ATA189395A - Orale pharmazeutische zubereitung - Google Patents

Orale pharmazeutische zubereitung

Info

Publication number: ATA189395A
Authority: AT; Austria
Prior art keywords: weight; pharmaceutical preparation; oral pharmaceutical; ethanol; solvent
Prior art date: 1994-11-21

Application number

AT0189395A

Other languages

English (en)

Other versions

AT408945B (de

Inventor

Istvan Kovacs

Marta Jusztin

Erzsebet Takacs

Marta Jarabin

Zoltan Balazs

Ildiko Kiss

Zsolt Varga

Sandor Jancso

Csaba Heim

Korcsmaros Ildiko Kanya

Erzsebet Erdoehati

Original Assignee

Biogal Gyoegyszergyar Rt

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-21

Filing date

1995-11-21

Publication date

2001-09-15

1995-11-21 Application filed by Biogal Gyoegyszergyar Rt filed Critical Biogal Gyoegyszergyar Rt

2001-09-15 Publication of ATA189395A publication Critical patent/ATA189395A/de

2002-04-25 Application granted granted Critical

2002-04-25 Publication of AT408945B publication Critical patent/AT408945B/de

Links

239000008183 oral pharmaceutical preparation Substances 0.000 title 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 4
239000002904 solvent Substances 0.000 abstract 3
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
229930105110 Cyclosporin A Natural products 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
239000002202 Polyethylene glycol Substances 0.000 abstract 1
ZAKOWWREFLAJOT-ADUHFSDSSA-N [2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate Chemical group CC(=O)OC1=C(C)C(C)=C2OC(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-ADUHFSDSSA-N 0.000 abstract 1
150000001733 carboxylic acid esters Chemical class 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
239000012141 concentrate Substances 0.000 abstract 1
229930182912 cyclosporin Natural products 0.000 abstract 1
239000000839 emulsion Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229920001223 polyethylene glycol Polymers 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Dispersion Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Oil, Petroleum & Natural Gas (AREA)
Oncology (AREA)
Tropical Medicine & Parasitology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Communicable Diseases (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AT0189395A 1994-11-21 1995-11-21 Orale pharmazeutische zubereitung AT408945B (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU9403328A HU215966B (hu)	1994-11-21	1994-11-21	Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum

Publications (2)

Publication Number	Publication Date
ATA189395A true ATA189395A (de)	2001-09-15
AT408945B AT408945B (de)	2002-04-25

Family

ID=10985774

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT95106655T ATE245994T1 (de)	1994-11-21	1995-05-03	Cyclosporin enthaltende multiple emulsionen
AT0189395A AT408945B (de)	1994-11-21	1995-11-21	Orale pharmazeutische zubereitung

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT95106655T ATE245994T1 (de)	1994-11-21	1995-05-03	Cyclosporin enthaltende multiple emulsionen

Country Status (16)

Country	Link
US (1)	US5583105A (de)
EP (1)	EP0712631B1 (de)
KR (1)	KR100377058B1 (de)
AT (2)	ATE245994T1 (de)
CA (1)	CA2145242C (de)
CZ (1)	CZ286686B6 (de)
DE (2)	DE69531389T2 (de)
DK (1)	DK0712631T3 (de)
ES (1)	ES2202330T3 (de)
GB (1)	GB2295546B (de)
HU (1)	HU215966B (de)
IT (1)	IT1281337B1 (de)
PL (1)	PL182716B1 (de)
PT (1)	PT712631E (de)
SI (1)	SI9500350B (de)
SK (1)	SK283045B6 (de)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19521974A1 (de) *	1995-06-16	1996-12-19	Hexal Pharmaforschung Gmbh	Pharmazeutische Zubereitung mit Cyclosporin A
US6696413B2 (en) *	1995-06-16	2004-02-24	Hexal Ag	Pharmaceutical preparation with cyclosporin A
GB2317562B (en) *	1995-07-20	1999-08-18	Danbiosyst Uk	Lipid vehicle drug delivery composition containing vitamin E
US5766629A (en)	1995-08-25	1998-06-16	Sangstat Medical Corporation	Oral cyclosporin formulations
US5962019A (en) *	1995-08-25	1999-10-05	Sangstat Medical Corporation	Oral cyclosporin formulations
US5827822A (en) *	1996-03-25	1998-10-27	Sangstat Medical Corporation	Cyclosporin a formulations as nanoparticles
NZ280689A (en) *	1995-12-15	1997-08-22	Bernard Charles Sherma Sherman	Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol
US5858401A (en)	1996-01-22	1999-01-12	Sidmak Laboratories, Inc.	Pharmaceutical composition for cyclosporines
CZ292378B6 (cs) *	1996-06-19	2003-09-17	Novartis Ag	Přípravek obsahující cyklosporin a způsob jeho přípravy
KR19980073479A (ko) *	1997-03-14	1998-11-05	한스루돌프하우스, 니콜케르커	사이클로스포린-함유 연질캅셀제
KR0183449B1 (ko) *	1996-06-19	1999-05-01	한스 루돌프 하우스, 니콜 케르커	사이클로스포린-함유 연질캅셀제
US5958876A (en) *	1996-06-19	1999-09-28	Novartis Ag	Cyclosporin-containing pharmaceutical compositions
JP2001523221A (ja) *	1996-09-01	2001-11-20	ファーモスコーポレイション	親油性物質の促進された生物学的利用能のための固形共沈物
US5891469A (en) *	1997-04-02	1999-04-06	Pharmos Corporation	Solid Coprecipitates for enhanced bioavailability of lipophilic substances
US5798333A (en) *	1996-09-17	1998-08-25	Sherman; Bernard C.	Water-soluble concentrates containing cyclosporins
US6458373B1 (en) *	1997-01-07	2002-10-01	Sonus Pharmaceuticals, Inc.	Emulsion vehicle for poorly soluble drugs
GB2326337A (en)	1997-06-20	1998-12-23	Phares Pharma Holland	Homogeneous lipid compositions for drug delivery
US20030220234A1 (en)	1998-11-02	2003-11-27	Selvaraj Naicker	Deuterated cyclosporine analogs and their use as immunodulating agents
US5891845A (en) *	1997-11-21	1999-04-06	Fuisz Technologies Ltd.	Drug delivery systems utilizing liquid crystal structures
US6028067A (en) *	1997-12-05	2000-02-22	Chong Kun Dang Corp.	Cyclosporin-containing microemulsion preconcentrate composition
US6063762A (en) *	1997-12-05	2000-05-16	Chong Kun Dang Corp.	Cyclosporin-containing microemulsion preconcentrate composition
WO1999029335A1 (en) *	1997-12-05	1999-06-17	Chong Kun Dang Corp.	Pharmaceutical composition containing cyclosporin
JP4761093B2 (ja) *	1997-12-10	2011-08-31	シクロスポリンセラポイティクスリミテッド	オメガ−３脂肪酸油を含む医薬組成物
ID25908A (id) *	1998-03-06	2000-11-09	Novartis Ag	Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida
US20030216303A1 (en) *	1998-03-06	2003-11-20	Michael Ambuhl	Emulsion preconcentrates containing cyclosporin or a macrolide
US7030155B2 (en) *	1998-06-05	2006-04-18	Sonus Pharmaceuticals, Inc.	Emulsion vehicle for poorly soluble drugs
NZ512599A (en)	1998-12-30	2003-10-31	Dexcel Ltd	Formulation for cyclosporin administration featuring a hydrophilic solvent and a surfactant with a HLB of less than 5
US6045826A (en)	1999-04-02	2000-04-04	National Research Council Of Canada	Water-soluble compositions of bioactive lipophilic compounds
US6632443B2 (en)	2000-02-23	2003-10-14	National Research Council Of Canada	Water-soluble compositions of bioactive lipophilic compounds
US20080070981A1 (en)	2000-02-23	2008-03-20	Henryk Borowy-Borowski	Water-soluble compositions of bioactive lipophilic compounds
GB9912476D0 (en)	1999-05-28	1999-07-28	Novartis Ag	Organic compounds
DE19925001A1 (de) *	1999-05-31	2000-12-07	Pharma Concepts Gmbh & Co Kg	Flüssiges Konzentrat
CA2385989A1 (en) *	1999-09-27	2001-04-05	Andrew Nienstedt	Compositions of tocol-soluble therapeutics
CA2392353A1 (en) *	1999-11-22	2001-05-31	Galephar Pharmaceutical Research, Inc.	Stable acid labile benzimidazole pharmaceutical compositions
US7732404B2 (en)	1999-12-30	2010-06-08	Dexcel Ltd	Pro-nanodispersion for the delivery of cyclosporin
US7919113B2 (en) *	1999-12-30	2011-04-05	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Dispersible concentrate lipospheres for delivery of active agents
US20050037073A1 (en) *	2000-01-13	2005-02-17	Alpharx Inc.	Solid self-emulsifying dosage form for improved delivery of poorly soluble hydrophobic compounds and the process for preparation thereof
AUPR549901A0 (en) *	2001-06-06	2001-07-12	Vital Health Sciences Pty Ltd	Topical formulation containing tocopheryl phosphates
US20040097472A1 (en) *	2000-11-14	2004-05-20	West Simon Michael	Complexes of phosphate derivatives
JP4745608B2 (ja) *	2001-07-27	2011-08-10	バイタルヘルスサイエンシズプロプライアタリーリミティド	電子伝達剤のリン酸誘導体を用いた皮膚治療
US6960563B2 (en) *	2001-08-31	2005-11-01	Morton Grove Pharmaceuticals, Inc.	Spontaneous emulsions containing cyclosporine
ES2266564T3 (es)	2001-10-19	2007-03-01	Isotechnika Inc.	Sintesis de analogos de cicloporinas.
MXPA04003623A (es) *	2001-10-19	2004-12-02	Isotechnika Inc	Nuevas formulaciones analogas de ciclosporina.
WO2003049774A1 (en) *	2001-12-13	2003-06-19	Vital Health Sciences Pty Ltd	Transdermal transport of compounds
AU2002950713A0 (en) *	2002-08-09	2002-09-12	Vital Health Sciences Pty Ltd	Carrier
JP4690305B2 (ja) *	2003-01-17	2011-06-01	バイタルヘルスサイエンシズプロプライアタリーリミティド	抗増殖性質を有する化合物
AU2003901815A0 (en) *	2003-04-15	2003-05-01	Vital Health Sciences Pty Ltd	Phosphate derivatives
US20050074469A1 (en) *	2003-10-03	2005-04-07	Charles Signorino	Stable lipophilic emulsions for acrylic coating and method of making
EP1558215A4 (de) *	2003-10-14	2007-09-12	Wockhardt Ltd	Sterile geliermittel
EP1715922A2 (de) *	2004-02-06	2006-11-02	Showa Denko Kabushiki Kaisha	Verfahren zur stabilisierung einer verdickungsgelzusammensetzung auf ölbasis
NZ549567A (en)	2004-03-03	2009-10-30	Vital Health Sciences Pty Ltd	Formulations comprising a tocopheryl phosphate tertiary amine alkaloid complex
US20050277584A1 (en) *	2004-06-09	2005-12-15	Allergan, Inc.	Pharmaceutical compositions comprising cyclosporins
US20060088591A1 (en) *	2004-10-22	2006-04-27	Jinghua Yuan	Tablets from a poorly compressible substance
JP2008518931A (ja) *	2004-10-29	2008-06-05	ノバルティスアクチエンゲゼルシャフト	自発的に分散可能な医薬組成物
ES2557475T3 (es) *	2005-06-17	2016-01-26	Vital Health Sciences Pty Ltd.	Un portador que comprende uno o más derivados di- y/o monofosfato de agentes de transferencia de electrones
US20070087962A1 (en) *	2005-10-17	2007-04-19	Allergan, Inc.	Pharmaceutical compositions comprising cyclosporins
WO2007070981A1 (en) *	2005-12-23	2007-06-28	Vital Health Sciences Pty Ltd	Compounds having cytokine modulating properties
EP1867323A1 (de) *	2006-06-13	2007-12-19	Farmatron Ltd.	Pharmazeutische Zusammensetzungen mit verbesserter Permeation durch biologische Barrieren
DK2548456T3 (en)	2008-03-20	2015-09-28	Virun Inc	Emulsions including (comprising) a PEG derivative of tocopherol
BRPI0909185A2 (pt)	2008-03-20	2015-08-25	Virun Inc	Derivado de vitamina e e seus usos
ES2344674B1 (es) *	2008-08-07	2011-06-29	Gp Pharm, S.A.	Composicion farmaceutica inyectable de taxanos.
US10071030B2 (en)	2010-02-05	2018-09-11	Phosphagenics Limited	Carrier comprising non-neutralised tocopheryl phosphate
KR101622441B1 (ko)	2010-03-23	2016-05-18	버런, 아이엔씨.	자당 지방산 에스테르를 포함하는 나노에멀전
ES2829386T3 (es)	2010-03-30	2021-05-31	Phosphagenics Ltd	Parche de administración transdérmica
US8741373B2 (en)	2010-06-21	2014-06-03	Virun, Inc.	Compositions containing non-polar compounds
AU2011300428B2 (en)	2010-09-07	2016-03-24	Dsm Nutritional Products Ag	Comestible emulsions
EP2685992A4 (de)	2011-03-15	2014-09-10	Phosphagenics Ltd	Aminochinoline als kinasehemmer
WO2013090842A2 (en) *	2011-12-16	2013-06-20	Allergan, Inc.	Ophthalmic compositions comprising polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymers
US10874122B2 (en)	2012-02-10	2020-12-29	Virun, Inc.	Beverage compositions containing non-polar compounds
ITRM20120331A1 (it)	2012-07-12	2014-01-13	Guidotti & C Spa Labor	Composizioni pediatriche orali liquide contenenti nepadutant.
GB201222455D0 (en) *	2012-12-13	2013-01-30	Perioc Ltd	Novel pharmaceutical formulations and their use in the treatment of periodontaldisease
US9351517B2 (en)	2013-03-15	2016-05-31	Virun, Inc.	Formulations of water-soluble derivatives of vitamin E and compositions containing same
US9693574B2 (en)	2013-08-08	2017-07-04	Virun, Inc.	Compositions containing water-soluble derivatives of vitamin E mixtures and modified food starch
US9861611B2 (en)	2014-09-18	2018-01-09	Virun, Inc.	Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same
US10016363B2 (en)	2014-09-18	2018-07-10	Virun, Inc.	Pre-spray emulsions and powders containing non-polar compounds
ES2981002T3 (es)	2015-12-09	2024-10-04	Avecho Biotechnology Ltd	Formulación farmacéutica
JP7198754B2 (ja)	2016-12-21	2023-01-04	アベーチョバイオテクノロジーリミテッド	方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE295765C (de) *
DE298351C (de) *	1915-04-09
FI65914C (fi) *	1978-03-07	1984-08-10	Sandoz Ag	Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
US4861580A (en) *	1985-10-15	1989-08-29	The Liposome Company, Inc.	Composition using salt form of organic acid derivative of alpha-tocopheral
US5154930A (en) *	1987-03-05	1992-10-13	The Liposome Company, Inc.	Pharmacological agent-lipid solution preparation
US5342625A (en) *	1988-09-16	1994-08-30	Sandoz Ltd.	Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) *	1988-09-16	1998-08-17	장 크라메르, 한스 루돌프 하우스	사이클로스포린을 함유하는 약학조성물
DE3908047A1 (de) *	1989-03-13	1990-09-20	Desitin Arzneimittel Gmbh	Hochdisperse pharmazeutische zusammensetzung
CA2013755C (en) *	1989-04-05	1993-11-30	Simon Benita	Medicinal emulsions
US5364632A (en) *	1989-04-05	1994-11-15	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Medicinal emulsions
US5234695A (en) *	1990-07-24	1993-08-10	Eastman Kodak Company	Water dispersible vitamin E composition
HU208491B (en) *	1990-11-27	1993-11-29	Gyogyszerkutato Intezet	Process for producing oral pharmaceutical composition containing cyclosporin
GB9113872D0 (en) *	1991-06-27	1991-08-14	Sandoz Ag	Improvements in or relating to organic compounds
IL101241A (en) *	1992-03-16	1997-11-20	Yissum Res Dev Co	Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
GB9208712D0 (en) *	1992-04-22	1992-06-10	Sandoz Ltd	Pharmaceutical compositions containing cyclosporin derivates
US5527537A (en) *	1992-05-18	1996-06-18	Dietl; Hans	Pharmaceutical preparation containing cyclosporine(s) for intravenous administration and a process for its production
ES2168271T3 (es) *	1992-09-25	2002-06-16	Novartis Ag	Composiciones farmaceuticas que contienen ciclosporinas.
JPH08502492A (ja) *	1992-10-16	1996-03-19	スミスクライン・ビーチャム・コーポレイション	治療用ミクロエマルジョン
JPH08502490A (ja) *	1992-10-16	1996-03-19	スミスクライン・ビーチャム・コーポレイション	組成物
EP0724452B1 (de) *	1993-10-22	2000-05-24	Hexal Ag	Pharmazeutische zusammensetzung mit cyclosporin a, einen vitamin e derivat und einen emulgator
US5447729A (en) *	1994-04-07	1995-09-05	Pharmavene, Inc.	Multilamellar drug delivery systems

1994
- 1994-11-21 HU HU9403328A patent/HU215966B/hu not_active IP Right Cessation
1995
- 1995-03-21 CA CA002145242A patent/CA2145242C/en not_active Expired - Fee Related
- 1995-03-31 US US08/414,496 patent/US5583105A/en not_active Expired - Lifetime
- 1995-04-25 CZ CZ19951054A patent/CZ286686B6/cs not_active IP Right Cessation
- 1995-04-27 SK SK544-95A patent/SK283045B6/sk not_active IP Right Cessation
- 1995-05-03 AT AT95106655T patent/ATE245994T1/de not_active IP Right Cessation
- 1995-05-03 PT PT95106655T patent/PT712631E/pt unknown
- 1995-05-03 ES ES95106655T patent/ES2202330T3/es not_active Expired - Lifetime
- 1995-05-03 DE DE69531389T patent/DE69531389T2/de not_active Expired - Fee Related
- 1995-05-03 DK DK95106655T patent/DK0712631T3/da active
- 1995-05-03 EP EP95106655A patent/EP0712631B1/de not_active Expired - Lifetime
- 1995-05-08 KR KR1019950011130A patent/KR100377058B1/ko not_active Expired - Fee Related
- 1995-11-13 SI SI9500350A patent/SI9500350B/sl not_active IP Right Cessation
- 1995-11-14 GB GB9523295A patent/GB2295546B/en not_active Expired - Fee Related
- 1995-11-20 DE DE19543271A patent/DE19543271B4/de not_active Expired - Fee Related
- 1995-11-20 PL PL95311430A patent/PL182716B1/pl not_active IP Right Cessation
- 1995-11-21 AT AT0189395A patent/AT408945B/de not_active IP Right Cessation
- 1995-11-21 IT IT95MI002411A patent/IT1281337B1/it active IP Right Grant

Also Published As

Publication number	Publication date
HK1016814A1 (en)	1999-11-05
HU215966B (hu)	1999-07-28
HU9403328D0 (en)	1995-02-28
DE19543271A1 (de)	1996-06-05
DE69531389T2 (de)	2004-04-15
ITMI952411A1 (it)	1997-05-21
GB2295546A (en)	1996-06-05
EP0712631A2 (de)	1996-05-22
ES2202330T3 (es)	2004-04-01
DE69531389D1 (de)	2003-09-04
SI9500350B (sl)	2005-02-28
GB2295546B (en)	1998-07-22
GB9523295D0 (en)	1996-01-17
KR100377058B1 (ko)	2003-06-11
CZ286686B6 (en)	2000-06-14
EP0712631B1 (de)	2003-07-30
CZ105495A3 (en)	1996-07-17
DE19543271B4 (de)	2006-05-24
CA2145242A1 (en)	1996-05-22
PT712631E (pt)	2003-11-28
SK54495A3 (en)	1997-02-05
KR960016903A (ko)	1996-06-17
CA2145242C (en)	2001-08-07
US5583105A (en)	1996-12-10
DK0712631T3 (da)	2003-10-27
SK283045B6 (sk)	2003-02-04
PL311430A1 (en)	1996-05-27
ATE245994T1 (de)	2003-08-15
EP0712631A3 (de)	1996-12-04
IT1281337B1 (it)	1998-02-18
ITMI952411A0 (de)	1995-11-21
SI9500350A (en)	1996-06-30
AT408945B (de)	2002-04-25
PL182716B1 (pl)	2002-02-28

Publication	Publication Date	Title
ATA189395A (de)	2001-09-15	Orale pharmazeutische zubereitung
NO20000466L (no)	2000-03-28	Farmasøytisk preparat for sure, lipofile forbindelser i form av en selvregulerende formulering
ATE152613T1 (de)	1997-05-15	Zusammensetzung, die bei peroraler verabreichung eine mikroemulsion bildet
MA26507A1 (fr)	2004-12-20	Compositions pharmaceutiques d'aerosol
ATE275963T1 (de)	2004-10-15	Ölfreie pharmazeutische zusammensetzung welche cyclosporin enthält
ATE554750T1 (de)	2012-05-15	Hydrophobe pharmazeutische wirkstoffe enthaltende zubereitungen
ATE236628T1 (de)	2003-04-15	Fenofibrathaltige neue galenische arzneizusammensetzungen und ihre verwendung
ITRM920361A1 (it)	1993-11-12	Composizioni farmaceutiche contenenti un composto allilamminico quale principio attivo.
ES2191979T3 (es)	2003-09-16	Sistema de administracion de acido linoleico conjugado en preparaciones cosmeticas.
PT910353E (pt)	2004-11-30	Administracao transdermica de farmacos basicos utilizando sistemas adesivos naopolares e agentes de solubilizacao acidos
MX9203496A (es)	1992-08-01	Derivados de difenilheteroalquilos, la preparacion de los mismos y drogas y cosmeticos preparados a partir de los mismos.
KR950010875A (ko)	1995-05-15	피부외용제
BR0009765B1 (pt)	2013-11-05	Compostos de ésteres de l-carnitina ou alcanoil l-carnitinase, uso dos mesmos, lipossomas contendo os referidos compostos e composições farmacêuticas e cosméticas contendo os ditos lipossomas.
CA2148112A1 (en)	1995-10-30	New pharmaeutical dosage form for transdermal administration
NL300055I2 (nl)	2002-04-02	Rapamycinepreparaten voor orale toediening.
ATE127683T1 (de)	1995-09-15	Stabile emulgierte tretinoin-cremeformulierungen.
ES2192241T3 (es)	2003-10-01	Composiciones estables de proteccion a la luz que contienen derivados tensioactivos de glucosa y filtros uv solubles en agua.
ATE135913T1 (de)	1996-04-15	Topisch anzuwendende niclosamid enthaltende lotion
ATE181324T1 (de)	1999-07-15	Im kardiovaskulären system aktive seco-d-steroide und diese enthaltende pharmazeutische zubereitungen
KR890701098A (ko)	1989-12-19	히드로퀴논 및 코지산을 함유하는 제약 또는 화장제 조성물
JPS5750914A (en)	1982-03-25	Betamethasone external pharmaceutical
ES2180065T3 (es)	2003-02-01	Formulaciones de uso topico que contienen acetato de vitamina e.
DE59408420D1 (de)	1999-07-22	Niedrigviskose kosmetische und pharmazeutische emulsionen
NO923266L (no)	1993-02-22	Heksahydrobenzo(f)quinolinoner
ITMI913510A0 (it)	1991-12-31	Composizioni farmaceutiche contenenti progesterone ad elevata biodisponibilita'

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2006-11-15	EFA	Change in the company name
2011-05-15	ELJ	Ceased due to non-payment of the annual fee