AR039317A1 - Proceso para la preparacion de una suspension esteril de particulas de dipropionato de beclometasona para administracion por inhalacion - Google Patents
Proceso para la preparacion de una suspension esteril de particulas de dipropionato de beclometasona para administracion por inhalacionInfo
- Publication number
- AR039317A1 AR039317A1 ARP030101350A ARP030101350A AR039317A1 AR 039317 A1 AR039317 A1 AR 039317A1 AR P030101350 A ARP030101350 A AR P030101350A AR P030101350 A ARP030101350 A AR P030101350A AR 039317 A1 AR039317 A1 AR 039317A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- suspension
- sterile
- inhalation administration
- sterile suspension
- Prior art date
Links
- 239000000725 suspension Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- KUVIULQEHSCUHY-XYWKZLDCSA-N Beclometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)COC(=O)CC)(OC(=O)CC)[C@@]1(C)C[C@@H]2O KUVIULQEHSCUHY-XYWKZLDCSA-N 0.000 title 1
- 229950000210 beclometasone dipropionate Drugs 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 4
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000002663 nebulization Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Abstract
Uso de un turboemulsificador, comenzando a partir de un ingrediente activo estéril micronizado. Reivindicación 1: Un proceso para la preparación de suspensiones útil para preparar formulaciones farmacéuticas para inhalación por nebulización, caracterizado porque comprende los siguientes pasos: a) agregar uno o más ingredientes activos, bajo la forma de un polvo estéril micronizado, a una solución acuosa que constituye el vehículo, en un turboemulsificador equipado con una turbina de alto poder y conectado a una tolva de carga, introduciendo dichos ingredientes activos a través de la turbina después de aplicar vacío; b) homogeneizar el ingrediente activo en la suspensión, aún al vacío, usando el sistema de turbina; c) distribuir la suspensión obtenida de este modo en recipientes adecuados, tales como recipientes para dosis individuales.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002MI000808A ITMI20020808A1 (it) | 2002-04-17 | 2002-04-17 | Procedimento per la preparazione di una sospensione sterile di particelle di beclometasone dipropionato da somministrare per inalazione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR039317A1 true AR039317A1 (es) | 2005-02-16 |
Family
ID=11449718
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030101350A AR039317A1 (es) | 2002-04-17 | 2003-04-16 | Proceso para la preparacion de una suspension esteril de particulas de dipropionato de beclometasona para administracion por inhalacion |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7541021B2 (es) |
| EP (1) | EP1494647B1 (es) |
| CN (1) | CN1292733C (es) |
| AR (1) | AR039317A1 (es) |
| AT (1) | ATE338539T1 (es) |
| AU (1) | AU2003227627A1 (es) |
| BR (1) | BRPI0304821B8 (es) |
| CA (1) | CA2481520C (es) |
| CY (1) | CY1105800T1 (es) |
| DE (1) | DE60308164T2 (es) |
| DK (1) | DK1494647T3 (es) |
| EA (1) | EA007629B1 (es) |
| ES (1) | ES2272987T3 (es) |
| HK (1) | HK1079986B (es) |
| HR (1) | HRP20040964A2 (es) |
| IT (1) | ITMI20020808A1 (es) |
| MA (1) | MA27194A1 (es) |
| MX (1) | MXPA04010117A (es) |
| PE (1) | PE20030948A1 (es) |
| PL (1) | PL207863B1 (es) |
| PT (1) | PT1494647E (es) |
| SI (1) | SI1494647T1 (es) |
| UA (1) | UA79453C2 (es) |
| WO (1) | WO2003086347A1 (es) |
| ZA (1) | ZA200408319B (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7879833B2 (en) * | 2002-12-12 | 2011-02-01 | Nycomed Gmbh | Combination medicament |
| WO2005025578A1 (en) * | 2003-09-16 | 2005-03-24 | Altana Pharma Ag | Use of ciclesonide for the treatment of respiratory diseases |
| PL1675573T4 (pl) | 2003-10-23 | 2016-04-29 | Otsuka Pharma Co Ltd | Sterylny preparat do wstrzykiwań arypiprazolu o kontrolowanym uwalnianiu i sposób |
| PE20050941A1 (es) * | 2003-12-16 | 2005-11-08 | Nycomed Gmbh | Suspensiones acuosas de ciclesonida para nebulizacion |
| US20070020298A1 (en) * | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid |
| US20070020299A1 (en) * | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
| CA2563556C (en) * | 2004-04-20 | 2013-01-29 | Altana Pharma Ag | Use of ciclesonide for the treatment of respiratory diseases in a smoking patient |
| GB0425266D0 (en) | 2004-11-16 | 2004-12-15 | Norton Healthcare Ltd | Pharmaceutical manufacturing process |
| ES2388287T3 (es) | 2005-01-20 | 2012-10-11 | Eratech S.R.L. | Procedimiento para la preparación de suspensiones concentradas de fármacos y kit correspondiente |
| JP2009508859A (ja) * | 2005-09-15 | 2009-03-05 | エラン ファーマ インターナショナル リミテッド | ナノ粒子アリピプラゾール製剤 |
| US20070099883A1 (en) * | 2005-10-07 | 2007-05-03 | Cheryl Lynn Calis | Anhydrous mometasone furoate formulation |
| JP2009526860A (ja) * | 2006-02-15 | 2009-07-23 | ティカ レーケメデル アーベー | 安定したコルチコステロイド混合物 |
| DK2170348T3 (en) * | 2007-06-22 | 2016-11-07 | Dompé Farm S P A | SHOWER TABLETS for inhalation |
| US12370352B2 (en) | 2007-06-28 | 2025-07-29 | Cydex Pharmaceuticals, Inc. | Nasal and ophthalmic delivery of aqueous corticosteroid solutions |
| NO2170279T3 (es) * | 2007-07-31 | 2018-05-26 | ||
| CN102475708A (zh) * | 2010-11-23 | 2012-05-30 | 天津金耀集团有限公司 | 丙酸氟替卡松和含辅料的水构成的治疗皮肤病的分离式水混悬剂药物 |
| CN102657659A (zh) * | 2010-11-23 | 2012-09-12 | 天津金耀集团有限公司 | 皮肤用含有辅料的丙酸氟替卡松与含有辅料的水的透皮吸收药物 |
| CN103501791B (zh) | 2011-05-03 | 2016-05-18 | 奇斯药制品公司 | 用于通过吸入给药的改良皮质类固醇悬浮制剂 |
| CN103505412A (zh) * | 2012-06-26 | 2014-01-15 | 上海臣邦医药科技有限公司 | 一种吸入用丙酸氟替卡松混悬液的制备方法 |
| WO2022098321A1 (en) * | 2020-11-09 | 2022-05-12 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Process for the preparation of sterilised suspensions for the administration by inhalation |
| WO2022231531A1 (en) * | 2021-04-29 | 2022-11-03 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Process for the preparation of sterilized suspensions for the inhalation by nebulization |
| WO2022231533A1 (en) * | 2021-04-29 | 2022-11-03 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Process for the preparation of sterilized suspensions for the inhalation by nebulization |
| WO2023022672A2 (en) * | 2021-08-18 | 2023-02-23 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Process for the preparation of homogeneous suspensions for the inhalation by nebulization |
| WO2024180569A1 (en) * | 2023-03-01 | 2024-09-06 | Ajaykumar Balraj Kanduri | A synergistic aqueous nebulization suspension for management of infectious respiratory disorders and process of preparation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1303692B1 (it) * | 1998-11-03 | 2001-02-23 | Chiesi Farma Spa | Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione. |
| ITMI20022674A1 (it) * | 2002-12-18 | 2004-06-19 | Chiesi Farma Spa | Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione. |
-
2002
- 2002-04-17 IT IT2002MI000808A patent/ITMI20020808A1/it unknown
-
2003
- 2003-04-15 ES ES03725033T patent/ES2272987T3/es not_active Expired - Lifetime
- 2003-04-15 HR HR20040964A patent/HRP20040964A2/hr not_active Application Discontinuation
- 2003-04-15 SI SI200330532T patent/SI1494647T1/sl unknown
- 2003-04-15 HK HK06100045.9A patent/HK1079986B/zh not_active IP Right Cessation
- 2003-04-15 UA UA20041008327A patent/UA79453C2/uk unknown
- 2003-04-15 CA CA2481520A patent/CA2481520C/en not_active Expired - Fee Related
- 2003-04-15 WO PCT/EP2003/003916 patent/WO2003086347A1/en not_active Ceased
- 2003-04-15 DK DK03725033T patent/DK1494647T3/da active
- 2003-04-15 PL PL373331A patent/PL207863B1/pl unknown
- 2003-04-15 AT AT03725033T patent/ATE338539T1/de active
- 2003-04-15 DE DE60308164T patent/DE60308164T2/de not_active Expired - Lifetime
- 2003-04-15 PT PT03725033T patent/PT1494647E/pt unknown
- 2003-04-15 EA EA200401209A patent/EA007629B1/ru unknown
- 2003-04-15 AU AU2003227627A patent/AU2003227627A1/en not_active Abandoned
- 2003-04-15 US US10/510,232 patent/US7541021B2/en not_active Expired - Fee Related
- 2003-04-15 EP EP03725033A patent/EP1494647B1/en not_active Expired - Lifetime
- 2003-04-15 BR BRPI0304821A patent/BRPI0304821B8/pt not_active IP Right Cessation
- 2003-04-15 CN CNB038111608A patent/CN1292733C/zh not_active Expired - Lifetime
- 2003-04-15 MX MXPA04010117A patent/MXPA04010117A/es active IP Right Grant
- 2003-04-16 AR ARP030101350A patent/AR039317A1/es unknown
- 2003-04-16 PE PE2003000389A patent/PE20030948A1/es not_active Application Discontinuation
-
2004
- 2004-10-08 MA MA27897A patent/MA27194A1/fr unknown
- 2004-10-14 ZA ZA200408319A patent/ZA200408319B/xx unknown
-
2006
- 2006-11-21 CY CY20061101689T patent/CY1105800T1/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |