AR059554A1 - Acido nucleico derivado de perkinsus marinus que codifica una 9-elongasa, delta 8-desaturasa y delta 5-desaturasa" - Google Patents
Acido nucleico derivado de perkinsus marinus que codifica una 9-elongasa, delta 8-desaturasa y delta 5-desaturasa"Info
- Publication number
- AR059554A1 AR059554A1 ARP070100695A ARP070100695A AR059554A1 AR 059554 A1 AR059554 A1 AR 059554A1 AR P070100695 A ARP070100695 A AR P070100695A AR P070100695 A ARP070100695 A AR P070100695A AR 059554 A1 AR059554 A1 AR 059554A1
- Authority
- AR
- Argentina
- Prior art keywords
- nucleic acid
- seq
- desaturase
- acid sequence
- desaturasa
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 9
- 241001442530 Perkinsus marinus Species 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 6
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 102100034542 Acyl-CoA (8-3)-desaturase Human genes 0.000 abstract 3
- 108010073542 Delta-5 Fatty Acid Desaturase Proteins 0.000 abstract 3
- 108010022240 delta-8 fatty acid desaturase Proteins 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 3
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229940114079 arachidonic acid Drugs 0.000 abstract 1
- 235000021342 arachidonic acid Nutrition 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 abstract 1
- 235000020778 linoleic acid Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Nutrition Science (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Fats And Perfumes (AREA)
Abstract
Todas las secuencias codificadoras pueden transcribirse como una sola transcripcion. Construcciones genéticas que comprenden tales secuencias, vectores de clonacion y expresion que expresan las enzimas así como un proceso para convertir ácido linoleico en ácido araquidonico. Reivindicacion 1: Una secuencia de ácido nucleico aislada que codifica polipéptidos con actividad de delta9-elongasa, delta8-desaturasa y delta5-desaturasa, caracterizada porque se selecciona del grupo que consiste de: a) una secuencia de ácido nucleico que comprende residuos de ácido nucleico 7668 a 12077 de SEQ ID N°: 1 o un homologo del mismo; b) una secuencia de ácido nucleico que se hibridiza en condiciones rigurosas con una secuencia de ácido nucleico que comprende residuos de ácido nucleico 7668 a 12077 de SEQ ID N°: 1; c) una secuencia de ácido nucleico aislada que codifica polipéptidos con actividad de delta9-elongasa, delta8-desaturasa y delta5-desaturasa, donde los polipéptidos se seleccionan del grupo que consiste de SEQ ID N°: 2, 3 y 4; d) un derivado de una secuencia de ácido nucleico de SEQ ID N°: 1 que codifica polipéptidos con al menos 40% de identidad a nivel del amino ácido con SEQ ID N°: 2, SEQ ID N°: 3 y SEQ ID N°:4, donde dichos polipéptidos tienen actividad de delta9-elongasa, delta8-desaturasa y delta5-desaturasa.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0603160.3A GB0603160D0 (en) | 2006-02-16 | 2006-02-16 | Nucleic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR059554A1 true AR059554A1 (es) | 2008-04-09 |
Family
ID=36141974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070100695A AR059554A1 (es) | 2006-02-16 | 2007-02-16 | Acido nucleico derivado de perkinsus marinus que codifica una 9-elongasa, delta 8-desaturasa y delta 5-desaturasa" |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8119861B2 (es) |
| EP (2) | EP2380984B1 (es) |
| CN (1) | CN101421399B (es) |
| AR (1) | AR059554A1 (es) |
| AT (1) | ATE510923T1 (es) |
| AU (1) | AU2007216359B2 (es) |
| BR (1) | BRPI0707944B1 (es) |
| CA (2) | CA3006116C (es) |
| DK (1) | DK1984502T3 (es) |
| ES (1) | ES2367220T3 (es) |
| GB (1) | GB0603160D0 (es) |
| WO (1) | WO2007093776A2 (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8785727B2 (en) | 2008-04-30 | 2014-07-22 | Rothamsted Research Ltd. | Desaturase and method for the production of polyunsaturated fatty acids in transgenic organisms |
| WO2010011997A2 (en) | 2008-07-25 | 2010-01-28 | Mary Kay Inc. | Compositions comprising docynia delavajy extract and/or elaeagnus lancelotus extract |
| CN102317459A (zh) | 2008-11-18 | 2012-01-11 | 联邦科学技术研究组织 | 产生ω-3脂肪酸的酶和方法 |
| PL2376638T3 (pl) | 2008-12-12 | 2014-01-31 | Basf Plant Science Gmbh | Desaturazy oraz sposób wytwarzania wielonienasyconych kwasów tłuszczowych w organizmach transgenicznych |
| WO2010130725A1 (en) | 2009-05-13 | 2010-11-18 | Basf Plant Science Company Gmbh | Acyltransferases and uses thereof in fatty acid production |
| WO2010142522A2 (en) | 2009-06-08 | 2010-12-16 | Basf Plant Science Company Gmbh | Novel fatty acid elongation components and uses thereof |
| US9493520B2 (en) | 2009-07-17 | 2016-11-15 | Basf Plant Science Company Gmbh | Fatty acid desaturases and elongases and uses thereof |
| EP3178937B1 (en) | 2009-08-31 | 2018-11-07 | BASF Plant Science Company GmbH | Regulatory nucleic acid molecules for enhancing seed-specific gene expression in plants promoting enhanced polyunsaturated fatty acid synthesis |
| CA2780956A1 (en) | 2009-11-24 | 2011-06-03 | Basf Plant Science Company Gmbh | Novel fatty acid desaturase and uses thereof |
| US9347049B2 (en) | 2009-11-24 | 2016-05-24 | Basf Plant Science Company Gmbh | Fatty acid elongase and uses thereof |
| WO2011161093A1 (en) | 2010-06-25 | 2011-12-29 | Basf Plant Science Company Gmbh | Acyltransferases and uses therof in fatty acid production |
| US9458477B2 (en) | 2010-10-21 | 2016-10-04 | Basf Plant Science Company Gmbh | Fatty acid desaturases, elongases, elongation components and uses thereof |
| HUE033766T2 (en) | 2012-06-15 | 2018-01-29 | Commw Scient Ind Res Org | Production of long chain polyunsaturated fatty acids in plant cells |
| US9879234B2 (en) | 2012-08-03 | 2018-01-30 | Basf Plant Science Company Gmbh | Enzymes, enzyme components and uses thereof |
| KR101424116B1 (ko) * | 2012-10-31 | 2014-08-04 | 대한민국 | 파이토프토라 유래 델타-6 불포화효소 유전자로 형질전환된 들깨 및 이의 제조방법 |
| CA3241340A1 (en) | 2013-12-18 | 2015-06-25 | Grains Research And Development Corporation | Lipid comprising long chain polyunsaturated fatty acids |
| US10045540B2 (en) | 2014-04-01 | 2018-08-14 | Fayetteville State University | Pest control composition |
| EP3160482A4 (en) | 2014-06-27 | 2018-02-14 | Commonwealth Scientific and Industrial Research Organisation | Lipid comprising docosapentaenoic acid |
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| ATE479757T1 (de) * | 2004-06-04 | 2010-09-15 | Fluxome Sciences As | Stoffwechseltechnisch hergestellte zellen zur produktion mehrfach ungesättigter fettsäuren |
| EP1758991B1 (en) | 2004-06-25 | 2013-01-16 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| WO2007061742A1 (en) * | 2005-11-23 | 2007-05-31 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
-
2006
- 2006-02-16 GB GBGB0603160.3A patent/GB0603160D0/en not_active Ceased
-
2007
- 2007-02-13 EP EP11158870.3A patent/EP2380984B1/en not_active Not-in-force
- 2007-02-13 BR BRPI0707944A patent/BRPI0707944B1/pt not_active IP Right Cessation
- 2007-02-13 US US12/279,560 patent/US8119861B2/en active Active
- 2007-02-13 WO PCT/GB2007/000491 patent/WO2007093776A2/en not_active Ceased
- 2007-02-13 CA CA3006116A patent/CA3006116C/en active Active
- 2007-02-13 CN CN2007800131487A patent/CN101421399B/zh not_active Expired - Fee Related
- 2007-02-13 AT AT07731971T patent/ATE510923T1/de not_active IP Right Cessation
- 2007-02-13 CA CA2641425A patent/CA2641425C/en active Active
- 2007-02-13 DK DK07731971.3T patent/DK1984502T3/da active
- 2007-02-13 EP EP07731971A patent/EP1984502B1/en not_active Not-in-force
- 2007-02-13 ES ES07731971T patent/ES2367220T3/es active Active
- 2007-02-13 AU AU2007216359A patent/AU2007216359B2/en not_active Ceased
- 2007-02-16 AR ARP070100695A patent/AR059554A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB0603160D0 (en) | 2006-03-29 |
| EP1984502B1 (en) | 2011-05-25 |
| BRPI0707944A2 (pt) | 2011-05-17 |
| EP2380984A2 (en) | 2011-10-26 |
| EP1984502A2 (en) | 2008-10-29 |
| ATE510923T1 (de) | 2011-06-15 |
| WO2007093776A3 (en) | 2007-12-06 |
| ES2367220T3 (es) | 2011-10-31 |
| CN101421399B (zh) | 2013-05-29 |
| CA3006116A1 (en) | 2007-08-23 |
| CA2641425A1 (en) | 2007-08-23 |
| US20090019559A1 (en) | 2009-01-15 |
| AU2007216359B2 (en) | 2013-05-23 |
| CA2641425C (en) | 2020-06-30 |
| CN101421399A (zh) | 2009-04-29 |
| EP2380984B1 (en) | 2017-12-27 |
| BRPI0707944B1 (pt) | 2017-04-11 |
| DK1984502T3 (da) | 2011-08-29 |
| EP2380984A3 (en) | 2011-11-30 |
| CA3006116C (en) | 2021-09-21 |
| AU2007216359A1 (en) | 2007-08-23 |
| WO2007093776A2 (en) | 2007-08-23 |
| US8119861B2 (en) | 2012-02-21 |
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