AR031563A1 - Una composicion farmaceutica para emplear en el tratamiento de trastornos menopausicos o posmenopausicos de estrogenos y acetato de medroxiprogesterona, una unidad de dosificacion farmaceutica y uso de una combinacion de estrogenos conjugados y acetato de medroxiprogesterona para la manufactura de u - Google Patents
Una composicion farmaceutica para emplear en el tratamiento de trastornos menopausicos o posmenopausicos de estrogenos y acetato de medroxiprogesterona, una unidad de dosificacion farmaceutica y uso de una combinacion de estrogenos conjugados y acetato de medroxiprogesterona para la manufactura de uInfo
- Publication number
- AR031563A1 AR031563A1 ARP010101273A ARP010101273A AR031563A1 AR 031563 A1 AR031563 A1 AR 031563A1 AR P010101273 A ARP010101273 A AR P010101273A AR P010101273 A ARP010101273 A AR P010101273A AR 031563 A1 AR031563 A1 AR 031563A1
- Authority
- AR
- Argentina
- Prior art keywords
- conjugated
- treatment
- combination
- acetate
- disorders
- Prior art date
Links
- PSGAAPLEWMOORI-PEINSRQWSA-N medroxyprogesterone acetate Chemical compound C([C@@]12C)CC(=O)C=C1[C@@H](C)C[C@@H]1[C@@H]2CC[C@]2(C)[C@@](OC(C)=O)(C(C)=O)CC[C@H]21 PSGAAPLEWMOORI-PEINSRQWSA-N 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940035811 conjugated estrogen Drugs 0.000 abstract 3
- 229960002985 medroxyprogesterone acetate Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- QTTMOCOWZLSYSV-QWAPEVOJSA-M equilin sodium sulfate Chemical compound [Na+].[O-]S(=O)(=O)OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4C3=CCC2=C1 QTTMOCOWZLSYSV-QWAPEVOJSA-M 0.000 abstract 1
- 238000002657 hormone replacement therapy Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229960004616 medroxyprogesterone Drugs 0.000 abstract 1
- -1 medroxyprogesterone acetates Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
Abstract
Una composicion farmacéutica para emplear en el tratamiento de trastornos menopáusicos o posmenopáusicos que comprende estrogenos conjugados, una dosis de aproximadamente 1,5 mg de acetato de medroxiprogesterona y un vehículo farmacéutico, que ofrezcan una terapia hormonal sustitutiva a pacientes en estado perimenopáusicos, menopáusico y posmenopáusico a través de la administracion continua de combinaciones de estrogenos conjugados y acetatos de medroxiprogesteronas. Se describen además una unidad de dosificacion farmacéutica y uso de combinacion de estrogenos conjugados y acetato de medroxiprogesterona para la manufactura de un medicamento.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19063000P | 2000-03-20 | 2000-03-20 | |
| US26860701P | 2001-02-14 | 2001-02-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR031563A1 true AR031563A1 (es) | 2003-09-24 |
Family
ID=26886279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010101273A AR031563A1 (es) | 2000-03-20 | 2001-03-19 | Una composicion farmaceutica para emplear en el tratamiento de trastornos menopausicos o posmenopausicos de estrogenos y acetato de medroxiprogesterona, una unidad de dosificacion farmaceutica y uso de una combinacion de estrogenos conjugados y acetato de medroxiprogesterona para la manufactura de u |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US20010034340A1 (es) |
| EP (1) | EP1265616B1 (es) |
| JP (1) | JP2003527416A (es) |
| KR (1) | KR100805648B1 (es) |
| CN (1) | CN1239160C (es) |
| AR (1) | AR031563A1 (es) |
| AT (1) | ATE326227T1 (es) |
| AU (2) | AU5003401A (es) |
| BG (1) | BG66075B1 (es) |
| BR (1) | BR0109334A (es) |
| CA (1) | CA2402983A1 (es) |
| CY (1) | CY1105632T1 (es) |
| CZ (1) | CZ20023162A3 (es) |
| DE (1) | DE60119703T2 (es) |
| DK (1) | DK1265616T3 (es) |
| EA (1) | EA005592B1 (es) |
| EE (1) | EE05129B1 (es) |
| ES (1) | ES2261393T3 (es) |
| HK (1) | HK1049449B (es) |
| HR (1) | HRP20020837B1 (es) |
| HU (1) | HUP0302093A3 (es) |
| IL (1) | IL151512A0 (es) |
| MX (1) | MXPA02009116A (es) |
| NO (1) | NO326886B1 (es) |
| NZ (1) | NZ521171A (es) |
| PL (1) | PL201762B1 (es) |
| PT (1) | PT1265616E (es) |
| SK (1) | SK286169B6 (es) |
| TW (1) | TWI271194B (es) |
| WO (1) | WO2001070208A2 (es) |
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| US20010044431A1 (en) * | 2000-03-21 | 2001-11-22 | Rodriguez Gustavo C. | Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium |
| US6245819B1 (en) | 2000-07-21 | 2001-06-12 | Hormos Medical Oy, Ltd. | Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause |
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| EP1857110A3 (en) * | 2001-03-16 | 2008-08-06 | Wyeth | Hormone replacement therapy |
| WO2008150547A1 (en) | 2007-06-04 | 2008-12-11 | The Regents Of The University Of California | Pregnancy hormone combination for treatment of autoimmune diseases |
| US20130203722A1 (en) | 2006-09-26 | 2013-08-08 | Rhonda R. Voskuhl | Estriol therapy for autoimmune and neurodegenerative disease and disorders |
| TWI252111B (en) * | 2001-12-14 | 2006-04-01 | Solvay Pharm Gmbh | Matrix film tablet with controlled release of a natural mixture of conjugated estrogens |
| TW200306846A (en) * | 2002-04-03 | 2003-12-01 | Wyeth Corp | Hormone replacement therapy |
| US20030216366A1 (en) * | 2002-04-03 | 2003-11-20 | Leonard Thomas W. | Step-down estrogen therapy |
| TW200306196A (en) * | 2002-04-03 | 2003-11-16 | Wyeth Corp | Hormone replacement therapy |
| TW200306851A (en) * | 2002-04-29 | 2003-12-01 | Wyeth Corp | Hormone replacement therapy |
| TW200400040A (en) * | 2002-05-17 | 2004-01-01 | Wyeth Corp | Hormone replacement therapy |
| CN101406464A (zh) * | 2002-06-06 | 2009-04-15 | 霍尔莫斯医疗有限公司 | 抑制女性萎缩或治疗或预防与女性萎缩相关的症状的方法 |
| TW200404548A (en) * | 2002-06-25 | 2004-04-01 | Wyeth Corp | Pharmaceutical composition containing cyclothiocarbamate derivatives in treatment of hormone-related conditions |
| MXPA04012419A (es) * | 2002-06-25 | 2005-04-19 | Wyeth Corp | Uso de derivados de tio-oxindol en el tratamiento de condiciones relacionadas con la hormona. |
| US8349819B2 (en) | 2002-10-09 | 2013-01-08 | Dr. Reddy's Laboratories New York, Inc. | Steroid extraction process from urine sources |
| EP1622623A4 (en) * | 2003-04-11 | 2009-03-18 | Barr Lab Inc | METHOD FOR THE ADMINISTRATION OF ESTROGENIC AND TESTED |
| US20060040904A1 (en) * | 2004-08-17 | 2006-02-23 | Ahmed Salah U | Vaginal cream compositions, kits thereof and methods of using thereof |
| AU2006330846A1 (en) | 2005-12-27 | 2007-07-05 | Teva Women's Health, Inc. | Conjugated estrogen compositions, applicators, kits, and methods of making and use thereof |
| CA2644913A1 (en) * | 2006-04-05 | 2007-10-18 | Wyeth | Methods for prevention and treatment of conditions arising from local estrogen deficiency |
| BRPI0719675A2 (pt) * | 2006-11-29 | 2013-12-24 | Wyeth Corp | Comprimido com bicamada de estrogênio/serm e estrogênio/progestina |
| WO2008099060A2 (en) * | 2007-02-14 | 2008-08-21 | Hormos Medical Ltd | Methods for the preparation of fispemifene from ospemifene |
| BRPI0807675B1 (pt) * | 2007-02-14 | 2021-05-18 | Hormos Medical Ltd. | método para a preparação de um composto derivado de trifenilbuteno |
| KR100989093B1 (ko) | 2008-01-18 | 2010-10-25 | 한화제약주식회사 | 생강나무 가지의 추출물을 포함하는 심혈관계 질환의 예방 및 치료용 조성물 |
| US9734496B2 (en) | 2009-05-29 | 2017-08-15 | Paypal, Inc. | Trusted remote attestation agent (TRAA) |
| WO2011097571A2 (en) * | 2010-02-08 | 2011-08-11 | Prairie Pharmaceuticals, Llc | Methods for the use of progestogen as a glucocorticoid sensitizer |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| EP3936133A1 (en) | 2011-11-23 | 2022-01-12 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US9321712B2 (en) | 2012-10-19 | 2016-04-26 | Fermion Oy | Process for the preparation of ospemifene |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
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| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
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| WO2015168000A1 (en) | 2014-04-28 | 2015-11-05 | The Regents Of The University Of California | Estrogen combination for treatment of multiple sclerosis |
| EP3137088B1 (en) | 2014-04-28 | 2023-08-30 | The Regents of The University of California | Pharmaceutical packaging for estriol therapy for the treatment of multiple sclerosis |
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| NL9301562A (nl) * | 1993-09-09 | 1995-04-03 | Saturnus Ag | Preparaat voor substitutietherapie. |
| US5554601A (en) * | 1993-11-05 | 1996-09-10 | University Of Florida | Methods for neuroprotection |
| US5759577A (en) * | 1995-01-17 | 1998-06-02 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
| US5547948A (en) * | 1995-01-17 | 1996-08-20 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
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2001
- 2001-03-15 US US09/808,878 patent/US20010034340A1/en not_active Abandoned
- 2001-03-16 MX MXPA02009116A patent/MXPA02009116A/es active IP Right Grant
- 2001-03-16 IL IL15151201A patent/IL151512A0/xx not_active IP Right Cessation
- 2001-03-16 EA EA200201000A patent/EA005592B1/ru not_active IP Right Cessation
- 2001-03-16 AU AU5003401A patent/AU5003401A/xx active Pending
- 2001-03-16 HU HU0302093A patent/HUP0302093A3/hu unknown
- 2001-03-16 SK SK1348-2002A patent/SK286169B6/sk not_active IP Right Cessation
- 2001-03-16 HR HR20020837A patent/HRP20020837B1/xx not_active IP Right Cessation
- 2001-03-16 HK HK03101651.5A patent/HK1049449B/en not_active IP Right Cessation
- 2001-03-16 CN CNB018068235A patent/CN1239160C/zh not_active Expired - Fee Related
- 2001-03-16 BR BR0109334-7A patent/BR0109334A/pt not_active Application Discontinuation
- 2001-03-16 CZ CZ20023162A patent/CZ20023162A3/cs unknown
- 2001-03-16 EP EP01923331A patent/EP1265616B1/en not_active Expired - Lifetime
- 2001-03-16 EE EEP200200535A patent/EE05129B1/xx not_active IP Right Cessation
- 2001-03-16 PT PT01923331T patent/PT1265616E/pt unknown
- 2001-03-16 AU AU2001250034A patent/AU2001250034B2/en not_active Ceased
- 2001-03-16 WO PCT/US2001/040302 patent/WO2001070208A2/en not_active Ceased
- 2001-03-16 DE DE60119703T patent/DE60119703T2/de not_active Expired - Lifetime
- 2001-03-16 NZ NZ521171A patent/NZ521171A/en not_active IP Right Cessation
- 2001-03-16 AT AT01923331T patent/ATE326227T1/de active
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- 2001-03-16 CA CA002402983A patent/CA2402983A1/en not_active Abandoned
- 2001-03-16 ES ES01923331T patent/ES2261393T3/es not_active Expired - Lifetime
- 2001-03-16 KR KR1020027012420A patent/KR100805648B1/ko not_active Expired - Fee Related
- 2001-03-16 DK DK01923331T patent/DK1265616T3/da active
- 2001-03-16 JP JP2001568406A patent/JP2003527416A/ja active Pending
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2002
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2006
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2007
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