AR069838A1 - Proceso para la preparacion de derivados de acido 2-amino-5-cianobenzoico - Google Patents
Proceso para la preparacion de derivados de acido 2-amino-5-cianobenzoicoInfo
- Publication number
- AR069838A1 AR069838A1 ARP080105556A ARP080105556A AR069838A1 AR 069838 A1 AR069838 A1 AR 069838A1 AR P080105556 A ARP080105556 A AR P080105556A AR P080105556 A ARP080105556 A AR P080105556A AR 069838 A1 AR069838 A1 AR 069838A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- formula
- compound
- independently
- preparing
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 5
- 239000003153 chemical reaction reagent Substances 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 101100294106 Caenorhabditis elegans nhr-3 gene Proteins 0.000 abstract 2
- 125000006450 cyclopropyl cyclopropyl group Chemical group 0.000 abstract 2
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 2
- 125000006431 methyl cyclopropyl group Chemical group 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000004793 2,2,2-trifluoroethoxy group Chemical group FC(CO*)(F)F 0.000 abstract 1
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 abstract 1
- 150000001879 copper Chemical class 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-M iodide Chemical compound [I-] XMBWDFGMSWQBCA-UHFFFAOYSA-M 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/14—Preparation of carboxylic acid nitriles by reaction of cyanides with halogen-containing compounds with replacement of halogen atoms by cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Reivindicacion 1: Un método para preparar un compuesto caracterizado porque responde a la formula 1 donde: R1 es NHR3 o OR4; R2 es CH3 o CI; R3 es H, C1-4 alquilo ciclopropilo, ciclopropilciclopropilo, ciclopropilmetilo o metilciclopropilo; y R4 es H o C1-4 alquilo; que comprende poner en contacto (1) un compuesto de formula 2 donde X es Br o CI; con (2) un reactivo de cianuro metálico, (3) un reactivo sal de cobre(l), (4) un reactivo sal yoduro y (5) al menos un compuesto de formula 3 donde cada R5, R6, R7, R8 y R9 es independientemente H, C1-12 alquilo, C1-6 alcoxi o NR10R11 y cada R10 y R11 es independientemente H o C1-6 alquilo; o un par de R10 y R11 unidos al mismo nitrogeno se toman juntos como -CH2CH2CH2-, -CH2CH2CH2CH2-, -CH2(CH2)3CH2-, -CH2CH2OCH2CH2-, -CH2CH2N(R16)CH2CH2- o -CH2CH2S(O)nCH2CH2, cada uno opcionalmente sustituido con hasta 4 sustituyentes seleccionados independientemente entre C1-4 alquilo; cada R16 es independientemente H o C1-12 alquilo; y cada n es independientemente 0, 1 o 2; con la salvedad de que cuando X es CI, luego R2 es metilo. Reivindicacion 17: Un método para preparar un compuesto caracterizado porque responde a la formula 4 donde R2 es CH3 o CI; R3 es H, C1-4 alquilo, ciclopropilo, ciclopropilciclopropilo, ciclopropilmetilo, o metilciclopropilo; Z es CR15 o N; R12 es CI, Br, CF3, OCF2H o OCH2CF3; R13 es F, CI o Br; R14 es H, F o CI; y R15 es H, F, CI o Br; usando un compuesto de formula 1 donde R1 es NHR3 o OR4; y R4 es H o C1-4 alquilo; caracterizado por: preparar dicho compuesto de formula 1 mediante el método de la reivindicacion 1.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US845807P | 2007-12-19 | 2007-12-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR069838A1 true AR069838A1 (es) | 2010-02-24 |
Family
ID=40521896
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080105556A AR069838A1 (es) | 2007-12-19 | 2008-12-19 | Proceso para la preparacion de derivados de acido 2-amino-5-cianobenzoico |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8247570B2 (es) |
| EP (1) | EP2231592B1 (es) |
| JP (1) | JP5398734B2 (es) |
| KR (1) | KR101587296B1 (es) |
| CN (1) | CN101970397B (es) |
| AR (1) | AR069838A1 (es) |
| AU (1) | AU2008343227B2 (es) |
| BR (1) | BRPI0819568B1 (es) |
| CA (1) | CA2709952A1 (es) |
| CL (1) | CL2008003756A1 (es) |
| CO (1) | CO6300860A2 (es) |
| IL (1) | IL206390A (es) |
| RU (1) | RU2010129913A (es) |
| TW (1) | TWI432421B (es) |
| WO (1) | WO2009085816A1 (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010535156A (ja) | 2007-08-03 | 2010-11-18 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ウイルスポリメラーゼ阻害剤 |
| US8476257B2 (en) | 2007-12-19 | 2013-07-02 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| TWI431000B (zh) | 2008-03-05 | 2014-03-21 | Du Pont | 製備２－胺基－５－氰基苯甲酸衍生物之方法 |
| TW201247631A (en) | 2011-04-28 | 2012-12-01 | Du Pont | Herbicidal pyrazinones |
| DK2729444T3 (en) * | 2011-07-08 | 2017-12-04 | Bayer Ip Gmbh | METHOD FOR PREPARING 2-AMINO-5-CYANO-N, 3-DIMETHYLBENZAMIDE |
| EP2742027A1 (en) | 2011-08-12 | 2014-06-18 | Basf Se | N-thio-anthranilamide compounds and their use as pesticides |
| AR087515A1 (es) | 2011-08-12 | 2014-03-26 | Basf Se | Compuestos de n-tio-antranilamida y sus usos como plaguicidas |
| MX2014001609A (es) | 2011-08-12 | 2014-05-01 | Basf Se | Compuestos de n-tio-antranilamida y sus usos como plaguicidas. |
| IN2014CN01025A (es) | 2011-08-12 | 2015-04-10 | Basf Se | |
| BR112014015531A8 (pt) | 2011-12-21 | 2017-07-04 | Basf Se | compostos, composição agrícola ou veterinária, métodos, semente e utilização d eum composto |
| WO2013113789A1 (en) | 2012-02-02 | 2013-08-08 | Basf Se | N-thio-anthranilamide compounds and their use as pesticides |
| CN109970707A (zh) | 2012-02-07 | 2019-07-05 | 拜耳知识产权有限责任公司 | 取代的邻氨基苯甲酸衍生物的制备方法 |
| CN104003976B (zh) * | 2014-05-07 | 2016-03-16 | 肇庆市真格生物科技有限公司 | 多取代吡啶基吡唑酰胺及其制备方法和用途 |
| TWI678354B (zh) * | 2014-05-29 | 2019-12-01 | 新加坡商艾佛艾姆希農業新加坡有限公司 | 藉空氣氧化製備３-甲基-２-硝基苯甲酸之製程 |
| CN105461683B (zh) * | 2015-11-18 | 2019-01-15 | 江苏省农用激素工程技术研究中心有限公司 | 邻氨基苯甲酰胺化合物的制备方法 |
| WO2020117493A1 (en) * | 2018-12-03 | 2020-06-11 | Fmc Corporation | Method for preparing n-phenylpyrazole-1-carboxamides |
| WO2020170092A1 (en) | 2019-02-18 | 2020-08-27 | Pi Industries Ltd. | A process for preparing anthranilic diamides and intermediates thereof |
| US11718584B2 (en) | 2019-02-22 | 2023-08-08 | Pi Industries Ltd. | Process for the synthesis anthranilic diamide compounds and intermediates thereof |
| TW202222162A (zh) | 2020-09-26 | 2022-06-16 | 印度商皮埃企業有限公司 | 鄰胺苯甲酸／醯胺化合物及其中間體的合成方法 |
| EP4380363A1 (en) | 2021-08-05 | 2024-06-12 | Syngenta Crop Protection AG | Method for controlling diamide resistant pests & compounds therefor |
| WO2024038436A1 (en) | 2022-08-16 | 2024-02-22 | Adama Makhteshim Ltd. | Process for preparing cyantraniliprole via amino-cyano-benzene derivative |
| WO2024116197A1 (en) * | 2022-11-30 | 2024-06-06 | Natco Pharma Limited | An improved process for the preparation of intermediate of cyantraniliprole |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005534700A (ja) | 2002-08-02 | 2005-11-17 | マサチューセッツ インスティテュート オブ テクノロジー | 銅触媒による炭素−ヘテロ原子および炭素−炭素結合の形成 |
| IN243219B (es) | 2003-01-28 | 2010-10-01 | Du Pont | |
| MY140912A (en) * | 2004-07-26 | 2010-01-29 | Du Pont | Mixtures of anthranilamide invertebrate pest control agents |
| TWI363756B (en) * | 2004-12-07 | 2012-05-11 | Du Pont | Method for preparing n-phenylpyrazole-1-carboxamides |
| DE102006042439A1 (de) | 2006-09-09 | 2008-03-27 | Saltigo Gmbh | Verfahren zur katalytischen Herstellung von aromatischen oder heteroaromatischen Nitrilen |
| TWI415827B (zh) * | 2006-12-21 | 2013-11-21 | Du Pont | 製備２-胺基-５-氰基苯甲酸衍生物之方法 |
| TWI431000B (zh) | 2008-03-05 | 2014-03-21 | Du Pont | 製備２－胺基－５－氰基苯甲酸衍生物之方法 |
-
2008
- 2008-12-16 TW TW097149061A patent/TWI432421B/zh active
- 2008-12-17 BR BRPI0819568-4A patent/BRPI0819568B1/pt active IP Right Grant
- 2008-12-17 CA CA2709952A patent/CA2709952A1/en not_active Abandoned
- 2008-12-17 RU RU2010129913/04A patent/RU2010129913A/ru unknown
- 2008-12-17 CL CL2008003756A patent/CL2008003756A1/es unknown
- 2008-12-17 EP EP08868511.0A patent/EP2231592B1/en active Active
- 2008-12-17 CN CN200880126979.XA patent/CN101970397B/zh active Active
- 2008-12-17 JP JP2010539729A patent/JP5398734B2/ja active Active
- 2008-12-17 US US12/809,072 patent/US8247570B2/en active Active
- 2008-12-17 KR KR1020107015703A patent/KR101587296B1/ko active Active
- 2008-12-17 AU AU2008343227A patent/AU2008343227B2/en active Active
- 2008-12-17 WO PCT/US2008/087151 patent/WO2009085816A1/en not_active Ceased
- 2008-12-19 AR ARP080105556A patent/AR069838A1/es unknown
-
2010
- 2010-06-15 IL IL206390A patent/IL206390A/en active IP Right Grant
- 2010-06-18 CO CO10073860A patent/CO6300860A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TWI432421B (zh) | 2014-04-01 |
| CO6300860A2 (es) | 2011-07-21 |
| AU2008343227A1 (en) | 2009-07-09 |
| CN101970397A (zh) | 2011-02-09 |
| CL2008003756A1 (es) | 2009-11-27 |
| KR20100098443A (ko) | 2010-09-06 |
| TW200934770A (en) | 2009-08-16 |
| EP2231592B1 (en) | 2016-02-17 |
| JP5398734B2 (ja) | 2014-01-29 |
| BRPI0819568B1 (pt) | 2018-02-06 |
| AU2008343227B2 (en) | 2013-08-01 |
| KR101587296B1 (ko) | 2016-01-21 |
| CN101970397B (zh) | 2014-04-16 |
| US20120130080A1 (en) | 2012-05-24 |
| IL206390A (en) | 2014-06-30 |
| EP2231592A1 (en) | 2010-09-29 |
| IL206390A0 (en) | 2010-12-30 |
| JP2011507872A (ja) | 2011-03-10 |
| US8247570B2 (en) | 2012-08-21 |
| BRPI0819568A2 (pt) | 2017-07-04 |
| RU2010129913A (ru) | 2012-01-27 |
| CA2709952A1 (en) | 2009-07-09 |
| WO2009085816A1 (en) | 2009-07-09 |
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Legal Events
| Date | Code | Title | Description |
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| FB | Suspension of granting procedure |