AR075927A1 - Procedimiento para la produccion de glioxilato mediante fermentacion - Google Patents
Procedimiento para la produccion de glioxilato mediante fermentacionInfo
- Publication number
- AR075927A1 AR075927A1 ARP100100930A ARP100100930A AR075927A1 AR 075927 A1 AR075927 A1 AR 075927A1 AR P100100930 A ARP100100930 A AR P100100930A AR P100100930 A ARP100100930 A AR P100100930A AR 075927 A1 AR075927 A1 AR 075927A1
- Authority
- AR
- Argentina
- Prior art keywords
- procedure
- production
- glioxylate
- fermentation
- recombinant microorganism
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000000855 fermentation Methods 0.000 title 1
- 230000004151 fermentation Effects 0.000 title 1
- 244000005700 microbiome Species 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 241000588722 Escherichia Species 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000012239 gene modification Methods 0.000 abstract 1
- 230000005017 genetic modification Effects 0.000 abstract 1
- 235000013617 genetically modified food Nutrition 0.000 abstract 1
- HHLFWLYXYJOTON-UHFFFAOYSA-N glyoxylic acid Chemical compound OC(=O)C=O HHLFWLYXYJOTON-UHFFFAOYSA-N 0.000 abstract 1
- 238000004448 titration Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/848—Escherichia
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Procedimiento para la bioconversion de una fuente de carbono fermentable en glioxilato mediante un microorganismo recombinante con modificaciones genéticas como por ejemplo deltaldhA, deltamgsA, deltaarcA y deltalldP, deltaglcA, deltayjcG y la combinacion de ellas que permite una produccion con mayor rendimiento, valoracion y productividad. Se provee además el microorganismo recombinante que pertenece al género Escherichia.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16271209P | 2009-03-24 | 2009-03-24 | |
| EP09155971A EP2233562A1 (en) | 2009-03-24 | 2009-03-24 | Method for producing high amount of glycolic acid by fermentation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR075927A1 true AR075927A1 (es) | 2011-05-04 |
Family
ID=40671604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100100930A AR075927A1 (es) | 2009-03-24 | 2010-03-23 | Procedimiento para la produccion de glioxilato mediante fermentacion |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8945888B2 (es) |
| EP (2) | EP2233562A1 (es) |
| JP (1) | JP5800795B2 (es) |
| KR (1) | KR101764933B1 (es) |
| CN (1) | CN102365357A (es) |
| AR (1) | AR075927A1 (es) |
| BR (1) | BRPI1012693B1 (es) |
| CA (1) | CA2754949C (es) |
| ES (1) | ES2593084T3 (es) |
| MX (1) | MX2011010024A (es) |
| MY (1) | MY164623A (es) |
| WO (1) | WO2010108909A1 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120178136A1 (en) * | 2009-09-25 | 2012-07-12 | Roquette Freres | Fermentation process for producing glycolic acid |
| WO2011083059A1 (en) * | 2010-01-06 | 2011-07-14 | Universiteit Gent | Bacterial mutants and uses thereof in protein production |
| EP2582828B1 (en) | 2010-06-15 | 2015-07-15 | Metabolic Explorer | Use of inducible promoters in the production of glycolic acid |
| CA2808140A1 (en) * | 2010-08-27 | 2012-03-01 | Metabolic Explorer | Improved glycolic acid fermentative production with a modified microorganism |
| FI125136B (en) | 2011-10-04 | 2015-06-15 | Teknologian Tutkimuskeskus Vtt Oy | Eukaryotic cells and a method for preparing glycolic acid |
| US9719119B2 (en) | 2011-12-16 | 2017-08-01 | Universiteit Gent | Mutant microorganisms to synthesize colanic acid, mannosylated and/or fucosylated oligosaccharides |
| EP2970873A4 (en) * | 2013-03-14 | 2017-02-22 | President and Fellows of Harvard College | Methods for selecting microbes from a genetically modified library to detect and optimize the production of metabolites |
| JP2016163540A (ja) * | 2013-07-09 | 2016-09-08 | 味の素株式会社 | 有用物質の製造方法 |
| FR3028529B1 (fr) | 2014-11-19 | 2016-12-30 | Inst Nat De La Rech Agronomique Inra | Procede de production d'au moins un metabolite d'interet par transformation d'un pentose dans un microorganisme |
| FI20155412A7 (fi) * | 2015-05-29 | 2016-11-30 | Teknologian Tutkimuskeskus Vtt Oy | Sokerien suora konversio glykolihapoksi |
| WO2017059236A1 (en) * | 2015-10-02 | 2017-04-06 | Massachusetts Institute Of Technology | Microbial production of renewable glycolate |
| CN106011185B (zh) * | 2016-06-27 | 2019-12-17 | 江南大学 | 一种无基因敲除提高大肠杆菌中乙醇酸产率的方法 |
| BR112019000132A2 (pt) | 2016-07-08 | 2019-04-16 | Metabolic Explorer Sa | método para a produção fermentativa de moléculas de interesse por microrganismos compreendendo genes que codificam sistema de fosfotransferase de açúcar |
| EP3354742A1 (en) * | 2017-01-26 | 2018-08-01 | Metabolic Explorer | Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid |
| CN118956710A (zh) | 2017-09-07 | 2024-11-15 | 多伦多大学管理委员会 | 从乙二醇生产乙醇酸盐以及相关微生物工程改造 |
| US11293039B2 (en) | 2017-10-02 | 2022-04-05 | Metabolic Explorer | Method for producing organic acid salts from fermentation broth |
| EP3914737A1 (en) | 2019-01-24 | 2021-12-01 | Photanol B.V. | A process for the bioproduction of glycolate |
| WO2020163935A1 (en) | 2019-02-15 | 2020-08-20 | Braskem S.A. | Microorganisms and methods for the production of glycolic acid and glycine via reverse glyoxylate shunt |
| WO2020168407A1 (en) * | 2019-02-20 | 2020-08-27 | Braskem S.A. | Microorganisms and methods for the production of oxygenated compounds from hexoses |
| EP3927816A1 (en) * | 2019-02-20 | 2021-12-29 | Braskem S.A. | Degradation pathway for pentose and hexose sugars |
| CN113025506B (zh) * | 2019-12-24 | 2022-12-09 | 中国科学院天津工业生物技术研究所 | 一种生产乙醇的重组丝状真菌及其构建和应用 |
| WO2022133719A1 (en) * | 2020-12-22 | 2022-06-30 | Rhodia Operations | Method for producing glycolic acid |
| KR102558672B1 (ko) * | 2022-05-17 | 2023-07-25 | 주식회사 엑티브온 | 1,3-프로판디올 생산 변이 미생물 및 이를 이용한 1,3-프로판디올의 생산 방법 |
| JP2025534767A (ja) | 2022-10-20 | 2025-10-17 | アンニッキ ゲーエムベーハー | グリコール酸及び乳酸のアルカリ塩を含有する水溶液を生成するための方法 |
| EP4631928A1 (en) | 2024-04-10 | 2025-10-15 | Metabolic Explorer | Method of purification of glycolic acid, composition and use thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000071738A1 (en) | 1999-05-21 | 2000-11-30 | Cargill Dow Llc | Methods and materials for the synthesis of organic products |
| AU2003205041A1 (en) | 2002-07-12 | 2004-01-29 | Ajinomoto Co., Inc. | Method for producing target substance by fermentation |
| WO2004033646A2 (en) * | 2002-10-04 | 2004-04-22 | E.I. Du Pont De Nemours And Company | Process for the biological production of 1,3-propanediol with high yield |
| US7262046B2 (en) | 2004-08-09 | 2007-08-28 | Rice University | Aerobic succinate production in bacteria |
| CN101023178A (zh) * | 2004-09-17 | 2007-08-22 | 莱斯大学 | 高琥珀酸产出细菌 |
| US20070116852A1 (en) | 2005-11-22 | 2007-05-24 | Josef Schnatmann | Cattle feed preparation |
| WO2007140816A1 (en) | 2006-06-09 | 2007-12-13 | Metabolic Explorer | Glycolic acid production by fermentation from renewable resources |
| KR100780324B1 (ko) | 2006-07-28 | 2007-11-29 | 한국과학기술원 | 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법 |
| CN101641446A (zh) | 2007-03-23 | 2010-02-03 | 代谢探索者公司 | 通过进化和理性设计的组合获得的用于产生1,2-丙二醇的新微生物 |
| BRPI0809039A2 (pt) | 2007-03-23 | 2014-09-16 | Metabolic Explorer Sa | Microorganismos metabolicamente projetados úteis para a produção de 1,2-propanodiol |
-
2009
- 2009-03-24 EP EP09155971A patent/EP2233562A1/en not_active Withdrawn
-
2010
- 2010-03-23 JP JP2012501279A patent/JP5800795B2/ja active Active
- 2010-03-23 AR ARP100100930A patent/AR075927A1/es active IP Right Grant
- 2010-03-23 ES ES10709743.8T patent/ES2593084T3/es active Active
- 2010-03-23 WO PCT/EP2010/053758 patent/WO2010108909A1/en not_active Ceased
- 2010-03-23 MX MX2011010024A patent/MX2011010024A/es not_active Application Discontinuation
- 2010-03-23 MY MYPI2011004484A patent/MY164623A/en unknown
- 2010-03-23 CA CA2754949A patent/CA2754949C/en active Active
- 2010-03-23 BR BRPI1012693-7A patent/BRPI1012693B1/pt active IP Right Grant
- 2010-03-23 CN CN2010800137428A patent/CN102365357A/zh active Pending
- 2010-03-23 EP EP10709743.8A patent/EP2411502B1/en active Active
- 2010-03-23 KR KR1020117024849A patent/KR101764933B1/ko active Active
- 2010-03-23 US US13/258,366 patent/US8945888B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP5800795B2 (ja) | 2015-10-28 |
| CA2754949C (en) | 2021-07-06 |
| US8945888B2 (en) | 2015-02-03 |
| CN102365357A (zh) | 2012-02-29 |
| ES2593084T3 (es) | 2016-12-05 |
| KR101764933B1 (ko) | 2017-08-03 |
| KR20120002593A (ko) | 2012-01-06 |
| MY164623A (en) | 2018-01-30 |
| MX2011010024A (es) | 2011-10-10 |
| US20120315682A1 (en) | 2012-12-13 |
| EP2233562A1 (en) | 2010-09-29 |
| CA2754949A1 (en) | 2010-09-30 |
| JP2012521206A (ja) | 2012-09-13 |
| EP2411502B1 (en) | 2016-08-03 |
| WO2010108909A1 (en) | 2010-09-30 |
| EP2411502A1 (en) | 2012-02-01 |
| BRPI1012693A2 (pt) | 2015-09-15 |
| BRPI1012693B1 (pt) | 2019-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |