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AR116302A1 - Pirazoles fungicidas sustituidos con nitroanilino - Google Patents

Pirazoles fungicidas sustituidos con nitroanilino

Info

Publication number
AR116302A1
AR116302A1 ARP190102553A ARP190102553A AR116302A1 AR 116302 A1 AR116302 A1 AR 116302A1 AR P190102553 A ARP190102553 A AR P190102553A AR P190102553 A ARP190102553 A AR P190102553A AR 116302 A1 AR116302 A1 AR 116302A1
Authority
AR
Argentina
Prior art keywords
amine
nitrophenyl
pyrazol
dimethyl
difluoro
Prior art date
Application number
ARP190102553A
Other languages
English (en)
Inventor
Srinivas Chittaboina
Travis Chandler Mmahon
Jeffrey Keith Long
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Publication of AR116302A1 publication Critical patent/AR116302A1/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/227Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • C07C49/233Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/40Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by doubly-bound oxygen atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/12Powders or granules
    • A01N25/14Powders or granules wettable
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/30Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01PBIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P3/00Fungicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/29Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Toxicology (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Catching Or Destruction (AREA)

Abstract

Se describen compuestos de la fórmula (1), que incluyen todos los isómeros geométricos y estereoisómeros, tautómeros, N-óxidos y sales de estos, en donde R¹, R², R³, R⁴, R⁵, R⁶, m y n son como se definen en la descripción. También se describen composiciones que contienen los compuestos de la fórmula (1) y métodos para controlar enfermedades de las plantas causadas por un patógeno fúngico que comprende aplicar una cantidad eficaz de un compuesto o una composición de la presente. Reivindicación 1: Un compuesto seleccionado de la fórmula (1), tautómeros, N-óxidos, y sales de este, en donde R¹ es alquilo C₁₋₂; R² es ciano, halógeno, alquilo C₁₋₂ o haloalquilo C₁₋₂; R³ es halógeno o metilo; cada R⁴ es independientemente halógeno, ciano, nitro, alquilo C₁₋₃, alcoxi C₁₋₃, haloalcoxi C₁₋₃, alqueniloxi C₂₋₆, alquiniloxi C₂₋₆, cianoalcoxi C₂₋₆, alcoxialquilo C₂₋₆ o alcoxialcoxi C₂₋₆; cada R⁵ es independientemente halógeno, alquilo C₁₋₃, alcoxialquilo C₂₋₆, alcoxi C₁₋₃, haloalcoxi C₁₋₃, alqueniloxi C₂₋₆, alquiniloxi C₂₋₆, cianoalcoxi C₂₋₆ o alcoxialcoxi C₂₋₆; m y n son independientemente 0, 1, 2 ó 3; R⁶ es H; o alquilo C₁₋₃ o haloalquilo C₁₋₃, cada uno opcionalmente sustituido con hasta 2 sustituyentes seleccionados independientemente de R⁶ᵃ; o amino, alquenilo C₂₋₄, alquinilo C₂₋₄, cicloalquilo C₃₋₆, CH(=O), S(=O)₂OM, S(=O)ᵘR⁷, (C=W)R⁸ u OR⁹; cada R⁶ᵃ es independientemente ciano, cicloalquilo C₃₋₆, alcoxi C₁₋₃, haloalcoxi C₁₋₃, alquiltio C₁₋₃, alquilsulfinilo C₁₋₃ o alquilsulfonilo C₁₋₃; M es K o Na; u es 0, 1 ó 2; R⁷ es alquilo C₁₋₃ o haloalquilo C₁₋₃; W es O ó S; R⁸ es alquilo C₁₋₃, alcoxialquilo C₂₋₄, alquilaminoalquilo C₂₋₄, dialquilaminoalquilo C₃₋₆, alcoxi C₁₋₃, alquiltio C₁₋₃ o alquiltioalquilo C₂₋₄; R⁹ es H; o alquilo C₁₋₃ o haloalquilo C₁₋₃, cada uno opcionalmente sustituido con hasta 2 sustituyentes seleccionados independientemente de R⁹ᵃ; o CH(=O), cicloalquilo C₃₋₆, S(=O)₂OM o (C=W)R¹⁰; cada R⁹ᵃ es independientemente ciano, cicloalquilo C₃₋₆, alcoxi C₁₋₃, haloalcoxi C₁₋₃, alquiltio C₁₋₃, alquilsulfinilo C₁₋₃ o alquilsulfonilo C₁₋₃; y R¹⁰ es alquilo C₁₋₃, alcoxialquilo C₂₋₄, alquilaminoalquilo C₂₋₄, dialquilaminoalquilo C₃₋₆, alcoxi C₁₋₃, alquiltio C₁₋₃ o alquiltioalquilo C₂₋₄; siempre que el compuesto de fórmula (1) no sea: 4-(2,6-difluoro-4-metoxifenil)-N-(2,4-difluoro-6-nitrofenil)-1,3-dimetil-1H-pirazol-5-amina; 4-(2-cloro-4-fluorofenil)-1,3-dimetil-N-(2-nitrofenil)-1H-pirazol-5-amina; 4-(2-cloro-4-fluorofenil)-N-(2,4-difluoro-6-nitrofenil)-1,3-dimetil-1H-pirazol-5-amina; 4-(2-cloro-4-fluorofenil)-3-etil-1-metil-N-(2-nitrofenil)-1H-pirazol-5-amina; 4-(2-cloro-4-fluorofenil)-1-metil-N-(2-nitrofenil)-3-(trifluorometil)-1H-pirazol-5-amina; 4-(2,6-difluoro-4-metoxifenil)-N-(2-metoxi-6-nitrofenil)-1,3-dimetil-1H-pirazol-5-amina; 4-(2-cloro-4-fluorofenil)-N-(2-metoxi-6-nitrofenil)-1,3-dimetil-1H-pirazol-5-amina; N-(2-cloro-6-nitrofenil)-4-(2,6-difluoro-4-metoxifenil)-1,3-dimetil-1H-pirazol-5-amina; N-(2-cloro-3-fluoro-6-nitrofenil)-4-(2,6-difluoro-4-metoxifenil)-1,3-dimetil-1H-pirazol-5-amina; 4-(2-cloro-4-fluorofenil)-1,3-dimetil-N-(2-metil-6-nitrofenil)-1H-pirazol-5-amina; N-(2-bromo-4-fluoro-6-nitrofenil)-4-(2-cloro-4-fluorofenil)-1,3-dimetil-1H-pirazol-5-amina; 4-(2-cloro-4-fluorofenil)-N-(4-metoxi-2-nitrofenil)-1,3-dimetil-1H-pirazol-5-amina; 4-(2,6-difluoro-4-metoxifenil)-N-(4-fluoro-2-nitrofenil)-1,3-dimetil-1H-pirazol-5-amina; 4-(2,6-difluoro-4-metoxifenil)-N-(4-metoxi-2-nitrofenil)-1,3-dimetil-1H-pirazol-5-amina; N-(4-cloro-2-nitrofenil)-4-(2,6-difluoro-4-metoxifenil)-1,3-dimetil-1H-pirazol-5-amina; 4-(2,6-difluoro-4-metoxifenil)-1,3-dimetil-N-[2-nitro-4-(2-propin-1-iloxi)fenil]-1H-pirazol-5-amina; 4-(2,6-difluoro-4-metoxifenil)-1,3-dimetil-N-[2-nitro-4-(2-propen-1-iloxi)fenil]-1H-pirazol-5-amina; N-(4-bromo-2-nitrofenil)-4-(2,6-difluoro-4-metoxifenil)-1,3-dimetil-1H-pirazol-5-amina; N-(4-cloro-2-fluoro-6-nitrofenilo)-4-(2,6-difluoro-4-metoxifenil)-1,3-dimetil-1H-pirazol-5-amina; 3-cloro-4-(2-cloro-4-fluorofenil)-N-(2,4-difluoro-6-nitrofenil)-1-metil-1H-pirazol-5-amina; 4-(2,6-difluoro-4-metoxifenil)-1,3-dimetil-N-(4-metil-2-nitrofenil)-1H-pirazol-5-amina; 4-(2-cloro-4-fluorofenil)-1,3-dimetil-N-(4-metil-2-nitrofenil)-1H-pirazol-5-amina; y N-(4-bromo-2-fluoro-6-nitrofenil)-4-(2,6-difluoro-4-metoxifenil)-1,3-dimetil-1H-pirazol-5-amina.
ARP190102553A 2018-09-06 2019-09-06 Pirazoles fungicidas sustituidos con nitroanilino AR116302A1 (es)

Applications Claiming Priority (1)

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US201862727727P 2018-09-06 2018-09-06

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AR116302A1 true AR116302A1 (es) 2021-04-21

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US (1) US12398107B2 (es)
EP (2) EP4388876A3 (es)
JP (2) JP7440495B2 (es)
KR (2) KR102869748B1 (es)
CN (2) CN118684570A (es)
AR (1) AR116302A1 (es)
AU (1) AU2019336763B2 (es)
CA (1) CA3114291A1 (es)
CL (1) CL2021000538A1 (es)
CO (1) CO2021002940A2 (es)
DK (1) DK3847160T3 (es)
EC (1) ECSP21015020A (es)
ES (1) ES2984583T3 (es)
FI (1) FI3847160T3 (es)
HR (1) HRP20241011T1 (es)
HU (1) HUE067489T2 (es)
IL (1) IL281110B2 (es)
LT (1) LT3847160T (es)
MA (1) MA53549B1 (es)
MX (2) MX2021002460A (es)
MY (1) MY204984A (es)
PE (1) PE20210672A1 (es)
PH (1) PH12021550390A1 (es)
PL (1) PL3847160T4 (es)
RS (1) RS65783B1 (es)
SG (1) SG11202101809YA (es)
SI (1) SI3847160T1 (es)
TW (2) TW202400547A (es)
UA (1) UA128019C2 (es)
UY (1) UY38362A (es)
WO (1) WO2020051402A1 (es)
ZA (1) ZA202101373B (es)

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UY39189A (es) 2020-05-06 2021-12-31 Fmc Corp Fungicidas de tolilo sustituido y sus mezclas
AR124367A1 (es) 2020-12-17 2023-03-22 Fmc Corp Oxadiazoles fungicidas y sus mezclas
TW202420997A (zh) 2022-11-18 2024-06-01 美商富曼西公司 琥珀酸去氫酶抑制劑和吡啶醯胺的混合物

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