 (de)	2007-01-15	Als antikrebsmittel verwendbare heterocyklische derivate
DE60021262D1 (de)	2005-08-18	Bizyklische heteroaromatische verbindungen als lh-agonisten
NO20000885L (no)	2000-08-25	4-Fenyl-pyridin-derivater
PT1198453E (pt)	2003-08-29	Derivados de n-(indolcarbonil)-piperazina como ligandos do receptor 5-ht2a
ATE263748T1 (de)	2004-04-15	Admantan-derivate
DE50015443D1 (de)	2008-12-18	Bicyclische imidazo-5-yl-aminderivate
DK1202953T3 (da)	2006-12-27	Substituerede 2-dialkylaminoalkylbiphenylderivater
ATE257148T1 (de)	2004-01-15	Propargyletherderivate
NO20013997D0 (no)	2001-08-16	Reseptoranalyse
DK1154988T3 (da)	2004-11-22	Mevinolinderivater
ATE374747T1 (de)	2007-10-15	Monofluoralkylderivate
DK1187815T3 (da)	2006-06-19	4-phenyl-pyrimidinderivater
DE60006703D1 (de)	2003-12-24	4-hydroxybiphenylhydrazid-derivate
ATE293592T1 (de)	2005-05-15	Resorcinderivate
DE60003072D1 (de)	2003-07-03	Thiazolidindion-derivate als antidiabetika
ATE281456T1 (de)	2004-11-15	Aminotriazolopyridinderivate als adenosinrezeptorliganden
DE60012953D1 (de)	2004-09-16	3-amino-2-phenylpiperidinderivate als substanz p antagonisten
NO20021295L (no)	2002-05-14	Nikotinsyreacetylcholin-reseptor
DE60015819D1 (de)	2004-12-16	Pyrazolopyridinon als Zwischenprodukt

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