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AR023703A1 - N-carboniloximetilesteres de nitroetilendiaminas y nitroguanidinas, proceso para su preparacion, composicion parasiticida, una preparacion en combinacionpara controlar parasitos en animales de sangre caliente, uso de dichos compuestos y compuestos intermediarios para su uso en dicho proceso de prepa - Google Patents

N-carboniloximetilesteres de nitroetilendiaminas y nitroguanidinas, proceso para su preparacion, composicion parasiticida, una preparacion en combinacionpara controlar parasitos en animales de sangre caliente, uso de dichos compuestos y compuestos intermediarios para su uso en dicho proceso de prepa

Info

Publication number
AR023703A1
AR023703A1 ARP990105795A ARP990105795A AR023703A1 AR 023703 A1 AR023703 A1 AR 023703A1 AR P990105795 A ARP990105795 A AR P990105795A AR P990105795 A ARP990105795 A AR P990105795A AR 023703 A1 AR023703 A1 AR 023703A1
Authority
AR
Argentina
Prior art keywords
alkyl
substituted
preparation
thioalkyl
haloalkyl
Prior art date
Application number
ARP990105795A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR023703A1 publication Critical patent/AR023703A1/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/12Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/16Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof the nitrogen atom being part of a heterocyclic ring
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44Guanidine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

N-carboxiloximetilesteres de nitroetilendiaminas y nitroguanidinas, que tiene la formula (1) en donde R1 es hidrogeno o un radical del grupo alquiloC1-4, formilo, alquilo C1-6-carbonilo, alquilo C1-4-sulfonilo, arilo, arilsulfonilo, arilcarbonilo, heterociclilo, y alquilo C1-6 sustituido por heterociclilo,cuyo radical está insaturado o mono - poli-sustituido por sustituyentes idénticos o diferentes; siendo estos sustituyentes alquilo C1-4, alcoxilo C1-4,tioalquilo C1-4, haloalquilo C1-4, halogeno, hidroxilo, ciano, nitro, amino, alquilo C1-4-amino, (alquilo C1-4)2-amino, alcoxicarbonilo, alquilo C1-4-sulfoniloy arilsulfonilo; X es CH o N; Y es un radical de retiro de electrones; T tiene los significados de R1, o junto con U forma un puentede alquileno C1-4 que estáinsustituido o sustituido por un radical R1, o T y U junto con el grupo -N-C-N- forman un anillo heterocíclico de 5 o 6 miembros saturado o insaturado, que enadicion puede contener un heteroátomo adicional O o S, o el grupohetero-N(alquilo C1-6)-; U es hidrogeno o alquilo C1-6; R2 es hidrogeno o alquilo C1-6; R2es hidrogeno o alquilo C1-6; y R es alquilo C1-20, alquenilo C2-20, alquinilo C2-6, o heterociclilo estando cada uno de estos radicales insustituido osustituidopor uno o más sustituyentes idénticos o diferentes, siendo estos sustituyentes seleccionados a partir del grupo de halogeno, ciano, nitro, hidroxiloalcoxilo C1-6, tioalquilo C1-6, haloalquilo C1-6, haloalcoxilo C1-6 y fenilo; o es cicloalquilo C3-7que está insustituido o mono - o poli-sustituido porsustituyentes idénticos o diferentes seleccionados a partir de halogeno, ciano, nitro, hidroxilo, alquilo C1-6, alquenilo C2-6, alquinilo C2-6, alcoxilo C1-6,tioalquilo V1-6, haloalquilo C1-6, haloalcoxilo C1-20 y fenilo; en donde cada fraccion de fenilo está ella misma insustituida o mono - o poli-sustituida porsustituyentes idénticos o diferentes seleccionados a partir de halogeno, ciano, nitro, hidroxilo, alquilo C1-6, alcoxilo C1-6, tioalquilo C1-6, haloalquiloC1-6 y haloalcoxilo C1-20; o es fenilo, o fenoxifenilo, cada uno de los cuales está insustituido o mono - o poli-sustituido por sustituyentes idénticos o
ARP990105795A 1998-11-17 1999-11-15 N-carboniloximetilesteres de nitroetilendiaminas y nitroguanidinas, proceso para su preparacion, composicion parasiticida, una preparacion en combinacionpara controlar parasitos en animales de sangre caliente, uso de dichos compuestos y compuestos intermediarios para su uso en dicho proceso de prepa AR023703A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH229898 1998-11-17
CH79799 1999-04-29

Publications (1)

Publication Number Publication Date
AR023703A1 true AR023703A1 (es) 2002-09-04

Family

ID=25685711

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990105795A AR023703A1 (es) 1998-11-17 1999-11-15 N-carboniloximetilesteres de nitroetilendiaminas y nitroguanidinas, proceso para su preparacion, composicion parasiticida, una preparacion en combinacionpara controlar parasitos en animales de sangre caliente, uso de dichos compuestos y compuestos intermediarios para su uso en dicho proceso de prepa

Country Status (22)

Country Link
US (3) US6538013B2 (es)
EP (1) EP1131292B1 (es)
JP (1) JP2002529532A (es)
KR (1) KR100620470B1 (es)
CN (1) CN1177823C (es)
AR (1) AR023703A1 (es)
AT (1) ATE317385T1 (es)
AU (1) AU762529B2 (es)
BR (1) BR9915430A (es)
CA (1) CA2350742A1 (es)
CO (1) CO5210925A1 (es)
CY (1) CY1106083T1 (es)
DE (1) DE69929820T2 (es)
DK (1) DK1131292T3 (es)
ES (1) ES2255766T3 (es)
HK (1) HK1038563B (es)
IL (2) IL142687A0 (es)
NZ (1) NZ511380A (es)
PT (1) PT1131292E (es)
RU (1) RU2245877C2 (es)
TW (1) TW561149B (es)
WO (1) WO2000029378A2 (es)

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Also Published As

Publication number Publication date
HK1038563B (en) 2006-11-24
DE69929820T2 (de) 2006-07-27
CO5210925A1 (es) 2002-10-30
BR9915430A (pt) 2001-08-07
RU2245877C2 (ru) 2005-02-10
US20030203891A1 (en) 2003-10-30
PT1131292E (pt) 2006-06-30
US6759407B2 (en) 2004-07-06
WO2000029378A2 (en) 2000-05-25
TW561149B (en) 2003-11-11
HK1038563A1 (en) 2002-03-22
US20020028806A1 (en) 2002-03-07
WO2000029378A3 (en) 2000-12-14
KR100620470B1 (ko) 2006-09-13
CN1326442A (zh) 2001-12-12
EP1131292B1 (en) 2006-02-08
ES2255766T3 (es) 2006-07-01
US20040162283A1 (en) 2004-08-19
AU762529B2 (en) 2003-06-26
IL142687A (en) 2006-10-05
IL142687A0 (en) 2002-03-10
US6538013B2 (en) 2003-03-25
JP2002529532A (ja) 2002-09-10
CN1177823C (zh) 2004-12-01
DK1131292T3 (da) 2006-04-18
DE69929820D1 (de) 2006-04-20
KR20010086445A (ko) 2001-09-12
CA2350742A1 (en) 2000-05-25
AU1553100A (en) 2000-06-05
NZ511380A (en) 2003-10-31
ATE317385T1 (de) 2006-02-15
CY1106083T1 (el) 2011-06-08
US7271184B2 (en) 2007-09-18
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