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AR049096A1 - Formulacion en aerosol sin gas propelente para la inhalacion de beta-agonistas - Google Patents

Formulacion en aerosol sin gas propelente para la inhalacion de beta-agonistas

Info

Publication number
AR049096A1
AR049096A1 ARP050101959A ARP050101959A AR049096A1 AR 049096 A1 AR049096 A1 AR 049096A1 AR P050101959 A ARP050101959 A AR P050101959A AR P050101959 A ARP050101959 A AR P050101959A AR 049096 A1 AR049096 A1 AR 049096A1
Authority
AR
Argentina
Prior art keywords
alkyl
alkoxy
halogen
hydrogen
enantiomers
Prior art date
Application number
ARP050101959A
Other languages
English (en)
Inventor
Michael Aven
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34979667&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR049096(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of AR049096A1 publication Critical patent/AR049096A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/04Amoebicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Reivindicacion 1: Formulacion medicamentosa que contiene como unico principio activo uno o varios compuestos de la formula general (1), en la que significan: R1 es hidrogeno, alquilo C1-4, alcoxi C1-4 o halogeno; R2 es hidrogeno, alquilo C1-4, alcoxi C1-4 o halogeno; R3 es hidrogeno, alquilo C1-4, alcoxi C1-4 o halogeno, OH, -O-alquilenC1-4-COOH u -O-alquilen-C1-4-COO-alquiloC1-4; X- anion de carga negativa simple, con preferencia un anion de carga negativa simple seleccionado del grupo compuesto por cloruro, bromuro, yoduro, sulfato, fosfato, metansulfonato, nitrato, maleato, acetato, benzoato, citrato, salicilato, trifluoroacetato, fumarato, tartrato, oxalato, succinato, benzoato y ptoluensulfonato; eventualmente en forma de sus tautomeros, enantiomeros, mezclas de enantiomeros, racematos o solvatos, al menos un ácido farmacologicamente tolerable, eventualmente otros coadyuvantes y/o formadores de complejos farmacologicamente tolerables, y como disolvente agua, etanol o una mezcla de agua y etanol.
ARP050101959A 2004-05-14 2005-05-13 Formulacion en aerosol sin gas propelente para la inhalacion de beta-agonistas AR049096A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004024452A DE102004024452A1 (de) 2004-05-14 2004-05-14 Aerosolformulierung für die Inhalation von Betaagonisten

Publications (1)

Publication Number Publication Date
AR049096A1 true AR049096A1 (es) 2006-06-28

Family

ID=34979667

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050101959A AR049096A1 (es) 2004-05-14 2005-05-13 Formulacion en aerosol sin gas propelente para la inhalacion de beta-agonistas

Country Status (26)

Country Link
EP (1) EP1809293B1 (es)
JP (1) JP4620730B2 (es)
KR (1) KR101288791B1 (es)
CN (1) CN101056640A (es)
AR (1) AR049096A1 (es)
AU (1) AU2005244414B2 (es)
BR (1) BRPI0511135B8 (es)
CA (1) CA2564379C (es)
DE (1) DE102004024452A1 (es)
DK (1) DK1809293T3 (es)
EA (1) EA012583B1 (es)
EC (1) ECSP067004A (es)
ES (1) ES2575925T3 (es)
HU (1) HUE027780T2 (es)
IL (1) IL179218A (es)
MX (1) MXPA06013216A (es)
MY (1) MY148403A (es)
NO (1) NO20065030L (es)
PE (1) PE20060311A1 (es)
PL (1) PL1809293T3 (es)
SG (1) SG152265A1 (es)
TW (1) TWI356703B (es)
UA (1) UA87312C2 (es)
UY (1) UY28891A1 (es)
WO (1) WO2005110421A2 (es)
ZA (1) ZA200607462B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
MX2008001976A (es) 2005-08-15 2008-03-25 Boehringer Ingelheim Int Procedimiento para la preparacion de betamimeticos.
EA200801139A1 (ru) * 2005-11-09 2008-10-30 Бёрингер Ингельхайм Интернациональ Гмбх Композиция для аэрозольной ингаляции
UY30543A1 (es) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Formulacion de aerosol para la inhalacion de beta- agonistas
WO2010057927A1 (en) * 2008-11-21 2010-05-27 Boehringer Ingelheim International Gmbh Aerosol formulation for the inhalation of beta agonists
EP2358350A1 (en) * 2008-11-21 2011-08-24 Boehringer Ingelheim International GmbH Aerosol formulation for the inhalation of beta agonists
JP2015533131A (ja) 2012-10-09 2015-11-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 咳を治療するためのベータ2−アドレナリン受容体作動薬
WO2018108669A1 (en) 2016-12-12 2018-06-21 Boehringer Ingelheim International Gmbh Nintedanib for use in methods for the treatment of interstitial lung diseases by coadministration with olodaterol
BR112022010802A2 (pt) * 2019-12-05 2022-08-23 Syngenta Crop Protection Ag Processo de um passo para a preparação de derivados de feniletilamina

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3134590A1 (de) * 1981-09-01 1983-03-10 Boehringer Ingelheim KG, 6507 Ingelheim Neue benzo-heterocyclen
US4460581A (en) * 1982-10-12 1984-07-17 Boehringer Ingelheim Kg (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones
JPH0637388B2 (ja) * 1986-02-17 1994-05-18 千寿製薬株式会社 水性液剤
GB9405019D0 (en) * 1994-03-15 1994-04-27 Smithkline Beecham Plc Novel compounds
DE10253282A1 (de) * 2002-11-15 2004-05-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
EP1781298B1 (de) * 2004-04-22 2012-01-04 Boehringer Ingelheim International GmbH Arzneinmittelkombinationen enthaltend benzoxazine zur behandlung von atemwegserkrankungen
DE102004019539A1 (de) * 2004-04-22 2005-11-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von Atemwegserkrankungen
DE102004024454A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102004024451A1 (de) * 2004-05-14 2005-12-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverformulierungen für die Inhalation, die Enantiomerenreine Betaagonisten enthalten

Also Published As

Publication number Publication date
CA2564379A1 (en) 2005-11-24
JP2007537188A (ja) 2007-12-20
TW200608981A (en) 2006-03-16
EP1809293B1 (de) 2016-03-16
IL179218A0 (en) 2007-03-08
KR101288791B1 (ko) 2013-07-29
BRPI0511135B1 (pt) 2019-11-12
PE20060311A1 (es) 2006-05-08
ES2575925T3 (es) 2016-07-04
EA012583B1 (ru) 2009-10-30
WO2005110421A3 (de) 2006-03-16
UY28891A1 (es) 2005-12-30
WO2005110421A2 (de) 2005-11-24
MY148403A (en) 2013-04-30
NO20065030L (no) 2006-11-30
BRPI0511135A (pt) 2007-11-27
EA200602017A1 (ru) 2007-06-29
AU2005244414A1 (en) 2005-11-24
SG152265A1 (en) 2009-05-29
HUE027780T2 (en) 2016-11-28
PL1809293T3 (pl) 2016-09-30
DK1809293T3 (en) 2016-06-20
KR20070022084A (ko) 2007-02-23
ZA200607462B (en) 2008-06-25
EP1809293A2 (de) 2007-07-25
IL179218A (en) 2012-10-31
ECSP067004A (es) 2007-02-28
CA2564379C (en) 2013-07-30
TWI356703B (en) 2012-01-21
DE102004024452A1 (de) 2005-12-08
CN101056640A (zh) 2007-10-17
BRPI0511135B8 (pt) 2021-05-25
AU2005244414B2 (en) 2010-12-09
UA87312C2 (ru) 2009-07-10
MXPA06013216A (es) 2007-02-08
JP4620730B2 (ja) 2011-01-26

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