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AR037629A1 - Formulaciones farmaceuticas que comprenden un derivado de platino - Google Patents

Formulaciones farmaceuticas que comprenden un derivado de platino

Info

Publication number
AR037629A1
AR037629A1 ARP020104679A ARP020104679A AR037629A1 AR 037629 A1 AR037629 A1 AR 037629A1 AR P020104679 A ARP020104679 A AR P020104679A AR P020104679 A ARP020104679 A AR P020104679A AR 037629 A1 AR037629 A1 AR 037629A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical formulations
platinum derivative
pharmaceutically acceptable
formulations
platinum
Prior art date
Application number
ARP020104679A
Other languages
English (en)
Inventor
Sara Lauria
Alessandro Martini
Cristina Ciocca
Original Assignee
Pharmacia Italia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21744006&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR037629(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa
Publication of AR037629A1 publication Critical patent/AR037629A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Nuevas formulaciones de solución estables que comprenden oxaliplatino, una cantidad estabilizante efectiva de ácido láctico y/o una sal farmacéuticamente aceptable del mismo, y un vehículo farmacéuticamente aceptable. Un método para elaborar dichas formulaciones listas para administración y su uso, en la terapia anti-tumoral.
ARP020104679A 2001-12-06 2002-12-04 Formulaciones farmaceuticas que comprenden un derivado de platino AR037629A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/010,122 US6476068B1 (en) 2001-12-06 2001-12-06 Platinum derivative pharmaceutical formulations

Publications (1)

Publication Number Publication Date
AR037629A1 true AR037629A1 (es) 2004-11-17

Family

ID=21744006

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020104679A AR037629A1 (es) 2001-12-06 2002-12-04 Formulaciones farmaceuticas que comprenden un derivado de platino

Country Status (41)

Country Link
US (3) US6476068B1 (es)
EP (1) EP1453517B1 (es)
JP (1) JP2005515202A (es)
KR (1) KR100941210B1 (es)
CN (1) CN100540006C (es)
AP (1) AP1760A (es)
AR (1) AR037629A1 (es)
AT (1) ATE317260T1 (es)
AU (1) AU2002352105B2 (es)
BR (1) BR0214757A (es)
CA (1) CA2468916C (es)
CO (1) CO5580776A2 (es)
CR (1) CR7362A (es)
CY (1) CY1105608T1 (es)
DE (1) DE60209145T2 (es)
DK (1) DK1453517T3 (es)
EA (1) EA008090B1 (es)
EC (1) ECSP045140A (es)
ES (1) ES2258661T3 (es)
GE (1) GEP20063895B (es)
HR (1) HRP20040514A2 (es)
HU (1) HUP0402217A3 (es)
IL (2) IL162348A0 (es)
IS (1) IS2580B (es)
MA (1) MA27153A1 (es)
ME (1) MEP10408A (es)
MX (1) MXPA04005423A (es)
MY (1) MY134422A (es)
NO (1) NO330159B1 (es)
NZ (1) NZ533383A (es)
OA (1) OA12739A (es)
PL (1) PL206755B1 (es)
PT (1) PT1453517E (es)
RO (1) RO121509B1 (es)
RS (1) RS50360B (es)
SI (1) SI21493A (es)
TN (1) TNSN04104A1 (es)
TW (1) TW200409640A (es)
UA (1) UA77728C2 (es)
WO (1) WO2003047587A1 (es)
ZA (1) ZA200404525B (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004505A1 (en) * 2001-07-02 2003-01-16 Debiopharm S.A. Oxaliplatin active substance with a very low content of oxalic acid
CA2388352A1 (en) * 2002-05-31 2003-11-30 Voiceage Corporation A method and device for frequency-selective pitch enhancement of synthesized speed
US20040022842A1 (en) * 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
DE10314377A1 (de) * 2003-03-28 2004-10-07 Stada Arzneimittel Ag Gebrauchsfertige Oxaliplatin-Lösungen
GB2441445B (en) * 2003-08-28 2008-04-23 Mayne Pharma Ltd Acid containing oxaliplatin formulation
WO2005020980A1 (en) * 2003-08-28 2005-03-10 Mayne Pharma Pty Ltd Acid containing oxaliplatin formulations
AU2004288709B2 (en) * 2003-11-07 2011-01-06 Novartis Vaccines And Diagnostics, Inc. Methods for synthesizing quinolinone compounds
RU2273475C2 (ru) * 2004-04-06 2006-04-10 Государственное учреждение системы высшего и послевузовского профессионального образования "Сибирский государственный медицинский университет" (ГУ СВ ПО СибГМУ) Способ лечения диссеминированного колоректального рака
US7795205B2 (en) * 2004-04-12 2010-09-14 Canyon Pharmaceuticals, Inc. Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor
CN103054871A (zh) * 2004-06-09 2013-04-24 大鹏药品工业株式会社 抗肿瘤效果增强剂、抗肿瘤剂和癌治疗方法
MX2007000414A (es) * 2004-07-12 2007-06-15 Sicor Inc Complejo de cis-diyodo-(trans-1,2-ciclohexanodiamina) platino (ii) y procesos para preparar oxaliplatina de alta pureza.
US20060063833A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Ready-to-use oxaliplatin solutions
US20060063720A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Oxaliplatin solution concentrate
DE102004052877B4 (de) * 2004-11-02 2008-06-19 Ebewe Pharma Ges.M.B.H. Nfg.Kg Stabile wässrige Formulierungen eines Platin-Derivats
CN1311818C (zh) * 2004-11-22 2007-04-25 山东蓝金生物工程有限公司 一种抗实体肿瘤的药物组合物
DE102004063764A1 (de) * 2004-12-29 2006-07-13 Hexal Ag Kunststoff-Flasche für Oxaliplatin
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
WO2006103691A1 (en) * 2005-03-28 2006-10-05 Dabur Pharma Ltd. Stable pharmaceutical compositions of platinum (ii) antitumour agents
RU2426539C2 (ru) * 2005-05-13 2011-08-20 Новартис Аг Способы лечения устойчивого к лекарственным средствам рака
DE102005038347A1 (de) * 2005-08-11 2007-02-15 Hexal Ag Herstellung einer Oxaliplatin-Lösung und Behälter sowie Behälter-Set mit der Lösung
WO2007029268A2 (en) * 2005-09-05 2007-03-15 Dabur Pharma Limited Stable oxaliplatin formulation
CA2627544C (en) * 2005-11-29 2015-07-07 Novartis Ag Formulations of quinolinones for the treatment of cancer
US20090076139A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched oxalplatin
US20100267824A1 (en) * 2007-11-12 2010-10-21 Intas Pharmaceuticals Limited Stable oxaliplatin composition for parenteral administration
CA2715832A1 (en) * 2008-02-29 2009-09-11 Eagle Pharmaceuticals, Inc. Topotecan ready to use solutions
US9023834B2 (en) * 2008-11-13 2015-05-05 Taigen Biotechnology Co., Ltd. Lyophilization formulation
WO2011034394A2 (ko) 2009-09-21 2011-03-24 주식회사 중외제약 옥살리플라틴의 나노 입자 및 이를 제조하는 방법
US9387152B2 (en) 2010-06-28 2016-07-12 The General Hospital Corporation Blood substitutes and uses thereof
CN102274171A (zh) * 2011-08-04 2011-12-14 上海希迪制药有限公司 一种奥沙利铂注射剂
MX363455B (es) 2012-07-18 2019-03-25 Onyx Therapeutics Inc Composiciones liposómicas de inhibidores de proteasoma basadas en epoxicetona.
JP5929607B2 (ja) * 2012-08-06 2016-06-08 ニプロ株式会社 オキサリプラチン製剤
CN102885765B (zh) * 2012-10-25 2013-11-06 哈药集团生物工程有限公司 一种盐酸伊立替康注射液及其制备方法
US10098813B2 (en) * 2014-09-03 2018-10-16 Sun Pharmaceutical Industries Limited Perfusion dosage form
KR101683635B1 (ko) * 2014-12-29 2016-12-09 가천대학교 산학협력단 락테이트 금속염을 포함하는 암 치료용 약학 조성물
ES3007633T3 (en) * 2015-02-13 2025-03-20 Sun Pharmaceutical Ind Ltd Intravenous infusion dosage form comprising pemetrexed
KR102293907B1 (ko) * 2015-06-30 2021-08-26 한미약품 주식회사 이리노테칸 함유 경구용 고형제제 및 그 제조방법
ES2968415T3 (es) 2016-02-09 2024-05-09 Sun Pharmaceutical Ind Ltd Sistema de perfusión
CN109996809A (zh) 2016-11-14 2019-07-09 诺华股份有限公司 与促融合蛋白minion相关的组合物、方法和治疗用途
JP7290870B2 (ja) 2018-01-12 2023-06-14 メティメディ ファーマシューティカルズ カンパニー リミテッド 慢性炎症性疾患を処置する方法
KR101998246B1 (ko) 2018-08-22 2019-07-10 주식회사 메타파인즈 금속이온에 결합된 이온화합물을 포함하는 암 치료용 약학 조성물

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041077B2 (ja) 1976-09-06 1985-09-13 喜徳 喜谷 1,2‐ジアミノシクロヘキサン異性体のシス白金(2)錯体
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
DE69233169T2 (de) 1991-11-15 2004-05-27 Smithkline Beecham Corp. Cisplatin und Topotecan enthaltende Zusammensetzung als antitumor.
JPH0776230B2 (ja) 1992-01-13 1995-08-16 田中貴金属工業株式会社 白金化合物の製造方法
JP2673331B2 (ja) 1993-01-12 1997-11-05 田中貴金属工業 株式会社 光学的に高純度なシス―オキザラート(トランス―1―1,2―シクロヘキサンジアミン)白金(▲ii▼)
JPH06287021A (ja) 1992-04-22 1994-10-11 Tanaka Kikinzoku Kogyo Kk 光学活性な白金錯化合物の光学的分割方法
AU5416394A (en) 1992-11-24 1994-06-22 Debiopharm S.A. Cisplatinum/oxaliplatinum combination
DK0835657T3 (da) * 1992-11-27 2005-01-10 Mayne Pharma Usa Inc Stabil, injicerbar paclitaxelsammensætning
JP3025602B2 (ja) 1993-05-21 2000-03-27 デビオファーム エス.アー. 光学的に高純度なシス−オキザラート(トランス−l−1,2−シクロヘキサンジアミン)白金(II)錯体の製造方法
US5455270A (en) * 1993-08-11 1995-10-03 Bristol-Myers Squibb Co. Stabilized solutions of platinum(II) antitumor agents
ATE197249T1 (de) 1994-08-08 2000-11-15 Debiopharm Sa Stabiles arzneimittel enthaltend oxaliplatin
EP0715854B1 (en) 1994-11-11 2003-09-10 Debiopharm S.A. Carcinostatic compositions containing cis-oxaliplatinum and one or more other compatible carcinostatic substances
US5919816A (en) 1994-11-14 1999-07-06 Bionumerik Pharmaceuticals, Inc. Formulations and methods of reducing toxicity of antineoplastic agents
EP0812852B1 (en) * 1995-02-28 2003-04-23 Yoshinori Kidani Novel platinum (iv) complexes, process for producing the same, and carcinostatic agents containing the same
US5776959A (en) 1995-06-05 1998-07-07 Washington University Anticonvulsant and anxiolytic lactam and thiolactam derivatives
JP3154399B2 (ja) 1996-07-04 2001-04-09 デビオファーム エス.アー. 白金化合物の製造方法
EP0897389B1 (fr) * 1996-03-11 2002-07-03 Yoshinori Kidani Complexes de platine dinucleaires, procede pour leur preparation et compositions pharmaceutiques en contenant
PT929293E (pt) 1996-08-23 2004-03-31 Sequus Pharm Inc Lipossomas contendo um composto de cisplatina
US6056973A (en) 1996-10-11 2000-05-02 Sequus Pharmaceuticals, Inc. Therapeutic liposome composition and method of preparation
UA71540C2 (uk) 1997-02-05 2004-12-15 Фармація Енд Апджон Компані Спосіб одержання ліпідних комплексів або ліпосом водонерозчинного діаміноциклогексанкарбоксилату платини та фармацевтична композиція, що містить ліпідний комплекс або ліпосоми водонерозчинного діаміноциклогексанкарбоксилату платини
EP1014990B1 (en) 1997-03-07 2006-09-06 Sanofi-Aventis U.S. LLC Antitumor combination of 3-amino-1,2,4-benzotriazine 1,4-dioxide/paclitaxel/platinum
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
GB9804013D0 (en) * 1998-02-25 1998-04-22 Sanofi Sa Formulations
US6866857B1 (en) 1998-10-14 2005-03-15 Debiopharm S.A. Oxalipatinum preparation packaging
BRPI0013613B8 (pt) 1999-08-30 2021-05-25 Debiopharm Sa composição farmacêuticamente estável de oxaliplatina para administração parenteral.
AU2001240001A1 (en) 2000-03-08 2001-09-17 Bristol-Myers Squibb Company Oral dosage form for administration of the combination of tegafur, uracil, folinic acid, and oxaliplatin and method of using the same
SE0003026D0 (sv) * 2000-08-25 2000-08-25 Kerstin Sunnerheim Use for conifer sapling protection

Also Published As

Publication number Publication date
TW200409640A (en) 2004-06-16
AU2002352105A1 (en) 2003-06-17
IS7298A (is) 2004-06-03
NO20042842L (no) 2004-07-05
GEP20063895B (en) 2006-08-10
HK1072002A1 (zh) 2005-08-12
ZA200404525B (en) 2005-08-15
BR0214757A (pt) 2004-09-14
US6476068B1 (en) 2002-11-05
TNSN04104A1 (fr) 2006-06-01
PT1453517E (pt) 2006-06-30
DK1453517T3 (da) 2006-06-19
PL370254A1 (en) 2005-05-16
JP2005515202A (ja) 2005-05-26
MY134422A (en) 2007-12-31
US20030109515A1 (en) 2003-06-12
EA008090B1 (ru) 2007-02-27
DE60209145D1 (de) 2006-04-20
CN100540006C (zh) 2009-09-16
CA2468916C (en) 2009-01-20
CO5580776A2 (es) 2005-11-30
ATE317260T1 (de) 2006-02-15
KR100941210B1 (ko) 2010-02-10
RS50360B (sr) 2009-11-10
KR20050058278A (ko) 2005-06-16
IS2580B (is) 2010-02-15
ECSP045140A (es) 2004-08-27
EA200400777A1 (ru) 2004-12-30
CY1105608T1 (el) 2010-12-22
RO121509B1 (ro) 2007-10-30
SI21493A (sl) 2004-12-31
US20030109514A1 (en) 2003-06-12
YU59704A (sh) 2006-08-17
HUP0402217A3 (en) 2005-11-28
WO2003047587A1 (en) 2003-06-12
OA12739A (en) 2006-06-30
AP2004003055A0 (en) 2004-06-30
MEP10408A (en) 2011-02-10
AU2002352105B2 (en) 2009-12-03
IL162348A (en) 2010-11-30
CA2468916A1 (en) 2003-06-12
NZ533383A (en) 2007-02-23
DE60209145T2 (de) 2006-10-26
UA77728C2 (en) 2007-01-15
US6673805B2 (en) 2004-01-06
HUP0402217A2 (hu) 2005-01-28
ES2258661T3 (es) 2006-09-01
CR7362A (es) 2009-02-12
HRP20040514A2 (en) 2004-10-31
EP1453517B1 (en) 2006-02-08
IL162348A0 (en) 2005-11-20
CN1612737A (zh) 2005-05-04
MA27153A1 (fr) 2005-01-03
MXPA04005423A (es) 2004-10-11
AP1760A (en) 2007-07-18
PL206755B1 (pl) 2010-09-30
EP1453517A1 (en) 2004-09-08
NO330159B1 (no) 2011-02-28

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