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MX2013012975A - Composiciones farmaceuticas. - Google Patents

Composiciones farmaceuticas.

Info

Publication number
MX2013012975A
MX2013012975A MX2013012975A MX2013012975A MX2013012975A MX 2013012975 A MX2013012975 A MX 2013012975A MX 2013012975 A MX2013012975 A MX 2013012975A MX 2013012975 A MX2013012975 A MX 2013012975A MX 2013012975 A MX2013012975 A MX 2013012975A
Authority
MX
Mexico
Prior art keywords
pharmaceutical compositions
pharmaceutical solution
ethanol
propellant
drug
Prior art date
Application number
MX2013012975A
Other languages
English (en)
Other versions
MX340924B (es
Inventor
Stuart Corr
Timothy James Noakes
Original Assignee
Mexichem Amanco Holding Sa De Capital Variable
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mexichem Amanco Holding Sa De Capital Variable filed Critical Mexichem Amanco Holding Sa De Capital Variable
Publication of MX2013012975A publication Critical patent/MX2013012975A/es
Publication of MX340924B publication Critical patent/MX340924B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a una solución farmacéutica para un aparato de suministro de la medicación, especialmente un inhalador de dosis medida. La solución farmacéutica comprende: (a) un componente propulsor licuado que consiste esencialmente de, y que consiste completamente de manera preferible de 1,1-difluoroetano (R-152a); (b) etanol; y (c) un componente farmacéutico disuelto en la mezcla del propulsor/etanol que consiste de al menos un fármaco seleccionado del grupo que consiste de dipropionato de beclometasona (BDP) y propionato de fluticasona (FP).
MX2013012975A 2011-05-13 2012-05-11 Composiciones farmaceuticas. MX340924B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1108039.7A GB201108039D0 (en) 2011-05-13 2011-05-13 Compositions
PCT/GB2012/051059 WO2012156711A1 (en) 2011-05-13 2012-05-11 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
MX2013012975A true MX2013012975A (es) 2013-12-12
MX340924B MX340924B (es) 2016-08-01

Family

ID=44260493

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013012975A MX340924B (es) 2011-05-13 2012-05-11 Composiciones farmaceuticas.

Country Status (12)

Country Link
US (4) US20140234229A1 (es)
EP (1) EP2706987B8 (es)
JP (2) JP5904613B2 (es)
CN (2) CN103517706A (es)
AU (1) AU2012257546C1 (es)
BR (1) BR112013029202B1 (es)
CA (1) CA2835810C (es)
ES (1) ES2541417T3 (es)
GB (1) GB201108039D0 (es)
MX (1) MX340924B (es)
WO (1) WO2012156711A1 (es)
ZA (1) ZA201308208B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201108039D0 (en) * 2011-05-13 2011-06-29 Mexichem Amanco Holding Sa Compositions
GB201306984D0 (en) 2013-04-17 2013-05-29 Mexichem Amanco Holding Sa Composition
GB2545025A (en) * 2015-12-04 2017-06-07 Mexichem Fluor Sa De Cv Pharmaceutical composition
GB2554092A (en) * 2016-09-19 2018-03-28 Mexichem Fluor Sa De Cv Pharmaceutical composition
EP3383366B2 (en) * 2015-12-04 2024-06-05 Mexichem Fluor S.A. de C.V. Pharmaceutical composition
CN105476961B (zh) * 2015-12-16 2019-01-04 武汉同济现代医药科技股份有限公司 一种丙酸倍氯米松气雾剂及其制备方法
US11260052B2 (en) * 2016-09-19 2022-03-01 Mexichem Fluor S.A. De C.V. Pharmaceutical composition
GB2558191A (en) * 2016-09-19 2018-07-11 Mexichem Fluor Sa De Cv Pharmaceutical composition
GB2554088A (en) * 2016-09-19 2018-03-28 Mexichem Fluor Sa De Cv Pharmaceautical composition
CN113069417A (zh) * 2016-09-19 2021-07-06 墨西哥氟石股份公司 药物组合物
GB201620519D0 (en) * 2016-12-02 2017-01-18 Mexichem Fluor Sa De Cv Pharmaceutical composition
PE20191043A1 (es) 2016-09-19 2019-08-06 Mexichem Fluor Sa De Cv Composicion farmaceutica
US20190374519A1 (en) * 2016-09-19 2019-12-12 Mexichem Fluor S.A. De C.V. Pharmaceutical composition
JP6781828B2 (ja) 2016-09-19 2020-11-04 メキシケム フロー エセ・ア・デ・セ・ヴェ 医薬組成物
GB2554091A (en) * 2016-09-19 2018-03-28 Mexichem Fluor Sa De Cv Pharmaceutical composition
US11521518B1 (en) 2017-05-04 2022-12-06 IngMar Medical, Ltd. Airway simulation system
GB201712159D0 (en) * 2017-07-28 2017-09-13 Mexichem Fluor Sa De Cv Pharmaceutical composition
EP3801479A1 (en) * 2018-06-07 2021-04-14 Kindeva Drug Delivery L.P. Fluticasone and vilanterol formulation and inhaler
GB2584686A (en) 2019-06-11 2020-12-16 Mexichem Fluor Sa De Cv Methods
PE20221867A1 (es) 2020-01-28 2022-12-02 Chiesi Farm Spa Inhaladores de dosis medida presurizada que comprenden una formulacion farmaceutica amortiguada
AU2021223587A1 (en) 2020-02-20 2022-09-29 Chiesi Farmaceutici S.P.A. Pressurised metered dose inhalers comprising a buffered pharmaceutical formulation
AU2024212659A1 (en) * 2023-01-24 2025-08-07 Cipla Limited Pharmaceutical compositions of green propellant

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8828477D0 (en) 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US5439670A (en) 1989-11-28 1995-08-08 Riker Laboratories, Inc. Medicinal aerosol formulations
IL97065A (en) 1990-02-02 1994-01-25 Fisons Plc Repellent preparations for aerosol
DE4003272A1 (de) 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen
MX9203481A (es) * 1990-10-18 1992-07-01 Minnesota Mining & Mfg Formulaciones.
US7105152B1 (en) 1991-12-18 2006-09-12 3M Innovative Properties Company Suspension aerosol formulations
CN1088580C (zh) * 1994-12-22 2002-08-07 阿斯特拉公司 气溶胶药物制剂
ES2276736T3 (es) * 1995-04-14 2007-07-01 Smithkline Beecham Corporation Inhalador medidor de dosis para propionato de flucticasona.
JP2001511160A (ja) * 1997-02-05 2001-08-07 ヤゴ リサーチ アクチェンゲゼルシャフト 医学用エアゾール配合物
KR100589926B1 (ko) * 1997-09-29 2006-06-15 넥타르 테라퓨틱스 천공된 미립자 및 사용 방법
US6103266A (en) 1998-04-22 2000-08-15 Tapolsky; Gilles H. Pharmaceutical gel preparation applicable to mucosal surfaces and body tissues
US6451285B2 (en) 1998-06-19 2002-09-17 Baker Norton Pharmaceuticals, Inc. Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
DK1102579T3 (da) 1998-08-04 2003-07-14 Jago Res Ag Medicinske aerosolformuleringer
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
GB2392164B (en) * 1999-09-11 2004-04-07 Glaxo Group Ltd Pharmaceutical formulation of fluticasone propionate
IT1317904B1 (it) * 1999-09-11 2003-07-15 Glaxo Group Ltd Formulazione farmaceutica di propionato di fluticasone.
US6432415B1 (en) * 1999-12-17 2002-08-13 Axrix Laboratories, Inc. Pharmaceutical gel and aerosol formulations and methods to administer the same to skin and mucosal surfaces
CN1144582C (zh) 2000-11-28 2004-04-07 中国药科大学 治疗呼吸系统疾病的无氟里昂药用气雾剂
GB2389530B (en) * 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
GB0323684D0 (en) * 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
GB0323685D0 (en) 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
US20060018840A1 (en) 2004-06-28 2006-01-26 Nektar Therapeutics Aerosolizable formulation comprising nicotine
WO2007020204A2 (en) 2005-08-12 2007-02-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Hfc solution formulations for inhalation containing salbutamol hydrochloride or salbutamol citrate
GB0915106D0 (en) 2009-08-28 2009-10-07 Glaxo Group Ltd Process
WO2012093252A1 (en) 2011-01-06 2012-07-12 Cipla Limited Pharmaceutical composition
GB201108039D0 (en) * 2011-05-13 2011-06-29 Mexichem Amanco Holding Sa Compositions

Also Published As

Publication number Publication date
ES2541417T3 (es) 2015-07-20
WO2012156711A1 (en) 2012-11-22
US10258569B2 (en) 2019-04-16
CN107252415B (zh) 2020-08-11
JP6125679B2 (ja) 2017-05-10
US20140234229A1 (en) 2014-08-21
US10668018B2 (en) 2020-06-02
BR112013029202B1 (pt) 2022-04-12
AU2012257546A1 (en) 2013-11-28
GB201108039D0 (en) 2011-06-29
BR112013029202A2 (pt) 2017-02-14
JP2016138107A (ja) 2016-08-04
JP2014513146A (ja) 2014-05-29
CA2835810C (en) 2016-08-09
EP2706987A1 (en) 2014-03-19
EP2706987B1 (en) 2015-04-08
AU2012257546C1 (en) 2015-12-24
US20190142750A1 (en) 2019-05-16
AU2012257546B2 (en) 2015-06-18
JP5904613B2 (ja) 2016-04-13
ZA201308208B (en) 2014-06-25
CA2835810A1 (en) 2012-11-22
MX340924B (es) 2016-08-01
US10258568B2 (en) 2019-04-16
CN103517706A (zh) 2014-01-15
US20170027867A1 (en) 2017-02-02
EP2706987B8 (en) 2015-05-27
US20170007701A1 (en) 2017-01-12
CN107252415A (zh) 2017-10-17

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