AR049055A2 - Una tableta rapidamente desintegrable para la administracion por via oral - Google Patents
Una tableta rapidamente desintegrable para la administracion por via oralInfo
- Publication number
- AR049055A2 AR049055A2 ARP050102043A ARP050102043A AR049055A2 AR 049055 A2 AR049055 A2 AR 049055A2 AR P050102043 A ARP050102043 A AR P050102043A AR P050102043 A ARP050102043 A AR P050102043A AR 049055 A2 AR049055 A2 AR 049055A2
- Authority
- AR
- Argentina
- Prior art keywords
- component
- centipoise
- methylcellulose
- viscosity
- microcrystalline cellulose
- Prior art date
Links
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 4
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 3
- 229920000609 methyl cellulose Polymers 0.000 abstract 3
- 239000001923 methylcellulose Substances 0.000 abstract 3
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 3
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 3
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 235000019359 magnesium stearate Nutrition 0.000 abstract 2
- 235000019333 sodium laurylsulphate Nutrition 0.000 abstract 2
- 239000008109 sodium starch glycolate Substances 0.000 abstract 2
- 229920003109 sodium starch glycolate Polymers 0.000 abstract 2
- 229940079832 sodium starch glycolate Drugs 0.000 abstract 2
- 229920002261 Corn starch Polymers 0.000 abstract 1
- 229920000881 Modified starch Polymers 0.000 abstract 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 abstract 1
- 239000008120 corn starch Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 239000008141 laxative Substances 0.000 abstract 1
- 230000002475 laxative effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 229940069328 povidone Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/717—Celluloses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
Una tableta rápidamente desintegrable para la administracion oral, con eficacia como laxante, que comprende: a) gránulos que tienen un componente intragranular que comprende metilcelulosa de una viscosidad de mayor 1000 centipoise como unico ingrediente activo; y un diluyente seleccionado a partir del grupo formado por celulosa microcristalina, almidon de maíz, almidon pregelatinizado, y mezclas de los mismos; o b) un componente intragranular que comprende metilcelulosa que tiene una viscosidad de mayor 3000 centipoise como unico ingrediente activo, celulosa microcristalina, glicolato de almidon sodico, Povidona, y un componente extragranular que comprende lauril sulfato de sodio y estearato de magnesio; o c) un componente intragranular que comprende metilcelulosa que tiene una viscosidad de mayor 3000 centipoise, celulosa microcristalina, glicolato de almidon sodico, y un componente extragranular que comprende lauril sulfato de sodio y estearato de magnesio.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5689997P | 1997-08-22 | 1997-08-22 | |
| US8164498P | 1998-04-14 | 1998-04-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR049055A2 true AR049055A2 (es) | 2006-06-21 |
Family
ID=26735830
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980104077A AR016827A1 (es) | 1997-08-22 | 1998-08-18 | PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA |
| ARP050102043A AR049055A2 (es) | 1997-08-22 | 2005-05-18 | Una tableta rapidamente desintegrable para la administracion por via oral |
| ARP050102065A AR049057A2 (es) | 1997-08-22 | 2005-05-19 | Una tableta rapidamente desintegrable para la administracion por via oral |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980104077A AR016827A1 (es) | 1997-08-22 | 1998-08-18 | PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050102065A AR049057A2 (es) | 1997-08-22 | 2005-05-19 | Una tableta rapidamente desintegrable para la administracion por via oral |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US6372253B1 (es) |
| EP (1) | EP1014949A4 (es) |
| JP (1) | JP2001513546A (es) |
| KR (1) | KR20010023198A (es) |
| CN (1) | CN1240374C (es) |
| AR (3) | AR016827A1 (es) |
| AU (1) | AU745682B2 (es) |
| BR (1) | BR9811987A (es) |
| CA (1) | CA2301132C (es) |
| CO (1) | CO4960646A1 (es) |
| EA (1) | EA003663B1 (es) |
| HU (1) | HUP0003186A3 (es) |
| MY (1) | MY137768A (es) |
| NZ (1) | NZ502890A (es) |
| PL (1) | PL338786A1 (es) |
| TW (1) | TWI228421B (es) |
| UA (1) | UA70926C2 (es) |
| WO (1) | WO1999009959A1 (es) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
| AR016827A1 (es) * | 1997-08-22 | 2001-08-01 | Smithkline Beecham Corp | PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA |
| AR017512A1 (es) | 1997-08-22 | 2001-09-12 | Smithkline Beecham Corp | Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas |
| US6348264B1 (en) | 1998-04-27 | 2002-02-19 | Roquette Freres | Process for producing low de starch hydrolysates by nanofiltration fractionation, products obtained thereby, and use of such products |
| EP1112063A4 (en) * | 1998-09-08 | 2009-05-13 | Smithkline Beecham Corp | TABLETS BASED ON AN LPSTATINE DERIVATIVE AND SOLUBLE FIBERS |
| DE50001734D1 (de) * | 2000-10-24 | 2003-05-15 | Fit Gmbh | Coprozessiertes Sprengmittelgranulat |
| SI1413331T1 (sl) * | 2001-01-26 | 2008-02-29 | Schering Corp | Kombinacije fenofibrata peroksisomskega proliferator aktivirajocega receptorja (PPAR) z ezetimib zaviralcem absorpcije sterola za vaskularne indikacije |
| US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
| EP1574215B1 (en) | 2002-12-16 | 2015-07-15 | Kissei Pharmaceutical Co., Ltd. | Solid drug for oral use |
| US8367111B2 (en) * | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
| MXPA06000702A (es) * | 2003-07-23 | 2006-04-11 | Perrigo L Co | Composicion que contiene fibra celulosica. |
| US7198653B2 (en) | 2003-07-31 | 2007-04-03 | Delavau Llc | Calcium carbonate granulation |
| US7390503B1 (en) | 2003-08-22 | 2008-06-24 | Barr Laboratories, Inc. | Ondansetron orally disintegrating tablets |
| KR20060126688A (ko) * | 2003-12-09 | 2006-12-08 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 약물-함유 입자 및 그 입자를 함유하는 고형 제제 |
| US8747895B2 (en) * | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
| US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
| WO2006047493A2 (en) | 2004-10-21 | 2006-05-04 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
| US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
| US7344907B2 (en) * | 2004-11-19 | 2008-03-18 | International Business Machines Corporation | Apparatus and methods for encapsulating microelectromechanical (MEM) devices on a wafer scale |
| CA2597688C (en) * | 2005-03-23 | 2013-09-10 | Bpsi Holdings, Llc | Agglomerated starch compositions |
| US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
| HUE026040T2 (en) * | 2005-05-05 | 2016-05-30 | Bristol-Myers Squibb Holdings Ireland | Formulations of SRC / ABL inhibitor |
| AU2005334837B2 (en) * | 2005-07-29 | 2012-07-19 | Stichting Groningen Centre For Drug Research | PH-controlled pulsatile delivery system, methods for preparation and use thereof |
| PE20070698A1 (es) | 2005-11-14 | 2007-08-17 | Teijin Pharma Ltd | Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol |
| US9138414B1 (en) | 2006-09-15 | 2015-09-22 | Delavau Llc | Calcium supplement having enhanced absorption |
| RU2429709C2 (ru) | 2006-11-07 | 2011-09-27 | Дзе Проктер Энд Гэмбл Компани | Экструдированная принимаемая с пищей композиция, содержащая клетчатку, и способ ее изготовления |
| JP5284967B2 (ja) * | 2007-02-01 | 2013-09-11 | 武田薬品工業株式会社 | 打錠障害を生じない錠剤製剤 |
| US7767248B2 (en) * | 2007-02-02 | 2010-08-03 | Overly Iii Harry J | Soft chew confectionary with high fiber and sugar content and method for making same |
| US8273798B2 (en) * | 2007-06-04 | 2012-09-25 | Shear Kershman Laboratories | Tamper resistant lipid-based oral dosage form for opioid agonists |
| US8420700B1 (en) * | 2008-06-04 | 2013-04-16 | James M. Bausch | Tamper resistant lipid-based oral dosage form for sympathomimetic amines |
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| WO2010055002A1 (en) * | 2008-11-17 | 2010-05-20 | Basf Se | Starch-containing granular formulation |
| MX2012006240A (es) | 2009-12-02 | 2012-10-03 | Aptalis Pharma Ltd | Microcapsulas de fexofenadina y composiciones que contienen las mismas. |
| US20110212171A1 (en) * | 2010-01-08 | 2011-09-01 | Eurand, Inc. | Taste masked topiramate composition and an orally disintegrating tablet comprising the same |
| TWI564008B (zh) | 2010-09-30 | 2017-01-01 | 鹽野義製藥股份有限公司 | 難溶性藥物之溶解性改善製劑 |
| DK2802311T3 (en) * | 2011-10-25 | 2019-04-08 | Expermed S A | SUBLINGUAL PHARMACEUTICAL COMPOSITION CONTAINING AN ANTIHISTAMIN MEDICINE AND PROCEDURE FOR PREPARING THEREOF |
| KR102152873B1 (ko) | 2012-07-27 | 2020-09-08 | 레드힐 바이오파마 엘티디 | 결장 배출의 용도를 위한 제형 및 제형의 제조 방법 |
| US11389454B2 (en) * | 2016-09-07 | 2022-07-19 | Celgene Corporation | Tablet compositions |
| MX2023003432A (es) | 2020-09-29 | 2023-08-04 | Millicent Pharma Ltd | Formulaciones orodispersables. |
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| AR016827A1 (es) * | 1997-08-22 | 2001-08-01 | Smithkline Beecham Corp | PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA |
-
1998
- 1998-08-18 AR ARP980104077A patent/AR016827A1/es unknown
- 1998-08-19 CO CO98047415A patent/CO4960646A1/es unknown
- 1998-08-20 MY MYPI98003810A patent/MY137768A/en unknown
- 1998-08-21 PL PL98338786A patent/PL338786A1/xx not_active Application Discontinuation
- 1998-08-21 WO PCT/US1998/017440 patent/WO1999009959A1/en not_active Ceased
- 1998-08-21 AU AU91146/98A patent/AU745682B2/en not_active Ceased
- 1998-08-21 HU HU0003186A patent/HUP0003186A3/hu unknown
- 1998-08-21 UA UA2000020918A patent/UA70926C2/uk unknown
- 1998-08-21 CA CA002301132A patent/CA2301132C/en not_active Expired - Fee Related
- 1998-08-21 EP EP98943322A patent/EP1014949A4/en not_active Withdrawn
- 1998-08-21 KR KR1020007001826A patent/KR20010023198A/ko not_active Abandoned
- 1998-08-21 TW TW087113822A patent/TWI228421B/zh not_active IP Right Cessation
- 1998-08-21 BR BR9811987-7A patent/BR9811987A/pt not_active Application Discontinuation
- 1998-08-21 EA EA200000245A patent/EA003663B1/ru not_active IP Right Cessation
- 1998-08-21 CN CNB988102935A patent/CN1240374C/zh not_active Expired - Fee Related
- 1998-08-21 JP JP2000507350A patent/JP2001513546A/ja active Pending
- 1998-08-21 US US09/485,625 patent/US6372253B1/en not_active Expired - Lifetime
- 1998-08-21 NZ NZ502890A patent/NZ502890A/en unknown
-
2002
- 2002-04-16 US US10/123,569 patent/US7132114B2/en not_active Expired - Lifetime
-
2005
- 2005-05-18 AR ARP050102043A patent/AR049055A2/es unknown
- 2005-05-19 AR ARP050102065A patent/AR049057A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MY137768A (en) | 2009-03-31 |
| EP1014949A4 (en) | 2006-06-21 |
| CN1240374C (zh) | 2006-02-08 |
| KR20010023198A (ko) | 2001-03-26 |
| US7132114B2 (en) | 2006-11-07 |
| EA200000245A1 (ru) | 2000-08-28 |
| AR016827A1 (es) | 2001-08-01 |
| BR9811987A (pt) | 2000-09-05 |
| EP1014949A1 (en) | 2000-07-05 |
| WO1999009959A1 (en) | 1999-03-04 |
| AR049057A2 (es) | 2006-06-21 |
| PL338786A1 (en) | 2000-11-20 |
| US20030049315A1 (en) | 2003-03-13 |
| US6372253B1 (en) | 2002-04-16 |
| CA2301132C (en) | 2007-11-13 |
| CA2301132A1 (en) | 1999-03-04 |
| HUP0003186A2 (hu) | 2001-02-28 |
| HUP0003186A3 (en) | 2001-04-28 |
| TWI228421B (en) | 2005-03-01 |
| JP2001513546A (ja) | 2001-09-04 |
| EA003663B1 (ru) | 2003-08-28 |
| AU9114698A (en) | 1999-03-16 |
| UA70926C2 (uk) | 2004-11-15 |
| NZ502890A (en) | 2002-03-01 |
| CN1276718A (zh) | 2000-12-13 |
| CO4960646A1 (es) | 2000-09-25 |
| AU745682B2 (en) | 2002-03-28 |
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